Robert H Schiestl

Author PubWeight™ 79.54‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2007 5.62
2 Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res 2004 2.33
3 Intestinal mucosal inflammation leads to systemic genotoxicity in mice. Cancer Res 2009 1.90
4 Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2007 1.89
5 Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2007 1.76
6 Radiation-induced long-lived extracellular radicals do not contribute to measurement of intracellular reactive oxygen species using the dichlorofluorescein method. Radiat Res 2008 1.71
7 Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice. Cancer Res 2009 1.71
8 Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2007 1.48
9 Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res 2004 1.43
10 Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA Repair (Amst) 2006 1.32
11 New and emerging technologies for genetic toxicity testing. Environ Mol Mutagen 2010 1.28
12 Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes. Dev Neurobiol 2008 1.27
13 WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair. Aging Cell 2003 1.23
14 Lack of WRN results in extensive deletion at nonhomologous joining ends. Cancer Res 2002 1.18
15 Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. Cancer Res 2010 1.17
16 Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res 2003 1.17
17 Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice. J Nutr 2007 1.07
18 Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res 2010 1.06
19 siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status. Radiat Res 2006 1.05
20 Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations. Radiat Res 2008 1.04
21 Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant. Gene 2002 1.03
22 Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae. Nucleic Acids Res 2007 1.01
23 Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis 2005 1.01
24 Involvement of homologous recombination in carcinogenesis. Adv Genet 2007 0.99
25 Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc 2007 0.98
26 Differences in animal housing facilities and diet may affect study outcomes-a plea for inclusion of such information in publications. DNA Repair (Amst) 2006 0.97
27 Role of homologous recombination in carcinogenesis. Exp Mol Pathol 2003 0.96
28 Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice. Mutat Res 2005 0.96
29 Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity. Cancer Res 2013 0.90
30 N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals. Mutat Res 2009 0.90
31 Increases in oxidative stress in the progeny of X-irradiated cells. Radiat Res 2004 0.90
32 High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol 2011 0.90
33 Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae. DNA Repair (Amst) 2008 0.90
34 Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases. PLoS One 2012 0.89
35 Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine. DNA Repair (Amst) 2006 0.88
36 Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae. Genetics 2003 0.88
37 Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. DNA Repair (Amst) 2005 0.88
38 Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice. Int J Cancer 2011 0.87
39 Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food Chem Toxicol 2007 0.84
40 Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res 2007 0.84
41 Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res 2010 0.84
42 In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol 2004 0.84
43 Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Mol Neurodegener 2011 0.83
44 Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. J Nucl Med 2010 0.83
45 Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion. Nucleic Acids Res 2002 0.82
46 Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice. Mutat Res 2008 0.82
47 Experimental antioxidant therapy in ataxia telangiectasia. Clin Med Oncol 2008 0.81
48 Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells. Radiat Res 2009 0.81
49 The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity. Mutagenesis 2011 0.81
50 Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment. Toxicol Sci 2007 0.80
51 A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro. Drug Chem Toxicol 2011 0.80
52 Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice. Cancer Res 2006 0.80
53 IL-13 overexpression in mouse lungs triggers systemic genotoxicity in peripheral blood. Mutat Res 2014 0.80
54 Mouse models for induced genetic instability at endogenous loci. Oncogene 2003 0.80
55 Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Exp Hematol 2011 0.80
56 Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae. Mol Genet Genomics 2010 0.79
57 Detecting carcinogens with the yeast DEL assay. Methods Mol Biol 2004 0.79
58 Intestinal microbiome and lymphoma development. Cancer J 2014 0.79
59 More damaging than we think: systemic effects of intestinal inflammation. Cell Cycle 2009 0.79
60 Yeast DEL assay detects clastogens. Mutat Res 2005 0.79
61 9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae. Toxicol In Vitro 2007 0.78
62 Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst) 2004 0.78
63 Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries. Mutat Res 2007 0.78
64 2-Dodecylcyclobutanone does not induce mutations in the Salmonella mutagenicity test or intrachromosomal recombination in Saccharomyces cerevisiae. J Food Prot 2004 0.78
65 Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons. Radiat Res 2014 0.77
66 Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells. Mutat Res 2013 0.77
67 Radiation-induced myeloid leukemia in murine models. Hum Genomics 2014 0.77
68 Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae. Radiat Res 2009 0.77
69 Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Environ Mol Mutagen 2011 0.77
70 Heat-induced phosphorylation of NBS1 in human skin fibroblast cells. J Cell Biochem 2006 0.77
71 Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae. Radiat Res 2010 0.77
72 Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version. Radiat Res 2010 0.76
73 Effect of benzene and its closed ring metabolites on intrachromosomal recombination in Saccharomyces cerevisiae. Mutat Res 2005 0.76
74 Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae. DNA Repair (Amst) 2004 0.76
75 The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent. J Biomed Biotechnol 2009 0.76
76 Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae. Mol Genet Genomics 2011 0.76
77 Biological aspects of dichlorofluorescein measurement of cellular reactive oxygen species. Radiat Res 2008 0.75
78 Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res 2006 0.75
79 HNO induces DNA deletions in the yeast S. cerevisiae. Mutat Res 2007 0.75
80 Mouse models for radiation-induced cancers. Mutagenesis 2016 0.75
81 Mutagen X and chlorinated tap water are recombinagenic in yeast. Mutat Res 2004 0.75
82 Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice. Radiat Res 2010 0.75