Published in J Bacteriol on March 01, 1992
Linkage map of Escherichia coli K-12, edition 10: the traditional map. Microbiol Mol Biol Rev (1998) 4.18
Dual response regulators (NarL and NarP) interact with dual sensors (NarX and NarQ) to control nitrate- and nitrite-regulated gene expression in Escherichia coli K-12. J Bacteriol (1993) 2.31
Identification of the regulatory sequence of anaerobically expressed locus aeg-46.5. J Bacteriol (1993) 1.16
The physical map of the whole E. coli chromosome: application of a new strategy for rapid analysis and sorting of a large genomic library. Cell (1987) 46.35
Linkage map of Escherichia coli K-12, edition 8. Microbiol Rev (1990) 18.60
Genomic organization and physical mapping of the transfer RNA genes in Escherichia coli K12. J Mol Biol (1990) 5.43
Alignment of Escherichia coli K12 DNA sequences to a genomic restriction map. Nucleic Acids Res (1990) 4.07
Mapping of sequenced genes (700 kbp) in the restriction map of the Escherichia coli chromosome. Mol Microbiol (1990) 2.90
Purification from Escherichia coli of a periplasmic protein that is a potent inhibitor of pancreatic proteases. J Biol Chem (1983) 1.43
Escherichia coli molecular genetic map (1000 kbp): update I. Mol Microbiol (1990) 1.41
Characterization of a membrane-associated serine protease in Escherichia coli. J Bacteriol (1987) 1.26
The sequence and reactive site of ecotin. A general inhibitor of pancreatic serine proteases from Escherichia coli. J Biol Chem (1991) 1.15
Conversion of alpha-helices into beta-sheets features in the formation of the scrapie prion proteins. Proc Natl Acad Sci U S A (1993) 10.36
Structure and specificity of nuclear receptor-coactivator interactions. Genes Dev (1998) 5.28
Crystal structure of the kinesin motor domain reveals a structural similarity to myosin. Nature (1996) 4.48
Viral cysteine proteases are homologous to the trypsin-like family of serine proteases: structural and functional implications. Proc Natl Acad Sci U S A (1988) 4.32
A structural role for hormone in the thyroid hormone receptor. Nature (1995) 4.27
Structural basis of substrate specificity in the serine proteases. Protein Sci (1995) 4.22
Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein. Proc Natl Acad Sci U S A (1990) 4.12
The design plan of kinesin motors. Annu Rev Cell Dev Biol (1997) 3.79
Redesigning trypsin: alteration of substrate specificity. Science (1985) 3.70
Detection of a trypsin-like serine protease domain in flaviviruses and pestiviruses. Virology (1989) 3.55
Structural clues to prion replication. Science (1994) 3.43
A radioimmunoassay for human prolactin. Proc Natl Acad Sci U S A (1971) 3.36
Crystal structure of the motor domain of the kinesin-related motor ncd. Nature (1996) 3.21
Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries. Proc Natl Acad Sci U S A (2000) 3.06
Replacement of lysine residue 1030 in the putative ATP-binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. Proc Natl Acad Sci U S A (1987) 2.99
Switch-based mechanism of kinesin motors. Nature (2001) 2.86
Splice junctions: association with variation in protein structure. Science (1983) 2.54
Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates. J Biol Chem (2000) 2.50
Synthesis of positional-scanning libraries of fluorogenic peptide substrates to define the extended substrate specificity of plasmin and thrombin. Nat Biotechnol (2000) 2.49
Hormone-dependent coactivator binding to a hydrophobic cleft on nuclear receptors. Science (1998) 2.31
Structure of two related rat pancreatic trypsin genes. J Biol Chem (1984) 2.24
Structural changes in glycogen phosphorylase induced by phosphorylation. Nature (1988) 2.16
Perturbation of the secondary structure of the scrapie prion protein under conditions that alter infectivity. Proc Natl Acad Sci U S A (1993) 2.10
Prolactin and thyrotropin release in man by synthetic pyroglutamyl-histidyl-prolinamide. Biochem Biophys Res Commun (1971) 2.07
Evolutionary divergence of substrate specificity within the chymotrypsin-like serine protease fold. J Biol Chem (1997) 2.05
Reverse biochemistry: use of macromolecular protease inhibitors to dissect complex biological processes and identify a membrane-type serine protease in epithelial cancer and normal tissue. Proc Natl Acad Sci U S A (1999) 2.01
Direction determination in the minus-end-directed kinesin motor ncd. Nature (1998) 1.96
Molecular analysis of GPH1, the gene encoding glycogen phosphorylase in Saccharomyces cerevisiae. Mol Cell Biol (1989) 1.92
The catalytic role of the active site aspartic acid in serine proteases. Science (1987) 1.88
The three-dimensional structure of Asn102 mutant of trypsin: role of Asp102 in serine protease catalysis. Science (1987) 1.87
Clathrin self-assembly is mediated by a tandemly repeated superhelix. Nature (1999) 1.84
Regulation of clathrin assembly and trimerization defined using recombinant triskelion hubs. Cell (1995) 1.80
High-resolution chromosome sorting and DNA spot-blot analysis assign McArdle's syndrome to chromosome 11. Science (1984) 1.80
Medical treatment of Rasmussen's syndrome (chronic encephalitis and epilepsy): effect of high-dose steroids or immunoglobulins in 19 patients. Neurology (1994) 1.79
A model for the microtubule-Ncd motor protein complex obtained by cryo-electron microscopy and image analysis. Cell (1997) 1.79
Defining the level of human immunodeficiency virus type 1 (HIV-1) protease activity required for HIV-1 particle maturation and infectivity. J Virol (1995) 1.78
Molecular cloning and primary structure of human 15-lipoxygenase. Biochem Biophys Res Commun (1988) 1.76
Domain flexibility in retroviral proteases: structural implications for drug resistant mutations. Biochemistry (1998) 1.75
Regulation of autoproteolysis of the HIV-1 and HIV-2 proteases with engineered amino acid substitutions. J Biol Chem (1993) 1.70
Nuclear-receptor ligands and ligand-binding domains. Annu Rev Biochem (1999) 1.70
The family of glycogen phosphorylases: structure and function. Crit Rev Biochem Mol Biol (1989) 1.70
Turn prediction in proteins using a pattern-matching approach. Biochemistry (1986) 1.65
Definition and redesign of the extended substrate specificity of granzyme B. J Biol Chem (1998) 1.65
Intron-exon splice junctions map at protein surfaces. Nature (1982) 1.65
Characterization of globin domains: heme binding to the central exon product. Proc Natl Acad Sci U S A (1980) 1.63
Isolation and sequence of a rat chymotrypsin B gene. J Biol Chem (1984) 1.61
Hydrogen bonds involving sulfur atoms in proteins. Proteins (1991) 1.58
The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi. J Biol Chem (1992) 1.58
Human mast cell tryptase: multiple cDNAs and genes reveal a multigene serine protease family. Proc Natl Acad Sci U S A (1990) 1.55
Prevalence and impact of upper gastrointestinal symptoms in the Canadian population: findings from the DIGEST study. Domestic/International Gastroenterology Surveillance Study. Am J Gastroenterol (1999) 1.54
A plasma kallikrein-dependent plasminogen cascade required for adipocyte differentiation. Nat Cell Biol (2001) 1.51
The exocrine protein trypsinogen is targeted into the secretory granules of an endocrine cell line: studies by gene transfer. J Cell Biol (1985) 1.50
Introduction of a cysteine protease active site into trypsin. Biochemistry (1989) 1.50
The crystal structure of cruzain: a therapeutic target for Chagas' disease. J Mol Biol (1995) 1.49
Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin. Biochemistry (1987) 1.48
The structures and related functions of phosphorylase a. Annu Rev Biochem (1980) 1.48
Evolution of a bifunctional enzyme: 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase. Proc Natl Acad Sci U S A (1989) 1.47
X-ray diffraction of scrapie prion rods and PrP peptides. J Mol Biol (1995) 1.47
Structure-based design of nonpeptide inhibitors specific for the human immunodeficiency virus 1 protease. Proc Natl Acad Sci U S A (1990) 1.46
Three-dimensional structure of a tubulin-motor-protein complex. Nature (1995) 1.46
High resolution x-ray structure of yeast hexokinase, an allosteric protein exhibiting a non-symmetric arrangement of subunits. J Mol Biol (1976) 1.45
A primary determinant for lipoxygenase positional specificity. Nature (1991) 1.45
Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate. Science (1991) 1.44
The case for a common ancestor: kinesin and myosin motor proteins and G proteins. J Muscle Res Cell Motil (1998) 1.44
Structure of the two related elastase genes expressed in the rat pancreas. J Biol Chem (1984) 1.43
Intron/exon structure of the human gene for the muscle isozyme of glycogen phosphorylase. Proteins (1987) 1.42
Two approaches to discovering and developing new drugs for Chagas disease. Mem Inst Oswaldo Cruz (2009) 1.41
Immunologic and proteolytic analysis of HIV-1 reverse transcriptase structure. Virology (1990) 1.38
Purification of human prolactin. J Biol Chem (1972) 1.37
Proposed three-dimensional structure for the cellular prion protein. Proc Natl Acad Sci U S A (1994) 1.35
Immunologic evidence for monkey and human prolactin (MPr and HPr). J Clin Endocrinol Metab (1971) 1.30
Specificity and inhibition of proteases from human immunodeficiency viruses 1 and 2. J Biol Chem (1990) 1.29
Substrate specificity of trypsin investigated by using a genetic selection. Proc Natl Acad Sci U S A (1990) 1.29
Crystal structure of a catalytic antibody with a serine protease active site. Science (1994) 1.29
Human prolactin. Annu Rev Med (1973) 1.28
Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi. J Biol Chem (1993) 1.26
Characterization of the catalytic residues of the tobacco etch virus 49-kDa proteinase. Virology (1989) 1.25
Site-directed mutagenesis shows that tyrosine 248 of carboxypeptidase A does not play a crucial role in catalysis. Nature (1985) 1.25
Viral proteases: evolution of diverse structural motifs to optimize function. Cell (1997) 1.24
Structural determinants of specificity in the cysteine protease cruzain. Protein Sci (1997) 1.24
Amplification and sequencing of genomic DNA fragments encoding cysteine proteases from protozoan parasites. Mol Biochem Parasitol (1990) 1.23
Functional evaluation of prolactin secretion: a guide to therapy. J Clin Invest (1972) 1.22
Perturbing the polar environment of Asp102 in trypsin: consequences of replacing conserved Ser214. Biochemistry (1992) 1.22
Isolation and characterization of a cDNA encoding rat cationic trypsinogen. Biochemistry (1987) 1.22
Expression of cloned human reticulocyte 15-lipoxygenase and immunological evidence that 15-lipoxygenases of different cell types are related. J Biol Chem (1990) 1.21
Parallel evolution in two homologues of phosphorylase. Nat Struct Biol (1994) 1.19
Selective modulation of thyroid hormone receptor action. J Steroid Biochem Mol Biol (2001) 1.18
Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases. Protein Sci (1992) 1.17
Hormone selectivity in thyroid hormone receptors. Mol Endocrinol (2001) 1.17
A novel rat carboxypeptidase, CPA2: characterization, molecular cloning, and evolutionary implications on substrate specificity in the carboxypeptidase gene family. J Biol Chem (1988) 1.17