Published in J Am Chem Soc on September 22, 2004
Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasome. J Biol Chem (2008) 1.93
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins. J Am Chem Soc (2006) 1.60
Physical and functional interactions of monoubiquitylated transactivators with the proteasome. J Biol Chem (2008) 1.08
Label transfer chemistry for the characterization of protein-protein interactions. J Am Chem Soc (2007) 1.07
Coating proteins: structure and cross-linking in fp-1 from the green shell mussel Perna canaliculus. Biochemistry (2005) 1.04
Histones: at the crossroads of peptide and protein chemistry. Chem Rev (2014) 1.01
Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chem Biol (2009) 1.00
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. J Am Chem Soc (2007) 0.93
Site-specific protein cross-linking with genetically incorporated 3,4-dihydroxy-L-phenylalanine. Chembiochem (2009) 0.89
Cross-linking of a DOPA-containing peptide ligand into its G protein-coupled receptor. Biochemistry (2009) 0.86
Identification of residue-to-residue contact between a peptide ligand and its G protein-coupled receptor using periodate-mediated dihydroxyphenylalanine cross-linking and mass spectrometry. J Biol Chem (2010) 0.84
Structure-based non-canonical amino acid design to covalently crosslink an antibody-antigen complex. J Struct Biol (2013) 0.80
Peptoid ligands that bind selectively to phosphoproteins. Bioorg Med Chem Lett (2011) 0.80
Novobiocin and peptide analogs of α-factor are positive allosteric modulators of the yeast G protein-coupled receptor Ste2p. Biochim Biophys Acta (2015) 0.76
A versatile approach to transform low-affinity peptides into protein probes with cotranslationally expressed chemical cross-linker. Anal Biochem (2010) 0.76
Nanomechanical characterization of chemical interaction between gold nanoparticles and chemical functional groups. Nanoscale Res Lett (2012) 0.75
3,4-Dihydroxyphenylalanine Peptides as Nonperturbative Quantum Dot Sensors of Aminopeptidase. ACS Nano (2016) 0.75
Inducible, Site-Specific Protein Labeling by Tyrosine Oxidation-Strain-Promoted (4 + 2) Cycloaddition. Bioconjug Chem (2017) 0.75
Chemical Tools To Monitor and Manipulate Adaptive Immune Responses. J Am Chem Soc (2016) 0.75
Recruitment of a 19S proteasome subcomplex to an activated promoter. Science (2002) 4.01
Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening. Cell (2011) 3.01
Isolation of protein ligands from large peptoid libraries. J Am Chem Soc (2003) 2.80
Histone deacetylase (HDAC) inhibitors attenuate cardiac hypertrophy by suppressing autophagy. Proc Natl Acad Sci U S A (2011) 2.80
A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity. J Am Chem Soc (2008) 2.47
Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation (2014) 2.07
Proteasomes: machines for all reasons. Cell (2007) 2.03
Microwave-assisted solid-phase synthesis of peptoids. Org Lett (2002) 1.81
Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries. Chem Biol (2010) 1.67
Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice. J Clin Invest (2012) 1.63
Physical and functional association of RNA polymerase II and the proteasome. Proc Natl Acad Sci U S A (2004) 1.61
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins. J Am Chem Soc (2006) 1.60
A high-throughput assay for assessing the cell permeability of combinatorial libraries. Nat Biotechnol (2005) 1.54
Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo. Nature (2006) 1.49
A biomimetic polyketide-inspired approach to small-molecule ligand discovery. Nat Chem (2011) 1.49
Peptoids as potential therapeutics. Curr Opin Mol Ther (2009) 1.49
Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Mol Biosyst (2006) 1.47
Target identification in chemical genetics: the (often) missing link. Chem Biol (2004) 1.47
Quantitative evaluation of the relative cell permeability of peptoids and peptides. J Am Chem Soc (2007) 1.44
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle. J Am Chem Soc (2007) 1.36
The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain. Magn Reson Imaging (2008) 1.33
Protein "fingerprinting" in complex mixtures with peptoid microarrays. Proc Natl Acad Sci U S A (2005) 1.33
Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides. Chem Biol (2013) 1.32
The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters. Genes Dev (2006) 1.32
A nonproteolytic function of the 19S regulatory subunit of the 26S proteasome is required for efficient activated transcription by human RNA polymerase II. Biochemistry (2002) 1.30
A cell-permeable synthetic transcription factor mimic. Angew Chem Int Ed Engl (2007) 1.29
Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets. Drug Discov Today Dis Mech (2010) 1.28
Widespread, but non-identical, association of proteasomal 19 and 20 S proteins with yeast chromatin. J Biol Chem (2006) 1.27
Genomic studies of transcription factor-DNA interactions. Curr Opin Chem Biol (2005) 1.21
Quantum dots as a visual aid for screening bead-bound combinatorial libraries. Chembiochem (2003) 1.20
STIM1-dependent store-operated Ca²⁺ entry is required for pathological cardiac hypertrophy. J Mol Cell Cardiol (2011) 1.18
Design and synthesis of a cell-permeable synthetic transcription factor mimic. J Comb Chem (2007) 1.17
Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking. Mol Biosyst (2005) 1.15
Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Res (2010) 1.13
Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries. ACS Comb Sci (2012) 1.11
Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits. ACS Comb Sci (2014) 1.10
High-throughput evaluation of relative cell permeability between peptoids and peptides. Bioorg Med Chem (2008) 1.09
MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting. J Am Chem Soc (2010) 1.08
Physical and functional interactions of monoubiquitylated transactivators with the proteasome. J Biol Chem (2008) 1.08
Magnetic resonance imaging detects a specific peptide-protein binding event. J Am Chem Soc (2002) 1.08
Discovery of peptoid ligands for anti-aquaporin 4 antibodies. Chem Biol (2013) 1.07
Acyl hydrazides as peptoid sub-monomers. Chem Commun (Camb) (2011) 1.07
Label transfer chemistry for the characterization of protein-protein interactions. J Am Chem Soc (2007) 1.07
The proteasomal ATPase complex is required for stress-induced transcription in yeast. Nucleic Acids Res (2006) 1.06
Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain. Org Biomol Chem (2013) 1.05
Transformation of low-affinity lead compounds into high-affinity protein capture agents. Chem Biol (2004) 1.04
Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nat Chem Biol (2010) 1.03
The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues. Bioorg Med Chem Lett (2008) 1.03
Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy. Cardiovasc Res (2011) 1.03
Isolation and characterization of coactivator-binding peptoids from a combinatorial library. Mol Biosyst (2006) 1.02
A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Mol Biosyst (2007) 1.02
Selective toxin sequestrants for the treatment of bacterial infections. J Am Chem Soc (2009) 1.01
Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chem Biol (2009) 1.00
Quantitative comparison of the relative cell permeability of cyclic and linear peptides. Chem Biol (2007) 1.00
FHL2 binds calcineurin and represses pathological cardiac growth. Mol Cell Biol (2012) 1.00
The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. Genes Dev (2007) 1.00
Toward a general chemical method for rapidly mapping multi-protein complexes. J Proteome Res (2004) 0.99
Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle. Chem Commun (Camb) (2008) 0.98
Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy. Chem Commun (Camb) (2005) 0.96
A potent transactivation domain mimic with activity in living cells. J Am Chem Soc (2005) 0.96
Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo. J Biol Chem (2008) 0.96
Discovery of native autoantigens via antigen surrogate technology: application to type 1 diabetes. ACS Chem Biol (2014) 0.95
Cardiomyocyte autophagy: remodeling, repairing, and reconstructing the heart. Curr Hypertens Rep (2009) 0.95
Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease. Chem Biol (2011) 0.94
Mechanical unloading activates FoxO3 to trigger Bnip3-dependent cardiomyocyte atrophy. J Am Heart Assoc (2013) 0.94
Physical association of the APIS complex and general transcription factors. Biochem Biophys Res Commun (2002) 0.93
Simple reporter gene-based assays for hairpin poly(amide) conjugate permeability and DNA-binding activity in living cells. Mol Biosyst (2005) 0.93
A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. ACS Chem Biol (2013) 0.93
Submonomer synthesis of a hybrid peptoid-azapeptoid library. ACS Comb Sci (2012) 0.93
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. J Am Chem Soc (2007) 0.93
Protein affinity labeling mediated by genetically encoded peptide tags. Angew Chem Int Ed Engl (2002) 0.90
Rapid identification of improved protein ligands using peptoid microarrays. Bioorg Med Chem Lett (2009) 0.90
Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry. J Am Soc Mass Spectrom (2013) 0.89
Rapid lead discovery through iterative screening of one bead one compound libraries. ACS Comb Sci (2014) 0.89
Transcription activation by a PNA-peptide chimera in a mammalian cell extract. Chem Biol (2003) 0.89
Dynamics of the hypoxia-inducible factor-1-vascular endothelial growth factor promoter complex. J Biol Chem (2007) 0.88
Nucleotide excision repair and the ubiquitin proteasome pathway--do all roads lead to Rome? DNA Repair (Amst) (2006) 0.88
Features of modularly assembled compounds that impart bioactivity against an RNA target. ACS Chem Biol (2013) 0.88
Encoded combinatorial libraries for the construction of cyclic peptoid microarrays. Chem Commun (Camb) (2008) 0.87
Immobilized peptides as high-affinity capture agents for self-associating proteins. Chem Biol (2003) 0.87
Peptides as modulators of enzymes and regulatory proteins. Methods (2004) 0.86
Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads. Mol Biosyst (2009) 0.85
Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides. J Med Chem (2009) 0.85
Photolithographic synthesis of peptoids. J Am Chem Soc (2004) 0.85
Solid-phase synthesis of diverse peptide tertiary amides by reductive amination. ACS Comb Sci (2015) 0.84
Use of peptide analogue diversity library beads for increased depth of proteomic analysis: application to cerebrospinal fluid. J Proteome Res (2008) 0.84
Cardiomyocyte ryanodine receptor degradation by chaperone-mediated autophagy. Cardiovasc Res (2013) 0.84
A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry. Tetrahedron Lett (2012) 0.83
A peptoid antagonist of VEGF receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site. Bioorg Med Chem (2008) 0.83
Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and efficient promoter occupancy. Mol Biosyst (2008) 0.83
Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands. J Am Chem Soc (2003) 0.83
Toward synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera. J Am Chem Soc (2002) 0.81
Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands. Bioconjug Chem (2014) 0.81
The hydrophobic patch of ubiquitin is required to protect transactivator-promoter complexes from destabilization by the proteasomal ATPases. Nucleic Acids Res (2009) 0.80
Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases. J Biol Chem (2009) 0.80
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. Bioconjug Chem (2015) 0.80
Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units. Org Biomol Chem (2014) 0.80
Characterization of proteomic and metabolomic responses to dietary factors and supplements. J Nutr (2007) 0.80
A convenient, high-throughput assay for measuring the relative cell permeability of synthetic compounds. Nat Protoc (2007) 0.80