Published in Mol Cell Biol on October 01, 2004
Site-specific release of nascent chains from ribosomes at a sense codon. Mol Cell Biol (2008) 1.73
Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system. Microbiol Mol Biol Rev (2012) 1.48
The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci U S A (2005) 1.43
A comprehensive analysis of translational missense errors in the yeast Saccharomyces cerevisiae. RNA (2010) 1.27
Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast. Mol Biol Cell (2008) 1.18
Differentiating between near- and non-cognate codons in Saccharomyces cerevisiae. PLoS One (2007) 1.17
Nutrient signaling in protein homeostasis: an increase in quantity at the expense of quality. Sci Signal (2013) 1.12
Fuzzy c-means clustering with prior biological knowledge. J Biomed Inform (2008) 1.05
Structural characterization of a eukaryotic chaperone--the ribosome-associated complex. Nat Struct Mol Biol (2012) 1.03
The chaperone network connected to human ribosome-associated complex. Mol Cell Biol (2011) 1.02
Broad sensitivity of Saccharomyces cerevisiae lacking ribosome-associated chaperone ssb or zuo1 to cations, including aminoglycosides. Eukaryot Cell (2005) 1.00
Distinct response of yeast ribosomes to a miscoding event during translation. RNA (2011) 0.96
The Hsp70 homolog Ssb is essential for glucose sensing via the SNF1 kinase network. Genes Dev (2009) 0.95
Release factor eRF3 mediates premature translation termination on polylysine-stalled ribosomes in Saccharomyces cerevisiae. Mol Cell Biol (2014) 0.93
Yeast Uri1p promotes translation initiation and may provide a link to cotranslational quality control. EMBO J (2009) 0.92
Ribosome-associated complex and Ssb are required for translational repression induced by polylysine segments within nascent chains. Mol Cell Biol (2012) 0.90
Fine-tuning of translation termination efficiency in Saccharomyces cerevisiae involves two factors in close proximity to the exit tunnel of the ribosome. Genetics (2007) 0.89
A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replication. J Virol (2010) 0.88
Specific effects of ribosome-tethered molecular chaperones on programmed -1 ribosomal frameshifting. Eukaryot Cell (2006) 0.87
Elongation factor 1A is the target of growth inhibition in yeast caused by Legionella pneumophila glucosyltransferase Lgt1. J Biol Chem (2012) 0.84
A role for the yeast cell cycle/splicing factor Cdc40 in the G1/S transition. Curr Genet (2006) 0.83
Metabolic and chaperone gene loss marks the origin of animals: evidence for Hsp104 and Hsp78 chaperones sharing mitochondrial enzymes as clients. PLoS One (2015) 0.80
Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits. Nat Struct Mol Biol (2016) 0.78
Functional conservation and divergence of J-domain-containing ZUO1/ZRF orthologs throughout evolution. Planta (2014) 0.77
The Not4 RING E3 Ligase: A Relevant Player in Cotranslational Quality Control. ISRN Mol Biol (2013) 0.77
The antibiotic gentamicin inhibits specific protein trafficking functions of the Arf1/2 family of GTPases. Antimicrob Agents Chemother (2010) 0.76
Alleviation of deleterious effects of protein mutation through inactivation of molecular chaperones. Mol Genet Genomics (2008) 0.76
Interaction of the cotranslational Hsp70 Ssb with ribosomal proteins and rRNA depends on its lid domain. Nat Commun (2016) 0.76
A Ribosomopathy Reveals Decoding Defective Ribosomes Driving Human Dysmorphism. Am J Hum Genet (2017) 0.75
How Do J-Proteins Get Hsp70 to Do So Many Different Things? Trends Biochem Sci (2017) 0.75
Multivalent contacts of the Hsp70 Ssb contribute to its architecture on ribosomes and nascent chain interaction. Nat Commun (2016) 0.75
Structural insights into a unique Hsp70-Hsp40 interaction in the eukaryotic ribosome-associated complex. Nat Struct Mol Biol (2017) 0.75
Two chaperones locked in an embrace: structure and function of the ribosome-associated complex RAC. Nat Struct Mol Biol (2017) 0.75
Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem (1987) 59.79
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene (1988) 42.65
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. Mol Gen Genet (1984) 35.54
The complete atomic structure of the large ribosomal subunit at 2.4 A resolution. Science (2000) 28.25
New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae. Yeast (1994) 24.57
Multifunctional yeast high-copy-number shuttle vectors. Gene (1992) 19.47
Molecular chaperones in the cytosol: from nascent chain to folded protein. Science (2002) 15.09
A yeast prion provides a mechanism for genetic variation and phenotypic diversity. Nature (2000) 6.65
Selection of tRNA by the ribosome requires a transition from an open to a closed form. Cell (2002) 5.62
Immunochemical identification of membrane proteins after sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Methods Enzymol (1983) 4.58
The translation machinery and 70 kd heat shock protein cooperate in protein synthesis. Cell (1992) 4.39
Kinetic determinants of high-fidelity tRNA discrimination on the ribosome. Mol Cell (2004) 3.40
Nonsense-mediated decay mutants do not affect programmed -1 frameshifting. RNA (2000) 3.13
Nascent membrane and secretory proteins differ in FRET-detected folding far inside the ribosome and in their exposure to ribosomal proteins. Cell (2004) 3.03
Phenotypic suppression and misreading Saccharomyces cerevisiae. Nature (1979) 3.01
Fidelity of aminoacyl-tRNA selection on the ribosome: kinetic and structural mechanisms. Annu Rev Biochem (2001) 2.97
FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A (1991) 2.97
Insights into the decoding mechanism from recent ribosome structures. Trends Biochem Sci (2003) 2.71
Phenotypic suppression of nonsense mutants in yeast by aminoglycoside antibiotics. Nature (1979) 2.66
Translational accuracy and the fitness of bacteria. Annu Rev Genet (1992) 2.56
Evidence for a protein mutator in yeast: role of the Hsp70-related chaperone ssb in formation, stability, and toxicity of the [PSI] prion. Mol Cell Biol (1999) 2.37
The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides. Mol Cell Biol (2003) 2.36
Mechanism of prion loss after Hsp104 inactivation in yeast. Mol Cell Biol (2001) 2.27
Versatile vectors to study recoding: conservation of rules between yeast and mammalian cells. Nucleic Acids Res (1995) 2.17
The molecular chaperone Ssb from Saccharomyces cerevisiae is a component of the ribosome-nascent chain complex. EMBO J (1998) 2.17
Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics. EMBO J (1994) 2.08
Paromomycin binding induces a local conformational change in the A-site of 16 S rRNA. J Mol Biol (1998) 2.06
RAC, a stable ribosome-associated complex in yeast formed by the DnaK-DnaJ homologs Ssz1p and zuotin. Proc Natl Acad Sci U S A (2001) 1.94
The polypeptide tunnel system in the ribosome and its gating in erythromycin resistance mutants of L4 and L22. Mol Cell (2001) 1.94
Basis for prokaryotic specificity of action of aminoglycoside antibiotics. EMBO J (1999) 1.91
Structure and replication of yeast prions. Cell (1998) 1.91
Impact of the six nucleotides downstream of the stop codon on translation termination. EMBO Rep (2001) 1.88
Zuotin, a ribosome-associated DnaJ molecular chaperone. EMBO J (1998) 1.84
The involvement of two distinct regions of 23 S ribosomal RNA in tRNA selection. J Mol Biol (1995) 1.74
Nascent polypeptide-associated complex stimulates protein import into yeast mitochondria. Mol Biol Cell (1999) 1.69
A functional chaperone triad on the yeast ribosome. Proc Natl Acad Sci U S A (2002) 1.63
Yeast ribosomal protein L24 affects the kinetics of protein synthesis and ribosomal protein L39 improves translational accuracy, while mutants lacking both remain viable. Biochemistry (2000) 1.61
An accuracy center in the ribosome conserved over 2 billion years. Proc Natl Acad Sci U S A (1993) 1.60
Altered 40 S ribosomal subunits in omnipotent suppressors of yeast. J Mol Biol (1986) 1.60
Misreading of the ribosomal suppressor SUP46 due to an altered 40 S subunit in yeast. J Mol Biol (1981) 1.49
The in vivo function of the ribosome-associated Hsp70, Ssz1, does not require its putative peptide-binding domain. Proc Natl Acad Sci U S A (2002) 1.48
Identification of stop codon readthrough genes in Saccharomyces cerevisiae. Nucleic Acids Res (2003) 1.42
Yeast glycosylation mutants are sensitive to aminoglycosides. Proc Natl Acad Sci U S A (1995) 1.39
Retracted TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes. EMBO J (2003) 1.38
Prions of yeast as heritable amyloidoses. J Struct Biol (2000) 1.37
Ribosome-tethered molecular chaperones: the first line of defense against protein misfolding? Curr Opin Microbiol (2003) 1.35
Conformational changes in the ribosome induced by translational miscoding agents. J Mol Biol (2000) 1.33
Major rearrangements in the 70S ribosomal 3D structure caused by a conformational switch in 16S ribosomal RNA. EMBO J (1999) 1.32
Missense translation errors in Saccharomyces cerevisiae. J Mol Biol (1998) 1.32
Maintenance and inheritance of yeast prions. Trends Genet (1996) 1.29
Mutational disruption of plasma membrane trafficking of Saccharomyces cerevisiae Yor1p, a homologue of mammalian multidrug resistance protein. Mol Cell Biol (1999) 1.26
Regulation of transcription factor Pdr1p function by an Hsp70 protein in Saccharomyces cerevisiae. Mol Cell Biol (1998) 1.17
In vitro protein translocation across microsomal membranes of Saccharomyces cerevisiae. Methods Enzymol (1991) 1.08
Mutations in yeast ribosomal proteins S28 and S4 affect the accuracy of translation and alter the sensitivity of the ribosomes to paromomycin. Biochim Biophys Acta (1996) 1.05
Isolation and characterization of omnipotent suppressors in the yeast Saccharomyces cerevisiae. Genetics (1990) 1.01
Ribosome function: governing the fate of a nascent polypeptide. Curr Biol (2004) 1.01
Structural dynamics of ribosomal RNA during decoding on the ribosome. Biochimie (2002) 0.96
Deletion of the Hsp70 chaperone gene SSB causes hypersensitivity to guanidine toxicity and curing of the [PSI+] prion by increasing guanidine uptake in yeast. Mol Genet Genomics (2003) 0.96
The utility of prions. Dev Cell (2002) 0.96
Isolation of omnipotent suppressors in an [eta+] yeast strain. Genetics (1990) 0.94
The role of active site residue arginine 218 in firefly luciferase bioluminescence. Biochemistry (2001) 0.91
Identification of a role for actin in translational fidelity in yeast. Mol Genet Genomics (2002) 0.88
The growth of mdp1/rsp5 mutants of Saccharomyces cerevisiae is affected by mutations in the ATP-binding domain of the plasma membrane H+ -ATPase. Gene (2000) 0.84
Ribosomal dynamics inferred from variations in experimental measurements. RNA (2003) 0.83
Prion-dependent switching between respiratory competence and deficiency in the yeast nam9-1 mutant. Mol Cell Biol (2000) 0.80
Differential antibiotic sensitivity determined by the large ribosomal subunit in thermophilic archaea. J Bacteriol (1996) 0.77
Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature (2003) 3.46
Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell (2011) 2.52
The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides. Mol Cell Biol (2003) 2.36
The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1. Nat Struct Mol Biol (2005) 2.28
A functional chaperone triad on the yeast ribosome. Proc Natl Acad Sci U S A (2002) 1.63
A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel. Proc Natl Acad Sci U S A (2009) 1.49
Transcriptional activation of polycomb-repressed genes by ZRF1. Nature (2010) 1.44
The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci U S A (2005) 1.43
Identification of the signal directing Tim9 and Tim10 into the intermembrane space of mitochondria. Mol Biol Cell (2009) 1.41
Association of protein biogenesis factors at the yeast ribosomal tunnel exit is affected by the translational status and nascent polypeptide sequence. J Biol Chem (2007) 1.35
Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast. Mol Biol Cell (2008) 1.18
Functional characterization of the atypical Hsp70 subunit of yeast ribosome-associated complex. J Biol Chem (2007) 1.03
The chaperone network connected to human ribosome-associated complex. Mol Cell Biol (2011) 1.02
NAC functions as a modulator of SRP during the early steps of protein targeting to the endoplasmic reticulum. Mol Biol Cell (2012) 0.96
The Hsp70 homolog Ssb is essential for glucose sensing via the SNF1 kinase network. Genes Dev (2009) 0.95
The ribosome-bound Hsp70 homolog Ssb of Saccharomyces cerevisiae. Biochim Biophys Acta (2010) 0.92
Ribosome-associated complex and Ssb are required for translational repression induced by polylysine segments within nascent chains. Mol Cell Biol (2012) 0.90
A targeted analysis of cellular chaperones reveals contrasting roles for heat shock protein 70 in flock house virus RNA replication. J Virol (2010) 0.88
Carbon monoxide releasing molecule-2 CORM-2 represses global protein synthesis by inhibition of eukaryotic elongation factor eEF2. Int J Biochem Cell Biol (2012) 0.86
Interaction of nascent chains with the ribosomal tunnel proteins Rpl4, Rpl17, and Rpl39 of Saccharomyces cerevisiae. J Biol Chem (2013) 0.86
Elongation factor 1A is the target of growth inhibition in yeast caused by Legionella pneumophila glucosyltransferase Lgt1. J Biol Chem (2012) 0.84
Aminoacyl-tRNA-charged eukaryotic elongation factor 1A is the bona fide substrate for Legionella pneumophila effector glucosyltransferases. PLoS One (2011) 0.81
BiP modulates the affinity of its co-chaperone ERj1 for ribosomes. J Biol Chem (2010) 0.78
Molecular chaperones and intracellular protein transport. Biochim Biophys Acta (2010) 0.75