Bipolar disorder.

Unmasking of brugada syndrome by lithium. Circulation (2005) 2.30

Lithium nephrotoxicity revisited. Nat Rev Nephrol (2009) 1.92

SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties. Nature (2013) 1.86

Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers. Neuropsychopharmacology (2008) 1.79

Glycogen synthase kinase-3 (GSK3) in psychiatric diseases and therapeutic interventions. Curr Drug Targets (2006) 1.78

A review of empirically supported psychological therapies for mood disorders in adults. Depress Anxiety (2010) 1.50

Glycogen synthase kinase-3 in the etiology and treatment of mood disorders. Front Mol Neurosci (2011) 1.48

Evidence for the involvement of the kainate receptor subunit GluR6 (GRIK2) in mediating behavioral displays related to behavioral symptoms of mania. Mol Psychiatry (2008) 1.36

GSK-3 and Wnt Signaling in Neurogenesis and Bipolar Disorder. Front Mol Neurosci (2012) 1.34

Bipolar disorder and mechanisms of action of mood stabilizers. Brain Res Rev (2009) 1.31

BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments. Proc Natl Acad Sci U S A (2008) 1.25

Bipolar disorder: from genes to behavior pathways. J Clin Invest (2009) 1.24

Asenapine. Nat Rev Drug Discov (2009) 1.21

Lithium reduces tau phosphorylation but not A beta or working memory deficits in a transgenic model with both plaques and tangles. Am J Pathol (2007) 1.21

The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement. Mol Psychiatry (2008) 1.19

Migraine and psychiatric disorders: comorbidities, mechanisms, and clinical applications. Neurol Sci (2009) 1.15

Calbindin D28k targets myo-inositol monophosphatase in spines and dendrites of cerebellar Purkinje neurons. Proc Natl Acad Sci U S A (2005) 1.12

G protein-coupled receptors in major psychiatric disorders. Biochim Biophys Acta (2006) 1.12

Chronic olanzapine treatment decreases arachidonic acid turnover and prostaglandin E₂ concentration in rat brain. J Neurochem (2011) 1.02

Lithium modifies brain arachidonic and docosahexaenoic metabolism in rat lipopolysaccharide model of neuroinflammation. J Lipid Res (2009) 0.99

3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder. J Psychiatry Neurosci (2009) 0.97

Evidence for involvement of ERK, PI3K, and RSK in induction of Bcl-2 by valproate. J Mol Neurosci (2008) 0.95

Reverse translational strategies for developing animal models of bipolar disorder. Dis Model Mech (2009) 0.94

Investigation of serum high-sensitive C-reactive protein levels across all mood states in bipolar disorder. Eur Arch Psychiatry Clin Neurosci (2008) 0.94

Translational research in bipolar disorder: emerging insights from genetically based models. Mol Psychiatry (2010) 0.91

Phosphorylation regulates myo-inositol-3-phosphate synthase: a novel regulatory mechanism of inositol biosynthesis. J Biol Chem (2013) 0.91

Altered concentrations of amyloid precursor protein metabolites in the cerebrospinal fluid of patients with bipolar disorder. Neuropsychopharmacology (2012) 0.90

Effects of lithium on inflammation. ACS Chem Neurosci (2014) 0.89

Review: magnetic resonance spectroscopy studies of pediatric major depressive disorder. Depress Res Treat (2010) 0.89

Mood-stabilizers target the brain arachidonic acid cascade. Curr Mol Pharmacol (2009) 0.89

Antioxidants as potential therapeutics for neuropsychiatric disorders. Prog Neuropsychopharmacol Biol Psychiatry (2012) 0.89

Disturbed resting state EEG synchronization in bipolar disorder: A graph-theoretic analysis. Neuroimage Clin (2013) 0.88

Enhanced peripheral toll-like receptor responses in psychosis: further evidence of a pro-inflammatory phenotype. Transl Psychiatry (2011) 0.88

Effects of mood stabilizers on DNA damage in an animal model of mania. J Psychiatry Neurosci (2008) 0.88

Optical drug monitoring: photoacoustic imaging of nanosensors to monitor therapeutic lithium in vivo. ACS Nano (2015) 0.86

Cortical thickness differences between bipolar depression and major depressive disorder. Bipolar Disord (2014) 0.85

Elevated concentrations of neurofilament light chain in the cerebrospinal fluid of bipolar disorder patients. Neuropsychopharmacology (2014) 0.85

Lithium nephrotoxicity. Int J Bipolar Disord (2015) 0.85

Relative hypo- and hypercortisolism are both associated with depression and lower quality of life in bipolar disorder: a cross-sectional study. PLoS One (2014) 0.85

Pain complaints in adolescent patients with affective disorders versus adolescent psychiatric controls. Prim Care Companion J Clin Psychiatry (2005) 0.84

Influence of family history of major depression, bipolar disorder, and suicide on clinical features in patients with major depression and bipolar disorder. Eur Arch Psychiatry Clin Neurosci (2012) 0.84

Higher pretreatment 5-HT1A receptor binding potential in bipolar disorder depression is associated with treatment remission: a naturalistic treatment pilot PET study. Synapse (2013) 0.83

Revisiting loxapine: a systematic review. Ann Gen Psychiatry (2015) 0.83

The prevalence of bipolar disorder in primary care patients with depression or other psychiatric complaints: a systematic review. Psychosomatics (2013) 0.82

Genome-wide parametric linkage analyses of 644 bipolar pedigrees suggest susceptibility loci at chromosomes 16 and 20. Psychiatr Genet (2008) 0.82

A review of bipolar disorder in adults. Psychiatry (Edgmont) (2006) 0.82

Positive association between the PDLIM5 gene and bipolar disorder in the Chinese Han population. J Psychiatry Neurosci (2009) 0.82

Interaction networks of lithium and valproate molecular targets reveal a striking enrichment of apoptosis functional clusters and neurotrophin signaling. Pharmacogenomics J (2011) 0.81

Cerebrospinal fluid metabolomics identifies a key role of isocitrate dehydrogenase in bipolar disorder: evidence in support of mitochondrial dysfunction hypothesis. Mol Psychiatry (2016) 0.81

Monocyte and microglial activation in patients with mood-stabilized bipolar disorder. J Psychiatry Neurosci (2015) 0.81

Amphetamine-induced appetitive 50-kHz calls in rats: a marker of affect in mania? Psychopharmacology (Berl) (2014) 0.80

Neuronal peroxisome proliferator-activated receptor gamma signaling: regulation by mood-stabilizer valproate. J Mol Neurosci (2008) 0.79

Transcription factor SP4 phosphorylation is altered in the postmortem cerebellum of bipolar disorder and schizophrenia subjects. Eur Neuropsychopharmacol (2015) 0.78

Oxcarbazepine-induced immunoglobulin deficiency. Clin Diagn Lab Immunol (2005) 0.78

Valproate Induces the Unfolded Protein Response by Increasing Ceramide Levels. J Biol Chem (2016) 0.78

Perturbation of the Vacuolar ATPase: A NOVEL CONSEQUENCE OF INOSITOL DEPLETION. J Biol Chem (2015) 0.78

Decreased cerebrospinal fluid secretogranin II concentrations in severe forms of bipolar disorder. J Psychiatry Neurosci (2013) 0.78

Translating Science Into Service: Lessons Learned From the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Study. Prim Care Companion J Clin Psychiatry (2007) 0.78

Incurring greater health care costs: risk stratification of employees with bipolar disorder. Prim Care Companion J Clin Psychiatry (2006) 0.78

Acute and chronic effects of lithium on BDNF and GDNF mRNA and protein levels in rat primary neuronal, astroglial and neuroastroglia cultures. Iran J Basic Med Sci (2015) 0.77

Investigating the mechanism(s) underlying switching between states in bipolar disorder. Eur J Pharmacol (2015) 0.77

Cost-effectiveness of asenapine in the treatment of bipolar disorder in Canada. BMC Psychiatry (2014) 0.77

Evaluation of brain creatine kinase activity in an animal model of mania induced by ouabain. J Neural Transm (Vienna) (2010) 0.76

The presentation, recognition and management of bipolar depression in primary care. J Gen Intern Med (2013) 0.76

Sodium valproate inhibits the growth of human cholangiocarcinoma in vitro and in vivo. Gastroenterol Res Pract (2013) 0.76

Managing bipolar depression. Psychiatry (Edgmont) (2006) 0.76

Partial rodent genetic models for bipolar disorder. Curr Top Behav Neurosci (2011) 0.76

Treatment implications of predominant polarity and the polarity index: a comprehensive review. Int J Neuropsychopharmacol (2014) 0.76

Abnormal development of monoaminergic neurons is implicated in mood fluctuations and bipolar disorder. Neuropsychopharmacology (2014) 0.76

M-current preservation contributes to anticonvulsant effects of valproic acid. J Clin Invest (2015) 0.76

Na+,K+-ATPase activity in an animal model of mania. J Neural Transm (Vienna) (2009) 0.75

A Review of Biomarkers in Mood and Psychotic Disorders: A Dissection of Clinical vs. Preclinical Correlates. Curr Neuropharmacol (2015) 0.75

The association of sleep and physical activity with integrity of white matter microstructure in bipolar disorder patients and healthy controls. Psychiatry Res (2017) 0.75

An actigraphy study investigating sleep in bipolar I patients, unaffected siblings and controls. J Affect Disord (2016) 0.75

Carbamazepine extended-release capsules in bipolar disorder. Neuropsychiatr Dis Treat (2006) 0.75

Bipolar disorder. N Engl J Med (2004) 0.75

Supra-therapeutic plasma concentrations of haloperidol induce moderate inhibition of lipopolysaccharide-induced interleukin-8 release in human monocytes. Ann Transl Med (2016) 0.75

Effects of Acute Lithium Treatment on Brain Levels of Inflammatory Mediators in Poststroke Rats. Biomed Res Int (2015) 0.75

Mean platelet volume in bipolar disorder: the search for an ideal biomarker. Neuropsychiatr Dis Treat (2016) 0.75

Role of Hybrid Brain Imaging in Neuropsychiatric Disorders. Diagnostics (Basel) (2015) 0.75

Personality traits in bipolar disorder and influence on outcome. BMC Psychiatry (2017) 0.75

Large-scale interaction effects reveal missing heritability in schizophrenia, bipolar disorder and posttraumatic stress disorder. Transl Psychiatry (2017) 0.75

Treatment of bipolar disorders during pregnancy: maternal and fetal safety and challenges. Drug Healthc Patient Saf (2014) 0.75

Inositol depletion induced by acute treatment of the bipolar disorder drug valproate increases levels of phytosphingosine. J Biol Chem (2017) 0.75

The Energy Metabolism Dysfunction in Psychiatric Disorders Postmortem Brains: Focus on Proteomic Evidence. Front Neurosci (2017) 0.75

BACE1 inhibition by microdose lithium formulation NP03 rescues memory loss and early stage amyloid neuropathology. Transl Psychiatry (2017) 0.75

Peripheral zinc and neopterin concentrations are associated with mood severity in bipolar disorder in a gender-specific manner. Psychiatry Res (2017) 0.75

Antipsychotics possessing antidepressive efficacy increase Golf protein in rat striatum. Psychopharmacology (Berl) (2008) 0.75

The inositol monophosphatase inhibitor L-690,330 affects pilocarpine-behavior and the forced swim test. Psychopharmacology (Berl) (2013) 0.75