Published in Curr Opin Genet Dev on October 01, 2004
Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell (2009) 5.43
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. Proc Natl Acad Sci U S A (2005) 3.30
Ten-eleven translocation-2 (TET2) is a master regulator of smooth muscle cell plasticity. Circulation (2013) 2.95
Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol (2005) 2.30
Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol Cell Biol (2005) 2.23
A sonic hedgehog signaling domain in the arterial adventitia supports resident Sca1+ smooth muscle progenitor cells. Proc Natl Acad Sci U S A (2008) 2.05
Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype. Proc Natl Acad Sci U S A (2007) 1.91
Requirement of a myocardin-related transcription factor for development of mammary myoepithelial cells. Mol Cell Biol (2006) 1.89
Requirement of myocardin-related transcription factor-B for remodeling of branchial arch arteries and smooth muscle differentiation. Proc Natl Acad Sci U S A (2005) 1.72
Myocardin-related transcription factor B is required in cardiac neural crest for smooth muscle differentiation and cardiovascular development. Proc Natl Acad Sci U S A (2005) 1.70
Cholesterol loading reprograms the microRNA-143/145-myocardin axis to convert aortic smooth muscle cells to a dysfunctional macrophage-like phenotype. Arterioscler Thromb Vasc Biol (2015) 1.68
PRISM/PRDM6, a transcriptional repressor that promotes the proliferative gene program in smooth muscle cells. Mol Cell Biol (2006) 1.65
Systematic analysis of the transcriptional switch inducing migration of border cells. Dev Cell (2006) 1.63
Acute myeloid leukemia-associated Mkl1 (Mrtf-a) is a key regulator of mammary gland function. Mol Cell Biol (2006) 1.48
Vascular smooth muscle progenitor cells: building and repairing blood vessels. Circ Res (2011) 1.46
CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circ Res (2012) 1.46
Sphingosine-1-phosphate receptor subtypes differentially regulate smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2008) 1.37
Myocardin inhibits cellular proliferation by inhibiting NF-kappaB(p65)-dependent cell cycle progression. Proc Natl Acad Sci U S A (2008) 1.35
Mechanistic basis of Rho GTPase-induced extracellular matrix synthesis in trabecular meshwork cells. Am J Physiol Cell Physiol (2009) 1.24
Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression. Dev Biol (2011) 1.19
microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart. Elife (2013) 1.18
Molecular mechanisms of collagen isotype-specific modulation of smooth muscle cell phenotype. Arterioscler Thromb Vasc Biol (2008) 1.15
The histone trimethyllysine demethylase JMJD2A promotes cardiac hypertrophy in response to hypertrophic stimuli in mice. J Clin Invest (2011) 1.13
Bone morphogenetic protein signaling modulates myocardin transactivation of cardiac genes. Circ Res (2005) 1.09
Protein kinase A-regulated assembly of a MEF2{middle dot}HDAC4 repressor complex controls c-Jun expression in vascular smooth muscle cells. J Biol Chem (2009) 1.08
Myocardin in biology and disease. J Biomed Res (2014) 1.06
CHIP represses myocardin-induced smooth muscle cell differentiation via ubiquitin-mediated proteasomal degradation. Mol Cell Biol (2009) 1.05
Specificity protein-1 as a critical regulator of human cystathionine gamma-lyase in smooth muscle cells. J Biol Chem (2011) 1.03
Synergistic activation of cardiac genes by myocardin and Tbx5. PLoS One (2011) 1.02
Fibroblast growth factor 9 signaling inhibits airway smooth muscle differentiation in mouse lung. Dev Dyn (2009) 0.97
Modulation of pulmonary vascular smooth muscle cell phenotype in hypoxia: role of cGMP-dependent protein kinase and myocardin. Am J Physiol Lung Cell Mol Physiol (2009) 0.97
Sphingosine-1-phosphate receptor-2 regulates expression of smooth muscle alpha-actin after arterial injury. Arterioscler Thromb Vasc Biol (2009) 0.97
A novel RhoA/ROCK-CPI-17-MEF2C signaling pathway regulates vascular smooth muscle cell gene expression. J Biol Chem (2012) 0.96
TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB. Am J Physiol Cell Physiol (2009) 0.95
Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity. Nat Commun (2014) 0.94
Mediator MED23 plays opposing roles in directing smooth muscle cell and adipocyte differentiation. Genes Dev (2012) 0.94
Defining smooth muscle cells and smooth muscle injury. J Clin Invest (2005) 0.92
Disruption of actin cytoskeleton mediates loss of tensile stress induced early phenotypic modulation of vascular smooth muscle cells in organ culture. Exp Mol Pathol (2009) 0.87
Expression of CPI-17 in smooth muscle during embryonic development and in neointimal lesion formation. Histochem Cell Biol (2009) 0.86
Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1 alpha from human mesenchymal stem cells. Exp Mol Med (2010) 0.86
Characterization of zebrafish intestinal smooth muscle development using a novel sm22α-b promoter. Dev Dyn (2010) 0.86
Analysis of gene-environment interactions in postnatal development of the mammalian intestine. Proc Natl Acad Sci U S A (2015) 0.86
Platelet factor 4 mediates vascular smooth muscle cell injury responses. Blood (2013) 0.86
Integrin β1 regulates leiomyoma cytoskeletal integrity and growth. Matrix Biol (2012) 0.85
Do two mutually exclusive gene modules define the phenotypic diversity of mammalian smooth muscle? Mol Genet Genomics (2008) 0.85
Increased myosin light chain kinase expression in hypertension: Regulation by serum response factor via an insertion mutation in the promoter. Mol Biol Cell (2006) 0.84
The cytoskeleton-associated PDZ-LIM protein, ALP, acts on serum response factor activity to regulate muscle differentiation. Mol Biol Cell (2007) 0.83
Myocardin marks the earliest cardiac gene expression and plays an important role in heart development. Anat Rec (Hoboken) (2008) 0.83
Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature. PLoS Genet (2015) 0.82
A bioinformatic and computational study of myosin phosphatase subunit diversity. Am J Physiol Regul Integr Comp Physiol (2014) 0.81
The STARS signaling pathway: a key regulator of skeletal muscle function. Pflugers Arch (2014) 0.81
NPAS1 regulates branching morphogenesis in embryonic lung. Am J Respir Cell Mol Biol (2006) 0.81
Resveratrol induces p53 and suppresses myocardin-mediated vascular smooth muscle cell differentiation. Toxicol Lett (2010) 0.81
Simulations demonstrate a simple network to be sufficient to control branch point selection, smooth muscle and vasculature formation during lung branching morphogenesis. Biol Open (2012) 0.81
A rare human sequence variant reveals myocardin autoinhibition. J Biol Chem (2008) 0.80
Cadherin-11 regulates both mesenchymal stem cell differentiation into smooth muscle cells and the development of contractile function in vivo. J Cell Sci (2014) 0.80
Acetylation of myocardin is required for the activation of cardiac and smooth muscle genes. J Biol Chem (2012) 0.80
SAP domain-dependent Mkl1 signaling stimulates proliferation and cell migration by induction of a distinct gene set indicative of poor prognosis in breast cancer patients. Mol Cancer (2014) 0.80
Vascular smooth muscle cell differentiation-2010. J Biomed Res (2010) 0.79
Motility, survival, and proliferation. Compr Physiol (2012) 0.78
Overexpression of p49/STRAP alters cellular cytoskeletal structure and gross anatomy in mice. BMC Cell Biol (2014) 0.78
The evolutionary origin of bilaterian smooth and striated myocytes. Elife (2016) 0.77
Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol (2016) 0.77
In search of novel targets for heart disease: myocardin and myocardin-related transcriptional cofactors. Biochem Res Int (2012) 0.77
Cooperative activation of cardiac transcription through myocardin bridging of paired MEF2 sites. Development (2017) 0.75
The Role of MicroRNAs in Vascular Diseases; Smooth Muscle Cell Differentiation and De-Differentiation. Korean Circ J (2014) 0.75
Epithelial-to-Pericyte Transition in Cancer. Cancers (Basel) (2017) 0.75
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres. Nature (2002) 14.37
Control of stress-dependent cardiac growth and gene expression by a microRNA. Science (2007) 12.08
A signature pattern of stress-responsive microRNAs that can evoke cardiac hypertrophy and heart failure. Proc Natl Acad Sci U S A (2006) 10.09
Dysregulation of microRNAs after myocardial infarction reveals a role of miR-29 in cardiac fibrosis. Proc Natl Acad Sci U S A (2008) 9.86
The many roles of histone deacetylases in development and physiology: implications for disease and therapy. Nat Rev Genet (2009) 9.68
Transient regenerative potential of the neonatal mouse heart. Science (2011) 9.02
NFAT signaling: choreographing the social lives of cells. Cell (2002) 8.17
The endothelial-specific microRNA miR-126 governs vascular integrity and angiogenesis. Dev Cell (2008) 7.26
Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell (2002) 7.10
MicroRNAs in stress signaling and human disease. Cell (2012) 6.93
Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature (2012) 6.65
Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat Med (2007) 6.61
Cardiac plasticity. N Engl J Med (2008) 6.29
Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer. Genesis (2002) 6.11
Pervasive roles of microRNAs in cardiovascular biology. Nature (2011) 6.08
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell (2004) 5.80
A twist code determines the onset of osteoblast differentiation. Dev Cell (2004) 5.40
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev (2008) 5.39
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performance. Dev Cell (2009) 5.28
MicroRNA-206 delays ALS progression and promotes regeneration of neuromuscular synapses in mice. Science (2009) 5.17
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell (2010) 5.07
Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore. J Clin Invest (2004) 4.97
MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends Biochem Sci (2002) 4.96
Histone deacetylase 5 epigenetically controls behavioral adaptations to chronic emotional stimuli. Neuron (2007) 4.96
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature (2004) 4.76
MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. J Clin Invest (2007) 4.76
Signaling pathways in skeletal muscle remodeling. Annu Rev Biochem (2006) 4.75
Delivery of microRNA-126 by apoptotic bodies induces CXCL12-dependent vascular protection. Sci Signal (2009) 4.73
MEF2: a central regulator of diverse developmental programs. Development (2007) 4.70
Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development (2003) 4.63
MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. Genes Dev (2009) 4.62
Histone deacetylases 1 and 2 redundantly regulate cardiac morphogenesis, growth, and contractility. Genes Dev (2007) 4.50
Protein kinases C and D mediate agonist-dependent cardiac hypertrophy through nuclear export of histone deacetylase 5. Mol Cell Biol (2004) 4.49
Hypertrophy of the heart: a new therapeutic target? Circulation (2004) 4.45
Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad Sci U S A (2003) 4.35
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol Cell Biol (2004) 4.24
The myocardin family of transcriptional coactivators: versatile regulators of cell growth, migration, and myogenesis. Genes Dev (2006) 4.18
Concern Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation (2002) 4.16
Myocardin is a key regulator of CArG-dependent transcription of multiple smooth muscle marker genes. Circ Res (2003) 3.99
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A (2005) 3.78
Potentiation of serum response factor activity by a family of myocardin-related transcription factors. Proc Natl Acad Sci U S A (2002) 3.74
Local InsP3-dependent perinuclear Ca2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest (2006) 3.72
Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell (2010) 3.72
MicroRNAs add a new dimension to cardiovascular disease. Circulation (2010) 3.64
An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proc Natl Acad Sci U S A (2007) 3.62
Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo. Nature (2002) 3.60
CaM kinase II selectively signals to histone deacetylase 4 during cardiomyocyte hypertrophy. J Clin Invest (2006) 3.53
Twist regulates cytokine gene expression through a negative feedback loop that represses NF-kappaB activity. Cell (2003) 3.40
The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2003) 3.40
Mitochondrial deficiency and cardiac sudden death in mice lacking the MEF2A transcription factor. Nat Med (2002) 3.31
Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice. Proc Natl Acad Sci U S A (2005) 3.30
Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo. Proc Natl Acad Sci U S A (2002) 3.27
Control of cardiac growth by histone acetylation/deacetylation. Circ Res (2006) 3.25
Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers. J Clin Invest (2007) 3.19
Toward microRNA-based therapeutics for heart disease: the sense in antisense. Circ Res (2008) 3.18
HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci (2009) 3.18
Reprogramming of human fibroblasts toward a cardiac fate. Proc Natl Acad Sci U S A (2013) 3.14
MicroRNA regulatory networks in cardiovascular development. Dev Cell (2010) 3.09
Histone deacetylase 7 maintains vascular integrity by repressing matrix metalloproteinase 10. Cell (2006) 3.07
Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice. J Clin Invest (2010) 3.04
MicroRNA control of muscle development and disease. Curr Opin Cell Biol (2009) 3.04
MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell (2007) 2.96
MicroRNAs flex their muscles. Trends Genet (2008) 2.94
Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Mol Cell Biol (2002) 2.93
Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons. Development (2007) 2.92
Control of cardiac development by an evolutionarily conserved transcriptional network. Dev Biol (2002) 2.88
Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways. J Clin Invest (2009) 2.82
Hippo pathway effector Yap promotes cardiac regeneration. Proc Natl Acad Sci U S A (2013) 2.76
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling. J Clin Invest (2006) 2.74
Suppression of class I and II histone deacetylases blunts pressure-overload cardiac hypertrophy. Circulation (2006) 2.70
Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family. Proc Natl Acad Sci U S A (2012) 2.66
The delta isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload. Proc Natl Acad Sci U S A (2009) 2.66
MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles. Nat Rev Drug Discov (2012) 2.65
Toward transcriptional therapies for the failing heart: chemical screens to modulate genes. J Clin Invest (2005) 2.65
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (2004) 2.61
Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell (2002) 2.53
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failure. Circulation (2011) 2.52
Unveiling the mechanisms of cell-cell fusion. Science (2005) 2.52
A WW domain protein TAZ is a critical coactivator for TBX5, a transcription factor implicated in Holt-Oram syndrome. Proc Natl Acad Sci U S A (2005) 2.50
Regulation of peroxisome proliferator-activated receptor gamma coactivator 1 alpha (PGC-1 alpha ) and mitochondrial function by MEF2 and HDAC5. Proc Natl Acad Sci U S A (2003) 2.48
Regulation of PI3-kinase/Akt signaling by muscle-enriched microRNA-486. Proc Natl Acad Sci U S A (2010) 2.47
AngiomiRs--key regulators of angiogenesis. Curr Opin Genet Dev (2009) 2.40
Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal (2011) 2.38
Dose-dependent blockade to cardiomyocyte hypertrophy by histone deacetylase inhibitors. J Biol Chem (2003) 2.35
Delta FosB mediates epigenetic desensitization of the c-fos gene after chronic amphetamine exposure. J Neurosci (2008) 2.34
A threshold of GATA4 and GATA6 expression is required for cardiovascular development. Proc Natl Acad Sci U S A (2006) 2.32
MiR-15 family regulates postnatal mitotic arrest of cardiomyocytes. Circ Res (2011) 2.32
Maintenance of cardiac energy metabolism by histone deacetylase 3 in mice. J Clin Invest (2008) 2.31
Renaming the DSCR1/Adapt78 gene family as RCAN: regulators of calcineurin. FASEB J (2007) 2.30
Modulation of smooth muscle gene expression by association of histone acetyltransferases and deacetylases with myocardin. Mol Cell Biol (2005) 2.30
A cardiac microRNA governs systemic energy homeostasis by regulation of MED13. Cell (2012) 2.29
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat Genet (2002) 2.27
Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development. Proc Natl Acad Sci U S A (2009) 2.27
The transcriptional coactivator CAMTA2 stimulates cardiac growth by opposing class II histone deacetylases. Cell (2006) 2.26
Mending broken hearts: cardiac development as a basis for adult heart regeneration and repair. Nat Rev Mol Cell Biol (2013) 2.25
The MEF2D transcription factor mediates stress-dependent cardiac remodeling in mice. J Clin Invest (2008) 2.24
A dynamic notch injury response activates epicardium and contributes to fibrosis repair. Circ Res (2010) 2.23
Muscle-specific signaling mechanism that links actin dynamics to serum response factor. Mol Cell Biol (2005) 2.23
Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases. Cell (2010) 2.22
Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs. Proc Natl Acad Sci U S A (2011) 2.21