David Wallach

Author PubWeight™ 47.39‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature 2003 6.11
2 The CD95 receptor: apoptosis revisited. Cell 2007 3.13
3 Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol 2004 3.09
4 Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 2012 2.58
5 RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity 2011 2.29
6 Hsp90 recognizes a common surface on client kinases. J Biol Chem 2006 2.12
7 Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep 2012 2.06
8 Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity 2004 1.99
9 Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J Immunol 2008 1.90
10 Caspase-8 is involved in neovascularization-promoting progenitor cell functions. Arterioscler Thromb Vasc Biol 2009 1.70
11 Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med 2009 1.69
12 Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases. J Exp Med 2004 1.67
13 Intraoperative airway obstruction related to tracheostomy tube malposition in a patient with achondroplasia and Jeune's syndrome. Middle East J Anaesthesiol 2010 1.44
14 Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. Cancer Res 2006 1.37
15 Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene 2003 1.28
16 Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology 2007 1.15
17 Hijacking of host cell IKK signalosomes by the transforming parasite Theileria. Science 2002 1.13
18 Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol Cell Biol 2006 1.12
19 NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. J Immunol 2006 1.10
20 Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med 2007 1.07
21 Transcription-controlled gene therapy against tumor angiogenesis. J Clin Invest 2004 0.94
22 Dominant negative MORT1/FADD rescues mice from CD95 and TNF-induced liver failure. Hepatology 2003 0.93
23 If the prophet does not come to the mountain: dynamics of signaling complexes in NF-kappaB activation. Mol Cell 2006 0.91
24 Proteasome-mediated proteolysis of the interleukin-10 receptor is important for signal downregulation. J Interferon Cytokine Res 2006 0.85
25 Cell-autonomous and non-cell-autonomous functions of caspase-8. Cytokine Growth Factor Rev 2008 0.81
26 MORT1/FADD is involved in liver regeneration. World J Gastroenterol 2005 0.80
27 Self-termination of the terminator. Nat Immunol 2008 0.79
28 Anti-inflammatory functions of caspase-8. Adv Exp Med Biol 2011 0.76
29 Probing cell death by chemical screening. Nat Chem Biol 2005 0.75
30 Up the down staircase. Nat Immunol 2002 0.75
31 Purification of TNF binding proteins. Methods Mol Med 2004 0.75