Published in BMC Biol on June 11, 2009
Genetic manipulation of genes and cells in the nervous system of the fruit fly. Neuron (2011) 2.54
Sestrins orchestrate cellular metabolism to attenuate aging. Cell Metab (2013) 1.58
Mutations and quantitative genetic variation: lessons from Drosophila. Philos Trans R Soc Lond B Biol Sci (2010) 1.36
ppk23-Dependent chemosensory functions contribute to courtship behavior in Drosophila melanogaster. PLoS Genet (2012) 1.27
Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proc Natl Acad Sci U S A (2012) 1.08
Complex genetic architecture of Drosophila aggressive behavior. Proc Natl Acad Sci U S A (2011) 1.04
Tissue-specific regulation of chromatin insulator function. PLoS Genet (2012) 1.03
Unravelling the neurophysiological basis of aggression in a fish model. BMC Genomics (2010) 0.96
Design of RNA splicing analysis null models for post hoc filtering of Drosophila head RNA-Seq data with the splicing analysis kit (Spanki). BMC Bioinformatics (2013) 0.92
Genetics and neurobiology of aggression in Drosophila. Fly (Austin) (2012) 0.91
Multigenic natural variation underlies Caenorhabditis elegans olfactory preference for the bacterial pathogen Serratia marcescens. G3 (Bethesda) (2014) 0.90
The decision to fight or flee - insights into underlying mechanism in crickets. Front Neurosci (2012) 0.90
Transcriptome profiling of sexual maturation and mating in the Mediterranean fruit fly, Ceratitis capitata. PLoS One (2012) 0.88
Smaller, scale-free gene networks increase quantitative trait heritability and result in faster population recovery. PLoS One (2011) 0.85
Genetics and genomics of alcohol sensitivity. Mol Genet Genomics (2014) 0.83
Transcriptional networks for alcohol sensitivity in Drosophila melanogaster. Genetics (2011) 0.82
Genetic architecture of natural variation in Drosophila melanogaster aggressive behavior. Proc Natl Acad Sci U S A (2015) 0.82
Genetic architecture of olfactory behavior in Drosophila melanogaster: differences and similarities across development. Behav Genet (2013) 0.80
A genome-wide analysis reveals that the Drosophila transcription factor Lola promotes axon growth in part by suppressing expression of the actin nucleation factor Spire. Neural Dev (2011) 0.80
Identification of Drosophila Mutants Affecting Defense to an Entomopathogenic Fungus. Sci Rep (2015) 0.76
The genetic basis of natural variation in mushroom body size in Drosophila melanogaster. Nat Commun (2015) 0.76
Natural Genetic Variation and Candidate Genes for Morphological Traits in Drosophila melanogaster. PLoS One (2016) 0.75
A screen for genes expressed in the olfactory organs of Drosophila melanogaster identifies genes involved in olfactory behaviour. PLoS One (2012) 0.75
Dissecting the Genetic Architecture of Behavior in Drosophila melanogaster. Curr Opin Behav Sci (2015) 0.75
The complex genetic basis of simple behavior. J Biol (2009) 0.75
A Hidden Markov Model Approach for Simultaneously Estimating Local Ancestry and Admixture Time Using Next Generation Sequence Data in Samples of Arbitrary Ploidy. PLoS Genet (2017) 0.75
Axon Branch-Specific Semaphorin-1a Signaling in Drosophila Mushroom Body Development. Front Cell Neurosci (2016) 0.75
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods (2001) 414.27
DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol (2003) 84.79
A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback. Chromosoma (1989) 16.41
Using FlyAtlas to identify better Drosophila melanogaster models of human disease. Nat Genet (2007) 12.62
The BDGP gene disruption project: single transposon insertions associated with 40% of Drosophila genes. Genetics (2004) 8.40
FlyBase: integration and improvements to query tools. Nucleic Acids Res (2007) 5.14
The staufen/pumilio pathway is involved in Drosophila long-term memory. Curr Biol (2003) 4.82
Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. Genetics (1993) 3.75
BABELOMICS: a systems biology perspective in the functional annotation of genome-scale experiments. Nucleic Acids Res (2006) 3.62
Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait. Nat Genet (2002) 3.53
Specificities of heparan sulphate proteoglycans in developmental processes. Nature (2000) 3.46
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets. PLoS Biol (2004) 3.39
Behavioural abnormalities in male mice lacking neuronal nitric oxide synthase. Nature (1995) 3.15
Terminal cytokinesis events uncovered after an RNAi screen. Curr Biol (2004) 2.99
Octopamine in male aggression of Drosophila. Curr Biol (2008) 2.89
Branching morphogenesis of the Drosophila tracheal system. Annu Rev Cell Dev Biol (2003) 2.50
Serotonin and neuropeptide F have opposite modulatory effects on fly aggression. Nat Genet (2007) 2.48
Effects of single P-element insertions on bristle number and viability in Drosophila melanogaster. Genetics (1996) 2.40
Molecular analysis of flies selected for aggressive behavior. Nat Genet (2006) 2.29
Quantitative genomics of aggressive behavior in Drosophila melanogaster. PLoS Genet (2006) 2.17
Identification of Drosophila gene products required for phagocytosis of Candida albicans. PLoS Biol (2005) 2.09
Effects of single P-element insertions on olfactory behavior in Drosophila melanogaster. Genetics (1996) 1.98
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics (2006) 1.88
The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nat Genet (2003) 1.85
fruitless regulates aggression and dominance in Drosophila. Nat Neurosci (2006) 1.78
Quantitative trait loci affecting starvation resistance in Drosophila melanogaster. Genetics (2004) 1.76
Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Curr Biol (2003) 1.76
Genetics and genomics of Drosophila mating behavior. Proc Natl Acad Sci U S A (2005) 1.74
Genetic evidence that heparin-like glycosaminoglycans are involved in wingless signaling. Development (1997) 1.74
A role for actin dynamics in individualization during spermatogenesis in Drosophila melanogaster. Development (2003) 1.65
Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biol (2007) 1.64
Modulation of Drosophila male behavioral choice. Proc Natl Acad Sci U S A (2007) 1.63
Molecular basis of aggression. Trends Neurosci (2001) 1.59
Drosophila as a new model organism for the neurobiology of aggression? J Exp Biol (2002) 1.53
Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A (2008) 1.51
Brain monoamine oxidase A activity predicts trait aggression. J Neurosci (2008) 1.51
Sleep and wakefulness modulate gene expression in Drosophila. J Neurochem (2005) 1.50
Mutations affecting the development of the peripheral nervous system in Drosophila: a molecular screen for novel proteins. Genetics (2000) 1.49
X-linked borderline mental retardation with prominent behavioral disturbance: phenotype, genetic localization, and evidence for disturbed monoamine metabolism. Am J Hum Genet (1993) 1.48
A newly uncovered phenotype associated with the fruitless gene of Drosophila melanogaster: aggression-like head interactions between mutant males. Behav Genet (2000) 1.44
Specific subgroups of FruM neurons control sexually dimorphic patterns of aggression in Drosophila melanogaster. Proc Natl Acad Sci U S A (2007) 1.43
Defects in glucuronate biosynthesis disrupt Wingless signaling in Drosophila. Development (1997) 1.33
Serotonin, social status and aggression. Curr Opin Neurobiol (1997) 1.32
Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biol (2007) 1.27
Epistatic interactions between smell-impaired loci in Drosophila melanogaster. Genetics (1998) 1.26
Aggression and anger-related traits associated with a polymorphism of the tryptophan hydroxylase gene. Biol Psychiatry (1999) 1.25
Heparan sulfate proteoglycan modulation of developmental signaling in Drosophila. Biochim Biophys Acta (2002) 1.23
Escalated aggressive behavior: dopamine, serotonin and GABA. Eur J Pharmacol (2005) 1.23
Transcriptional response to alcohol exposure in Drosophila melanogaster. Genome Biol (2006) 1.21
Differential expression of the adhesion molecule Echinoid drives epithelial morphogenesis in Drosophila. Development (2006) 1.19
Influence of beta-alanine on mating and territorialism in Drosophila melanogaster. Behav Genet (1978) 1.19
Alternative 5C actin transcripts are localized in different patterns during Drosophila embryogenesis. Dev Biol (1989) 1.17
Serotonin and aggressive motivation in crustaceans: altering the decision to retreat. Proc Natl Acad Sci U S A (1997) 1.14
Neurosteroids, GABAA receptors, and escalated aggressive behavior. Horm Behav (2003) 1.14
Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nat Genet (2006) 1.10
Quantitative genetic analysis of sleep in Drosophila melanogaster. Genetics (2008) 1.09
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics (2009) 1.08
Behavioral profiling of NPY in aggression and neuropsychiatric diseases. Peptides (2006) 1.01
The cell adhesion molecule Echinoid defines a new pathway that antagonizes the Drosophila EGF receptor signaling pathway. Development (2001) 1.00
The helix-loop-helix extramacrochaetae protein is required for proper specification of many cell types in the Drosophila embryo. Development (1994) 1.00
A genomic analysis of membrane trafficking and neurotransmitter release in Drosophila. J Cell Biol (2000) 0.99
Transcripts of individual Drosophila actin genes are differentially distributed during embryogenesis. Dev Genet (1990) 0.99
Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. Genetics (2008) 0.98
Altered gene expression in mice selected for high maternal aggression. Genes Brain Behav (2006) 0.95
Echinoid mutants exhibit neurogenic phenotypes and show synergistic interactions with the Notch signaling pathway. Development (2003) 0.95
Catecholaminergic involvement in the control of aggression: hormones, the peripheral sympathetic, and central noradrenergic systems. Neurosci Biobehav Rev (1998) 0.92
Association of aggressive behavior in Korean male schizophrenic patients with polymorphisms in the serotonin transporter promoter and catecholamine-O-methyltransferase genes. Psychiatry Res (2004) 0.86
Y1 receptors regulate aggressive behavior by modulating serotonin pathways. Proc Natl Acad Sci U S A (2004) 0.86
Geographic variation in the territorial success of Drosophila melanogaster males. Behav Genet (1989) 0.84
NOS-I and -III gene variants are differentially associated with facets of suicidal behavior and aggression-related traits. Am J Med Genet B Neuropsychiatr Genet (2008) 0.82
Genetic analyses of essential genes in cytological region 61D1-2 to 61F1-2 of Drosophila melanogaster. Mol Genet Genomics (2002) 0.77
Finding the missing heritability of complex diseases. Nature (2009) 67.95
The Drosophila melanogaster Genetic Reference Panel. Nature (2012) 7.94
Systems genetics of complex traits in Drosophila melanogaster. Nat Genet (2009) 5.41
Genetic architecture of quantitative traits in mice, flies, and humans. Genome Res (2009) 4.62
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. Nat Genet (2006) 3.04
Using whole-genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster. PLoS Genet (2012) 2.90
Does evolutionary theory need a rethink? Nature (2014) 2.82
Epistasis dominates the genetic architecture of Drosophila quantitative traits. Proc Natl Acad Sci U S A (2012) 2.59
Dopa decarboxylase (Ddc) affects variation in Drosophila longevity. Nat Genet (2003) 2.56
Speed-mapping quantitative trait loci using microarrays. Nat Methods (2007) 2.26
Quantitative genomics of aggressive behavior in Drosophila melanogaster. PLoS Genet (2006) 2.17
Genotype-environment interactions at quantitative trait loci affecting inflorescence development in Arabidopsis thaliana. Genetics (2003) 1.92
Dynamic genetic interactions determine odor-guided behavior in Drosophila melanogaster. Genetics (2006) 1.88
The genetic architecture of odor-guided behavior in Drosophila: epistasis and the transcriptome. Nat Genet (2003) 1.85
Quantitative trait loci for inflorescence development in Arabidopsis thaliana. Genetics (2002) 1.84
Quantitative trait loci affecting starvation resistance in Drosophila melanogaster. Genetics (2004) 1.76
Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development. Curr Biol (2003) 1.76
Quantitative trait loci affecting natural variation in Drosophila longevity. Mech Ageing Dev (2004) 1.75
Quantitative genetic analyses of complex behaviours in Drosophila. Nat Rev Genet (2004) 1.67
Quantitative genomics of locomotor behavior in Drosophila melanogaster. Genome Biol (2007) 1.64
Novel loci control variation in reproductive timing in Arabidopsis thaliana in natural environments. Genetics (2002) 1.63
Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep. Nat Genet (2009) 1.59
miRNA genes and the brain: implications for psychiatric disorders. Hum Mutat (2010) 1.55
Aberrant lysosomal carbohydrate storage accompanies endocytic defects and neurodegeneration in Drosophila benchwarmer. J Cell Biol (2005) 1.52
Neurogenetic networks for startle-induced locomotion in Drosophila melanogaster. Proc Natl Acad Sci U S A (2008) 1.51
Phenotypic variation and natural selection at catsup, a pleiotropic quantitative trait gene in Drosophila. Curr Biol (2006) 1.49
hairy: A quantitative trait locus for drosophila sensory bristle number. Genetics (2002) 1.48
Heterogeneous selection at specific loci in natural environments in Arabidopsis thaliana. Genetics (2003) 1.44
The genetic architecture of Drosophila sensory bristle number. Genetics (2002) 1.41
Antitoxin treatment for liver abscess caused by Clostridium perfringens. Clin Mol Hepatol (2013) 1.39
Quantitative genomics of starvation stress resistance in Drosophila. Genome Biol (2005) 1.37
Genomic variation and its impact on gene expression in Drosophila melanogaster. PLoS Genet (2012) 1.31
Corynebacterium ulcerans 0102 carries the gene encoding diphtheria toxin on a prophage different from the C. diphtheriae NCTC 13129 prophage. BMC Microbiol (2012) 1.30
Cephalopod Hox genes and the origin of morphological novelties. Nature (2003) 1.29
The quantitative genetic basis of male mating behavior in Drosophila melanogaster. Genetics (2004) 1.28
Phenotypic and transcriptional response to selection for alcohol sensitivity in Drosophila melanogaster. Genome Biol (2007) 1.27
Quantitative trait loci for locomotor behavior in Drosophila melanogaster. Genetics (2006) 1.26
Phenotypic plasticity of the Drosophila transcriptome. PLoS Genet (2012) 1.26
Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping. Mech Ageing Dev (2006) 1.25
Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy. Bioessays (2009) 1.23
Surveillance of the clinical use of mamushi (Gloydius blomhoffii) antivenom in tertiary care centers in Japan. Jpn J Infect Dis (2011) 1.21
Dominant mutations in the tyrosyl-tRNA synthetase gene recapitulate in Drosophila features of human Charcot-Marie-Tooth neuropathy. Proc Natl Acad Sci U S A (2009) 1.21
Transcriptional response to alcohol exposure in Drosophila melanogaster. Genome Biol (2006) 1.21
Automated protein-DNA interaction screening of Drosophila regulatory elements. Nat Methods (2011) 1.21
Vanaso is a candidate quantitative trait gene for Drosophila olfactory behavior. Genetics (2002) 1.20
Plasticity of the chemoreceptor repertoire in Drosophila melanogaster. PLoS Genet (2009) 1.18
Quantitative trait loci for sexual isolation between Drosophila simulans and D. mauritiana. Genetics (2004) 1.18
Quantitative trait loci with age-specific effects on fecundity in Drosophila melanogaster. Genetics (2005) 1.17
Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila. Genetics (2007) 1.17
Quantitative trait loci affecting the difference in pigmentation between Drosophila yakuba and D. santomea. Genetics (2005) 1.16
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PLoS One (2012) 1.14
Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. PLoS Genet (2010) 1.14
The DSC1 channel, encoded by the smi60E locus, contributes to odor-guided behavior in Drosophila melanogaster. Genetics (2002) 1.13
Genome-wide association study of sleep in Drosophila melanogaster. BMC Genomics (2013) 1.11
Phenotypic plasticity and genotype by environment interaction for olfactory behavior in Drosophila melanogaster. Genetics (2008) 1.11
Pleiotropic fitness effects of the Tre1-Gr5a region in Drosophila melanogaster. Nat Genet (2006) 1.10
No evidence for an association between common nonsynonymous polymorphisms in delta and bristle number variation in natural and laboratory populations of Drosophila melanogaster. Genetics (2004) 1.10
The complex genetic architecture of Drosophila life span. Exp Aging Res (2002) 1.09
The genetic basis of postzygotic reproductive isolation between Drosophila santomea and D. yakuba due to hybrid male sterility. Genetics (2006) 1.09
Quantitative trait loci for aggressive behavior in Drosophila melanogaster. Genetics (2009) 1.08
Analysis of natural variation reveals neurogenetic networks for Drosophila olfactory behavior. Proc Natl Acad Sci U S A (2012) 1.08
AMP-activated protein kinase (AMPK) molecular crossroad for metabolic control and survival of neurons. Neuroscientist (2009) 1.08
Genome-wide association for sensitivity to chronic oxidative stress in Drosophila melanogaster. PLoS One (2012) 1.07
Overexpression of myocilin in the Drosophila eye activates the unfolded protein response: implications for glaucoma. PLoS One (2009) 1.06
Complex genetic architecture of Drosophila aggressive behavior. Proc Natl Acad Sci U S A (2011) 1.04
Natural variation, functional pleiotropy and transcriptional contexts of odorant binding protein genes in Drosophila melanogaster. Genetics (2010) 1.02
Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes. Hum Mol Genet (2013) 1.02
A transcriptional network associated with natural variation in Drosophila aggressive behavior. Genome Biol (2009) 1.02
Complementing complexity. Nat Genet (2004) 1.02
Understanding the neurogenetics of sleep: progress from Drosophila. Trends Genet (2009) 1.02
Enabling population and quantitative genomics. Genet Res (2002) 1.01
Genetics of aggression. Annu Rev Genet (2012) 1.00
Conserved cis-regulatory modules mediate complex neural expression patterns of the eyeless gene in the Drosophila brain. Mech Dev (2003) 1.00
The future of model organisms in human disease research. Nat Rev Genet (2011) 1.00
Alcohol sensitivity in Drosophila: translational potential of systems genetics. Genetics (2009) 0.99
Multifunctional interleukin-1beta promotes metastasis of human lung cancer cells in SCID mice via enhanced expression of adhesion-, invasion- and angiogenesis-related molecules. Cancer Sci (2003) 0.98
Drosophila alicorn is a neuronal maintenance factor protecting against activity-induced retinal degeneration. J Neurosci (2008) 0.98
Pinocchio, a novel protein expressed in the antenna, contributes to olfactory behavior in Drosophila melanogaster. J Neurobiol (2005) 0.98
Pleiotropic effects of Drosophila neuralized on complex behaviors and brain structure. Genetics (2008) 0.98
Natural variation in odorant recognition among odorant-binding proteins in Drosophila melanogaster. Genetics (2009) 0.97
Shuttle craft: a candidate quantitative trait gene for Drosophila lifespan. Aging Cell (2004) 0.96
The genetic basis of prezygotic reproductive isolation between Drosophila santomea and D. yakuba due to mating preference. Genetics (2006) 0.96
Odorant receptor polymorphisms and natural variation in olfactory behavior in Drosophila melanogaster. Genetics (2010) 0.96
Clinical efficacy of antivenom and cepharanthine for the treatment of Mamushi (Gloydius blomhoffii) bites in tertiary care centers in Japan. Jpn J Infect Dis (2013) 0.96
Conserved role for the Drosophila Pax6 homolog Eyeless in differentiation and function of insulin-producing neurons. Proc Natl Acad Sci U S A (2008) 0.95
Association of single-nucleotide polymorphisms at the Delta locus with genotype by environment interaction for sensory bristle number in drosophila Melanogaster. Genet Res (2002) 0.95
The genetic basis of alcoholism: multiple phenotypes, many genes, complex networks. Genome Biol (2012) 0.93
The early developmental gene Semaphorin 5c contributes to olfactory behavior in adult Drosophila. Genetics (2007) 0.93