Published in J Biol Chem on April 06, 2006
Structural determinants and mechanism of HIV-1 genome packaging. J Mol Biol (2011) 1.83
Visualizing transient low-populated structures of RNA. Nature (2012) 1.36
Physics-based de novo prediction of RNA 3D structures. J Phys Chem B (2011) 1.21
Resolving fast and slow motions in the internal loop containing stem-loop 1 of HIV-1 that are modulated by Mg2+ binding: role in the kissing-duplex structural transition. Nucleic Acids Res (2007) 1.06
Understanding the isomerization of the HIV-1 dimerization initiation domain by the nucleocapsid protein. J Mol Biol (2007) 0.97
Recognition modes of RNA tetraloops and tetraloop-like motifs by RNA-binding proteins. Wiley Interdiscip Rev RNA (2013) 0.94
Mechanistic studies of hairpin to duplex conversion for trinucleotide repeat sequences. J Biol Chem (2010) 0.89
Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding. Nucleic Acids Res (2007) 0.89
Structure and stability of RNA/RNA kissing complex: with application to HIV dimerization initiation signal. RNA (2011) 0.88
A proposal for a new HIV-1 DLS structural model. Nucleic Acids Res (2012) 0.86
Noncovalent probes for the investigation of structure and dynamics of protein-nucleic acid assemblies: the case of NC-mediated dimerization of genomic RNA in HIV-1. Biopolymers (2009) 0.86
Transduction of human immunodeficiency virus type 1 vectors lacking encapsidation and dimerization signals. J Virol (2007) 0.85
NMR detection of intermolecular interaction sites in the dimeric 5'-leader of the HIV-1 genome. Proc Natl Acad Sci U S A (2016) 0.81
Predicting structure and stability for RNA complexes with intermolecular loop-loop base-pairing. RNA (2014) 0.81
Efficient HIV-1 inhibition by a 16 nt-long RNA aptamer designed by combining in vitro selection and in silico optimisation strategies. Sci Rep (2014) 0.78
Binding characteristics of small molecules that mimic nucleocapsid protein-induced maturation of stem-loop 1 of HIV-1 RNA. Biochemistry (2010) 0.77
HIV-1 DIS stem loop forms an obligatory bent kissing intermediate in the dimerization pathway. Nucleic Acids Res (2014) 0.76
New Structure Sheds Light on Selective HIV-1 Genomic RNA Packaging. Viruses (2015) 0.76
Structural features of a 3' splice site in influenza a. Biochemistry (2015) 0.76
NMR Studies of the Structure and Function of the HIV-1 5'-Leader. Viruses (2016) 0.75
Structure-specific nucleic acid recognition by L-motifs and their diverse roles in expression and regulation of the genome. Biochim Biophys Acta (2015) 0.75
DOCK 6: combining techniques to model RNA-small molecule complexes. RNA (2009) 2.75
Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome. Mol Cell (2012) 2.54
cis-Acting packaging signals in the influenza virus PB1, PB2, and PA genomic RNA segments. J Virol (2005) 2.50
Method for determining molar concentrations of metabolites in complex solutions from two-dimensional 1H-13C NMR spectra. Anal Chem (2007) 2.46
Structural basis for cAMP-mediated allosteric control of the catabolite activator protein. Proc Natl Acad Sci U S A (2009) 2.39
Viral RNA is required for the association of APOBEC3G with human immunodeficiency virus type 1 nucleoprotein complexes. J Virol (2005) 2.29
Dynamics connect substrate recognition to catalysis in protein kinase A. Nat Chem Biol (2010) 1.95
Perspectives on NMR in drug discovery: a technique comes of age. Nat Rev Drug Discov (2008) 1.95
A universal telomerase RNA core structure includes structured motifs required for binding the telomerase reverse transcriptase protein. Proc Natl Acad Sci U S A (2004) 1.83
High-resolution iterative frequency identification for NMR as a general strategy for multidimensional data collection. J Am Chem Soc (2005) 1.79
A molecular switch underlies a human telomerase disease. Proc Natl Acad Sci U S A (2002) 1.79
Mutational analyses of packaging signals in influenza virus PA, PB1, and PB2 genomic RNA segments. J Virol (2007) 1.72
A viral RNA structural element alters host recognition of nonself RNA. Science (2014) 1.71
RNA helical packing in solution: NMR structure of a 30 kDa GAAA tetraloop-receptor complex. J Mol Biol (2005) 1.65
RNA structure and packaging signals in the 5' leader region of the human immunodeficiency virus type 1 genome. J Virol (2002) 1.60
Evidence for segment-nonspecific packaging of the influenza a virus genome. J Virol (2002) 1.51
Comprehensive structure-function analysis of the core domain of human telomerase RNA. Mol Cell Biol (2003) 1.49
Defective assembly of influenza A virus due to a mutation in the polymerase subunit PA. J Virol (2006) 1.45
Identification and functional characterization of 2 variant alleles of the telomerase RNA template gene (TERC) in a patient with dyskeratosis congenita. Blood (2005) 1.37
Structure and dynamics of the iron-sulfur cluster assembly scaffold protein IscU and its interaction with the cochaperone HscB. Biochemistry (2009) 1.36
Structural and biochemical insights into the dicing mechanism of mouse Dicer: a conserved lysine is critical for dsRNA cleavage. Proc Natl Acad Sci U S A (2008) 1.35
Functional characterization of telomerase RNA variants found in patients with hematologic disorders. Blood (2004) 1.33
Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. Chem Biol (2002) 1.30
Protein conformational dynamics in the mechanism of HIV-1 protease catalysis. Proc Natl Acad Sci U S A (2011) 1.25
Locally disordered conformer of the hamster prion protein: a crucial intermediate to PrPSc? Biochemistry (2002) 1.24
NMR-detected hydrogen exchange and molecular dynamics simulations provide structural insight into fibril formation of prion protein fragment 106-126. Proc Natl Acad Sci U S A (2003) 1.22
A role for a novel 'trans-pseudoknot' RNA-RNA interaction in the functional dimerization of human telomerase. Genes Dev (2003) 1.20
Structure of a construct of a human poly(C)-binding protein containing the first and second KH domains reveals insights into its regulatory mechanisms. J Biol Chem (2008) 1.20
Crystal structure of the first KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.7 A. J Biol Chem (2005) 1.19
Disordered form of the scaffold protein IscU is the substrate for iron-sulfur cluster assembly on cysteine desulfurase. Proc Natl Acad Sci U S A (2011) 1.17
NMR-based characterization of phenothiazines as a RNA binding scaffold. J Am Chem Soc (2004) 1.17
Robust, integrated computational control of NMR experiments to achieve optimal assignment by ADAPT-NMR. PLoS One (2012) 1.15
Solution structure of a late embryogenesis abundant protein (LEA14) from Arabidopsis thaliana, a cellular stress-related protein. Protein Sci (2005) 1.10
Solution structure of the iron-sulfur cluster cochaperone HscB and its binding surface for the iron-sulfur assembly scaffold protein IscU. Biochemistry (2008) 1.08
Solution structure of a consensus stem-loop D RNA domain that plays important roles in regulating translation and replication in enteroviruses and rhinoviruses. Biochemistry (2004) 1.08
Metamorphic protein IscU alternates conformations in the course of its role as the scaffold protein for iron-sulfur cluster biosynthesis and delivery. FEBS Lett (2013) 1.07
Structure of TAR RNA complexed with a Tat-TAR interaction nanomolar inhibitor that was identified by computational screening. Chem Biol (2002) 1.06
Bipartite signal for genomic RNA dimerization in Moloney murine leukemia virus. J Virol (2002) 1.05
Docking to RNA via root-mean-square-deviation-driven energy minimization with flexible ligands and flexible targets. J Chem Inf Model (2008) 1.04
PI3K inhibition in neonatal rat brain slices during and after hypoxia reduces phospho-Akt and increases cytosolic cytochrome c and apoptosis. Brain Res Mol Brain Res (2004) 1.02
Pyruvate improves recovery after PARP-1-associated energy failure induced by oxidative stress in neonatal rat cerebrocortical slices. J Cereb Blood Flow Metab (2006) 1.01
Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA. Chem Biol (2006) 1.01
Specialized Hsp70 chaperone (HscA) binds preferentially to the disordered form, whereas J-protein (HscB) binds preferentially to the structured form of the iron-sulfur cluster scaffold protein (IscU). J Biol Chem (2012) 1.01
Occidiofungin, a unique antifungal glycopeptide produced by a strain of Burkholderia contaminans. Biochemistry (2009) 1.01
Crystal structure of the third KH domain of human poly(C)-binding protein-2 in complex with a C-rich strand of human telomeric DNA at 1.6 A resolution. Nucleic Acids Res (2007) 0.99
Solution NMR of acetylcholine binding protein reveals agonist-mediated conformational change of the C-loop. Mol Pharmacol (2006) 0.99
Receptor tyrosine kinase inhibitors block multiple steps of influenza a virus replication. J Virol (2011) 0.99
Interaction of the histone mRNA hairpin with stem-loop binding protein (SLBP) and regulation of the SLBP-RNA complex by phosphorylation and proline isomerization. Biochemistry (2012) 0.98
Role of metal ions in the tetraloop-receptor complex as analyzed by NMR. RNA (2006) 0.98
Structure of the AML1-ETO eTAFH domain-HEB peptide complex and its contribution to AML1-ETO activity. Blood (2009) 0.98
The dynamic structure of thrombin in solution. Biophys J (2012) 0.98
Direct NMR detection of the binding of functional ligands to the human sweet receptor, a heterodimeric family 3 GPCR. J Am Chem Soc (2008) 0.97
Ligand-specific structural changes in the vitamin D receptor in solution. Biochemistry (2011) 0.96
Structure of the HIV-1 frameshift site RNA bound to a small molecule inhibitor of viral replication. ACS Chem Biol (2011) 0.96
Pseudoknot structures with conserved base triples in telomerase RNAs of ciliates. Nucleic Acids Res (2007) 0.96
Differences in the structure and dynamics of the apo- and palmitate-ligated forms of Aedes aegypti sterol carrier protein 2 (AeSCP-2). J Biol Chem (2010) 0.96
High-resolution NMR structure of an AT-rich DNA sequence. J Biomol NMR (2002) 0.96
Metamorphic protein IscU changes conformation by cis-trans isomerizations of two peptidyl-prolyl peptide bonds. Biochemistry (2012) 0.95
Three-dimensional structure and determinants of stability of the iron-sulfur cluster scaffold protein IscU from Escherichia coli. Biochemistry (2012) 0.94
Structural insight into the interaction of proteins containing NPF, DPF, and GPF motifs with the C-terminal EH-domain of EHD1. Protein Sci (2009) 0.93
Outcome-related metabolomic patterns from 1H/31P NMR after mild hypothermia treatments of oxygen-glucose deprivation in a neonatal brain slice model of asphyxia. J Cereb Blood Flow Metab (2010) 0.93
Extending the family of UNCG-like tetraloop motifs: NMR structure of a CACG tetraloop from coxsackievirus B3. Biochemistry (2003) 0.92
Discovery of ligands for a novel target, the human telomerase RNA, based on flexible-target virtual screening and NMR. J Med Chem (2008) 0.92
NMR structures of loop B RNAs from the stem-loop IV domain of the enterovirus internal ribosome entry site: a single C to U substitution drastically changes the shape and flexibility of RNA. Biochemistry (2004) 0.92
Slow conformational dynamics in the hamster prion protein. Biochemistry (2004) 0.92
In vivo monitoring of hepatic glutathione in anesthetized rats by 13C NMR. Magn Reson Med (2002) 0.91
Interactions between the human sweet-sensing T1R2-T1R3 receptor and sweeteners detected by saturation transfer difference NMR spectroscopy. Biochim Biophys Acta (2009) 0.91
Nucleocapsid protein-mediated maturation of dimer initiation complex of full-length SL1 stemloop of HIV-1: sequence effects and mechanism of RNA refolding. Nucleic Acids Res (2007) 0.89
Specific recognition of the C-rich strand of human telomeric DNA and the RNA template of human telomerase by the first KH domain of human poly(C)-binding protein-2. J Biol Chem (2004) 0.89
Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1. Protein Sci (2005) 0.89
Detecting ligand binding to a small RNA target via saturation transfer difference NMR experiments in D(2)O and H(2)O. J Am Chem Soc (2002) 0.88
Exogenous ethyl pyruvate versus pyruvate during metabolic recovery after oxidative stress in neonatal rat cerebrocortical slices. Anesthesiology (2007) 0.88
HIFI-C: a robust and fast method for determining NMR couplings from adaptive 3D to 2D projections. J Biomol NMR (2007) 0.88
1H nuclear magnetic resonance brain metabolomics in neonatal mice after hypoxia-ischemia distinguished normothermic recovery from mild hypothermia recoveries. Pediatr Res (2013) 0.87
Structural characterization of Hsp12, the heat shock protein from Saccharomyces cerevisiae, in aqueous solution where it is intrinsically disordered and in detergent micelles where it is locally α-helical. J Biol Chem (2011) 0.87
Structural basis for the catalytic mechanism of mammalian 25-kDa thiamine triphosphatase. J Biol Chem (2008) 0.86
Simultaneous detection and deconvolution of congested NMR spectra containing three isotopically labeled species. J Am Chem Soc (2008) 0.86
NMR method for measuring carbon-13 isotopic enrichment of metabolites in complex solutions. Anal Chem (2010) 0.86
Novel diagnostics of metabolic dysfunction detected in breath and plasma by selective isotope-assisted labeling. Metabolism (2012) 0.85
Receptor tyrosine kinase inhibitors that block replication of influenza a and other viruses. Antimicrob Agents Chemother (2011) 0.85
The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family. Acta Crystallogr D Biol Crystallogr (2013) 0.84
Structure-activity relationships of aminoglycoside-arginine conjugates that bind HIV-1 RNAs as determined by fluorescence and NMR spectroscopy. FEBS Lett (2004) 0.84
Discovery of ligands by a combination of computational and NMR-based screening: RNA as an example target. Methods Enzymol (2005) 0.83
Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists. ACS Chem Biol (2012) 0.83
Fast automated protein NMR data collection and assignment by ADAPT-NMR on Bruker spectrometers. J Magn Reson (2013) 0.83
Backbone NMR resonance assignment of the catalytic subunit of cAMP-dependent protein kinase A in complex with AMP-PNP. Biomol NMR Assign (2009) 0.82
A general NMR-based strategy for the in situ characterization of sugar-nucleotide-dependent biosynthetic pathways. Org Lett (2014) 0.82
RNA structural motifs that entail hydrogen bonds involving sugar-phosphate backbone atoms of RNA. New J Chem (2010) 0.82
Highly conserved RNA pseudoknots at the Gag-Pol junction of HIV-1 suggest a novel mechanism of -1 ribosomal frameshifting. RNA (2014) 0.82
Temperature-dependent conformational change affecting Tyr11 and sweetness loops of brazzein. Proteins (2013) 0.81
NMR structure of a gemcitabine-substituted model Okazaki fragment. Biochemistry (2002) 0.81
Resonance assignments for the two N-terminal RNA recognition motifs (RRM) of the S. cerevisiae pre-mRNA processing protein Prp24. J Biomol NMR (2006) 0.81
The cyclobutane dimers of 5-methylcytosine and their deamination products. Photochem Photobiol Sci (2004) 0.81
Structure and function of a fungal adhesin that binds heparin and mimics thrombospondin-1 by blocking T cell activation and effector function. PLoS Pathog (2013) 0.81