Published in Atherosclerosis on November 01, 2004
Whitehall II - Social and Occupational Influences On Health and Illness | NCT00005680
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Am J Hum Genet (2009) 2.04
Interactions between life stress factors and carrying the APOE4 allele adversely impact self-reported health in old adults. J Gerontol A Biol Sci Med Sci (2011) 0.86
A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease. Atherosclerosis (2014) 0.77
Association of APOE gene polymorphism with lipid profile and coronary artery disease in Afro-Caribbeans. PLoS One (2017) 0.75
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25
Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet (2012) 11.09
Job strain as a risk factor for coronary heart disease: a collaborative meta-analysis of individual participant data. Lancet (2012) 9.43
Prediabetes: a high-risk state for diabetes development. Lancet (2012) 6.42
Identification of seven new prostate cancer susceptibility loci through a genome-wide association study. Nat Genet (2009) 6.04
Gender-specific associations of short sleep duration with prevalent and incident hypertension: the Whitehall II Study. Hypertension (2007) 5.20
Trajectories of glycaemia, insulin sensitivity, and insulin secretion before diagnosis of type 2 diabetes: an analysis from the Whitehall II study. Lancet (2009) 4.96
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis. Lancet (2012) 4.87
A prospective study of change in sleep duration: associations with mortality in the Whitehall II cohort. Sleep (2007) 4.25
Inequalities in non-communicable diseases and effective responses. Lancet (2013) 4.18
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility. Nat Genet (2014) 4.13
The UK10K project identifies rare variants in health and disease. Nature (2015) 3.89
Use of low-density lipoprotein cholesterol gene score to distinguish patients with polygenic and monogenic familial hypercholesterolaemia: a case-control study. Lancet (2013) 3.87
Subjective social status: its determinants and its association with measures of ill-health in the Whitehall II study. Soc Sci Med (2003) 3.79
Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: consensus statement of the European Atherosclerosis Society. Eur Heart J (2013) 3.58
Sickness absence as a global measure of health: evidence from mortality in the Whitehall II prospective cohort study. BMJ (2003) 3.54
A person based formula for allocating commissioning funds to general practices in England: development of a statistical model. BMJ (2011) 3.46
Does subjective social status predict health and change in health status better than objective status? Psychosom Med (2005) 3.15
Correlates of short and long sleep duration: a cross-cultural comparison between the United Kingdom and the United States: the Whitehall II Study and the Western New York Health Study. Am J Epidemiol (2008) 3.11
A review on the diagnosis, natural history, and treatment of familial hypercholesterolaemia. Atherosclerosis (2003) 2.97
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Common promoter variant in cyclooxygenase-2 represses gene expression: evidence of role in acute-phase inflammatory response. Arterioscler Thromb Vasc Biol (2002) 2.84
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Chromosome 9p21.3 coronary heart disease locus genotype and prospective risk of CHD in healthy middle-aged men. Clin Chem (2008) 2.82
Dietary patterns and 15-y risks of major coronary events, diabetes, and mortality. Am J Clin Nutr (2008) 2.80
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
Insight into the nature of the CRP-coronary event association using Mendelian randomization. Int J Epidemiol (2006) 2.70
Alcohol intake and blood pressure: a systematic review implementing a Mendelian randomization approach. PLoS Med (2008) 2.61
Evidence based policy or policy based evidence? BMJ (2004) 2.59
Job strain as a risk factor for leisure-time physical inactivity: an individual-participant meta-analysis of up to 170,000 men and women: the IPD-Work Consortium. Am J Epidemiol (2012) 2.55
Cost effectiveness analysis of different approaches of screening for familial hypercholesterolaemia. BMJ (2002) 2.55
Best-practice interventions to reduce socioeconomic inequalities of coronary heart disease mortality in UK: a prospective occupational cohort study. Lancet (2008) 2.53
Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study. BMJ (2010) 2.53
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet (2012) 2.53
Psychological distress as a risk factor for coronary heart disease in the Whitehall II Study. Int J Epidemiol (2002) 2.53
Coronary calcium measurement improves prediction of cardiovascular events in asymptomatic patients with type 2 diabetes: the PREDICT study. Eur Heart J (2008) 2.52
Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. Am J Respir Crit Care Med (2002) 2.51
Reductions in all-cause, cancer, and coronary mortality in statin-treated patients with heterozygous familial hypercholesterolaemia: a prospective registry study. Eur Heart J (2008) 2.50
Overtime work and incident coronary heart disease: the Whitehall II prospective cohort study. Eur Heart J (2010) 2.46
Endothelial nitric oxide synthase genotype and ischemic heart disease: meta-analysis of 26 studies involving 23028 subjects. Circulation (2004) 2.31
Endothelial function predicts progression of carotid intima-media thickness. Circulation (2009) 2.30
Dietary pattern and depressive symptoms in middle age. Br J Psychiatry (2009) 2.28
Relative contribution of variation within the APOC3/A4/A5 gene cluster in determining plasma triglycerides. Hum Mol Genet (2002) 2.27
Common mental disorder and obesity: insight from four repeat measures over 19 years: prospective Whitehall II cohort study. BMJ (2009) 2.19
Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study. J Am Coll Cardiol (2013) 2.18
Familial hypercholesterolaemia: summary of NICE guidance. BMJ (2008) 2.18
Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height. Am J Hum Genet (2010) 2.15
Critical appraisal of CRP measurement for the prediction of coronary heart disease events: new data and systematic review of 31 prospective cohorts. Int J Epidemiol (2008) 2.14
Prospective effect of job strain on general and central obesity in the Whitehall II Study. Am J Epidemiol (2007) 2.09
Dietary fiber and colorectal cancer risk: a nested case-control study using food diaries. J Natl Cancer Inst (2010) 2.07
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Am J Hum Genet (2009) 2.04
Birth weight, components of height and coronary heart disease: evidence from the Whitehall II study. Int J Epidemiol (2006) 2.04
Organisational justice and change in justice as predictors of employee health: the Whitehall II study. J Epidemiol Community Health (2004) 2.00
Cause-specific mortality in old age in relation to body mass index in middle age and in old age: follow-up of the Whitehall cohort of male civil servants. Int J Epidemiol (2005) 1.98
Cross-sectional versus prospective associations of sleep duration with changes in relative weight and body fat distribution: the Whitehall II Study. Am J Epidemiol (2007) 1.98
Left ventricular wall thickness and the presence of asymmetric hypertrophy in healthy young army recruits: data from the LARGE heart study. Circ Cardiovasc Imaging (2013) 1.98
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
Association of telomere length with type 2 diabetes, oxidative stress and UCP2 gene variation. Atherosclerosis (2009) 1.96
Contribution of modifiable risk factors to social inequalities in type 2 diabetes: prospective Whitehall II cohort study. BMJ (2012) 1.95
Inflammation, insulin resistance, and diabetes--Mendelian randomization using CRP haplotypes points upstream. PLoS Med (2008) 1.95
Using additional information on working hours to predict coronary heart disease: a cohort study. Ann Intern Med (2011) 1.93
Socioeconomic differences in cardiometabolic factors: social causation or health-related selection? Evidence from the Whitehall II Cohort Study, 1991-2004. Am J Epidemiol (2011) 1.90
Social status and health: a comparison of British civil servants in Whitehall-II with European- and African-Americans in CARDIA. Soc Sci Med (2008) 1.89
Low HDL cholesterol is a risk factor for deficit and decline in memory in midlife: the Whitehall II study. Arterioscler Thromb Vasc Biol (2008) 1.88
Angiotensin converting enzyme genotype and strength in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2004) 1.87
Cytokine and cytokine receptor gene polymorphisms and their functionality. Cytokine Growth Factor Rev (2008) 1.85
Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus. Clin Chem (2004) 1.83
ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23. Nat Immunol (2006) 1.83
Unfairness and the social gradient of metabolic syndrome in the Whitehall II Study. J Psychosom Res (2007) 1.80
Peroxisome proliferator--activated receptor alpha gene regulates left ventricular growth in response to exercise and hypertension. Circulation (2002) 1.79
Gender differences in the cross-sectional relationships between sleep duration and markers of inflammation: Whitehall II study. Sleep (2009) 1.77
Does personality explain social inequalities in mortality? The French GAZEL cohort study. Int J Epidemiol (2008) 1.73
Comparative analysis of genome-wide association studies signals for lipids, diabetes, and coronary heart disease: Cardiovascular Biomarker Genetics Collaboration. Eur Heart J (2011) 1.73
Psychological impact of genetic testing for familial hypercholesterolemia within a previously aware population: a randomized controlled trial. Am J Med Genet A (2004) 1.72
Persistent cognitive depressive symptoms are associated with coronary artery calcification. Atherosclerosis (2010) 1.72
In the elderly, interleukin-6 plasma levels and the -174G>C polymorphism are associated with the development of cardiovascular disease. Arterioscler Thromb Vasc Biol (2002) 1.70
Familial hypercholesterolemia and coronary heart disease: a HuGE association review. Am J Epidemiol (2004) 1.70
Sitting behavior and obesity: evidence from the Whitehall II study. Am J Prev Med (2013) 1.69