Published in Nature on December 23, 2010
Transcriptional regulation by Polycomb group proteins. Nat Struct Mol Biol (2013) 2.96
Unfolding of the C-terminal domain of the J-protein Zuo1 releases autoinhibition and activates Pdr1-dependent transcription. J Mol Biol (2012) 2.04
Roles of the Polycomb group proteins in stem cells and cancer. Cell Death Dis (2011) 1.70
Jarid1b targets genes regulating development and is involved in neural differentiation. EMBO J (2011) 1.50
Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci (2015) 1.43
Targeting polycomb to pericentric heterochromatin in embryonic stem cells reveals a role for H2AK119u1 in PRC2 recruitment. Cell Rep (2014) 1.43
Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet (2012) 1.40
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nat Struct Mol Biol (2012) 1.30
Lysine-targeting specificity in ubiquitin and ubiquitin-like modification pathways. Nat Struct Mol Biol (2014) 1.16
ZRF1 mediates remodeling of E3 ligases at DNA lesion sites during nucleotide excision repair. J Cell Biol (2016) 1.12
Polycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila. Mol Cell Biol (2012) 1.10
TRIM37 is a new histone H2A ubiquitin ligase and breast cancer oncoprotein. Nature (2014) 1.09
The chaperone network connected to human ribosome-associated complex. Mol Cell Biol (2011) 1.02
Pluripotency and Epigenetic Factors in Mouse Embryonic Stem Cell Fate Regulation. Mol Cell Biol (2015) 0.95
Shaping the landscape: mechanistic consequences of ubiquitin modification of chromatin. EMBO Rep (2012) 0.94
Release factor eRF3 mediates premature translation termination on polylysine-stalled ribosomes in Saccharomyces cerevisiae. Mol Cell Biol (2014) 0.93
Ribosome-associated complex and Ssb are required for translational repression induced by polylysine segments within nascent chains. Mol Cell Biol (2012) 0.90
Role for the molecular chaperones Zuo1 and Ssz1 in quorum sensing via activation of the transcription factor Pdr1. Proc Natl Acad Sci U S A (2011) 0.88
Dual role of Med12 in PRC1-dependent gene repression and ncRNA-mediated transcriptional activation. Cell Cycle (2016) 0.86
A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation. PLoS Genet (2014) 0.86
Histone monoubiquitylation position determines specificity and direction of enzymatic cross-talk with histone methyltransferases Dot1L and PRC2. J Biol Chem (2012) 0.85
BMI1-RING1B is an autoinhibited RING E3 ubiquitin ligase. Nat Commun (2015) 0.84
Zrf1 is required to establish and maintain neural progenitor identity. Genes Dev (2014) 0.84
DNAJs: more than substrate delivery to HSPA. Front Mol Biosci (2015) 0.84
Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. Elife (2015) 0.83
HSCARG, a novel regulator of H2A ubiquitination by downregulating PRC1 ubiquitin E3 ligase activity, is essential for cell proliferation. Nucleic Acids Res (2014) 0.82
ZRF1: a novel epigenetic regulator of stem cell identity and cancer. Cell Cycle (2015) 0.78
Identification of AMP-activated protein kinase targets by a consensus sequence search of the proteome. BMC Syst Biol (2015) 0.78
Dual interaction of the Hsp70 J-protein cochaperone Zuotin with the 40S and 60S ribosomal subunits. Nat Struct Mol Biol (2016) 0.78
ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J (2017) 0.78
Functional conservation and divergence of J-domain-containing ZUO1/ZRF orthologs throughout evolution. Planta (2014) 0.77
Direct interaction between Id1 and Zrf1 controls neural differentiation of embryonic stem cells. EMBO Rep (2014) 0.77
Zrf1 controls mesoderm lineage genes and cardiomyocyte differentiation. Cell Cycle (2016) 0.76
Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells. Mol Cell Proteomics (2016) 0.76
Polycomb meets mediator to balance pluripotency and differentiation. Cell Cycle (2016) 0.75
Epigenetic Modulation of Stem Cells in Neurodevelopment: The Role of Methylation and Acetylation. Front Cell Neurosci (2017) 0.75
Autoantibody Response to ZRF1 and KRR1 SEREX Antigens in Patients with Breast Tumors of Different Histological Types and Grades. Dis Markers (2016) 0.75
The BRCA1 Ubiquitin ligase function sets a new trend for remodelling in DNA repair. Nucleus (2016) 0.75
Timing of DNA lesion recognition: Ubiquitin Signalling in the NER pathway. Cell Cycle (2016) 0.75
ZRF1 Chromatin Regulators Have Polycomb Silencing and Independent Roles in Development. Plant Physiol (2016) 0.75
Two chaperones locked in an embrace: structure and function of the ribosome-associated complex RAC. Nat Struct Mol Biol (2017) 0.75
Role of remodeling and spacing factor 1 in histone H2A ubiquitination-mediated gene silencing. Proc Natl Acad Sci U S A (2017) 0.75
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc (2009) 137.99
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res (1983) 124.30
Chromatin modifications and their function. Cell (2007) 55.98
The language of covalent histone modifications. Nature (2000) 44.92
The role of chromatin during transcription. Cell (2007) 26.48
Polycomb complexes repress developmental regulators in murine embryonic stem cells. Nature (2006) 25.90
Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions. Genes Dev (2006) 14.36
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein. Genes Dev (2002) 13.08
Role of histone H2A ubiquitination in Polycomb silencing. Nature (2004) 9.48
The polycomb group protein Suz12 is required for embryonic stem cell differentiation. Mol Cell Biol (2007) 8.57
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science (2007) 7.41
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell (2009) 6.89
Ubiquitin-binding domains. Nat Rev Mol Cell Biol (2005) 6.77
A DNA integrity network in the yeast Saccharomyces cerevisiae. Cell (2006) 6.61
Loss of the cylindromatosis tumour suppressor inhibits apoptosis by activating NF-kappaB. Nature (2003) 6.53
Retinoic acid induces neuronal differentiation of a cloned human embryonal carcinoma cell line in vitro. Dev Biol (1984) 4.16
Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation. Mol Cell (2005) 4.04
Pluripotent embryonal carcinoma clones derived from the human teratocarcinoma cell line Tera-2. Differentiation in vivo and in vitro. Lab Invest (1984) 3.86
Genome-wide analysis of KAP1 binding suggests autoregulation of KRAB-ZNFs. PLoS Genet (2007) 3.75
Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the Drosophila genome. Cell (1982) 3.28
Histone H2A monoubiquitination represses transcription by inhibiting RNA polymerase II transcriptional elongation. Mol Cell (2008) 3.18
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell (2007) 3.16
dKDM2 couples histone H2A ubiquitylation to histone H3 demethylation during Polycomb group silencing. Genes Dev (2008) 2.29
Isolation and characterization of protein A24, a "histone-like" non-histone chromosomal protein. J Biol Chem (1975) 1.91
Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation. Genes Dev (2008) 1.87
Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization. Genome Biol (2005) 1.80
Ubiquitinated histone H2B is preferentially located in transcriptionally active chromatin. Biochemistry (1989) 1.44
The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci U S A (2005) 1.43
Genome-wide uH2A localization analysis highlights Bmi1-dependent deposition of the mark at repressed genes. PLoS Genet (2009) 1.36
Characterization of several leukemia-associated antigens inducing humoral immune responses in acute and chronic myeloid leukemia. Int J Cancer (2003) 1.03
MIDA1, an Id-associating protein, has two distinct DNA binding activities that are converted by the association with Id1: a novel function of Id protein. Biochem Biophys Res Commun (1999) 0.94
Haptoglobin-beta chain defined by monoclonal antibody RM2 as a novel serum marker for prostate cancer. Int J Cancer (2008) 0.89
A putative oncogenic role for MPP11 in head and neck squamous cell cancer. Cancer Res (2000) 0.89
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project. Nature (2007) 75.09
The Polycomb group protein EZH2 directly controls DNA methylation. Nature (2005) 13.67
Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination. Science (2007) 7.41
Clinical and biological implications of driver mutations in myelodysplastic syndromes. Blood (2013) 6.50
A large-scale full-length cDNA analysis to explore the budding yeast transcriptome. Proc Natl Acad Sci U S A (2006) 5.24
Comprehensive identification of mutational cancer driver genes across 12 tumor types. Sci Rep (2013) 3.92
IntOGen: integration and data mining of multidimensional oncogenomic data. Nat Methods (2010) 3.63
Machinery for protein sorting and assembly in the mitochondrial outer membrane. Nature (2003) 3.46
Role of the polycomb repressive complex 2 in acute promyelocytic leukemia. Cancer Cell (2007) 3.16
BioMart Central Portal: an open database network for the biological community. Database (Oxford) (2011) 3.03
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics. Mol Cell Biol (2007) 3.03
The origin of planetary impactors in the inner solar system. Science (2005) 3.01
SNP and haplotype mapping for genetic analysis in the rat. Nat Genet (2008) 2.96
Functional impact bias reveals cancer drivers. Nucleic Acids Res (2012) 2.96
Myc represses transcription through recruitment of DNA methyltransferase corepressor. EMBO J (2004) 2.94
Gitools: analysis and visualisation of genomic data using interactive heat-maps. PLoS One (2011) 2.74
A crucial role for adipose tissue p53 in the regulation of insulin resistance. Nat Med (2009) 2.65
Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor. Mol Cell Biol (2008) 2.57
A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q. Genome Res (2004) 2.56
Dual role of mitofilin in mitochondrial membrane organization and protein biogenesis. Dev Cell (2011) 2.52
Identification of Ser-386 of interferon regulatory factor 3 as critical target for inducible phosphorylation that determines activation. J Biol Chem (2003) 2.45
The yeast N(alpha)-acetyltransferase NatA is quantitatively anchored to the ribosome and interacts with nascent polypeptides. Mol Cell Biol (2003) 2.36
The circadian molecular clock creates epidermal stem cell heterogeneity. Nature (2011) 2.34
The Hsp70 Ssz1 modulates the function of the ribosome-associated J-protein Zuo1. Nat Struct Mol Biol (2005) 2.28
Living donor liver transplantation: the Asian perspective. Transplantation (2014) 2.13
Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell (2012) 2.11
IntOGen-mutations identifies cancer drivers across tumor types. Nat Methods (2013) 2.10
RYBP and Cbx7 define specific biological functions of polycomb complexes in mouse embryonic stem cells. Cell Rep (2012) 2.03
Landscape of somatic mutations and clonal evolution in mantle cell lymphoma. Proc Natl Acad Sci U S A (2013) 2.00
Computational disease gene identification: a concert of methods prioritizes type 2 diabetes and obesity candidate genes. Nucleic Acids Res (2006) 1.95
OncodriveCLUST: exploiting the positional clustering of somatic mutations to identify cancer genes. Bioinformatics (2013) 1.90
Retracted The chromatin-remodeling complex WINAC targets a nuclear receptor to promoters and is impaired in Williams syndrome. Cell (2003) 1.88
Deubiquitylation of histone H2A activates transcriptional initiation via trans-histone cross-talk with H3K4 di- and trimethylation. Genes Dev (2008) 1.87
Single center experience of 39 patients with preoperative portal vein thrombosis among 404 adult living donor liver transplantations. Liver Transpl (2006) 1.81
High-resolution DNA methylome analysis of primordial germ cells identifies gender-specific reprogramming in mice. Genome Res (2013) 1.75
Brain-derived neurotrophic factor protects against cardiac dysfunction after myocardial infarction via a central nervous system-mediated pathway. Arterioscler Thromb Vasc Biol (2012) 1.75
The histone variant macroH2A is an epigenetic regulator of key developmental genes. Nat Struct Mol Biol (2009) 1.75
Retracted Lysyl oxidase-like 2 deaminates lysine 4 in histone H3. Mol Cell (2012) 1.74
Meningitis-retention syndrome. An unrecognized clinical condition. J Neurol (2005) 1.72
Polycomb complexes in stem cells and embryonic development. Development (2013) 1.67
Computational approaches to identify functional genetic variants in cancer genomes. Nat Methods (2013) 1.64
A functional chaperone triad on the yeast ribosome. Proc Natl Acad Sci U S A (2002) 1.63
Living donor liver transplantation with reduced monosegments for neonates and small infants. Transplantation (2007) 1.61
Chromatin-bound IκBα regulates a subset of polycomb target genes in differentiation and cancer. Cancer Cell (2013) 1.61
Amplification-free whole-genome bisulfite sequencing by post-bisulfite adaptor tagging. Nucleic Acids Res (2012) 1.61
Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation. Proc Natl Acad Sci U S A (2003) 1.59
Mouse oocyte methylomes at base resolution reveal genome-wide accumulation of non-CpG methylation and role of DNA methyltransferases. PLoS Genet (2013) 1.57
Hemoperfusion with a high-mobility group box 1 adsorption column can prevent the occurrence of hepatic ischemia-reperfusion injury in rats. Crit Care Med (2010) 1.51
Nucleosomal histone kinase-1 phosphorylates H2A Thr 119 during mitosis in the early Drosophila embryo. Genes Dev (2004) 1.49
A histone chaperone, DEK, transcriptionally coactivates a nuclear receptor. Genes Dev (2009) 1.49
A signal-anchor sequence stimulates signal recognition particle binding to ribosomes from inside the exit tunnel. Proc Natl Acad Sci U S A (2009) 1.49
Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia. Blood (2007) 1.48
Living donor liver transplantation as a second-line therapeutic strategy for patients with hepatocellular carcinoma. Liver Transpl (2006) 1.48
Survival in nonocclusive mesenteric ischemia: early diagnosis by multidetector row computed tomography and early treatment with continuous intravenous high-dose prostaglandin E(1). Ann Surg (2007) 1.47
Loss of dE2F compromises mitochondrial function. Dev Cell (2013) 1.47
Barrier proteins remodel and modify chromatin to restrict silenced domains. Mol Cell Biol (2004) 1.47
Regulation of human epidermal stem cell proliferation and senescence requires polycomb- dependent and -independent functions of Cbx4. Cell Stem Cell (2011) 1.45
Living-donor liver transplantation with monosegments. Transplantation (2003) 1.45
Sox9 and p300 cooperatively regulate chromatin-mediated transcription. J Biol Chem (2005) 1.44
Proteomic analysis of in vivo 14-3-3 interactions in the yeast Saccharomyces cerevisiae. Biochemistry (2007) 1.43
PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis. Bioinformatics (2012) 1.43
Linker histone variants control chromatin dynamics during early embryogenesis. Proc Natl Acad Sci U S A (2005) 1.43
The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex. Proc Natl Acad Sci U S A (2005) 1.43
The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase. EMBO J (2002) 1.41
The conserved kinase NHK-1 is essential for mitotic progression and unifying acentrosomal meiotic spindles in Drosophila melanogaster. J Cell Biol (2005) 1.41
Identification of the signal directing Tim9 and Tim10 into the intermembrane space of mitochondria. Mol Biol Cell (2009) 1.41
Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2. J Biol Chem (2003) 1.41
Structure and function of the PB1 domain, a protein interaction module conserved in animals, fungi, amoebas, and plants. Sci STKE (2007) 1.41
Discovery of the first insect nidovirus, a missing evolutionary link in the emergence of the largest RNA virus genomes. PLoS Pathog (2011) 1.40
Histone H2A mono-ubiquitination is a crucial step to mediate PRC1-dependent repression of developmental genes to maintain ES cell identity. PLoS Genet (2012) 1.40
Long-term outcome and metastatic risk after endoscopic resection of superficial esophageal squamous cell carcinoma. Am J Gastroenterol (2013) 1.39
MBD3, a component of the NuRD complex, facilitates chromatin alteration and deposition of epigenetic marks. Mol Cell Biol (2008) 1.36
Association of protein biogenesis factors at the yeast ribosomal tunnel exit is affected by the translational status and nascent polypeptide sequence. J Biol Chem (2007) 1.35
The resurgence of Coulter counting for analyzing nanoscale objects. Analyst (2004) 1.33
In vivo characterization of bone marrow-derived fibroblasts recruited into fibrotic lesions. Stem Cells (2005) 1.31
Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Mol Cell Biol (2002) 1.31
Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity. Nat Struct Mol Biol (2012) 1.30
A histone code in meiosis: the histone kinase, NHK-1, is required for proper chromosomal architecture in Drosophila oocytes. Genes Dev (2005) 1.30
DNA methylation of the gonadal aromatase (cyp19a) promoter is involved in temperature-dependent sex ratio shifts in the European sea bass. PLoS Genet (2011) 1.30
Crystal structure of aminopeptidase N (proteobacteria alanyl aminopeptidase) from Escherichia coli and conformational change of methionine 260 involved in substrate recognition. J Biol Chem (2006) 1.28
The Watanabe heritable hyperlipidemic (WHHL) rabbit, its characteristics and history of development: a tribute to the late Dr. Yoshio Watanabe. Atherosclerosis (2009) 1.28
Methionine adenosyltransferase II serves as a transcriptional corepressor of Maf oncoprotein. Mol Cell (2011) 1.28
Regulation of histone acetylation and nucleosome assembly by transcription factor JDP2. Nat Struct Mol Biol (2006) 1.27
Podoplanin-positive fibroblasts enhance lung adenocarcinoma tumor formation: podoplanin in fibroblast functions for tumor progression. Cancer Res (2011) 1.26
Integrative cancer genomics (IntOGen) in Biomart. Database (Oxford) (2011) 1.26
Whole genome analysis of p38 SAPK-mediated gene expression upon stress. BMC Genomics (2010) 1.25
Absolute quantification of the budding yeast transcriptome by means of competitive PCR between genomic and complementary DNAs. BMC Genomics (2008) 1.24
Atrogin-1 ubiquitin ligase is upregulated by doxorubicin via p38-MAP kinase in cardiac myocytes. Cardiovasc Res (2008) 1.22
Development of an animal model for spontaneous myocardial infarction (WHHLMI rabbit). Arterioscler Thromb Vasc Biol (2003) 1.20
Transcriptional activators in yeast. Nucleic Acids Res (2006) 1.20
Small-for-size graft in living donor liver transplantation: how far should we go? Liver Transpl (2003) 1.19
The ribosome-bound chaperones RAC and Ssb1/2p are required for accurate translation in Saccharomyces cerevisiae. Mol Cell Biol (2004) 1.19
Molecular recognition in dimerization between PB1 domains. J Biol Chem (2003) 1.18
Ribosome-associated complex binds to ribosomes in close proximity of Rpl31 at the exit of the polypeptide tunnel in yeast. Mol Biol Cell (2008) 1.18
Usefulness of the Kyoto criteria as expanded selection criteria for liver transplantation for hepatocellular carcinoma. Surgery (2013) 1.17
The methyl-CpG binding protein MBD1 is required for PML-RARalpha function. Proc Natl Acad Sci U S A (2006) 1.17
Outcomes of adult-to-adult living donor liver transplantation: a single institution's experience with 335 consecutive cases. Ann Surg (2007) 1.15