Published in N Engl J Med on September 02, 2004
Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343. J Clin Oncol (2013) 6.56
Breast cancer treatment of older women in integrated health care settings. J Clin Oncol (2006) 3.46
Outcome prediction for estrogen receptor-positive breast cancer based on postneoadjuvant endocrine therapy tumor characteristics. J Natl Cancer Inst (2008) 3.21
Assessing the impact of a cooperative group trial on breast cancer care in the medicare population. J Clin Oncol (2012) 3.07
Nomogram to predict the benefit of radiation for older patients with breast cancer treated with conservative surgery. J Clin Oncol (2012) 2.85
Breast cancer among the oldest old: tumor characteristics, treatment choices, and survival. J Clin Oncol (2010) 2.45
Benefit of adjuvant brachytherapy versus external beam radiation for early breast cancer: impact of patient stratification on breast preservation. Int J Radiat Oncol Biol Phys (2013) 2.30
Axillary dissection versus no axillary dissection in elderly patients with breast cancer and no palpable axillary nodes: results after 15 years of follow-up. Ann Surg Oncol (2010) 2.14
Impact of mammographic screening on the detection of good and poor prognosis breast cancers. Breast Cancer Res Treat (2011) 1.55
Underuse of breast cancer adjuvant treatment: patient knowledge, beliefs, and medical mistrust. J Clin Oncol (2009) 1.51
Senior adult oncology. J Natl Compr Canc Netw (2012) 1.20
Publicly funded clinical trials and the future of cancer care. Oncologist (2013) 1.15
Patterns and correlates of adjuvant radiotherapy receipt after lumpectomy and after mastectomy for breast cancer. J Clin Oncol (2010) 1.12
Undertreated breast cancer in the elderly. J Cancer Epidemiol (2013) 1.11
Accelerated partial breast irradiation: technically feasible but who will benefit? Breast Cancer Res (2005) 1.10
The impact of age on outcome in early-stage breast cancer. Semin Radiat Oncol (2011) 1.09
Age, comorbidity, and breast cancer severity: impact on receipt of definitive local therapy and rate of recurrence among older women with early-stage breast cancer. J Am Coll Surg (2011) 1.07
Biological, clinical, and psychosocial correlates at the interface of cancer and aging research. J Natl Cancer Inst (2012) 1.07
The adoption of new adjuvant radiation therapy modalities among Medicare beneficiaries with breast cancer: clinical correlates and cost implications. Int J Radiat Oncol Biol Phys (2012) 1.00
Modeling the effect of age in T1-2 breast cancer using the SEER database. BMC Cancer (2005) 0.95
Geriatric assessment in older patients with breast cancer. J Natl Compr Canc Netw (2009) 0.95
Prone accelerated partial breast irradiation after breast-conserving surgery: five-year results of 100 patients. Int J Radiat Oncol Biol Phys (2012) 0.95
Effectiveness of radiation for prevention of mastectomy in older breast cancer patients treated with conservative surgery. Cancer (2012) 0.94
Adjuvant therapy for women over age 65 with breast cancer. Dtsch Arztebl Int (2011) 0.92
Geriatric assessment in oncology practice. J Am Geriatr Soc (2009) 0.91
Patient, hospital, and neighborhood factors associated with treatment of early-stage breast cancer among Asian American women in California. Cancer Epidemiol Biomarkers Prev (2012) 0.90
Risk of decline in upper-body function and symptoms among older breast cancer patients. J Gen Intern Med (2006) 0.89
Breast cancer in elderly women (≥ 80 years): variation in standard of care? J Surg Oncol (2010) 0.89
Surgical treatment of early stage breast cancer in elderly: an international comparison. Breast Cancer Res Treat (2011) 0.89
External beam accelerated partial-breast irradiation using 32 gy in 8 twice-daily fractions: 5-year results of a prospective study. Int J Radiat Oncol Biol Phys (2012) 0.89
Guideline adherence for early breast cancer before and after introduction of the sentinel node biopsy. Br J Cancer (2005) 0.89
Variation in receipt of radiation therapy after breast-conserving surgery: assessing the impact of physicians and geographic regions. Med Care (2013) 0.89
Second malignancies in breast cancer patients following radiotherapy: a study in Florence, Italy. Breast Cancer Res (2011) 0.89
The impact of patient compliance with adjuvant radiotherapy: a comprehensive cohort study. Cancer Med (2013) 0.89
Radiotherapy issues in elderly breast cancer patients. Breast Care (Basel) (2012) 0.88
Clinical management of secondary angiosarcoma after breast conservation therapy. Rep Pract Oncol Radiother (2013) 0.87
Long-term clinical outcome of oestrogen receptor-positive operable primary breast cancer in older women: a large series from a single centre. Br J Cancer (2011) 0.86
TARGIT-E(lderly)--prospective phase II study of intraoperative radiotherapy (IORT) in elderly patients with small breast cancer. BMC Cancer (2012) 0.86
Does Life Expectancy Affect Treatment of Women Aged 80 and Older with Early Stage Breast Cancers? J Geriatr Oncol (2012) 0.86
Intraoperative Electron Radiotherapy (IOERT) as an Alternative to Standard Whole Breast Irradiation: Only for Low-Risk Subgroups? Breast Care (Basel) (2014) 0.85
Breast cancer in the elderly-Should it be treated differently? Rep Pract Oncol Radiother (2012) 0.85
Landmark trials affecting the surgical management of invasive breast cancer. Surg Clin North Am (2013) 0.85
Electrons for intraoperative radiotherapy in selected breast-cancer patients: late results of the Montpellier phase II trial. Radiat Oncol (2013) 0.84
Effect of socioeconomic status as measured by education level on survival in breast cancer clinical trials. Psychooncology (2011) 0.84
Examining the cost-effectiveness of radiation therapy among older women with favorable-risk breast cancer. J Natl Cancer Inst (2014) 0.84
Breast radiotherapy after lumpectomy--no longer always necessary. N Engl J Med (2004) 0.83
The impact of adjuvant radiotherapy on the survival of primary breast cancer patients: a retrospective multicenter cohort study of 8935 subjects. Ann Oncol (2014) 0.83
United States trends in the surgical treatment of primary breast cancer. World J Surg (2012) 0.83
Options in breast cancer local therapy: who gets what? World J Surg (2012) 0.83
For-profit hospital ownership status and use of brachytherapy after breast-conserving surgery. Surgery (2013) 0.82
Patterns of locoregional treatment for nonmetastatic breast cancer by patient and health system factors. Cancer (2014) 0.82
Adjuvant Endocrine Therapy in Patients with Ductal Carcinoma In Situ: A Population-Based Retrospective Analysis from 2005 to 2012 in the National Cancer Data Base. Ann Surg Oncol (2015) 0.82
Successful management of elderly breast cancer patients treated without radiotherapy. World J Surg Oncol (2007) 0.82
Current modalities of accelerated partial breast irradiation. Nat Rev Clin Oncol (2013) 0.82
Recent developments in breast-conserving surgery for breast cancer patients. Langenbecks Arch Surg (2008) 0.82
When are breast cancer patients old enough for the quitclaim of local control? Strahlenther Onkol (2012) 0.81
Population-based study of breast cancer in older women: prognostic factors of relative survival and predictors of treatment. BMC Cancer (2012) 0.81
Early-Stage Breast Cancer in the Elderly: Confronting an Old Clinical Problem. J Breast Cancer (2015) 0.80
Managing breast cancer in the older patient. Clin Adv Hematol Oncol (2013) 0.80
Thirty years of experience with mammography screening: a new approach to the diagnosis and treatment of breast cancer. Breast Cancer Res (2008) 0.80
Intraoperative radiotherapy in early stage breast cancer: potential indications and evidence to date. Br J Radiol (2015) 0.79
Critical appraisal training increases understanding and confidence and enhances the use of evidence in diverse categories of learners. Health Expect (2012) 0.79
Benefit of adjuvant radiotherapy after breast-conserving therapy among elderly women with T1-T2N0 estrogen receptor-negative breast cancer. Cancer (2016) 0.79
Evaluation of Sentinel Lymph Node Dose Distribution in 3D Conformal Radiotherapy Techniques in 67 pN0 Breast Cancer Patients. Int J Breast Cancer (2015) 0.79
The cycle of bias in health research: a framework and toolbox for critical appraisal training. Account Res (2013) 0.78
Older patients with breast cancer: is there bias in the treatment they receive? Ther Adv Med Oncol (2012) 0.78
The benefit of adjuvant radiotherapy after breast conserving surgery in older patients with low risk breast cancer- a meta-analysis of randomized trials. Radiat Oncol (2017) 0.77
Radiation therapy in early-stage invasive breast cancer. Indian J Surg Oncol (2011) 0.77
Conservative management of breast cancer in the elderly in a developing country. World J Surg Oncol (2007) 0.77
Breast cancer (non-metastatic). BMJ Clin Evid (2011) 0.77
Can patient comorbidities be included in clinical performance measures for radiation oncology? J Oncol Pract (2014) 0.77
Successful pregnancy after breast cancer therapy: dream or reality? Int Semin Surg Oncol (2009) 0.77
Surveillance Mammography in Older Patients With Breast Cancer-Can We Ever Stop?: A Review. JAMA Oncol (2016) 0.76
Breast cancer follow-up strategies in randomized phase III adjuvant clinical trials: a systematic review. J Exp Clin Cancer Res (2013) 0.76
Breast Cancer in the Elderly: Is MRI Helpful? Breast J (2015) 0.75
When cancer in older adults is undermanaged: the breast cancer story. J Am Geriatr Soc (2009) 0.75
Trends in Local Therapy Utilization and Cost for Early-Stage Breast Cancer in Older Women: Implications for Payment and Policy Reform. Int J Radiat Oncol Biol Phys (2016) 0.75
Early breast cancer in the older woman. Clin Geriatr Med (2011) 0.75
Preoperative Breast Magnetic Resonance Imaging and Contralateral Breast Cancer Occurrence Among Older Women With Breast Cancer. J Clin Oncol (2015) 0.75
Tomorrow's cancer treatments today: the first 50 years of the Cancer and Leukemia Group B. Semin Oncol (2008) 0.75
Optimal approach in early breast cancer: Radiation therapy. EJC Suppl (2013) 0.75
Information Needs of Older Women With Early-Stage Breast Cancer When Making Radiation Therapy Decisions. Int J Radiat Oncol Biol Phys (2017) 0.75
Adjuvant radiation use in older women with early-stage breast cancer at Johns Hopkins. Breast Cancer Res Treat (2016) 0.75
Locoregional Recurrence and Survival Rates after Breast-Conserving Surgery and Hormonal Therapy in 70-Year-Old or Older Patients with Stage I or IIA Breast Carcinoma. Breast Care (Basel) (2013) 0.75
How can we best respect patient autonomy in breast cancer treatment decisions? Breast Cancer Manag (2015) 0.75
The diffusion of docetaxel in patients with metastatic prostate cancer. J Natl Cancer Inst (2014) 0.75
Comparison of the Initial Loco-Regional Treatment Received for Early-Stage Breast Cancer between Elderly Women in Appalachia and a United States - Based Population: Good and Bad News. Global J Breast Cancer Res (2016) 0.75
Location Isn't Everything: Proximity, Hospital Characteristics, Choice of Hospital, and Disparities for Breast Cancer Surgery Patients. Health Serv Res (2016) 0.75
Accelerated partial breast irradiation compared with whole breast radiation therapy: a breast cancer cohort study measuring change in radiation side-effects severity and quality of life. Breast Cancer Res Treat (2017) 0.75
Optimal management of breast cancer in the elderly patient: current perspectives. Clin Interv Aging (2015) 0.75
Effect of radiotherapy on survival of women with locally excised ductal carcinoma in situ of the breast: a Surveillance, Epidemiology, and End Results population-based analysis. Onco Targets Ther (2015) 0.75
Utilization trend and regimens of hypofractionated whole breast radiation therapy in the United States. Breast Cancer Res Treat (2017) 0.75
Breast cancer (non-metastatic). BMJ Clin Evid (2007) 0.75
Do all patients require radiotherapy after breast-conserving surgery? Cancers (Basel) (2010) 0.75
Proportion and clinical outcomes of postoperative radiotherapy omission after breast-conserving surgery in women with breast cancer. J Breast Cancer (2015) 0.75
Adjuvant Endocrine Therapy in Breast Cancer: A Novel e-Health Approach in Optimizing Treatment for Seniors (OPTIMUM): A Two-Group Controlled Comparison Pilot Study. JMIR Res Protoc (2016) 0.75
Lumpectomy and tamoxifen alone without additional radiotherapy for women 70 years of age or older with estrogen receptor-positive breast cancer. Breast Cancer Res Treat (2005) 0.75
Accrual of Older Patients With Breast Cancer to Alliance Systemic Therapy Trials Over Time: Protocol A151527. J Clin Oncol (2016) 0.75
Function-preserving surgery for breast cancer. Int J Clin Oncol (2006) 0.75
Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer. N Engl J Med (2002) 24.87
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J Clin Oncol (2007) 14.29
A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer. N Engl J Med (2003) 13.81
Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer. J Clin Oncol (2003) 9.72
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59
Prognostic and predictive value of the 21-gene recurrence score assay in postmenopausal women with node-positive, oestrogen-receptor-positive breast cancer on chemotherapy: a retrospective analysis of a randomised trial. Lancet Oncol (2009) 9.39
HER2 and response to paclitaxel in node-positive breast cancer. N Engl J Med (2007) 9.34
Representational oligonucleotide microarray analysis: a high-resolution method to detect genome copy number variation. Genome Res (2003) 7.86
Risk-reducing salpingo-oophorectomy in women with a BRCA1 or BRCA2 mutation. N Engl J Med (2002) 7.84
American Society of Clinical Oncology identifies five key opportunities to improve care and reduce costs: the top five list for oncology. J Clin Oncol (2012) 7.16
Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781. J Clin Oncol (2008) 7.01
Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group. J Clin Oncol (2005) 6.98
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis. Cancer Res (2005) 6.93
American Society of Clinical Oncology guidance statement: the cost of cancer care. J Clin Oncol (2009) 6.77
Tumor self-seeding by circulating cancer cells. Cell (2009) 6.66
American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol (2003) 6.66
Recommendations for initial evaluation, staging, and response assessment of Hodgkin and non-Hodgkin lymphoma: the Lugano classification. J Clin Oncol (2014) 6.61
American Society of Clinical Oncology technology assessment on the use of aromatase inhibitors as adjuvant therapy for postmenopausal women with hormone receptor-positive breast cancer: status report 2004. J Clin Oncol (2004) 6.59
Lumpectomy plus tamoxifen with or without irradiation in women age 70 years or older with early breast cancer: long-term follow-up of CALGB 9343. J Clin Oncol (2013) 6.56
Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol (2002) 6.51
Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancer. JAMA (2006) 6.45
Dietary fat reduction and breast cancer outcome: interim efficacy results from the Women's Intervention Nutrition Study. J Natl Cancer Inst (2006) 6.41
Cardiac dysfunction in the trastuzumab clinical trials experience. J Clin Oncol (2002) 6.09
Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial. Lancet Oncol (2009) 5.73
Adjuvant chemotherapy in older women with early-stage breast cancer. N Engl J Med (2009) 5.68
Randomized trial of letrozole following tamoxifen as extended adjuvant therapy in receptor-positive breast cancer: updated findings from NCIC CTG MA.17. J Natl Cancer Inst (2005) 5.55
Breast cancer subtype approximated by estrogen receptor, progesterone receptor, and HER-2 is associated with local and distant recurrence after breast-conserving therapy. J Clin Oncol (2008) 5.28
Latent bone metastasis in breast cancer tied to Src-dependent survival signals. Cancer Cell (2009) 5.24
American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol (2009) 4.95
A CXCL1 paracrine network links cancer chemoresistance and metastasis. Cell (2012) 4.89
Genome-wide association study provides evidence for a breast cancer risk locus at 6q22.33. Proc Natl Acad Sci U S A (2008) 4.76
In Support of a Patient-Driven Initiative and Petition to Lower the High Price of Cancer Drugs. Mayo Clin Proc (2015) 4.70
American society of clinical oncology statement: toward individualized care for patients with advanced cancer. J Clin Oncol (2011) 4.64
American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting. J Clin Oncol (2006) 4.61
Central nervous system metastases in women who receive trastuzumab-based therapy for metastatic breast carcinoma. Cancer (2003) 4.47
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat Genet (2013) 4.35
Phase III trial of long-term adjuvant androgen deprivation after neoadjuvant hormonal cytoreduction and radiotherapy in locally advanced carcinoma of the prostate: the Radiation Therapy Oncology Group Protocol 92-02. J Clin Oncol (2003) 4.33
Novel patterns of genome rearrangement and their association with survival in breast cancer. Genome Res (2006) 4.25
A failure analysis of invasive breast cancer: most deaths from disease occur in women not regularly screened. Cancer (2013) 4.21
Phase III randomized trial of cisplatin plus placebo compared with cisplatin plus cetuximab in metastatic/recurrent head and neck cancer: an Eastern Cooperative Oncology Group study. J Clin Oncol (2005) 4.16
Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer. Cancer Res (2005) 4.13
Adherence to initial adjuvant anastrozole therapy among women with early-stage breast cancer. J Clin Oncol (2008) 4.06
Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm. J Biol Chem (2009) 4.05
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer. Nat Genet (2013) 4.03
Triple-negative breast cancer: disease entity or title of convenience? Nat Rev Clin Oncol (2010) 3.98
Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline. J Clin Oncol (2007) 3.91
Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study. Blood (2006) 3.85
Outcomes for elderly, advanced-stage non small-cell lung cancer patients treated with bevacizumab in combination with carboplatin and paclitaxel: analysis of Eastern Cooperative Oncology Group Trial 4599. J Clin Oncol (2008) 3.83
Why do patients choose chemotherapy near the end of life? A review of the perspective of those facing death from cancer. J Clin Oncol (2006) 3.71
Early specialty palliative care--translating data in oncology into practice. N Engl J Med (2013) 3.58
Risk-reducing salpingo-oophorectomy for the prevention of BRCA1- and BRCA2-associated breast and gynecologic cancer: a multicenter, prospective study. J Clin Oncol (2008) 3.54
Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B. J Clin Oncol (2006) 3.50
Adjuvant chemotherapy in older and younger women with lymph node-positive breast cancer. JAMA (2005) 3.43
Late extended adjuvant treatment with letrozole improves outcome in women with early-stage breast cancer who complete 5 years of tamoxifen. J Clin Oncol (2008) 3.40
Prospective study of wide excision alone for ductal carcinoma in situ of the breast. J Clin Oncol (2006) 3.33
The role of chemotherapy at the end of life: "when is enough, enough?". JAMA (2008) 3.31
2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer. J Clin Oncol (2011) 3.21
Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer. J Clin Oncol (2007) 3.19
Breast cancer. Clinical practice guidelines in oncology. J Natl Compr Canc Netw (2009) 3.17
Personalized medicine in a phase I clinical trials program: the MD Anderson Cancer Center initiative. Clin Cancer Res (2012) 3.14
Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure (2008) 3.02
Tumor entrained neutrophils inhibit seeding in the premetastatic lung. Cancer Cell (2011) 2.96
Competing causes of death from a randomized trial of extended adjuvant endocrine therapy for breast cancer. J Natl Cancer Inst (2008) 2.94