Published in J Biol Chem on October 12, 2004
Septins regulate actin organization and cell-cycle arrest through nuclear accumulation of NCK mediated by SOCS7. Cell (2007) 2.36
Some assembly required: yeast septins provide the instruction manual. Trends Cell Biol (2005) 1.96
Positive selection, relaxation, and acceleration in the evolution of the human and chimp genome. PLoS Comput Biol (2006) 1.95
Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility. Nat Cell Biol (2008) 1.88
Mammalian septins regulate microtubule stability through interaction with the microtubule-binding protein MAP4. Mol Biol Cell (2005) 1.75
Here come the septins: novel polymers that coordinate intracellular functions and organization. J Cell Sci (2006) 1.60
GTP-induced conformational changes in septins and implications for function. Proc Natl Acad Sci U S A (2009) 1.35
SEPT9 occupies the terminal positions in septin octamers and mediates polymerization-dependent functions in abscission. J Cell Biol (2011) 1.22
Septins regulate bacterial entry into host cells. PLoS One (2009) 1.16
Septin 9 isoform expression, localization and epigenetic changes during human and mouse breast cancer progression. Breast Cancer Res (2011) 1.13
Septin functions in organ system physiology and pathology. Biol Chem (2014) 1.10
Septin 14 is involved in cortical neuronal migration via interaction with Septin 4. Mol Biol Cell (2010) 1.07
Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4. Mol Cell Biol (2005) 1.07
A draft of the human septin interactome. PLoS One (2010) 1.06
Septin 11 is present in GABAergic synapses and plays a functional role in the cytoarchitecture of neurons and GABAergic synaptic connectivity. J Biol Chem (2009) 1.02
Septin 11 restricts InlB-mediated invasion by Listeria. J Biol Chem (2009) 1.02
Superfluous role of mammalian septins 3 and 5 in neuronal development and synaptic transmission. Mol Cell Biol (2008) 1.00
SEPT9 gene sequencing analysis reveals recurrent mutations in hereditary neuralgic amyotrophy. Neurology (2009) 0.98
Septin 7 forms a complex with CD2AP and nephrin and regulates glucose transporter trafficking. Mol Biol Cell (2012) 0.93
High SEPT9_v1 Expression Is Associated with Poor Clinical Outcomes in Head and Neck Squamous Cell Carcinoma. Transl Oncol (2010) 0.92
Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain. BMC Neurosci (2012) 0.91
Matrix stiffness regulates endothelial cell proliferation through septin 9. PLoS One (2012) 0.89
The role of the septin family in spermiogenesis. Spermatogenesis (2011) 0.89
SEPTIN12 genetic variants confer susceptibility to teratozoospermia. PLoS One (2012) 0.87
Dma/RNF8 proteins are evolutionarily conserved E3 ubiquitin ligases that target septins. Cell Cycle (2013) 0.87
The expression pattern of SEPT7 correlates with sperm morphology. J Assist Reprod Genet (2010) 0.87
Identification of a PDZ protein, PIST, as a binding partner for Rho effector Rhotekin: biochemical and cell-biological characterization of Rhotekin-PIST interaction. Biochem J (2006) 0.87
Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration. Mol Neurodegener (2011) 0.84
A loss of function analysis of host factors influencing Vaccinia virus replication by RNA interference. PLoS One (2014) 0.82
Sept7b is essential for pronephric function and development of left-right asymmetry in zebrafish embryogenesis. J Cell Sci (2014) 0.81
Forchlorfenuron disrupts SEPT9_i1 filaments and inhibits HIF-1. PLoS One (2013) 0.80
Duplication within the SEPT9 gene associated with a founder effect in North American families with hereditary neuralgic amyotrophy. Hum Mol Genet (2009) 0.80
SEPT12/SPAG4/LAMINB1 complexes are required for maintaining the integrity of the nuclear envelope in postmeiotic male germ cells. PLoS One (2015) 0.79
Septin expression in proliferative retinal membranes. J Histochem Cytochem (2007) 0.78
GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis. Sci Rep (2016) 0.77
Undressing a cellular corset: septins exposed. Nat Cell Biol (2009) 0.76
Proteomic analysis of cellular soluble proteins from human bronchial smooth muscle cells by combining nondenaturing micro 2DE and quantitative LC-MS/MS. 2. Similarity search between protein maps for the analysis of protein complexes. Electrophoresis (2015) 0.75
Heterotypic Coiled-Coil Formation is Essential for the Correct Assembly of the Septin Heterofilament. Biophys J (2016) 0.75
Localization of septin proteins in the mouse cochlea. Hear Res (2012) 0.75
Structural and Thermodynamic Properties of Septin 3 Investigated by Small-Angle X-Ray Scattering. Biophys J (2015) 0.75
The Mammalian Septin Interactome. Front Cell Dev Biol (2017) 0.75
Septin 9_i2 is downregulated in tumors, impairs cancer cell migration and alters subnuclear actin filaments. Sci Rep (2017) 0.75
Interaction of Recombinant Gallus gallus SEPT5 and Brain Proteins of H5N1-Avian Influenza Virus-Infected Chickens. Proteomes (2017) 0.75
Phosphorylation by aurora B converts MgcRacGAP to a RhoGAP during cytokinesis. Dev Cell (2003) 2.54
Complex formation of Plk1 and INCENP required for metaphase-anaphase transition. Nat Cell Biol (2005) 2.41
Aurora-B phosphorylates Histone H3 at serine28 with regard to the mitotic chromosome condensation. Genes Cells (2002) 2.28
Effects of miR-34a on cell growth and chemoresistance in prostate cancer PC3 cells. Biochem Biophys Res Commun (2008) 2.08
Autophosphorylation of a newly identified site of Aurora-B is indispensable for cytokinesis. J Biol Chem (2004) 1.97
Filament formation of MSF-A, a mammalian septin, in human mammary epithelial cells depends on interactions with microtubules. J Biol Chem (2003) 1.82
Mitochondrial haplogroup N9a confers resistance against type 2 diabetes in Asians. Am J Hum Genet (2007) 1.76
PKCepsilon-mediated phosphorylation of vimentin controls integrin recycling and motility. EMBO J (2005) 1.75
MiR-148a attenuates paclitaxel resistance of hormone-refractory, drug-resistant prostate cancer PC3 cells by regulating MSK1 expression. J Biol Chem (2010) 1.66
Vimentin organization modulates the formation of lamellipodia. Mol Biol Cell (2011) 1.60
MicroRNA-141 and -200a are involved in bone morphogenetic protein-2-induced mouse pre-osteoblast differentiation by targeting distal-less homeobox 5. J Biol Chem (2009) 1.59
Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones. Mol Cell Biol (2005) 1.56
Inhibition of cortactin and SIRT1 expression attenuates migration and invasion of prostate cancer DU145 cells. Int J Urol (2011) 1.56
A role for SIRT1 in cell growth and chemoresistance in prostate cancer PC3 and DU145 cells. Biochem Biophys Res Commun (2008) 1.52
Role of phosphorylation on the structural dynamics and function of types III and IV intermediate filaments. Exp Cell Res (2007) 1.52
Barrier-to-autointegration factor plays crucial roles in cell cycle progression and nuclear organization in Drosophila. J Cell Sci (2003) 1.50
Assessment of the genetic component of hypertension. Am J Hypertens (2006) 1.47
Aurora-B regulates the cleavage furrow-specific vimentin phosphorylation in the cytokinetic process. J Biol Chem (2002) 1.47
MiR-34a attenuates paclitaxel-resistance of hormone-refractory prostate cancer PC3 cells through direct and indirect mechanisms. Prostate (2010) 1.44
Association of a polymorphism of the phospholipase D2 gene with the prevalence of colorectal cancer. J Mol Med (Berl) (2003) 1.37
Xanthones induce cell-cycle arrest and apoptosis in human colon cancer DLD-1 cells. Bioorg Med Chem (2005) 1.36
Regulatory mechanisms and functions of intermediate filaments: a study using site- and phosphorylation state-specific antibodies. Cancer Sci (2006) 1.35
Phosphorylation by Cdk1 induces Plk1-mediated vimentin phosphorylation during mitosis. J Cell Biol (2005) 1.34
Preferential target is mitochondria in alpha-mangostin-induced apoptosis in human leukemia HL60 cells. Bioorg Med Chem (2004) 1.33
Characterized mechanism of alpha-mangostin-induced cell death: caspase-independent apoptosis with release of endonuclease-G from mitochondria and increased miR-143 expression in human colorectal cancer DLD-1 cells. Bioorg Med Chem (2007) 1.33
Anti-cancer effects of xanthones from pericarps of mangosteen. Int J Mol Sci (2008) 1.30
High expression of sphingosine kinase 1 and S1P receptors in chemotherapy-resistant prostate cancer PC3 cells and their camptothecin-induced up-regulation. Biochem Biophys Res Commun (2006) 1.29
MAP kinase-mediated phosphorylation of distinct pools of histone H3 at S10 or S28 via mitogen- and stress-activated kinase 1/2. J Cell Sci (2005) 1.29
Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. Biochem Biophys Res Commun (2009) 1.27
Densin-180 interacts with delta-catenin/neural plakophilin-related armadillo repeat protein at synapses. J Biol Chem (2001) 1.25
Phosphorylation and reorganization of vimentin by p21-activated kinase (PAK). Genes Cells (2002) 1.22
Cytoskeletal modification of Rho guanine nucleotide exchange factor activity: identification of a Rho guanine nucleotide exchange factor as a binding partner for Sept9b, a mammalian septin. Oncogene (2005) 1.22
Genetic risk for ischemic and hemorrhagic stroke. Arterioscler Thromb Vasc Biol (2006) 1.21
Prediction of genetic risk for metabolic syndrome. Atherosclerosis (2006) 1.20
Vimentin rearrangement during African swine fever virus infection involves retrograde transport along microtubules and phosphorylation of vimentin by calcium calmodulin kinase II. J Virol (2005) 1.17
Protein phosphatase 4 catalytic subunit regulates Cdk1 activity and microtubule organization via NDEL1 dephosphorylation. J Cell Biol (2008) 1.17
Novel positive feedback loop between Cdk1 and Chk1 in the nucleus during G2/M transition. J Biol Chem (2009) 1.17
Identification of CELSR1 as a susceptibility gene for ischemic stroke in Japanese individuals by a genome-wide association study. Atherosclerosis (2009) 1.17
Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation. J Biol Chem (2009) 1.17
Riluzole enhances expression of brain-derived neurotrophic factor with consequent proliferation of granule precursor cells in the rat hippocampus. FASEB J (2002) 1.12
Regulation of mitotic function of Chk1 through phosphorylation at novel sites by cyclin-dependent kinase 1 (Cdk1). Genes Cells (2006) 1.12
B plexins activate Rho through PDZ-RhoGEF. FEBS Lett (2002) 1.11
Women with mitochondrial haplogroup N9a are protected against metabolic syndrome. Diabetes (2007) 1.11
Induction of apoptosis by xanthones from mangosteen in human leukemia cell lines. J Nat Prod (2003) 1.11
DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. PLoS One (2010) 1.10
Antitumor effect of resveratrol oligomers against human cancer cell lines and the molecular mechanism of apoptosis induced by vaticanol C. Carcinogenesis (2003) 1.10
Regulation of sphingosine kinase 1 gene expression by protein kinase C in a human leukemia cell line, MEG-O1. Biochim Biophys Acta (2003) 1.09
Arsenic trioxide-induced apoptosis and its enhancement by buthionine sulfoximine in hepatocellular carcinoma cell lines. Biochem Biophys Res Commun (2002) 1.09
Biochemical and cell biological characterization of a mammalian septin, Sept11. FEBS Lett (2004) 1.09
Possible role of Rho/Rhotekin signaling in mammalian septin organization. Oncogene (2005) 1.08
Calcium/calmodulin-dependent protein kinase II (CaMKII) localization acts in concert with substrate targeting to create spatial restriction for phosphorylation. J Biol Chem (2004) 1.08
Cell growth inhibitory effect of cinnamic acid derivatives from propolis on human tumor cell lines. Biol Pharm Bull (2003) 1.07
Aurora-B and Rho-kinase/ROCK, the two cleavage furrow kinases, independently regulate the progression of cytokinesis: possible existence of a novel cleavage furrow kinase phosphorylates ezrin/radixin/moesin (ERM). Genes Cells (2005) 1.07
Disruption of Sept6, a fusion partner gene of MLL, does not affect ontogeny, leukemogenesis induced by MLL-SEPT6, or phenotype induced by the loss of Sept4. Mol Cell Biol (2005) 1.07
Sirtuin 1 overexpression mice show a reference memory deficit, but not neuroprotection. Biochem Biophys Res Commun (2009) 1.06
Cytotoxic benzophenone derivatives from Garcinia species display a strong apoptosis-inducing effect against human leukemia cell lines. Biol Pharm Bull (2003) 1.05
Vascular smooth muscle cell polyploidization involves changes in chromosome passenger proteins and an endomitotic cell cycle. Exp Cell Res (2005) 1.05
Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome. Int J Mol Med (2008) 1.05
Assessment of genetic risk for myocardial infarction. Thromb Haemost (2006) 1.04
14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage. EMBO J (2010) 1.04
SEPT9 sequence alternations causing hereditary neuralgic amyotrophy are associated with altered interactions with SEPT4/SEPT11 and resistance to Rho/Rhotekin-signaling. Hum Mutat (2007) 1.03
Production of a site- and phosphorylation state-specific antibody. Nat Protoc (2007) 1.03
Withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis. J Biol Chem (2010) 1.03
Trichoplein and Aurora A block aberrant primary cilia assembly in proliferating cells. J Cell Biol (2012) 1.03
Trichoplein controls microtubule anchoring at the centrosome by binding to Odf2 and ninein. J Cell Sci (2011) 1.02
Association of a polymorphism of BTN2A1 with myocardial infarction in East Asian populations. Atherosclerosis (2010) 1.02
Tumor necrosis factor alpha-induced interleukin-8 production via NF-kappaB and phosphatidylinositol 3-kinase/Akt pathways inhibits cell apoptosis in human hepatocytes. Infect Immun (2002) 1.01
Functional significance of the specific sites phosphorylated in desmin at cleavage furrow: Aurora-B may phosphorylate and regulate type III intermediate filaments during cytokinesis coordinatedly with Rho-kinase. Mol Biol Cell (2003) 1.01
Molecular hydrogen inhibits lipopolysaccharide/interferon γ-induced nitric oxide production through modulation of signal transduction in macrophages. Biochem Biophys Res Commun (2011) 1.01
The keratin-binding protein Albatross regulates polarization of epithelial cells. J Cell Biol (2008) 0.99
Cell cycle progression by the repression of primary cilia formation in proliferating cells. Cell Mol Life Sci (2013) 0.99
Effects of propolis on cell growth and gene expression in HL-60 cells. J Ethnopharmacol (2005) 0.98
A novel protein, densin, expressed by glomerular podocytes. J Am Soc Nephrol (2003) 0.98
Lifespan-extending effects of royal jelly and its related substances on the nematode Caenorhabditis elegans. PLoS One (2011) 0.97
Vimentin intermediate filament reorganization by Cdc42: involvement of PAK and p70 S6 kinase. Eur J Cell Biol (2002) 0.97
Identification of trichoplein, a novel keratin filament-binding protein. J Cell Sci (2005) 0.97
Identification of caffeoylquinic acid derivatives from Brazilian propolis as constituents involved in induction of granulocytic differentiation of HL-60 cells. Bioorg Med Chem (2005) 0.97
Catalytic inactivation of human phospholipase D2 by a naturally occurring Gly901Asp mutation. Arch Med Res (2006) 0.97
P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation. Mol Biol Cell (2012) 0.96
Mitochondrial haplogroup A is a genetic risk factor for atherothrombotic cerebral infarction in Japanese females. Mitochondrion (2006) 0.96
Genetic factors for lone atrial fibrillation. Int J Mol Med (2007) 0.96
Mitochondrial haplogroup N9b is protective against myocardial infarction in Japanese males. Hum Genet (2006) 0.96
Densin-180, a synaptic protein, links to PSD-95 through its direct interaction with MAGUIN-1. Genes Cells (2002) 0.95
Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42. J Biol Chem (2007) 0.95
An autocrine/paracrine loop linking keratin 14 aggregates to tumor necrosis factor alpha-mediated cytotoxicity in a keratinocyte model of epidermolysis bullosa simplex. J Biol Chem (2003) 0.95
Cisplatin induces production of reactive oxygen species via NADPH oxidase activation in human prostate cancer cells. Free Radic Res (2011) 0.94
Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin. Biochim Biophys Acta (2009) 0.94
Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons. Neurosci Res (2006) 0.94
Association of genetic variants with chronic kidney disease in Japanese individuals. Clin J Am Soc Nephrol (2009) 0.93
Nuclear Chk1 prevents premature mitotic entry. J Cell Sci (2011) 0.93
Interaction of a multi-domain adaptor protein, vinexin, with a Rho-effector, Rhotekin. Med Mol Morphol (2009) 0.92
Prediction of genetic risk for dyslipidemia. Genomics (2007) 0.92
Expression of the NF-kappa B target gene X-ray-inducible immediate early response factor-1 short enhances TNF-alpha-induced hepatocyte apoptosis by inhibiting Akt activation. J Immunol (2003) 0.92
Antitumor effect of arsenic trioxide in murine xenograft model. Cancer Sci (2003) 0.92
Preconditioning by sesquiterpene lactone enhances H2O2-induced Nrf2/ARE activation. Biochem Biophys Res Commun (2008) 0.92
Association of genetic variants with myocardial infarction in Japanese individuals with metabolic syndrome. Atherosclerosis (2009) 0.92
Characterization of a multidomain adaptor protein, p140Cap, as part of a pre-synaptic complex. J Neurochem (2008) 0.91
A potent apoptosis-inducing activity of a sesquiterpene lactone, arucanolide, in HL60 cells: a crucial role of apoptosis-inducing factor. J Pharmacol Sci (2005) 0.91
Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cells. Biochem J (2003) 0.91