Published in Biotechnol Bioeng on November 05, 2004
Silk as a Biomaterial. Prog Polym Sci (2007) 4.13
In vivo degradation of three-dimensional silk fibroin scaffolds. Biomaterials (2008) 3.39
Sonication-induced gelation of silk fibroin for cell encapsulation. Biomaterials (2007) 2.15
Engineering adipose-like tissue in vitro and in vivo utilizing human bone marrow and adipose-derived mesenchymal stem cells with silk fibroin 3D scaffolds. Biomaterials (2007) 2.13
Engineering cartilage tissue. Adv Drug Deliv Rev (2007) 2.08
The knee meniscus: structure-function, pathophysiology, current repair techniques, and prospects for regeneration. Biomaterials (2011) 1.91
Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue. J Biomed Mater Res A (2008) 1.63
Bone tissue engineering with premineralized silk scaffolds. Bone (2008) 1.43
Macromer density influences mesenchymal stem cell chondrogenesis and maturation in photocrosslinked hyaluronic acid hydrogels. Osteoarthritis Cartilage (2009) 1.43
Tissue engineering of functional articular cartilage: the current status. Cell Tissue Res (2011) 1.29
Mandibular repair in rats with premineralized silk scaffolds and BMP-2-modified bMSCs. Biomaterials (2009) 1.29
Biomaterials approach to expand and direct differentiation of stem cells. Mol Ther (2007) 1.24
Collagen scaffolds populated with human marrow stromal cells reduce lesion volume and improve functional outcome after traumatic brain injury. Neurosurgery (2007) 1.24
Stem cell- and scaffold-based tissue engineering approaches to osteochondral regenerative medicine. Semin Cell Dev Biol (2009) 1.21
Multilayered silk scaffolds for meniscus tissue engineering. Biomaterials (2010) 1.18
Spatial regulation of human mesenchymal stem cell differentiation in engineered osteochondral constructs: effects of pre-differentiation, soluble factors and medium perfusion. Osteoarthritis Cartilage (2010) 1.09
Porous silk scaffolds can be used for tissue engineering annulus fibrosus. Eur Spine J (2007) 1.09
Apatite-coated silk fibroin scaffolds to healing mandibular border defects in canines. Bone (2009) 1.03
Effects of chondrogenic and osteogenic regulatory factors on composite constructs grown using human mesenchymal stem cells, silk scaffolds and bioreactors. J R Soc Interface (2008) 1.01
Physical stimulation of chondrogenic cells in vitro: a review. Clin Orthop Relat Res (2011) 1.00
Reinforcing silk scaffolds with silk particles. Macromol Biosci (2010) 0.98
Multivalent protein polymer MRI contrast agents: controlling relaxivity via modulation of amino acid sequence. Biomacromolecules (2010) 0.94
Engineering cartilage and bone using human mesenchymal stem cells. J Orthop Sci (2007) 0.89
Protein polymer MRI contrast agents: Longitudinal analysis of biomaterials in vivo. Magn Reson Med (2011) 0.88
Remodeling of tissue-engineered bone structures in vivo. Eur J Pharm Biopharm (2013) 0.87
Neural network analysis identifies scaffold properties necessary for in vitro chondrogenesis in elastin-like polypeptide biopolymer scaffolds. Tissue Eng Part A (2010) 0.87
Treatment of traumatic brain injury in mice with bone marrow stromal cell-impregnated collagen scaffolds. J Neurosurg (2009) 0.83
The treatment of TBI with human marrow stromal cells impregnated into collagen scaffold: functional outcome and gene expression profile. Brain Res (2010) 0.83
Influence of the mechanical environment on the engineering of mineralised tissues using human dental pulp stem cells and silk fibroin scaffolds. PLoS One (2014) 0.82
Sensate scaffolds can reliably detect joint loading. J Biomed Mater Res B Appl Biomater (2007) 0.81
Laminar silk scaffolds for aligned tissue fabrication. Macromol Biosci (2012) 0.80
Multifunctionalized electrospun silk fibers promote axon regeneration in central nervous system. Adv Funct Mater (2011) 0.80
Synergistic effects of hypoxia and morphogenetic factors on early chondrogenic commitment of human embryonic stem cells in embryoid body culture. Stem Cell Rev (2015) 0.80
In vitro chondrogenic differentiation of human adipose-derived stem cells with silk scaffolds. J Tissue Eng (2012) 0.79
Preparation of porous scaffolds from silk fibroin extracted from the silk gland of Bombyx mori (B. mori). Int J Mol Sci (2012) 0.78
Growth factor and ultrasound-assisted bioreactor synergism for human mesenchymal stem cell chondrogenesis. J Tissue Eng (2015) 0.78
A 3D Porous Gelatin-Alginate-Based-IPN Acts as an Efficient Promoter of Chondrogenesis from Human Adipose-Derived Stem Cells. Stem Cells Int (2015) 0.78
Transdermal delivery devices: fabrication, mechanics and drug release from silk. Small (2013) 0.78
Role of Cartilage Forming Cells in Regenerative Medicine for Cartilage Repair. Orthop Res Rev (2010) 0.77
High-resolution NMR characterization of a spider-silk mimetic composed of 15 tandem repeats and a CRGD motif. Protein Sci (2009) 0.77
Development of a silk and collagen fiber scaffold for anterior cruciate ligament reconstruction. J Mater Sci Mater Med (2012) 0.76
Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytes. Osteoarthritis Cartilage (2013) 0.76
Deciphering mechanical regulation of chondrogenesis in fibrin-polyurethane composite scaffolds enriched with human mesenchymal stem cells: a dual computational and experimental approach. Tissue Eng Part A (2014) 0.75
Scaffold structure and fabrication method affect proinflammatory milieu in three-dimensional-cultured chondrocytes. J Biomed Mater Res A (2014) 0.75
A biphasic scaffold based on silk and bioactive ceramic with stratified properties for osteochondral tissue regeneration. J Mater Chem B Mater Biol Med (2015) 0.75
Fabrication of Innovative Silk/Alginate Microcarriers for Mesenchymal Stem Cell Delivery and Tissue Regeneration. Int J Mol Sci (2017) 0.75
Electrospun silk fibroin-gelatin composite tubular matrices as scaffolds for small diameter blood vessel regeneration. J Mater Sci Mater Med (2017) 0.75
Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol (2007) 17.80
Knocking down barriers: advances in siRNA delivery. Nat Rev Drug Discov (2009) 12.46
Engineering vascularized skeletal muscle tissue. Nat Biotechnol (2005) 7.73
Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials (2005) 7.55
Targeted nanoparticle-aptamer bioconjugates for cancer chemotherapy in vivo. Proc Natl Acad Sci U S A (2006) 6.90
Impact of nanotechnology on drug delivery. ACS Nano (2009) 6.87
A combinatorial library of lipid-like materials for delivery of RNAi therapeutics. Nat Biotechnol (2008) 6.81
Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci U S A (2006) 6.66
Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile. Sci Transl Med (2012) 5.92
Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells. Nat Biotechnol (2004) 5.51
Transdermal drug delivery. Nat Biotechnol (2008) 5.11
TAp73 knockout shows genomic instability with infertility and tumor suppressor functions. Genes Dev (2008) 4.85
Adipose tissue mass can be regulated through the vasculature. Proc Natl Acad Sci U S A (2002) 4.77
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc Natl Acad Sci U S A (2008) 4.57
Nanoparticle-aptamer bioconjugates: a new approach for targeting prostate cancer cells. Cancer Res (2004) 4.56
Combined postmenopausal hormone therapy and cardiovascular disease: toward resolving the discrepancy between observational studies and the Women's Health Initiative clinical trial. Am J Epidemiol (2005) 4.55
Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nat Biotechnol (2008) 4.46
A tough biodegradable elastomer. Nat Biotechnol (2002) 4.35
Lipid-like materials for low-dose, in vivo gene silencing. Proc Natl Acad Sci U S A (2010) 4.25
Functional assembly of engineered myocardium by electrical stimulation of cardiac myocytes cultured on scaffolds. Proc Natl Acad Sci U S A (2004) 4.13
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials (2006) 4.09
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis. J Gene Med (2005) 4.04
Accordion-like honeycombs for tissue engineering of cardiac anisotropy. Nat Mater (2008) 4.00
A reversibly switching surface. Science (2003) 3.97
Therapeutic siRNA silencing in inflammatory monocytes in mice. Nat Biotechnol (2011) 3.95
Small-scale systems for in vivo drug delivery. Nat Biotechnol (2003) 3.90
Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers. Proc Natl Acad Sci U S A (2008) 3.80
Nanoparticle delivery of cancer drugs. Annu Rev Med (2011) 3.75
Endothelial cells derived from human embryonic stem cells. Proc Natl Acad Sci U S A (2002) 3.66
Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA-PEG nanoparticles. Proc Natl Acad Sci U S A (2008) 3.62
First-in-human testing of a wirelessly controlled drug delivery microchip. Sci Transl Med (2012) 3.56
Controlled degradation and mechanical behavior of photopolymerized hyaluronic acid networks. Biomacromolecules (2005) 3.44
Current status and future potential of transdermal drug delivery. Nat Rev Drug Discov (2004) 3.41
Oncomodulin is a macrophage-derived signal for axon regeneration in retinal ganglion cells. Nat Neurosci (2006) 3.35
Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells. Proc Natl Acad Sci U S A (2002) 3.35
Treating metastatic cancer with nanotechnology. Nat Rev Cancer (2011) 3.30
Hyaluronic acid hydrogel for controlled self-renewal and differentiation of human embryonic stem cells. Proc Natl Acad Sci U S A (2007) 3.19
Outbreak of adverse reactions associated with contaminated heparin. N Engl J Med (2008) 3.16
Nanotechnological strategies for engineering complex tissues. Nat Nanotechnol (2010) 3.15
Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells. Nat Mater (2010) 3.11
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery. Nat Nanotechnol (2012) 3.09
Engineering substrate topography at the micro- and nanoscale to control cell function. Angew Chem Int Ed Engl (2009) 3.09
Stem cell-based tissue engineering with silk biomaterials. Biomaterials (2006) 2.88
Microengineered hydrogels for tissue engineering. Biomaterials (2007) 2.87
Differentiation of human embryonic stem cells on three-dimensional polymer scaffolds. Proc Natl Acad Sci U S A (2003) 2.86
Semi-automated synthesis and screening of a large library of degradable cationic polymers for gene delivery. Angew Chem Int Ed Engl (2003) 2.83
The inflammatory responses to silk films in vitro and in vivo. Biomaterials (2005) 2.79
Biodegradable, elastic shape-memory polymers for potential biomedical applications. Science (2002) 2.79
Self-assembled lipid--polymer hybrid nanoparticles: a robust drug delivery platform. ACS Nano (2008) 2.76
Nanomedicine: developing smarter therapeutic and diagnostic modalities. Adv Drug Deliv Rev (2006) 2.69
Multi-pulse drug delivery from a resorbable polymeric microchip device. Nat Mater (2003) 2.65
A combinatorial polymer library approach yields insight into nonviral gene delivery. Acc Chem Res (2008) 2.63
A biodegradable and biocompatible gecko-inspired tissue adhesive. Proc Natl Acad Sci U S A (2008) 2.58
Macroporous nanowire nanoelectronic scaffolds for synthetic tissues. Nat Mater (2012) 2.57
Cell differentiation by mechanical stress. FASEB J (2001) 2.56
Engineering complex tissues. Tissue Eng (2006) 2.53
Light-induced shape-memory polymers. Nature (2005) 2.52
Risk of cardiovascular disease by hysterectomy status, with and without oophorectomy: the Women's Health Initiative Observational Study. Circulation (2005) 2.49
Engineered microenvironments for controlled stem cell differentiation. Tissue Eng Part A (2009) 2.48
Medium perfusion enables engineering of compact and contractile cardiac tissue. Am J Physiol Heart Circ Physiol (2003) 2.42
Quantum dot-aptamer conjugates for synchronous cancer imaging, therapy, and sensing of drug delivery based on bi-fluorescence resonance energy transfer. Nano Lett (2007) 2.40
A vector-free microfluidic platform for intracellular delivery. Proc Natl Acad Sci U S A (2013) 2.40
Development of lipidoid-siRNA formulations for systemic delivery to the liver. Mol Ther (2009) 2.39
An aptamer-doxorubicin physical conjugate as a novel targeted drug-delivery platform. Angew Chem Int Ed Engl (2006) 2.38
Bio-inspired polymer composite actuator and generator driven by water gradients. Science (2013) 2.38
Engineering anatomically shaped human bone grafts. Proc Natl Acad Sci U S A (2009) 2.37
Nanotechnology in drug delivery and tissue engineering: from discovery to applications. Nano Lett (2010) 2.35
Controlling size, shape and homogeneity of embryoid bodies using poly(ethylene glycol) microwells. Lab Chip (2007) 2.30
Biocompatibility and biofouling of MEMS drug delivery devices. Biomaterials (2003) 2.27
Bone tissue engineering using human mesenchymal stem cells: effects of scaffold material and medium flow. Ann Biomed Eng (2004) 2.26
Endothelialized microvasculature based on a biodegradable elastomer. Tissue Eng (2005) 2.23
Silk implants for the healing of critical size bone defects. Bone (2005) 2.22
PLGA-lecithin-PEG core-shell nanoparticles for controlled drug delivery. Biomaterials (2008) 2.21
Number sense growth in kindergarten: a longitudinal investigation of children at risk for mathematics difficulties. Child Dev (2006) 2.21
Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proc Natl Acad Sci U S A (2010) 2.21
A longitudinal study of mathematical competencies in children with specific mathematics difficulties versus children with comorbid mathematics and reading difficulties. Child Dev (2003) 2.20
Biomimetic approach to cardiac tissue engineering: oxygen carriers and channeled scaffolds. Tissue Eng (2006) 2.20
Composite scaffold provides a cell delivery platform for cardiovascular repair. Proc Natl Acad Sci U S A (2011) 2.14
Micromolding of shape-controlled, harvestable cell-laden hydrogels. Biomaterials (2006) 2.12
Nanostructured materials for applications in drug delivery and tissue engineering. J Biomater Sci Polym Ed (2007) 2.12
Vascular progenitor cells isolated from human embryonic stem cells give rise to endothelial and smooth muscle like cells and form vascular networks in vivo. Circ Res (2007) 2.12
Progress in tissue engineering. Sci Am (2009) 2.08
In vivo engineering of organs: the bone bioreactor. Proc Natl Acad Sci U S A (2005) 2.04