Published in Chem Biol on June 01, 2007
Efficient delivery of cyclic peptides into mammalian cells with short sequence motifs. ACS Chem Biol (2012) 1.04
Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion. Nat Chem Biol (2012) 0.98
Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery. Biochemistry (2014) 0.97
Cyclic peptides as therapeutic agents and biochemical tools. Biomol Ther (Seoul) (2012) 0.94
Improved assays for determining the cytosolic access of peptides, proteins, and their mimetics. Biochemistry (2013) 0.90
Fluorescence correlation spectroscopy reveals highly efficient cytosolic delivery of certain penta-arg proteins and stapled peptides. J Am Chem Soc (2015) 0.89
Development of homomultimers and heteromultimers of lung cancer-specific peptoids. Biopolymers (2011) 0.85
Peptide bicycles that inhibit the Grb2 SH2 domain. Chembiochem (2012) 0.85
Screening helix-threading peptides for RNA binding using a thiazole orange displacement assay. Bioorg Med Chem (2008) 0.83
Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues. Mol Biosyst (2015) 0.78
A bicyclic peptide scaffold promotes phosphotyrosine mimicry and cellular uptake. Bioorg Med Chem (2014) 0.77
Getting across the cell membrane: an overview for small molecules, peptides, and proteins. Methods Mol Biol (2015) 0.76
A novel BK channel-targeted peptide suppresses sound evoked activity in the mouse inferior colliculus. Sci Rep (2017) 0.75
Synthesis of Hybrid Cyclopeptides through Enzymatic Macrocyclization. ChemistryOpen (2016) 0.75
Highly Constrained Bicyclic Scaffolds for the Discovery of Protease-Stable Peptides via mRNA Display. ACS Chem Biol (2017) 0.75
Recruitment of a 19S proteasome subcomplex to an activated promoter. Science (2002) 4.01
Identification of candidate IgG biomarkers for Alzheimer's disease via combinatorial library screening. Cell (2011) 3.01
Isolation of protein ligands from large peptoid libraries. J Am Chem Soc (2003) 2.80
A peptoid "antibody surrogate" that antagonizes VEGF receptor 2 activity. J Am Chem Soc (2008) 2.47
Microwave-assisted solid-phase synthesis of peptoids. Org Lett (2002) 1.81
Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries. Chem Biol (2010) 1.67
Physical and functional association of RNA polymerase II and the proteasome. Proc Natl Acad Sci U S A (2004) 1.61
Chemistry of periodate-mediated cross-linking of 3,4-dihydroxylphenylalanine-containing molecules to proteins. J Am Chem Soc (2006) 1.60
A high-throughput assay for assessing the cell permeability of combinatorial libraries. Nat Biotechnol (2005) 1.54
Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo. Nature (2006) 1.49
A biomimetic polyketide-inspired approach to small-molecule ligand discovery. Nat Chem (2011) 1.49
Peptoids as potential therapeutics. Curr Opin Mol Ther (2009) 1.49
Genome-wide analysis of human HSF1 signaling reveals a transcriptional program linked to cellular adaptation and survival. Mol Biosyst (2006) 1.47
Target identification in chemical genetics: the (often) missing link. Chem Biol (2004) 1.47
Quantitative evaluation of the relative cell permeability of peptoids and peptides. J Am Chem Soc (2007) 1.44
Identification of a peptoid inhibitor of the proteasome 19S regulatory particle. J Am Chem Soc (2007) 1.36
The detection limit of a Gd3+-based T1 agent is substantially reduced when targeted to a protein microdomain. Magn Reson Imaging (2008) 1.33
Protein "fingerprinting" in complex mixtures with peptoid microarrays. Proc Natl Acad Sci U S A (2005) 1.33
Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides. Chem Biol (2013) 1.32
The role of the proteasomal ATPases and activator monoubiquitylation in regulating Gal4 binding to promoters. Genes Dev (2006) 1.32
A nonproteolytic function of the 19S regulatory subunit of the 26S proteasome is required for efficient activated transcription by human RNA polymerase II. Biochemistry (2002) 1.30
A cell-permeable synthetic transcription factor mimic. Angew Chem Int Ed Engl (2007) 1.29
Widespread, but non-identical, association of proteasomal 19 and 20 S proteins with yeast chromatin. J Biol Chem (2006) 1.27
Periodate-triggered cross-linking of DOPA-containing peptide-protein complexes. J Am Chem Soc (2004) 1.24
Genomic studies of transcription factor-DNA interactions. Curr Opin Chem Biol (2005) 1.21
Quantum dots as a visual aid for screening bead-bound combinatorial libraries. Chembiochem (2003) 1.20
Design and synthesis of a cell-permeable synthetic transcription factor mimic. J Comb Chem (2007) 1.17
Identification of Gal4 activation domain-binding proteins in the 26S proteasome by periodate-triggered cross-linking. Mol Biosyst (2005) 1.15
Steroid receptor coactivator-3 expression in lung cancer and its role in the regulation of cancer cell survival and proliferation. Cancer Res (2010) 1.13
Incorporation of heterocycles into the backbone of peptoids to generate diverse peptoid-inspired one bead one compound libraries. ACS Comb Sci (2012) 1.11
Utility of redundant combinatorial libraries in distinguishing high and low quality screening hits. ACS Comb Sci (2014) 1.10
High-throughput evaluation of relative cell permeability between peptoids and peptides. Bioorg Med Chem (2008) 1.09
MRI detection of VEGFR2 in vivo using a low molecular weight peptoid-(Gd)8-dendron for targeting. J Am Chem Soc (2010) 1.08
Physical and functional interactions of monoubiquitylated transactivators with the proteasome. J Biol Chem (2008) 1.08
Magnetic resonance imaging detects a specific peptide-protein binding event. J Am Chem Soc (2002) 1.08
Acyl hydrazides as peptoid sub-monomers. Chem Commun (Camb) (2011) 1.07
Label transfer chemistry for the characterization of protein-protein interactions. J Am Chem Soc (2007) 1.07
Discovery of peptoid ligands for anti-aquaporin 4 antibodies. Chem Biol (2013) 1.07
The proteasomal ATPase complex is required for stress-induced transcription in yeast. Nucleic Acids Res (2006) 1.06
Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain. Org Biomol Chem (2013) 1.05
Transformation of low-affinity lead compounds into high-affinity protein capture agents. Chem Biol (2004) 1.04
Potent and selective photo-inactivation of proteins with peptoid-ruthenium conjugates. Nat Chem Biol (2010) 1.03
The pharmacophore of a peptoid VEGF receptor 2 antagonist includes both side chain and main chain residues. Bioorg Med Chem Lett (2008) 1.03
Isolation and characterization of coactivator-binding peptoids from a combinatorial library. Mol Biosyst (2006) 1.02
A general system for evaluating the efficiency of chromophore-assisted light inactivation (CALI) of proteins reveals Ru(II) tris-bipyridyl as an unusually efficient "warhead". Mol Biosyst (2007) 1.02
Selective toxin sequestrants for the treatment of bacterial infections. J Am Chem Soc (2009) 1.01
Isolation of antagonists of antigen-specific autoimmune T cell proliferation. Chem Biol (2009) 1.00
The neurohormone orexin stimulates hypoxia-inducible factor-1 activity. Genes Dev (2007) 1.00
Toward a general chemical method for rapidly mapping multi-protein complexes. J Proteome Res (2004) 0.99
Rapid identification of the pharmacophore in a peptoid inhibitor of the proteasome regulatory particle. Chem Commun (Camb) (2008) 0.98
Photolithographic synthesis of cyclic peptide arrays using a differential deprotection strategy. Chem Commun (Camb) (2005) 0.96
A potent transactivation domain mimic with activity in living cells. J Am Chem Soc (2005) 0.96
Activation domain-dependent monoubiquitylation of Gal4 protein is essential for promoter binding in vivo. J Biol Chem (2008) 0.96
Discovery of native autoantigens via antigen surrogate technology: application to type 1 diabetes. ACS Chem Biol (2014) 0.95
Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease. Chem Biol (2011) 0.94
Physical association of the APIS complex and general transcription factors. Biochem Biophys Res Commun (2002) 0.93
Simple reporter gene-based assays for hairpin poly(amide) conjugate permeability and DNA-binding activity in living cells. Mol Biosyst (2005) 0.93
A liquid array platform for the multiplexed analysis of synthetic molecule-protein interactions. ACS Chem Biol (2013) 0.93
Periodate-triggered cross-linking reveals Sug2/Rpt4 as the molecular target of a peptoid inhibitor of the 19S proteasome regulatory particle. J Am Chem Soc (2007) 0.93
Submonomer synthesis of a hybrid peptoid-azapeptoid library. ACS Comb Sci (2012) 0.93
Protein affinity labeling mediated by genetically encoded peptide tags. Angew Chem Int Ed Engl (2002) 0.90
Rapid identification of improved protein ligands using peptoid microarrays. Bioorg Med Chem Lett (2009) 0.90
Decoding split and pool combinatorial libraries with electron-transfer dissociation tandem mass spectrometry. J Am Soc Mass Spectrom (2013) 0.89
Rapid lead discovery through iterative screening of one bead one compound libraries. ACS Comb Sci (2014) 0.89
Transcription activation by a PNA-peptide chimera in a mammalian cell extract. Chem Biol (2003) 0.89
Dynamics of the hypoxia-inducible factor-1-vascular endothelial growth factor promoter complex. J Biol Chem (2007) 0.88
Features of modularly assembled compounds that impart bioactivity against an RNA target. ACS Chem Biol (2013) 0.88
Encoded combinatorial libraries for the construction of cyclic peptoid microarrays. Chem Commun (Camb) (2008) 0.87
Immobilized peptides as high-affinity capture agents for self-associating proteins. Chem Biol (2003) 0.87
Peptides as modulators of enzymes and regulatory proteins. Methods (2004) 0.86
Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides. J Med Chem (2009) 0.85
Rapid identification of orexin receptor binding ligands using cell-based screening accelerated with magnetic beads. Mol Biosyst (2009) 0.85
Photolithographic synthesis of peptoids. J Am Chem Soc (2004) 0.85
Solid-phase synthesis of diverse peptide tertiary amides by reductive amination. ACS Comb Sci (2015) 0.84
Use of peptide analogue diversity library beads for increased depth of proteomic analysis: application to cerebrospinal fluid. J Proteome Res (2008) 0.84
A Cleavable Scaffold Strategy for the Synthesis of One-Bead One-Compound Cyclic Peptoid Libraries That Can Be Sequenced By Tandem Mass Spectrometry. Tetrahedron Lett (2012) 0.83
A peptoid antagonist of VEGF receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site. Bioorg Med Chem (2008) 0.83
Mixed-element capture agents: a simple strategy for the construction of synthetic, high-affinity protein capture ligands. J Am Chem Soc (2003) 0.83
Phosphorylation of the Gal4 DNA-binding domain is essential for activator mono-ubiquitylation and efficient promoter occupancy. Mol Biosyst (2008) 0.83
Dextran as a generally applicable multivalent scaffold for improving immunoglobulin-binding affinities of peptide and peptidomimetic ligands. Bioconjug Chem (2014) 0.81
Toward synthetic transcription activators: recruitment of transcription factors to DNA by a PNA-peptide chimera. J Am Chem Soc (2002) 0.81
Characterization of proteomic and metabolomic responses to dietary factors and supplements. J Nutr (2007) 0.80
Solid-phase synthesis of peptoid-like oligomers containing diverse diketopiperazine units. Org Biomol Chem (2014) 0.80
A convenient, high-throughput assay for measuring the relative cell permeability of synthetic compounds. Nat Protoc (2007) 0.80
The hydrophobic patch of ubiquitin is required to protect transactivator-promoter complexes from destabilization by the proteasomal ATPases. Nucleic Acids Res (2009) 0.80
Peptoid ligands that bind selectively to phosphoproteins. Bioorg Med Chem Lett (2011) 0.80
Non-proteolytic regulation of p53-mediated transcription through destabilization of the activator.promoter complex by the proteasomal ATPases. J Biol Chem (2009) 0.80
Site-Specific Dual Antibody Conjugation via Engineered Cysteine and Selenocysteine Residues. Bioconjug Chem (2015) 0.80
Direct comparison of linear and macrocyclic compound libraries as a source of protein ligands. ACS Comb Sci (2015) 0.79
On-Bead Two-Color (OBTC) Cell Screen for Direct Identification of Highly Selective Cell Surface Receptor Ligands. Curr Protoc Chem Biol (2012) 0.79
Synthesis of a large library of macrocyclic peptides containing multiple and diverse N-alkylated residues. Mol Biosyst (2015) 0.78
Solid phase synthesis of 1,3,4-oxadiazin-5 (6R)-one and 1,3,4-oxadiazol-2-one scaffolds from acyl hydrazides. Org Biomol Chem (2015) 0.78
Biochemistry: Molecular cloaking devices. Nature (2008) 0.77
Using oxidative crosslinking and proximity labeling to quantitatively characterize protein-protein and protein-Peptide complexes. Chem Biol (2003) 0.77
Reliable diagnosis of murine type 1 diabetes using a panel of autoantigens and "antigen surrogates" mounted onto a liquid array. Mol Biosyst (2015) 0.76
Protein binding: Antibody surrogates click into place. Nat Chem (2009) 0.76
Removal of impurities from transcription factor preparations that alter their DNA-binding properties. Nucleic Acids Res (2002) 0.75
PDZ dimerization brings proteins together. Chem Biol (2011) 0.75
Proteomes take the electrophilic bait. Nat Chem Biol (2008) 0.75
Introduction to monitoring and manipulating signaling networks. Mol Biosyst (2006) 0.75