Measurements of right ventricular volumes during fluid challenge.

Using heart-lung interactions to assess fluid responsiveness during mechanical ventilation. Crit Care (2000) 1.73

The right ventricle: interaction with the pulmonary circulation. Crit Care (2016) 1.39

Clinical relevance of data from the pulmonary artery catheter. Crit Care (2006) 1.24

Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review. Crit Care (2010) 1.18

Continuously assessed right ventricular end-diastolic volume as a marker of cardiac preload and fluid responsiveness in mechanically ventilated cardiac surgical patients. Crit Care (2005) 0.86

Stroke volume variation for prediction of fluid responsiveness in patients undergoing gastrointestinal surgery. Int J Med Sci (2013) 0.83

My paper 20 years later: Effect of positive end-expiratory pressure on right ventricular function in humans. Intensive Care Med (2014) 0.81

Transoesophageal Doppler compared to central venous pressure for perioperative hemodynamic monitoring and fluid guidance in liver resection. Saudi J Anaesth (2013) 0.79

Effect of rapid plasma volume expansion during anesthesia induction on haemodynamics and oxygen balance in patients undergoing gastrointestinal surgery. Int J Med Sci (2013) 0.78

Hemodynamic monitoring during liver transplantation: A state of the art review. World J Hepatol (2015) 0.76

Functional hemodynamic monitoring. Crit Care Clin (2015) 0.76

The comparison of stroke volume variation with central venous pressure in predicting fluid responsiveness in septic patients with acute circulatory failure. Indian J Crit Care Med (2015) 0.75

Year in review 2005: critical care--cardiology. Crit Care (2006) 0.75

Characteristics of hemodynamic disorders in patients with severe traumatic brain injury. Crit Care Res Pract (2012) 0.75

Expert consensus document: Echocardiography and lung ultrasonography for the assessment and management of acute heart failure. Nat Rev Cardiol (2017) 0.75

Non-Invasive Respiratory Impedance Enhances Cerebral Perfusion in Healthy Adults. Front Neurol (2017) 0.75

Therapeutic hypertension: principles and methods. Neurosurg Rev (2004) 0.75

Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med (2001) 46.58

Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med (2001) 27.70

Serial evaluation of the SOFA score to predict outcome in critically ill patients. JAMA (2001) 10.03

Relation between respiratory changes in arterial pulse pressure and fluid responsiveness in septic patients with acute circulatory failure. Am J Respir Crit Care Med (2000) 5.53

Confirmatory interleukin-1 receptor antagonist trial in severe sepsis: a phase III, randomized, double-blind, placebo-controlled, multicenter trial. The Interleukin-1 Receptor Antagonist Sepsis Investigator Group. Crit Care Med (1997) 4.86

Acute renal failure in the ICU: risk factors and outcome evaluated by the SOFA score. Intensive Care Med (2000) 4.74

The use of maximum SOFA score to quantify organ dysfunction/failure in intensive care. Results of a prospective, multicentre study. Working Group on Sepsis related Problems of the ESICM. Intensive Care Med (1999) 3.93

Serial blood lactate levels can predict the development of multiple organ failure following septic shock. Am J Surg (1996) 3.31

Has the mortality of septic shock changed with time. Crit Care Med (1998) 3.29

Long-term outcome of critically ill elderly patients requiring intensive care. JAMA (1993) 3.27

Erythropoietin response is blunted in critically ill patients. Intensive Care Med (1997) 3.20

Procalcitonin used as a marker of infection in the intensive care unit. Crit Care Med (1999) 2.93

Influence of an anti-tumor necrosis factor monoclonal antibody on cytokine levels in patients with sepsis. The CB0006 Sepsis Syndrome Study Group. Crit Care Med (1993) 2.84

Serum cytokine levels in human septic shock. Relation to multiple-system organ failure and mortality. Chest (1993) 2.79

Sedative and analgesic practice in the intensive care unit: the results of a European survey. Br J Anaesth (2001) 2.75

A profile of European intensive care unit physiotherapists. European Society of Intensive Care Medicine. Intensive Care Med (2000) 2.72

Randomized, placebo-controlled trial of the anti-tumor necrosis factor antibody fragment afelimomab in hyperinflammatory response during severe sepsis: The RAMSES Study. Crit Care Med (2001) 2.56

Methylene blue administration in septic shock: a clinical trial. Crit Care Med (1995) 2.50

Predictive value of microalbuminuria in medical ICU patients: results of a pilot study. Chest (2001) 2.43

The hepatosplanchnic area is not a common source of lactate in patients with severe sepsis. Crit Care Med (2001) 2.34

An open-label dose escalation study of the nitric oxide synthase inhibitor, N(G)-methyl-L-arginine hydrochloride (546C88), in patients with septic shock. Glaxo Wellcome International Septic Shock Study Group. Crit Care Med (1999) 2.33

Relationship between plasma levels of lipopolysaccharide (LPS) and LPS-binding protein in patients with severe sepsis and septic shock. J Infect Dis (1999) 2.32

Physiotherapy for adult patients with critical illness: recommendations of the European Respiratory Society and European Society of Intensive Care Medicine Task Force on Physiotherapy for Critically Ill Patients. Intensive Care Med (2008) 2.31

Clinical use of respiratory changes in arterial pulse pressure to monitor the hemodynamic effects of PEEP. Am J Respir Crit Care Med (1999) 2.28

Blood lactate levels are superior to oxygen-derived variables in predicting outcome in human septic shock. Chest (1991) 2.25

Quality-adjusted survival in the first year after the acute respiratory distress syndrome. Am J Respir Crit Care Med (2001) 2.18

Diffusive vs. convective therapy: effects on mediators of inflammation in patient with severe systemic inflammatory response syndrome. Crit Care Med (1998) 2.14

Relation between oxygen consumption and oxygen delivery in patients after cardiac surgery. Anesth Analg (1993) 2.12

Strong ion gap: a methodology for exploring unexplained anions. J Crit Care (1995) 2.09

Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategies. Chest (1997) 2.07

Interleukin-10 production during septicaemia. Lancet (1994) 2.05

How to use an article on therapy or prevention: pneumonia prevention using subglottic secretion drainage. Crit Care Med (1997) 2.03

Effect of intrathoracic pressure on left ventricular performance. N Engl J Med (1979) 2.01

Relationship between oxygen uptake and oxygen delivery in septic patients: effects of prostacyclin versus dobutamine. Crit Care Med (1993) 2.00

Effects of methylene blue on oxygen availability and regional blood flow during endotoxic shock. Crit Care Med (1995) 1.97

Serial lactate determinations during circulatory shock. Crit Care Med (1983) 1.93

European participation in major intensive care journals. Intensive Care Med (1995) 1.93

Strong vasopressor support may be futile in the intensive care unit patient with multiple organ failure. Crit Care Med (2000) 1.84

Molecular characterization of an epidemic clone of panantibiotic-resistant Pseudomonas aeruginosa. J Clin Microbiol (2005) 1.83

Effects of vasoactive drugs on gastric intramucosal pH. Crit Care Med (1998) 1.77

The American-European Consensus Conference on ARDS, part 2: Ventilatory, pharmacologic, supportive therapy, study design strategies, and issues related to recovery and remodeling. Acute respiratory distress syndrome. Am J Respir Crit Care Med (1998) 1.71

Consensus conference definitions for sepsis, septic shock, acute lung injury, and acute respiratory distress syndrome: time for a reevaluation. Crit Care Med (2000) 1.70

Application of SOFA score to trauma patients. Sequential Organ Failure Assessment. Intensive Care Med (1999) 1.66

Release of lactate by the lung in acute lung injury. Chest (1997) 1.66

Quantifying learning in medical students during a critical care medicine elective: a comparison of three evaluation instruments. Crit Care Med (2001) 1.65

Human cytokine responses to cardiac transplantation and coronary artery bypass grafting. J Thorac Cardiovasc Surg (1996) 1.63

The Brussels sedation scale: use of a simple clinical sedation scale can avoid excessive sedation in patients undergoing mechanical ventilation in the intensive care unit. Br J Anaesth (1999) 1.63

Hemodynamic responses to successful weaning from mechanical ventilation after cardiovascular surgery. Intensive Care Med (2000) 1.62

Estimating left ventricular filling pressure during positive end-expiratory pressure in humans. Am Rev Respir Dis (1991) 1.61

Estimating cardiac filling pressure in mechanically ventilated patients with hyperinflation. Crit Care Med (2000) 1.57

Effects of propofol on human microcirculation. Br J Anaesth (2008) 1.56

Correlation of serial blood lactate levels to organ failure and mortality after trauma. Am J Emerg Med (1995) 1.53

Outcomes research in critical care: results of the American Thoracic Society Critical Care Assembly Workshop on Outcomes Research. The Members of the Outcomes Research Workshop. Am J Respir Crit Care Med (1999) 1.53

Do established prognostic factors explain the different mortality rates in ICU septic patients around the world? Minerva Anestesiol (2012) 1.53

Molecular epidemiology of an outbreak of multidrug-resistant Enterobacter aerogenes infections and in vivo emergence of imipenem resistance. J Clin Microbiol (1997) 1.51

Sepsis, severe sepsis or sepsis syndrome: need for clarification. Intensive Care Med (1992) 1.48

Coagulopathy induced by hydroxyethyl starch. Anesth Analg (1997) 1.47

Roundtable Conference on Clinical Trials for the Treatment of Sepsis. Brussels, March 12-14, 1994. Chest (1995) 1.47

Comparison of cellulose diacetate and polysulfone membranes in the outcome of acute renal failure. A prospective randomized study. Nephrol Dial Transplant (2000) 1.46

Assessment of left ventricular contractile state by preload-adjusted maximal power using echocardiographic automated border detection. J Am Coll Cardiol (1998) 1.45

Hypertonic saline solution-hetastarch for fluid resuscitation in experimental septic shock. Anesth Analg (1989) 1.44

Defining the hypoxic threshold. Crit Care Med (1991) 1.44

Quantitative assessment of alterations in regional left ventricular contractility with color-coded tissue Doppler echocardiography. Comparison with sonomicrometry and pressure-volume relations. Circulation (1997) 1.43

Prostaglandin E1 infusion for right ventricular failure after cardiac transplantation. J Thorac Cardiovasc Surg (1992) 1.42

Mitochondrial membrane potential and apoptosis peripheral blood monocytes in severe human sepsis. Am J Respir Crit Care Med (2001) 1.41

Doctors' perceptions of the effects of interventions tested in prospective, randomised, controlled, clinical trials: results of a survey of ICU physicians. Intensive Care Med (2001) 1.41

NF-kappaB expression in mononuclear cells of patients with sepsis resembles that observed in lipopolysaccharide tolerance. Am J Respir Crit Care Med (2000) 1.41

Atropine administration in experimental electromechanical dissociation. Am J Emerg Med (1992) 1.39

Bretylium tosylate versus lidocaine in experimental cardiac arrest. Am J Emerg Med (1990) 1.39

Thermodilution for measurement of cardiac output during artificial ventilation. Intensive Care Med (1988) 1.39

Respiratory sinus arrhythmia in the denervated human heart. J Appl Physiol (1985) (1989) 1.39

Cardiac tamponade due to spontaneous rupture of right coronary artery aneurysm. Ann Thorac Surg (1996) 1.37

The effect of managed care on ICU length of stay: implications for medicare. JAMA (1996) 1.35

The American-European Consensus Conference on ARDS, part 2. Ventilatory, pharmacologic, supportive therapy, study design strategies and issues related to recovery and remodeling. Intensive Care Med (1998) 1.32

Effects of nitric oxide in septic shock. Am J Respir Crit Care Med (2000) 1.27

Veno-arterial carbon dioxide gradient in human septic shock. Chest (1992) 1.26

Is outcome from ARDS related to the severity of respiratory failure? Eur Respir J (1997) 1.25

Lactate production by the lungs in acute lung injury. Am J Respir Crit Care Med (1997) 1.25

Etiology of metabolic acidosis during saline resuscitation in endotoxemia. Shock (1998) 1.25

The effect of intensive plasma water exchange by hemofiltration on hemodynamics and soluble mediators in canine endotoxemia. Am J Respir Crit Care Med (2000) 1.22

Determinants of pulmonary arterial flow variation during respiration. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.20

Postreperfusion syndrome: cardiovascular collapse following hepatic reperfusion during liver transplantation. Transplant Proc (1987) 1.17

Postreperfusion syndrome: hypotension after reperfusion of the transplanted liver. J Crit Care (1993) 1.15

Instantaneous venous return curves in an intact canine preparation. J Appl Physiol Respir Environ Exerc Physiol (1984) 1.15

Myocardium is a major source of proinflammatory cytokines in patients undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg (1996) 1.14

Short-term and long-term outcome prediction with the Acute Physiology and Chronic Health Evaluation II system after orthotopic liver transplantation. Crit Care Med (2000) 1.14

A profile of European ICU nursing. Intensive Care Med (1998) 1.13

Current understanding of sepsis. Clin Infect Dis (1996) 1.10

Leukocyte glycolysis and lactate output in animal sepsis and ex vivo human blood. Metabolism (1999) 1.10

Blood interleukin 10 levels parallel the severity of septic shock. J Crit Care (1997) 1.09

Medical students can learn the basic application, analytic, evaluative, and psychomotor skills of critical care medicine. Crit Care Med (2000) 1.09

Combined measurements of blood lactate concentrations and gastric intramucosal pH in patients with severe sepsis. Crit Care Med (1995) 1.09

The inflammatory balance in human sepsis. Intensive Care Med (2000) 1.08

Arteriovenous differences in PCO2 and pH are good indicators of critical hypoperfusion. Am Rev Respir Dis (1993) 1.08

Cytokine responses to cardiopulmonary bypass: lessons learned from cardiac transplantation. Ann Thorac Surg (1997) 1.07

Technology comparison studies require precise reference controls to be valid. Br J Anaesth (2013) 1.07

Disseminated aspergillosis in intensive care unit patients: an autopsy study. J Chemother (2003) 1.07

Is ARDS usually associated with right ventricular dysfunction or failure? Intensive Care Med (1995) 1.07

Does N-acetyl-L-cysteine influence cytokine response during early human septic shock? Chest (1998) 1.07

Thermodilution measurement of right ventricular ejection fraction with a modified pulmonary artery catheter. Intensive Care Med (1986) 1.06