Published in Cytokine Growth Factor Rev on June 16, 2008
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med (2009) 1.69
mda-7/IL-24: a unique member of the IL-10 gene family promoting cancer-targeted toxicity. Cytokine Growth Factor Rev (2010) 1.30
Viral modulation of programmed necrosis. Curr Opin Virol (2013) 1.20
True grit: programmed necrosis in antiviral host defense, inflammation, and immunogenicity. J Immunol (2014) 0.99
Neuronal deletion of caspase 8 protects against brain injury in mouse models of controlled cortical impact and kainic acid-induced excitotoxicity. PLoS One (2011) 0.91
NF-kappaB functions as a tumour promoter in inflammation-associated cancer. Nature (2004) 15.14
VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells. Cell (2006) 9.32
The tumour suppressor CYLD negatively regulates NF-kappaB signalling by deubiquitination. Nature (2003) 6.11
Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood (2004) 4.04
The H19 non-coding RNA is essential for human tumor growth. PLoS One (2007) 3.75
The CD95 receptor: apoptosis revisited. Cell (2007) 3.13
Caspase-8 serves both apoptotic and nonapoptotic roles. J Immunol (2004) 3.09
Role of high expression levels of CXCR4 in tumor growth, vascularization, and metastasis. FASEB J (2004) 2.94
Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy. EMBO J (2002) 2.74
Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity (2012) 2.58
RIG-I RNA helicase activation of IRF3 transcription factor is negatively regulated by caspase-8-mediated cleavage of the RIP1 protein. Immunity (2011) 2.29
Hsp90 recognizes a common surface on client kinases. J Biol Chem (2006) 2.12
Monoclonal antibody HCV-AbXTL68 in patients undergoing liver transplantation for HCV: results of a phase 2 randomized study. Liver Transpl (2006) 2.12
Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep (2012) 2.06
Receptor-specific signaling for both the alternative and the canonical NF-kappaB activation pathways by NF-kappaB-inducing kinase. Immunity (2004) 1.99
Mutation of a self-processing site in caspase-8 compromises its apoptotic but not its nonapoptotic functions in bacterial artificial chromosome-transgenic mice. J Immunol (2008) 1.90
Phase I/II trial of intravenous NDV-HUJ oncolytic virus in recurrent glioblastoma multiforme. Mol Ther (2005) 1.85
Highly upregulated in liver cancer noncoding RNA is overexpressed in hepatic colorectal metastasis. Eur J Gastroenterol Hepatol (2009) 1.85
Small interfering RNA inhibits hepatitis B virus replication in mice. Mol Ther (2003) 1.76
Caspase-8 is involved in neovascularization-promoting progenitor cell functions. Arterioscler Thromb Vasc Biol (2009) 1.70
Caspase-8 deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J Exp Med (2009) 1.69
Stable genetic modification of human embryonic stem cells by lentiviral vectors. Mol Ther (2003) 1.68
Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases. J Exp Med (2004) 1.67
MicroRNA expression patterns and function in endodermal differentiation of human embryonic stem cells. PLoS One (2008) 1.56
IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol (2008) 1.48
Cell surface expression and secretion of heparanase markedly promote tumor angiogenesis and metastasis. Proc Natl Acad Sci U S A (2002) 1.45
Intraoperative airway obstruction related to tracheostomy tube malposition in a patient with achondroplasia and Jeune's syndrome. Middle East J Anaesthesiol (2010) 1.44
Resuscitation with aged blood exacerbates liver injury in a hemorrhagic rat model. Crit Care Med (2013) 1.44
Heparanase promotes growth, angiogenesis and survival of primary breast tumors. Int J Cancer (2006) 1.42
In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli. Clin Exp Pharmacol Physiol (2013) 1.41
The oncofetal H19 RNA connection: hypoxia, p53 and cancer. Biochim Biophys Acta (2010) 1.41
Gene transfer to chicks using lentiviral vectors administered via the embryonic chorioallantoic membrane. PLoS One (2012) 1.40
Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions. Cancer Res (2006) 1.37
Comprehensive gene and microRNA expression profiling reveals a role for microRNAs in human liver development. PLoS One (2009) 1.37
Heparanase accelerates wound angiogenesis and wound healing in mouse and rat models. FASEB J (2005) 1.32
A pivotal role of cyclic AMP-responsive element binding protein in tumor progression. Cancer Res (2004) 1.29
Mutant p53 gain of function: repression of CD95(Fas/APO-1) gene expression by tumor-associated p53 mutants. Oncogene (2003) 1.28
Mutant KRAS is a druggable target for pancreatic cancer. Proc Natl Acad Sci U S A (2013) 1.26
Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks. Proc Natl Acad Sci U S A (2010) 1.26
Involvement of the CXCL12/CXCR4 pathway in the advanced liver disease that is associated with hepatitis C virus or hepatitis B virus. Eur J Immunol (2004) 1.20
IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs. J Immunol (2006) 1.19
A plant-derived recombinant human glucocerebrosidase enzyme--a preclinical and phase I investigation. PLoS One (2009) 1.19
Increased microRNA activity in human cancers. PLoS One (2009) 1.18
Involvement of the CXCL12/CXCR4 pathway in the recovery of skin following burns. J Invest Dermatol (2006) 1.17
Gene therapy platform for bone regeneration using an exogenously regulated, AAV-2-based gene expression system. Mol Ther (2004) 1.17
Multiple adaptive mechanisms to chronic liver disease revealed at early stages of liver carcinogenesis in the Mdr2-knockout mice. Cancer Res (2006) 1.16
Role of caspase-8 in hepatocyte response to infection and injury in mice. Hepatology (2007) 1.15
Chemokines in hepatitis C virus infection: pathogenesis, prognosis and therapeutics. Cytokine (2007) 1.14
Involvement of CXCR4 and IL-2 in the homing and retention of human NK and NK T cells to the bone marrow and spleen of NOD/SCID mice. Blood (2003) 1.13
Hijacking of host cell IKK signalosomes by the transforming parasite Theileria. Science (2002) 1.13
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9. Mol Cell Biol (2006) 1.12
NF-kappaB-inducing kinase is involved in the activation of the CD28 responsive element through phosphorylation of c-Rel and regulation of its transactivating activity. J Immunol (2006) 1.10
Lentiviral vectors harboring a dual-gene system allow high and homogeneous transgene expression in selected polyclonal human embryonic stem cells. Mol Ther (2006) 1.10
Femtosecond infrared laser-an efficient and safe in vivo gene delivery system for prolonged expression. Mol Ther (2003) 1.08
CD4+CXCR4highCD69+ T cells accumulate in lung adenocarcinoma. J Immunol (2006) 1.08
CXCR4 antagonist 4F-benzoyl-TN14003 inhibits leukemia and multiple myeloma tumor growth. Exp Hematol (2010) 1.07
Regulation of B cell homeostasis and activation by the tumor suppressor gene CYLD. J Exp Med (2007) 1.07
Interaction between CXCR4 and CCL20 pathways regulates tumor growth. PLoS One (2009) 1.07
IFN-gamma treatment at early stages of influenza virus infection protects mice from death in a NK cell-dependent manner. J Interferon Cytokine Res (2010) 1.07
Toll-like receptor 3 signaling attenuates liver regeneration. Hepatology (2009) 1.06
High-resolution wide-field imaging of perfused capillaries without the use of contrast agent. Clin Ophthalmol (2011) 1.04
A3 adenosine receptors and mitogen-activated protein kinases in lung injury following in vivo reperfusion. Crit Care (2006) 1.03
Pregnancy restores the regenerative capacity of the aged liver via activation of an mTORC1-controlled hyperplasia/hypertrophy switch. Genes Dev (2010) 1.00
Molecular mechanisms of liver carcinogenesis in the mdr2-knockout mice. Mol Cancer Res (2007) 0.99
The hepatitis C virus (HCV)-Trimera mouse: a model for evaluation of agents against HCV. J Infect Dis (2002) 0.99
Retinal blood flow velocity in patients with age-related macular degeneration. Curr Eye Res (2013) 0.99
TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. J Cell Biochem (2007) 0.98
Increased retinal blood flow velocity in patients with early diabetes mellitus. Retina (2012) 0.98
Enhanced unique pattern of hematopoietic cell mobilization induced by the CXCR4 antagonist 4F-benzoyl-TN14003. Stem Cells (2007) 0.97
Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer. Breast Cancer Res Treat (2013) 0.97
Molecular imaging of the skeleton: quantitative real-time bioluminescence monitoring gene expression in bone repair and development. J Bone Miner Res (2003) 0.96
Retinal blood flow velocity measured by retinal function imaging in retinitis pigmentosa. Graefes Arch Clin Exp Ophthalmol (2011) 0.95
HCV tumor promoting effect is dependent on host genetic background. PLoS One (2009) 0.95
Functional MR imaging during hypercapnia and hyperoxia: noninvasive tool for monitoring changes in liver perfusion and hemodynamics in a rat model. Radiology (2007) 0.94
Anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb extract on murine cell lines and OVA-induced airway inflammation. J Ethnopharmacol (2012) 0.94