Published in Adv Genet on January 01, 2007
RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci. Genes Dev (2011) 2.00
Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo. J Cell Biol (2009) 1.29
DNA repair by homologous recombination, but not by nonhomologous end joining, is elevated in breast cancer cells. Neoplasia (2009) 1.24
Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity. Carcinogenesis (2008) 1.10
Cancer risk at low doses of ionizing radiation: artificial neural networks inference from atomic bomb survivors. J Radiat Res (2013) 1.06
Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation. Nucleic Acids Res (2012) 0.98
Recombination phenotypes of the NCI-60 collection of human cancer cells. BMC Mol Biol (2011) 0.87
ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells. PLoS One (2011) 0.85
Rosa26-GFP direct repeat (RaDR-GFP) mice reveal tissue- and age-dependence of homologous recombination in mammals in vivo. PLoS Genet (2014) 0.84
Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res (2010) 0.84
RAD51 can inhibit PDGF-B-induced gliomagenesis and genomic instability. Neuro Oncol (2011) 0.82
Investigation of the effects of aging on homologous recombination in long-term bone marrow cultures. In Vivo (2009) 0.80
Comparison of proliferation and genomic instability responses to WRN silencing in hematopoietic HL60 and TK6 cells. PLoS One (2011) 0.80
Detailed genome-wide SNP analysis of major salivary carcinomas localizes subtype-specific chromosome sites and oncogenes of potential clinical significance. Am J Pathol (2013) 0.80
Lympho-vascular invasion in BRCA related breast cancer compared to sporadic controls. BMC Cancer (2010) 0.78
A Novel Role of Chromodomain Protein CBX8 in DNA Damage Response. J Biol Chem (2016) 0.78
Canonical DNA Repair Pathways Influence R-Loop-Driven Genome Instability. J Mol Biol (2016) 0.77
Pomegranate Intake Protects Against Genomic Instability Induced by Medical X-rays In Vivo in Mice. Nutr Cancer (2016) 0.75
Estrogen Effects on the Mammary Gland in Early and Late Life and Breast Cancer Risk. Front Oncol (2017) 0.75
High-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc (2007) 5.62
Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress. Science (2012) 2.56
Models for evaluating agents intended for the prophylaxis, mitigation and treatment of radiation injuries. Report of an NCI Workshop, December 3-4, 2003. Radiat Res (2004) 2.33
Intestinal mucosal inflammation leads to systemic genotoxicity in mice. Cancer Res (2009) 1.90
Quick and easy yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc (2007) 1.89
Large-scale high-efficiency yeast transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc (2007) 1.76
Radiation-induced long-lived extracellular radicals do not contribute to measurement of intracellular reactive oxygen species using the dichlorofluorescein method. Radiat Res (2008) 1.71
Titanium dioxide nanoparticles induce DNA damage and genetic instability in vivo in mice. Cancer Res (2009) 1.71
Frozen competent yeast cells that can be transformed with high efficiency using the LiAc/SS carrier DNA/PEG method. Nat Protoc (2007) 1.48
Effect of N-acetyl cysteine on oxidative DNA damage and the frequency of DNA deletions in atm-deficient mice. Cancer Res (2004) 1.43
Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice. DNA Repair (Amst) (2006) 1.32
New and emerging technologies for genetic toxicity testing. Environ Mol Mutagen (2010) 1.28
Sex difference in neural tube defects in p53-null mice is caused by differences in the complement of X not Y genes. Dev Neurobiol (2008) 1.27
Building and analyzing protein interactome networks by cross-species comparisons. BMC Syst Biol (2010) 1.27
WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair. Aging Cell (2003) 1.23
Lack of WRN results in extensive deletion at nonhomologous joining ends. Cancer Res (2002) 1.18
Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation. Cancer Res (2010) 1.17
Atm-, p53-, and Gadd45a-deficient mice show an increased frequency of homologous recombination at different stages during development. Cancer Res (2003) 1.17
A network of conserved damage survival pathways revealed by a genomic RNAi screen. PLoS Genet (2009) 1.16
Reducing confounding and suppression effects in TCGA data: an integrated analysis of chemotherapy response in ovarian cancer. BMC Genomics (2012) 1.08
Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice. J Nutr (2007) 1.07
An analysis of normalization methods for Drosophila RNAi genomic screens and development of a robust validation scheme. J Biomol Screen (2008) 1.07
Mechanisms of intestinal inflammation and development of associated cancers: lessons learned from mouse models. Mutat Res (2010) 1.06
siRNA targeting NBS1 or XIAP increases radiation sensitivity of human cancer cells independent of TP53 status. Radiat Res (2006) 1.05
Dissection of a mouse eye for a whole mount of the retinal pigment epithelium. J Vis Exp (2011) 1.05
Refinement of the dichlorofluorescein assay for flow cytometric measurement of reactive oxygen species in irradiated and bystander cell populations. Radiat Res (2008) 1.04
Detection of Arabidopsis thaliana AtRAD1 cDNA variants and assessment of function by expression in a yeast rad1 mutant. Gene (2002) 1.03
PARP1 suppresses homologous recombination events in mice in vivo. Nucleic Acids Res (2010) 1.02
Ionizing radiation and restriction enzymes induce microhomology-mediated illegitimate recombination in Saccharomyces cerevisiae. Nucleic Acids Res (2007) 1.01
Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis (2005) 1.01
Microtiter plate transformation using the LiAc/SS carrier DNA/PEG method. Nat Protoc (2007) 0.98
Differences in animal housing facilities and diet may affect study outcomes-a plea for inclusion of such information in publications. DNA Repair (Amst) (2006) 0.97
Diesel exhaust particles cause increased levels of DNA deletions after transplacental exposure in mice. Mutat Res (2005) 0.96
Role of homologous recombination in carcinogenesis. Exp Mol Pathol (2003) 0.96
RAD51 mutants cause replication defects and chromosomal instability. Mol Cell Biol (2012) 0.91
Intestinal bacteria modify lymphoma incidence and latency by affecting systemic inflammatory state, oxidative stress, and leukocyte genotoxicity. Cancer Res (2013) 0.90
High throughput screening of small molecule libraries for modifiers of radiation responses. Int J Radiat Biol (2011) 0.90
Increases in oxidative stress in the progeny of X-irradiated cells. Radiat Res (2004) 0.90
N-acetyl cysteine protects against ionizing radiation-induced DNA damage but not against cell killing in yeast and mammals. Mutat Res (2009) 0.90
Pol3 is involved in nonhomologous end-joining in Saccharomyces cerevisiae. DNA Repair (Amst) (2008) 0.90
Transcriptome analysis of a rotenone model of parkinsonism reveals complex I-tied and -untied toxicity mechanisms common to neurodegenerative diseases. PLoS One (2012) 0.89
Developmental cell death in the liver and newborn lethality of Ku86 deficient mice suppressed by antioxidant N-acetyl-cysteine. DNA Repair (Amst) (2006) 0.88
Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae. Genetics (2003) 0.88
14-3-3 σ expression effects G2/M response to oxygen and correlates with ovarian cancer metastasis. PLoS One (2011) 0.88
Impaired DNA double strand break repair in cells from Nijmegen breakage syndrome patients. DNA Repair (Amst) (2005) 0.88
Intestinal inflammation induces genotoxicity to extraintestinal tissues and cell types in mice. Int J Cancer (2011) 0.87
Myelodysplastic syndrome: an inability to appropriately respond to damaged DNA? Exp Hematol (2013) 0.87
Pathway Distiller - multisource biological pathway consolidation. BMC Genomics (2012) 0.86
Mice heterozygous for CREB binding protein are hypersensitive to γ-radiation and invariably develop myelodysplastic/myeloproliferative neoplasm. Exp Hematol (2011) 0.86
Adaptive response to gamma radiation in mammalian cells proficient and deficient in components of nucleotide excision repair. Radiat Res (2007) 0.84
Genomic instability in mice is greater in Fanconi anemia caused by deficiency of Fancd2 than Fancg. Cancer Res (2010) 0.84
Effects of antioxidants on cancer prevention and neuromotor performance in Atm deficient mice. Food Chem Toxicol (2007) 0.84
In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol Biol (2004) 0.84
Small-animal PET/CT for monitoring the development and response to chemotherapy of thymic lymphoma in Trp53-/- mice. J Nucl Med (2010) 0.83
A conditional mouse model for measuring the frequency of homologous recombination events in vivo in the absence of essential genes. Mol Cell Biol (2011) 0.83
Analysis of striatal transcriptome in mice overexpressing human wild-type alpha-synuclein supports synaptic dysfunction and suggests mechanisms of neuroprotection for striatal neurons. Mol Neurodegener (2011) 0.83
Promoter-trapping in Saccharomyces cerevisiae by radiation-assisted fragment insertion. Nucleic Acids Res (2002) 0.82
Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice. Mutat Res (2008) 0.82
Mutant p53 disrupts role of ShcA protein in balancing Smad protein-dependent and -independent signaling activity of transforming growth factor-β (TGF-β). J Biol Chem (2011) 0.81
Experimental antioxidant therapy in ataxia telangiectasia. Clin Med Oncol (2008) 0.81
The role of tumour necrosis factor-α and tumour necrosis factor receptor signalling in inflammation-associated systemic genotoxicity. Mutagenesis (2011) 0.81
Ionizing radiation induces microhomology-mediated end joining in trans in yeast and mammalian cells. Radiat Res (2009) 0.81
Carcinogenic Cr(VI) and the nutritional supplement Cr(III) induce DNA deletions in yeast and mice. Cancer Res (2006) 0.80
Genetic toxicity assessment: employing the best science for human safety evaluation Part VII: Why not start with a single test: a transformational alternative to genotoxicity hazard and risk assessment. Toxicol Sci (2007) 0.80
A high G418-resistant neo(R) transgenic mouse and mouse embryonic fibroblast (MEF) feeder layers for cytotoxicity and gene targeting in vivo and in vitro. Drug Chem Toxicol (2011) 0.80
Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Exp Hematol (2011) 0.80
IL-13 overexpression in mouse lungs triggers systemic genotoxicity in peripheral blood. Mutat Res (2014) 0.80
Mouse models for induced genetic instability at endogenous loci. Oncogene (2003) 0.80
Intestinal microbiome and lymphoma development. Cancer J (2014) 0.79
Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae. Mol Genet Genomics (2010) 0.79
More damaging than we think: systemic effects of intestinal inflammation. Cell Cycle (2009) 0.79
Yeast DEL assay detects clastogens. Mutat Res (2005) 0.79
Detecting carcinogens with the yeast DEL assay. Methods Mol Biol (2004) 0.79
9,10-Phenanthrenequinone induces DNA deletions and forward mutations via oxidative mechanisms in the yeast Saccharomyces cerevisiae. Toxicol In Vitro (2007) 0.78
Ku86 deficiency leads to reduced intrachromosomal homologous recombination in vivo in mice. DNA Repair (Amst) (2004) 0.78
2-Dodecylcyclobutanone does not induce mutations in the Salmonella mutagenicity test or intrachromosomal recombination in Saccharomyces cerevisiae. J Food Prot (2004) 0.78
Development of a microtiter plate version of the yeast DEL assay amenable to high-throughput toxicity screening of chemical libraries. Mutat Res (2007) 0.78
Intracellular and extracellular factors influencing Cr(VI) and Cr(III) genotoxicity. Environ Mol Mutagen (2011) 0.77
Intestinal microbiota reduces genotoxic endpoints induced by high-energy protons. Radiat Res (2014) 0.77
Heat-induced phosphorylation of NBS1 in human skin fibroblast cells. J Cell Biochem (2006) 0.77
Effects of side-stream tobacco smoke and smoke extract on glutathione- and oxidative DNA damage repair-deficient mice and blood cells. Mutat Res (2013) 0.77
Cell cycle dependence of ionizing radiation-induced DNA deletions and antioxidant radioprotection in Saccharomyces cerevisiae. Radiat Res (2010) 0.77
Radiation-induced myeloid leukemia in murine models. Hum Genomics (2014) 0.77
Rad1, rad10 and rad52 mutations reduce the increase of microhomology length during radiation-induced microhomology-mediated illegitimate recombination in saccharomyces cerevisiae. Radiat Res (2009) 0.77
Induction of homologous recombination following in utero exposure to DNA-damaging agents. DNA Repair (Amst) (2013) 0.76
Effect of benzene and its closed ring metabolites on intrachromosomal recombination in Saccharomyces cerevisiae. Mutat Res (2005) 0.76
Effect of rad50 mutation on illegitimate recombination in Saccharomyces cerevisiae. Mol Genet Genomics (2011) 0.76
Yeast DEL assay detects protection against radiation-induced cytotoxicity and genotoxicity: adaptation of a microtiter plate version. Radiat Res (2010) 0.76
The pol3-t hyperrecombination phenotype and DNA damage-induced recombination in Saccharomyces cerevisiae is RAD50 dependent. J Biomed Biotechnol (2009) 0.76
Nucleotide excision repair deficiency causes elevated levels of chromosome gain in Saccharomyces cerevisiae. DNA Repair (Amst) (2004) 0.76
Biological aspects of dichlorofluorescein measurement of cellular reactive oxygen species. Radiat Res (2008) 0.75
Mouse WRN Helicase Domain Is Not Required for Spontaneous Homologous Recombination-Mediated DNA Deletion. J Nucleic Acids (2010) 0.75
HNO induces DNA deletions in the yeast S. cerevisiae. Mutat Res (2007) 0.75
Mutagen X and chlorinated tap water are recombinagenic in yeast. Mutat Res (2004) 0.75
Mouse models for radiation-induced cancers. Mutagenesis (2016) 0.75
Effects of 1 GeV/nucleon ⁵⁶Fe particles on longevity, carcinogenesis and neuromotor ability in Atm-deficient mice. Radiat Res (2010) 0.75
Point-source irradiation with eccentric rotation causes inhomogeneous dose distribution. Radiat Res (2006) 0.75