Published in Intensive Care Med on January 01, 1992
Sepsis, septicaemia, sepsis syndrome, and septic shock: the correct definition and use. Postgrad Med J (1996) 0.85
Sepsis and inflammation: need for clarification. Intensive Care Med (1994) 0.75
Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med (2001) 27.70
Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA (2001) 10.03
Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group. Crit Care Med (1997) 4.86
Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med (2000) 4.74
The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM. Intensive Care Med (1999) 3.93
Serial blood lactate levels can predict the development of multiple organ failure following septic shock. Am J Surg (1996) 3.31
Has the mortality of septic shock changed with time. Crit Care Med (1998) 3.29
Erythropoietin response is blunted in critically ill patients. Intensive Care Med (1997) 3.20
Procalcitonin used as a marker of infection in the intensive care unit. Crit Care Med (1999) 2.93
Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. The CB0006 Sepsis Syndrome Study Group. Crit Care Med (1993) 2.84
Assessment of splanchnic oxygenation by gastric tonometry in patients with acute circulatory failure. JAMA (1993) 2.82
Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest (1993) 2.79
A prospective, randomized, double-blind, controlled clinical trial of enteral immunonutrition in the critically ill. Guy's Hospital Intensive Care Group. Crit Care Med (1998) 2.78
Sedative and analgesic practice in the intensive care unit: the results of a European survey. Br J Anaesth (2001) 2.75
A profile of European intensive care unit physiotherapists. European Society of Intensive Care Medicine. Intensive Care Med (2000) 2.72
Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study. Crit Care Med (2001) 2.56
Methylene blue administration in septic shock: a clinical trial. Crit Care Med (1995) 2.50
Predictive value of microalbuminuria in medical ICU patients: results of a pilot study. Chest (2001) 2.43
The hepatosplanchnic area is not a common source of lactate in patients with severe sepsis. Crit Care Med (2001) 2.34
Pulmonary artery catheterisation--a problem swept under the carpet? Crit Care Resusc (2000) 2.34
An open-label dose escalation study of the nitric oxide synthase inhibitor, N(G)-methyl-L-arginine hydrochloride (546C88), in patients with septic shock. Glaxo Wellcome International Septic Shock Study Group. Crit Care Med (1999) 2.33
Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J Infect Dis (1999) 2.32
Physiotherapy for adult patients with critical illness: recommendations of the European Respiratory Society and European Society of Intensive Care Medicine Task Force on Physiotherapy for Critically Ill Patients. Intensive Care Med (2008) 2.31
Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest (1991) 2.25
Relation between oxygen consumption and oxygen delivery in patients after cardiac surgery. Anesth Analg (1993) 2.12
Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest (1997) 2.07
Interleukin-10 production during septicaemia. Lancet (1994) 2.05
How to use an article on therapy or prevention: pneumonia prevention using subglottic secretion drainage. Crit Care Med (1997) 2.03
Relationship between oxygen uptake and oxygen delivery in septic patients: effects of prostacyclin versus dobutamine. Crit Care Med (1993) 2.00
Effects of methylene blue on oxygen availability and regional blood flow during endotoxic shock. Crit Care Med (1995) 1.97
Serial lactate determinations during circulatory shock. Crit Care Med (1983) 1.93
European participation in major intensive care journals. Intensive Care Med (1995) 1.93
Strong vasopressor support may be futile in the intensive care unit patient with multiple organ failure. Crit Care Med (2000) 1.84
Molecular characterization of an epidemic clone of panantibiotic-resistant Pseudomonas aeruginosa. J Clin Microbiol (2005) 1.83
Central venous catheters-time for a change?. If you put them in properly you don't need to change them routinely. BMJ (1998) 1.82
Effects of vasoactive drugs on gastric intramucosal pH. Crit Care Med (1998) 1.77
Organization of intensive care units in Europe: lessons from the EPIC study. Intensive Care Med (1997) 1.77
Acute neuromuscular respiratory paralysis. J Neurol Neurosurg Psychiatry (1993) 1.72
Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med (2000) 1.70
Application of SOFA score to trauma patients. Sequential Organ Failure Assessment. Intensive Care Med (1999) 1.66
Human cytokine responses to cardiac transplantation and coronary artery bypass grafting. J Thorac Cardiovasc Surg (1996) 1.63
The Brussels sedation scale: use of a simple clinical sedation scale can avoid excessive sedation in patients undergoing mechanical ventilation in the intensive care unit. Br J Anaesth (1999) 1.63
Hemodynamic responses to successful weaning from mechanical ventilation after cardiovascular surgery. Intensive Care Med (2000) 1.62
Estimating left ventricular filling pressure during positive end-expiratory pressure in humans. Am Rev Respir Dis (1991) 1.61
Effects of propofol on human microcirculation. Br J Anaesth (2008) 1.56
Correlation of serial blood lactate levels to organ failure and mortality after trauma. Am J Emerg Med (1995) 1.53
Do established prognostic factors explain the different mortality rates in ICU septic patients around the world? Minerva Anestesiol (2012) 1.53
Molecular epidemiology of an outbreak of multidrug-resistant Enterobacter aerogenes infections and in vivo emergence of imipenem resistance. J Clin Microbiol (1997) 1.51
Coagulopathy induced by hydroxyethyl starch. Anesth Analg (1997) 1.47
Roundtable Conference on Clinical Trials for the Treatment of Sepsis. Brussels, March 12-14, 1994. Chest (1995) 1.47
Comparison of cellulose diacetate and polysulfone membranes in the outcome of acute renal failure. A prospective randomized study. Nephrol Dial Transplant (2000) 1.46
Gastric emptying in the critically ill--the way forward? Intensive Care Med (1997) 1.45
Hypertonic saline solution-hetastarch for fluid resuscitation in experimental septic shock. Anesth Analg (1989) 1.44
Acute respiratory distress syndrome ("ARDS"): no more than a severe acute lung injury? BMJ (1993) 1.43
Doctors' perceptions of the effects of interventions tested in prospective, randomised, controlled, clinical trials: results of a survey of ICU physicians. Intensive Care Med (2001) 1.41
Bretylium tosylate versus lidocaine in experimental cardiac arrest. Am J Emerg Med (1990) 1.39
Atropine administration in experimental electromechanical dissociation. Am J Emerg Med (1992) 1.39
Thermodilution for measurement of cardiac output during artificial ventilation. Intensive Care Med (1988) 1.39
Cardiac tamponade due to spontaneous rupture of right coronary artery aneurysm. Ann Thorac Surg (1996) 1.37
Effects of nitric oxide in septic shock. Am J Respir Crit Care Med (2000) 1.27
Veno-arterial carbon dioxide gradient in human septic shock. Chest (1992) 1.26
Is outcome from ARDS related to the severity of respiratory failure? Eur Respir J (1997) 1.25
Lactate production by the lungs in acute lung injury. Am J Respir Crit Care Med (1997) 1.25
Protecting the gut and the liver in the critically ill: effects of dopexamine. Crit Care Med (1994) 1.20
The effects of vasodilation with prostacyclin on oxygen delivery and uptake in critically ill patients. N Engl J Med (1987) 1.18
Myocardium is a major source of proinflammatory cytokines in patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg (1996) 1.14
A profile of European ICU nursing. Intensive Care Med (1998) 1.13
Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood. Metabolism (1999) 1.10
Blood interleukin 10 levels parallel the severity of septic shock. J Crit Care (1997) 1.09
Combined measurements of blood lactate concentrations and gastric intramucosal pH in patients with severe sepsis. Crit Care Med (1995) 1.09
Arteriovenous differences in PCO2 and pH are good indicators of critical hypoperfusion. Am Rev Respir Dis (1993) 1.08
Cytokine responses to cardiopulmonary bypass: lessons learned from cardiac transplantation. Ann Thorac Surg (1997) 1.07
Disseminated aspergillosis in intensive care unit patients: an autopsy study. J Chemother (2003) 1.07
Is ARDS usually associated with right ventricular dysfunction or failure? Intensive Care Med (1995) 1.07
Does N-acetyl-L-cysteine influence cytokine response during early human septic shock? Chest (1998) 1.07
Thermodilution measurement of right ventricular ejection fraction with a modified pulmonary artery catheter. Intensive Care Med (1986) 1.06
Identification of futility in intensive care. Lancet (1994) 1.05
Effect of positive end-expiratory pressure on right ventricular function in humans. Am Rev Respir Dis (1992) 1.05
Oxygen free radicals in ARDS, septic shock and organ dysfunction. Intensive Care Med (2000) 1.04
Blood lactate levels are better prognostic indicators than TNF and IL-6 levels in patients with septic shock. Intensive Care Med (1996) 1.04
Oxygen supply dependency can characterize septic shock. Intensive Care Med (1998) 1.03
Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock. J Clin Immunol (1995) 1.02
Measurements of right ventricular volumes during fluid challenge. Chest (1990) 1.02
Management of nutrition in European intensive care units: results of a questionnaire. Working Group on Metabolism and Nutrition of the European Society of Intensive Care Medicine. Intensive Care Med (1999) 1.01
Monitoring gastric mucosal carbon dioxide pressure using gas tonometry: in vitro and in vivo validation studies. Anesthesiology (1997) 1.00
Corticosteroids increase blood interleukin-10 levels during cardiopulmonary bypass in men. Surgery (1996) 1.00
The time course of blood C-reactive protein concentrations in relation to the response to initial antimicrobial therapy in patients with sepsis. Infection (2008) 1.00
Lactic acidosis in fulminant hepatic failure. Some aspects of pathogenesis and prognosis. J Hepatol (1985) 1.00
Effect of empiric antibiotic treatment on plasma endotoxin activity in septic patients. Infection (2014) 0.98
Power spectral analysis of cardiovascular variability in critically ill neurosurgical patients. Crit Care Med (2000) 0.96
Protective effects of N-acetyl-L-cysteine in endotoxemia. Am J Physiol (1994) 0.96
Continuous venovenous hemofiltration improves cardiac performance by mechanisms other than tumor necrosis factor-alpha attenuation during endotoxic shock. Crit Care Med (1999) 0.96
Effects of converting enzyme inhibitor on hepatic blood flow in man. Am J Med (1984) 0.96
Lactate/pyruvate ratio as a marker of tissue hypoxia in circulatory and septic shock. Anaesth Intensive Care (2012) 0.95
Controlled hyperventilation in the prevention of cerebral oedema in fulminant hepatic failure. J Hepatol (1986) 0.95
Earlier identification of patients at risk from acetaminophen-induced acute liver failure. Crit Care Med (1998) 0.95
Oxygen extraction is altered by endotoxin during tamponade-induced stagnant hypoxia in the dog. Circ Shock (1993) 0.94
The use of intermittent and continuous recordings of jugular venous bulb oxygen saturation in the unconscious patient. Scand J Clin Lab Invest Suppl (1987) 0.94
Association of tumor necrosis factor-2 allele with plasma tumor necrosis factor-alpha levels and mortality from septic shock. Am J Med (2001) 0.94
Do we need intermediate care units? Intensive Care Med (1999) 0.94