Published in J Clin Oncol on July 20, 2006
Aggressiveness of cancer care near the end of life: is it a quality-of-care issue? J Clin Oncol (2008) 5.61
Bending the cost curve in cancer care. N Engl J Med (2011) 5.02
American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol (2009) 4.95
Associations between palliative chemotherapy and adult cancer patients' end of life care and place of death: prospective cohort study. BMJ (2014) 3.90
Physician factors associated with discussions about end-of-life care. Cancer (2010) 3.54
The role of chemotherapy at the end of life: "when is enough, enough?". JAMA (2008) 3.31
What oncologists tell patients about survival benefits of palliative chemotherapy and implications for informed consent: qualitative study. BMJ (2008) 2.04
Drugs, cancer and end-of-life care: a case study of pharmaceuticalization? Soc Sci Med (2014) 2.03
The effect on survival of continuing chemotherapy to near death. BMC Palliat Care (2011) 1.66
High-cost imaging in elderly patients with stage IV cancer. J Natl Cancer Inst (2012) 1.63
Communication about cancer near the end of life. Cancer (2008) 1.40
A pilot trial of decision aids to give truthful prognostic and treatment information to chemotherapy patients with advanced cancer. J Support Oncol (2011) 1.38
The value of progression-free survival to patients with advanced-stage cancer. Nat Rev Clin Oncol (2011) 1.33
Hospice care and survival among elderly patients with lung cancer. J Palliat Med (2011) 1.22
Does it matter what you call it? A randomized trial of language used to describe palliative care services. Support Care Cancer (2013) 1.21
Antineoplastic therapy use in patients with advanced cancer admitted to an acute palliative care unit at a comprehensive cancer center: a simultaneous care model. Cancer (2010) 1.19
Barriers to referral to inpatient palliative care units in Japan: a qualitative survey with content analysis. Support Care Cancer (2007) 1.19
First-line treatment with oxaliplatin and capecitabine in patients with advanced or metastatic oesophageal cancer: a phase II study. Br J Cancer (2007) 1.08
Understanding patient perspectives on communication about the cost of cancer care: a review of the literature. J Oncol Pract (2010) 1.07
Using claims-based measures to predict performance status score in patients with lung cancer. Cancer (2010) 1.05
Integration of palliative care practices into the ongoing care of children with cancer: individualized care planning and coordination. Pediatr Clin North Am (2008) 1.03
Palliative care needs of cancer outpatients receiving chemotherapy: an audit of a clinical screening project. Support Care Cancer (2007) 0.97
Impact of aggressive management and palliative care on cancer costs in the final month of life. Cancer (2015) 0.96
Testing personalized medicine: patient and physician expectations of next-generation genomic sequencing in late-stage cancer care. Eur J Hum Genet (2013) 0.96
Out-of-pocket expenses and treatment choice for men with prostate cancer. Urology (2012) 0.92
Use of chemotherapy at the end of life in a Portuguese oncology center. Support Care Cancer (2007) 0.91
Health economics of a palliative care unit for terminal cancer patients: a retrospective cohort study. Support Care Cancer (2010) 0.88
Enhancing treatment decision-making: pilot study of a treatment decision aid in stage IV non-small cell lung cancer. Br J Cancer (2008) 0.88
When doctors and patients disagree about medical futility. J Oncol Pract (2008) 0.88
Chemotherapy in patients with advanced pancreatic cancer: too close to death? Support Care Cancer (2012) 0.88
End-of-Life Medical Costs of Medicaid Cancer Patients. Health Serv Res (2014) 0.87
Surprise Questions for Survival Prediction in Patients With Advanced Cancer: A Multicenter Prospective Cohort Study. Oncologist (2015) 0.85
Neutrophil to lymphocyte ratio in the pre-treatment phase of final-line chemotherapy predicts the outcome of patients with recurrent ovarian cancer. Oncol Lett (2016) 0.84
Protective effects of green tea polyphenol against cisplatin-induced nephrotoxicity in rats. Obstet Gynecol Sci (2014) 0.83
Endpoints in advanced breast cancer: methodological aspects & clinical implications. Indian J Med Res (2011) 0.82
Sequential Metastatic Breast Cancer Chemotherapy: Should the Median be the Message? Front Public Health (2013) 0.82
Commentary: "the Lake Wobegon effect, a natural human tendency to overestimate one's capabilities" (Wikipedia). Milbank Q (2013) 0.82
Trends in the Aggressiveness of End-of-Life Care for Advanced Stomach Cancer Patients. Cancer Res Treat (2013) 0.81
Do unto others... J Clin Oncol (2006) 0.81
The role of palliative chemotherapy in hospitalized patients. Curr Oncol (2014) 0.81
Chemotherapy at end-of-life: an integration of oncology and palliative team. Support Care Cancer (2015) 0.79
Treatment priorities in oncology: do we want to live longer or better? Clinics (Sao Paulo) (2014) 0.79
Intensity of Medical Interventions between Diagnosis and Death in Patients with Advanced Lung and Colorectal Cancer: A CanCORS Analysis. J Palliat Med (2015) 0.78
Prediction of survival in terminally ill cancer patients at the time of terminal cancer diagnosis. J Cancer Res Clin Oncol (2014) 0.78
Hope, quality of life, and benefit from treatment in women having chemotherapy for platinum-resistant/refractory recurrent ovarian cancer: the gynecologic cancer intergroup symptom benefit study. Oncologist (2013) 0.78
Framework for timing of the discussion about forgoing cancer-specific treatment based on a qualitative study with oncologists. Support Care Cancer (2014) 0.78
The debate in hospice care. J Oncol Pract (2008) 0.78
Determinants for aggressive end-of-life care for oral cancer patients: a population-based study in an Asian country. Medicine (Baltimore) (2015) 0.77
Patients' perspectives on palliative chemotherapy of colorectal and non--colorectal cancer: a prospective study in a chemotherapy- experienced population. BMC Cancer (2013) 0.77
The Developmental Transition From Living With to Dying From Cancer: Hospice Decision Making. J Psychosoc Oncol (2015) 0.77
The Attitudes of Chinese Cancer Patients and Family Caregivers toward Advance Directives. Int J Environ Res Public Health (2016) 0.75
Perspectives of Medical Specialists on Sharing Decisions in Cancer Care: A Qualitative Study Concerning Chemotherapy Decisions With Patients With Recurrent Glioblastoma. Oncologist (2015) 0.75
Reflection of illness and strategies for handling advanced lung cancer - a qualitative analysis in patients and their relatives. BMC Health Serv Res (2017) 0.75
Palliative care: Lemonade from lemons: exploring the results of the VOICE study. Nat Rev Clin Oncol (2016) 0.75
Palliative care team visits. Qualitative study through participant observation. Colomb Med (Cali) (2016) 0.75
A retrospective analysis of factors associated with selection of end-of-life care and actual place of death for patients with cancer. BMJ Open (2014) 0.75
Understanding the complexities of shared decision-making in cancer: a qualitative study of the perspectives of patients undergoing colorectal surgery. Can J Surg (2016) 0.75
Terminal Versus Advanced Cancer: Do the General Population and Health Care Professionals Share a Common Language? Cancer Res Treat (2015) 0.75
Time, clinic technologies, and the making of reflexive longevity: the cultural work of time left in an ageing society. Sociol Health Illn (2010) 0.75
Palliative care in cancer: managing patients' expectations. J Med Radiat Sci (2016) 0.75
'Being there' for women with metastatic breast cancer: a pan-European patient survey. Br J Cancer (2013) 0.75
Living better or living longer? Perceptions of patients and health care professionals in oncology. Ecancermedicalscience (2015) 0.75
Treatment targeted at underlying disease versus palliative care in terminally ill patients: a systematic review. BMJ Open (2017) 0.75
Prognostic value of treatment-related factors in metastatic colorectal cancer using a stop-and-go strategy. Int J Colorectal Dis (2014) 0.75
Development of an advance care planning paradigm for advanced cancer: person-centered oncologic care and choices (P-COCC). Psychooncology (2016) 0.75
Aggressiveness of cancer treatment in patients hospitalized in a supportive care unit. Support Care Cancer (2014) 0.75
Impact of intervention aimed at improving the integration of oncology units and local palliative care services: results of the multicentre prospective sequential MIRTO study. ESMO Open (2017) 0.75
The importance of good death components among cancer patients, the general population, oncologists, and oncology nurses in Japan: patients prefer "fighting against cancer". Support Care Cancer (2014) 0.75
Specific anticancer treatments in the last 3 months of life: a French experience. Support Care Cancer (2012) 0.75
Decisions for lung cancer chemotherapy: the influence of physician and patient factors. Support Care Cancer (2011) 0.75
Patient-Centered Outcome Measures in Lung Cancer Trials. Lung (2016) 0.75
Active treatment given in the last weeks of life: poor quality cancer care or justifiable behavior? Support Care Cancer (2014) 0.75
The genome sequence of the malaria mosquito Anopheles gambiae. Science (2002) 20.36
A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science (2002) 9.59
American Society of Clinical Oncology identifies five key opportunities to improve care and reduce costs: the top five list for oncology. J Clin Oncol (2012) 7.16
American Society of Clinical Oncology guidance statement: the cost of cancer care. J Clin Oncol (2009) 6.77
American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol (2003) 6.66
American Society of Clinical Oncology Clinical Practice Guideline update on chemotherapy for stage IV non-small-cell lung cancer. J Clin Oncol (2009) 4.95
Lumpectomy plus tamoxifen with or without irradiation in women 70 years of age or older with early breast cancer. N Engl J Med (2004) 4.84
American society of clinical oncology statement: toward individualized care for patients with advanced cancer. J Clin Oncol (2011) 4.64
American Society of Clinical Oncology 2006 update of the breast cancer follow-up and management guidelines in the adjuvant setting. J Clin Oncol (2006) 4.61
Complex glycan catabolism by the human gut microbiota: the Bacteroidetes Sus-like paradigm. J Biol Chem (2009) 4.05
Initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer: 2006 update of an American Society of Clinical Oncology practice guideline. J Clin Oncol (2007) 3.91
Early specialty palliative care--translating data in oncology into practice. N Engl J Med (2013) 3.58
The role of chemotherapy at the end of life: "when is enough, enough?". JAMA (2008) 3.31
2011 Focused Update of 2009 American Society of Clinical Oncology Clinical Practice Guideline Update on Chemotherapy for Stage IV Non-Small-Cell Lung Cancer. J Clin Oncol (2011) 3.21
Starch catabolism by a prominent human gut symbiont is directed by the recognition of amylose helices. Structure (2008) 3.02
The shortage of essential chemotherapy drugs in the United States. N Engl J Med (2011) 2.74
Palliative care and oncology partnerships in real practice. Oncology (Williston Park) (2011) 2.72
Breast cancer follow-up and management after primary treatment: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol (2012) 2.62
Talking with patients about dying. N Engl J Med (2012) 2.34
Hospital mortality rates: how is palliative care taken into account? J Pain Symptom Manage (2010) 2.32
Arsenic methylation and skin cancer risk in southwestern Taiwan. J Occup Environ Med (2003) 2.11
Lung cancer in railroad workers exposed to diesel exhaust. Environ Health Perspect (2004) 2.06
Providing pain and palliative care education internationally. J Support Oncol (2011) 2.04
Lung cancer and elemental carbon exposure in trucking industry workers. Environ Health Perspect (2012) 2.04
Efficacy does not necessarily translate to cost effectiveness: a case study in the challenges associated with 21st-century cancer drug pricing. J Clin Oncol (2009) 2.03
Arsenic methylation and bladder cancer risk in Taiwan. Cancer Causes Control (2003) 1.86
Is it time for (survivorship care) plan B? J Clin Oncol (2011) 1.84
Residential exposure to petrochemicals and the risk of leukemia: using geographic information system tools to estimate individual-level residential exposure. Am J Epidemiol (2006) 1.84
Advances in microbicide vaginal rings. Antiviral Res (2010) 1.76
SPIKE$: a six-step protocol for delivering bad news about the cost of medical care. J Clin Oncol (2008) 1.76
Spatial modeling of PM10 and NO2 in the continental United States, 1985-2000. Environ Health Perspect (2009) 1.73
Fatal Loeffler's endocarditis due to hypereosinophilic syndrome. Am J Hematol (2007) 1.73
The association of particulate air metal concentrations with heart rate variability. Environ Health Perspect (2002) 1.71
Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase. J Biol Chem (2010) 1.68
Green tea polyphenols modulate insulin secretion by inhibiting glutamate dehydrogenase. J Biol Chem (2006) 1.64
Reasons why physicians do not have discussions about poor prognosis, why it matters, and what can be improved. J Clin Oncol (2012) 1.60
Assessment of optimal size and composition of the U.S. National Registry of hematopoietic stem cell donors. Transplantation (2004) 1.59
Lung cancer and vehicle exhaust in trucking industry workers. Environ Health Perspect (2008) 1.57
Improving the quality of cancer care: implications for palliative care. J Palliat Med (2014) 1.49
Structure of antibody-neutralized murine norovirus and unexpected differences from viruslike particles. J Virol (2007) 1.49
Randomized trial of long-term follow-up for early-stage breast cancer: a comparison of family physician versus specialist care. J Clin Oncol (2006) 1.48
American Society of Clinical Oncology recommendations for the initial hormonal management of androgen-sensitive metastatic, recurrent, or progressive prostate cancer. J Clin Oncol (2004) 1.44
A randomized phase III study of radiotherapy alone or with 5-fluorouracil and mitomycin-C in patients with locally advanced adenocarcinoma of the pancreas: Eastern Cooperative Oncology Group study E8282. Int J Radiat Oncol Biol Phys (2005) 1.43
'Futile care': what to do when your patient insists on chemotherapy that likely won't help. Oncology (Williston Park) (2008) 1.42
Advance Care Planning Discussions: Why They Should Happen, Why They Don't, and How We Can Facilitate the Process. Oncology (Williston Park) (2015) 1.40
A case of inaccurate prognostication after the ARCTIC protocol. J Pain Symptom Manage (2012) 1.39
The association between personal measurements of environmental exposure to particulates and heart rate variability. Epidemiology (2002) 1.38
Simultaneous delivery of tenofovir and acyclovir via an intravaginal ring. Antimicrob Agents Chemother (2011) 1.38
An antibody to the putative aphid recognition site on cucumber mosaic virus recognizes pentons but not hexons. J Virol (2002) 1.35
Differential antifungal and calcium channel-blocking activity among structurally related plant defensins. Plant Physiol (2004) 1.35
Paradoxes in advance care planning: the complex relationship of oncology patients, their physicians, and advance medical directives. J Clin Oncol (2009) 1.30
Structural determinants of metal specificity in the zinc transport protein ZnuA from synechocystis 6803. J Mol Biol (2003) 1.30
Scrambler therapy may relieve chronic neuropathic pain more effectively than guideline-based drug management: results of a pilot, randomized, controlled trial. J Pain Symptom Manage (2011) 1.29
Long-term ambient multipollutant exposures and mortality. Am J Respir Crit Care Med (2010) 1.29
Historical estimation of diesel exhaust exposure in a cohort study of U.S. railroad workers and lung cancer. Cancer Causes Control (2006) 1.26
Structural basis for broad detection of genogroup II noroviruses by a monoclonal antibody that binds to a site occluded in the viral particle. J Virol (2012) 1.21
Cause-specific mortality in the unionized U.S. trucking industry. Environ Health Perspect (2007) 1.20
SusG: a unique cell-membrane-associated alpha-amylase from a prominent human gut symbiont targets complex starch molecules. Structure (2010) 1.20
Summary of the findings from the exposure assessments for metalworking fluid mortality and morbidity studies. Appl Occup Environ Hyg (2003) 1.19
High-resolution cryo-electron microscopy structures of murine norovirus 1 and rabbit hemorrhagic disease virus reveal marked flexibility in the receptor binding domains. J Virol (2010) 1.19
Novel inhibitors complexed with glutamate dehydrogenase: allosteric regulation by control of protein dynamics. J Biol Chem (2009) 1.17
An intravaginal ring for the simultaneous delivery of multiple drugs. J Pharm Sci (2012) 1.17
Human rhinovirus capsid dynamics is controlled by canyon flexibility. Virology (2003) 1.14
Skin exposure to isocyanates: reasons for concern. Environ Health Perspect (2006) 1.14
High-resolution x-ray structure and functional analysis of the murine norovirus 1 capsid protein protruding domain. J Virol (2010) 1.13
Safety and pharmacokinetics of intravaginal rings delivering tenofovir in pig-tailed macaques. Antimicrob Agents Chemother (2012) 1.11
The structure of a cyanobacterial bicarbonate transport protein, CmpA. J Biol Chem (2006) 1.11
Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. Biochemistry (2003) 1.10
Tenofovir and tenofovir disoproxil fumarate pharmacokinetics from intravaginal rings. AIDS (2012) 1.10
Comparison of fine particle measurements from a direct-reading instrument and a gravimetric sampling method. J Occup Environ Hyg (2004) 1.09
Wiser use of dose-dense adjuvant therapy in breast cancer. J Clin Oncol (2012) 1.09
Expression, purification and characterization of human glutamate dehydrogenase (GDH) allosteric regulatory mutations. Biochem J (2002) 1.08
Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont. Biochemistry (2009) 1.08
Cotton dust and endotoxin levels in three Shanghai textile factories: a comparison of samplers. J Occup Environ Hyg (2006) 1.07
Microbial biofilms on the surface of intravaginal rings worn in non-human primates. J Med Microbiol (2011) 1.07
Toenail arsenic concentrations, GSTT1 gene polymorphisms, and arsenic exposure from drinking water. Cancer Epidemiol Biomarkers Prev (2005) 1.06
Vehicle traffic as a source of particulate polycyclic aromatic hydrocarbon exposure in the Mexico City metropolitan area. Environ Sci Technol (2004) 1.05
Using claims-based measures to predict performance status score in patients with lung cancer. Cancer (2010) 1.05
Antibodies to the buried N terminus of rhinovirus VP4 exhibit cross-serotypic neutralization. J Virol (2009) 1.05
Evidence-based palliative care in the intensive care unit: a systematic review of interventions. J Palliat Med (2014) 1.05
Palliative care consultation and hospital length of stay. J Palliat Med (2010) 1.03
Do the large benefits justify the large costs of adjuvant breast cancer trastuzumab? J Clin Oncol (2007) 1.03
The structure and allosteric regulation of mammalian glutamate dehydrogenase. Arch Biochem Biophys (2011) 1.03
Lead burden and psychiatric symptoms and the modifying influence of the delta-aminolevulinic acid dehydratase (ALAD) polymorphism: the VA Normative Aging Study. Am J Epidemiol (2007) 1.02
Tracking personal exposure to particulate diesel exhaust in a diesel freight terminal using organic tracer analysis. J Expo Sci Environ Epidemiol (2008) 1.02
Pilot evaluation of Scrambler therapy for the treatment of chemotherapy-induced peripheral neuropathy. Support Care Cancer (2014) 1.02
Atomic structure of a nitrate-binding protein crucial for photosynthetic productivity. Proc Natl Acad Sci U S A (2006) 1.01
Possible regulatory role for the histidine-rich loop in the zinc transport protein, ZnuA. Biochemistry (2007) 1.01
Structure-activity determinants in antifungal plant defensins MsDef1 and MtDef4 with different modes of action against Fusarium graminearum. PLoS One (2011) 1.01
Smoking behavior in trucking industry workers. Am J Ind Med (2006) 1.01
Using a water-immiscible ionic liquid to improve asymmetric reduction of 4-(trimethylsilyl)-3-butyn-2-one catalyzed by immobilized Candida parapsilosis CCTCC M203011 cells. BMC Biotechnol (2009) 0.99
Remediation of chromium(VI) by a methane-oxidizing bacterium. Environ Sci Technol (2010) 0.99
Evolution of glutamate dehydrogenase regulation of insulin homeostasis is an example of molecular exaptation. Biochemistry (2004) 0.99
Survival among non-small cell lung cancer patients with poor performance status after first line chemotherapy. Lung Cancer (2012) 0.98
Land crabs as key drivers in tropical coastal forest recruitment. Biol Rev Camb Philos Soc (2009) 0.98
Multidomain Carbohydrate-binding Proteins Involved in Bacteroides thetaiotaomicron Starch Metabolism. J Biol Chem (2012) 0.98
A trial of Scrambler therapy in the treatment of cancer pain syndromes and chronic chemotherapy-induced peripheral neuropathy. J Pain Palliat Care Pharmacother (2013) 0.98
Green tea polyphenols control dysregulated glutamate dehydrogenase in transgenic mice by hijacking the ADP activation site. J Biol Chem (2011) 0.98
Pharmacokinetics of a multipurpose pod-intravaginal ring simultaneously delivering five drugs in an ovine model. Antimicrob Agents Chemother (2013) 0.97
Economic activity and trends in ambient air pollution. Environ Health Perspect (2010) 0.95