Published in Elife on November 19, 2013
Myocardin in biology and disease. J Biomed Res (2014) 1.06
Outside the coding genome, mammalian microRNAs confer structural and functional complexity. Sci Signal (2015) 0.97
Trbp regulates heart function through microRNA-mediated Sox6 repression. Nat Genet (2015) 0.95
Non-Coding RNAs Including miRNAs and lncRNAs in Cardiovascular Biology and Disease. Cells (2014) 0.94
The short and long of noncoding sequences in the control of vascular cell phenotypes. Cell Mol Life Sci (2015) 0.88
Multifaceted roles of miR-1s in repressing the fetal gene program in the heart. Cell Res (2014) 0.88
The RNA-binding protein TDP-43 selectively disrupts microRNA-1/206 incorporation into the RNA-induced silencing complex. J Biol Chem (2014) 0.86
The miR-206/133b cluster is dispensable for development, survival and regeneration of skeletal muscle. Skelet Muscle (2014) 0.86
MicroRNAs and Cardiac Regeneration. Circ Res (2015) 0.86
miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep (2015) 0.85
MYOSLID Is a Novel Serum Response Factor-Dependent Long Noncoding RNA That Amplifies the Vascular Smooth Muscle Differentiation Program. Arterioscler Thromb Vasc Biol (2016) 0.85
miRSeq: a user-friendly standalone toolkit for sequencing quality evaluation and miRNA profiling. Biomed Res Int (2014) 0.83
Cardiac Regeneration: Lessons From Development. Circ Res (2017) 0.82
MicroRNA-1 in Cardiac Diseases and Cancers. Korean J Physiol Pharmacol (2014) 0.82
MicroRNA Mechanisms of Action: What have We Learned from Mice? Front Genet (2015) 0.80
Regulation of Cardiac Cell Fate by microRNAs: Implications for Heart Regeneration. Cells (2014) 0.80
MiRiad Roles for MicroRNAs in Cardiac Development and Regeneration. Cells (2014) 0.80
MicroRNAs get to the heart of development. Elife (2013) 0.78
miR-27 and miR-125 Distinctly Regulate Muscle-Enriched Transcription Factors in Cardiac and Skeletal Myocytes. Biomed Res Int (2015) 0.78
Recent advances in direct cardiac reprogramming. Curr Opin Genet Dev (2015) 0.78
microRNAs and Cardiac Cell Fate. Cells (2014) 0.78
Polymorphism in miRNA-1 target site and circulating miRNA-1 phenotype are associated with the decreased risk and prognosis of coronary artery disease. Int J Clin Exp Pathol (2014) 0.78
Mechanisms and therapeutic potential of microRNAs in hypertension. Drug Discov Today (2015) 0.78
Skeletal Muscle MicroRNAs: Their Diagnostic and Therapeutic Potential in Human Muscle Diseases. J Neuromuscul Dis (2016) 0.78
MiRNA-1/133a clusters regulate adrenergic control of cardiac repolarization. PLoS One (2014) 0.77
Noncoding RNAs in smooth muscle cell homeostasis: implications in phenotypic switch and vascular disorders. Pflugers Arch (2016) 0.77
Non-coding RNAs in muscle differentiation and musculoskeletal disease. J Clin Invest (2016) 0.77
A MicroRNA-Transcription Factor Blueprint for Early Atrial Arrhythmogenic Remodeling. Biomed Res Int (2015) 0.75
The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1. Development (2017) 0.75
Molecular inotropy mediated by cardiac miR-based PDE4D/PRKAR1α/phosphoprotein signaling. Sci Rep (2016) 0.75
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol (2013) 32.42
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature (2005) 17.17
The role of microRNA-1 and microRNA-133 in skeletal muscle proliferation and differentiation. Nat Genet (2005) 17.07
GREAT improves functional interpretation of cis-regulatory regions. Nat Biotechnol (2010) 16.72
Control of translation and mRNA degradation by miRNAs and siRNAs. Genes Dev (2006) 15.20
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature (2009) 10.26
Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors. Cell (1986) 9.10
Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor. Cell (2001) 8.09
Chromatin immunoprecipitation and microarray-based analysis of protein location. Nat Protoc (2006) 7.29
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
Myogenic factors that regulate expression of muscle-specific microRNAs. Proc Natl Acad Sci U S A (2006) 6.19
microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev (2008) 5.39
Myocardin: a component of a molecular switch for smooth muscle differentiation. J Mol Cell Cardiol (2002) 4.92
Making or breaking the heart: from lineage determination to morphogenesis. Cell (2006) 4.85
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J (1987) 4.68
Myocardin is a master regulator of smooth muscle gene expression. Proc Natl Acad Sci U S A (2003) 4.35
Mesodermally expressed Drosophila microRNA-1 is regulated by Twist and is required in muscles during larval growth. Genes Dev (2005) 4.34
Dedicated myosin light chain kinases with diverse cellular functions. J Biol Chem (2000) 3.89
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A (2005) 3.78
An intragenic MEF2-dependent enhancer directs muscle-specific expression of microRNAs 1 and 133. Proc Natl Acad Sci U S A (2007) 3.62
The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A (2003) 3.40
Mutations in either the essential or regulatory light chains of myosin are associated with a rare myopathy in human heart and skeletal muscle. Nat Genet (1996) 3.02
The overall pattern of cardiac contraction depends on a spatial gradient of myosin regulatory light chain phosphorylation. Cell (2001) 2.56
Loss of cardiac microRNA-mediated regulation leads to dilated cardiomyopathy and heart failure. Circ Res (2009) 2.44
MicroRNA regulation of cardiovascular development. Circ Res (2009) 2.42
Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart. Circ Res (2006) 2.36
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med (2011) 2.24
Evidence for serum response factor-mediated regulatory networks governing SM22alpha transcription in smooth, skeletal, and cardiac muscle cells. Dev Biol (1997) 2.23
Control of smooth muscle development by the myocardin family of transcriptional coactivators. Curr Opin Genet Dev (2004) 2.17
GO-Elite: a flexible solution for pathway and ontology over-representation. Bioinformatics (2012) 1.91
Zebrafish miR-1 and miR-133 shape muscle gene expression and regulate sarcomeric actin organization. Genes Dev (2009) 1.84
Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol (2007) 1.77
Dynamic reprogramming of chromatin accessibility during Drosophila embryo development. Genome Biol (2011) 1.61
Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity. J Biol Chem (2002) 1.57
Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro. Nat Med (2000) 1.55
Coactivation of MEF2 by the SAP domain proteins myocardin and MASTR. Mol Cell (2006) 1.54
The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation. Dev Cell (2011) 1.52
Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A (2008) 1.39
Myocardin is differentially required for the development of smooth muscle cells and cardiomyocytes. Am J Physiol Heart Circ Physiol (2011) 1.10
Telokin mediates Ca2+-desensitization through activation of myosin phosphatase in phasic and tonic smooth muscle. J Muscle Res Cell Motil (2005) 1.00
Regulation of myosin light chain kinase and telokin expression in smooth muscle tissues. Am J Physiol Cell Physiol (2006) 0.99
A genome-wide screen reveals a role for microRNA-1 in modulating cardiac cell polarity. Dev Cell (2011) 0.93
Expression and functional activity of four myocardin isoforms. Gene (2010) 0.91
Telokin expression is restricted to smooth muscle tissues during mouse development. Am J Physiol Cell Physiol (2001) 0.90
Alterations in myocardial cytoskeletal and regulatory protein expression following a single Doxorubicin injection. J Cardiovasc Pharmacol (2003) 0.84
Molecular mechanism of telokin-mediated disinhibition of myosin light chain phosphatase and cAMP/cGMP-induced relaxation of gastrointestinal smooth muscle. J Biol Chem (2012) 0.80
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
Serum response factor regulates a muscle-specific microRNA that targets Hand2 during cardiogenesis. Nature (2005) 17.17
Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell (2010) 15.58
A pattern-based method for the identification of MicroRNA binding sites and their corresponding heteroduplexes. Cell (2006) 14.70
Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell (2007) 12.72
Complete MHC haplotype sequencing for common disease gene mapping. Genome Res (2004) 12.09
miR-145 and miR-143 regulate smooth muscle cell fate and plasticity. Nature (2009) 10.26
A conditional knockout resource for the genome-wide study of mouse gene function. Nature (2011) 9.93
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
The amphioxus genome and the evolution of the chordate karyotype. Nature (2008) 8.03
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature (2012) 7.80
The DNA sequence of the human X chromosome. Nature (2005) 6.97
Mutations in a new member of the chromodomain gene family cause CHARGE syndrome. Nat Genet (2004) 6.90
miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59
GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5. Nature (2003) 6.40
Mutations in NOTCH1 cause aortic valve disease. Nature (2005) 6.27
Genome analysis of the platypus reveals unique signatures of evolution. Nature (2008) 5.74
Array-based comparative genomic hybridization for the genomewide detection of submicroscopic chromosomal abnormalities. Am J Hum Genet (2003) 5.43
A physical map of the mouse genome. Nature (2002) 4.97
Thymosin beta4 activates integrin-linked kinase and promotes cardiac cell migration, survival and cardiac repair. Nature (2004) 4.97
Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis. Science (2007) 4.89
A developmental view of microRNA function. Trends Biochem Sci (2007) 4.75
MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell (2008) 4.70
Reciprocal transcriptional regulation of Pou5f1 and Sox2 via the Oct4/Sox2 complex in embryonic stem cells. Mol Cell Biol (2005) 4.54
Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature (2010) 4.38
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project. Immunogenetics (2008) 4.25
Dynamic and coordinated epigenetic regulation of developmental transitions in the cardiac lineage. Cell (2012) 4.22
Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell (2009) 4.21
Comparative and demographic analysis of orang-utan genomes. Nature (2011) 3.83
MicroRNA1 influences cardiac differentiation in Drosophila and regulates Notch signaling. Proc Natl Acad Sci U S A (2005) 3.78
Single-nanowire electrically driven lasers. Nature (2003) 3.69
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia. Cell (2007) 3.58
High-speed graphene transistors with a self-aligned nanowire gate. Nature (2010) 3.48
Versatile P[acman] BAC libraries for transgenesis studies in Drosophila melanogaster. Nat Methods (2009) 3.35
The genome of the green anole lizard and a comparative analysis with birds and mammals. Nature (2011) 3.32
Assessing the impact of comparative genomic sequence data on the functional annotation of the Drosophila genome. Genome Biol (2002) 3.09
The amphioxus genome illuminates vertebrate origins and cephalochordate biology. Genome Res (2008) 3.04
Construction and analysis of a human-chimpanzee comparative clone map. Science (2002) 2.83
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLoS Genet (2006) 2.80
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution. Nat Genet (2013) 2.76
The mammalian gene function resource: the International Knockout Mouse Consortium. Mamm Genome (2012) 2.65
The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner. Development (2004) 2.61
MicroRNAs as regulators of differentiation and cell fate decisions. Cell Stem Cell (2010) 2.57
Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors. Proc Natl Acad Sci U S A (2007) 2.56
Association mapping of local climate-sensitive quantitative trait loci in Arabidopsis thaliana. Proc Natl Acad Sci U S A (2010) 2.51
The antiproliferative action of progesterone in uterine epithelium is mediated by Hand2. Science (2011) 2.46
Evolution of human-specific neural SRGAP2 genes by incomplete segmental duplication. Cell (2012) 2.43
T-cell factor 3 regulates embryonic stem cell pluripotency and self-renewal by the transcriptional control of multiple lineage pathways. Stem Cells (2008) 2.43
MicroRNA regulation of cardiovascular development. Circ Res (2009) 2.42
Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. Hypertension (2004) 2.41
MicroRNA-134 modulates the differentiation of mouse embryonic stem cells, where it causes post-transcriptional attenuation of Nanog and LRH1. Stem Cells (2007) 2.40
Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis. Nat Genet (2012) 2.39
Three-dimensional imaging of dislocations in a nanoparticle at atomic resolution. Nature (2013) 2.37
Natural allelic variation underlying a major fitness trade-off in Arabidopsis thaliana. Nature (2010) 2.34
Noncoding sequences conserved in a limited number of mammals in the SIM2 interval are frequently functional. Genome Res (2004) 2.32
Tembusu virus in ducks, china. Emerg Infect Dis (2011) 2.30
Mining coherent dense subgraphs across massive biological networks for functional discovery. Bioinformatics (2005) 2.28
Bop encodes a muscle-restricted protein containing MYND and SET domains and is essential for cardiac differentiation and morphogenesis. Nat Genet (2002) 2.27
miR-24 inhibits apoptosis and represses Bim in mouse cardiomyocytes. J Exp Med (2011) 2.24
Optimizing the laser-pulse configuration for coherent Raman spectroscopy. Science (2007) 2.24
Graphene nanomesh. Nat Nanotechnol (2010) 2.21
The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell (2005) 2.19
Peroxisome proliferator-activated receptor-γ ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor. Hypertension (2012) 2.16
Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension. Cell Metab (2010) 2.11
High-performance top-gated graphene-nanoribbon transistors using zirconium oxide nanowires as high-dielectric-constant gate dielectrics. Adv Mater (2010) 2.09
Decoding the fine-scale structure of a breast cancer genome and transcriptome. Genome Res (2006) 2.09
Adiponectin-induced endothelial nitric oxide synthase activation and nitric oxide production are mediated by APPL1 in endothelial cells. Diabetes (2007) 2.08
Evolutionary breakpoints in the gibbon suggest association between cytosine methylation and karyotype evolution. PLoS Genet (2009) 2.07
Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. Stem Cell Reports (2013) 2.05
A physical map of the genome of Atlantic salmon, Salmo salar. Genomics (2005) 2.03
Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer. Genes Dev (2003) 2.01
Electrically conductive and optically active porous silicon nanowires. Nano Lett (2009) 2.00
A set of BAC clones spanning the human genome. Nucleic Acids Res (2004) 2.00
A cattle-human comparative map built with cattle BAC-ends and human genome sequence. Genome Res (2003) 1.92
Genetics of human cardiovascular disease. Cell (2012) 1.90
Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol Aging (2008) 1.89
Thymosin beta4 mediated PKC activation is essential to initiate the embryonic coronary developmental program and epicardial progenitor cell activation in adult mice in vivo. J Mol Cell Cardiol (2009) 1.88
Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell (2011) 1.86
A physical map of the chicken genome. Nature (2004) 1.86
DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. Nature (2006) 1.81
microRNA-138 modulates cardiac patterning during embryonic development. Proc Natl Acad Sci U S A (2008) 1.80
Using comparative genomics to reorder the human genome sequence into a virtual sheep genome. Genome Biol (2007) 1.79
Cyclooxygenase-2-derived prostaglandin F2alpha mediates endothelium-dependent contractions in the aortae of hamsters with increased impact during aging. Circ Res (2008) 1.78
Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice. Cardiovasc Res (2007) 1.76
Tbx1 regulates fibroblast growth factors in the anterior heart field through a reinforcing autoregulatory loop involving forkhead transcription factors. Development (2004) 1.75
Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin. Genomics (2002) 1.75
A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate. Nat Cell Biol (2009) 1.73
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells (2009) 1.72
Highly efficient gate-tunable photocurrent generation in vertical heterostructures of layered materials. Nat Nanotechnol (2013) 1.72
Spectrum of heart disease associated with murine and human GATA4 mutation. J Mol Cell Cardiol (2007) 1.71
Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction. Circulation (2008) 1.68
Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors. Cancer Res (2003) 1.67
Notch post-translationally regulates β-catenin protein in stem and progenitor cells. Nat Cell Biol (2011) 1.66