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1
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Oxidative mechanism of arsenic toxicity and carcinogenesis.
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Mol Cell Biochem
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2004
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2.07
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2
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Normobaric hyperoxia reduces the neurovascular complications associated with delayed tissue plasminogen activator treatment in a rat model of focal cerebral ischemia.
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Stroke
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2009
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1.90
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3
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G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
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Am J Physiol Cell Physiol
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2004
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1.85
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4
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Interstitial pO2 in ischemic penumbra and core are differentially affected following transient focal cerebral ischemia in rats.
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J Cereb Blood Flow Metab
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2004
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1.60
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5
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Enhanced radical scavenging activity by antioxidant-functionalized gold nanoparticles: a novel inspiration for development of new artificial antioxidants.
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Free Radic Biol Med
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2007
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1.59
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6
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Electron paramagnetic resonance-guided normobaric hyperoxia treatment protects the brain by maintaining penumbral oxygenation in a rat model of transient focal cerebral ischemia.
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J Cereb Blood Flow Metab
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2006
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1.54
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7
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Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia.
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J Neurochem
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2009
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1.53
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8
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Arsenite interacts selectively with zinc finger proteins containing C3H1 or C4 motifs.
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J Biol Chem
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2011
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1.45
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9
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Inhibition of poly(ADP-ribose) polymerase-1 by arsenite interferes with repair of oxidative DNA damage.
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J Biol Chem
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2008
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1.44
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10
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Vanadate-induced expression of hypoxia-inducible factor 1 alpha and vascular endothelial growth factor through phosphatidylinositol 3-kinase/Akt pathway and reactive oxygen species.
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J Biol Chem
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2002
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1.41
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11
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Benzo(a)pyrene quinones increase cell proliferation, generate reactive oxygen species, and transactivate the epidermal growth factor receptor in breast epithelial cells.
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Cancer Res
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2003
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1.39
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12
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Arsenite causes DNA damage in keratinocytes via generation of hydroxyl radicals.
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Chem Res Toxicol
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2004
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1.37
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13
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Oxidative stress and apoptosis in metal ion-induced carcinogenesis.
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Free Radic Biol Med
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2004
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1.25
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14
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Normobaric hyperoxia inhibits NADPH oxidase-mediated matrix metalloproteinase-9 induction in cerebral microvessels in experimental stroke.
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J Neurochem
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2008
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1.24
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15
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PUMA overexpression induces reactive oxygen species generation and proteasome-mediated stathmin degradation in colorectal cancer cells.
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Cancer Res
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2005
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1.23
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16
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Inorganic arsenic compounds cause oxidative damage to DNA and protein by inducing ROS and RNS generation in human keratinocytes.
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Mol Cell Biochem
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2005
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1.19
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17
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Use of 3-acetoxymethoxycarbonyl-2,2,5,5-tetramethyl-1-pyrrolidinyloxyl as an EPR oximetry probe: potential for in vivo measurement of tissue oxygenation in mouse brain.
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Magn Reson Med
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2006
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1.18
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18
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Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization.
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J Biol Chem
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2004
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1.15
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19
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Generation of hydrogen peroxide during brief oxygen-glucose deprivation induces preconditioning neuronal protection in primary cultured neurons.
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J Neurosci Res
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2005
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1.14
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20
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Poly(ADP-ribose) contributes to an association between poly(ADP-ribose) polymerase-1 and xeroderma pigmentosum complementation group A in nucleotide excision repair.
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J Biol Chem
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2012
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1.13
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21
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Low concentration of arsenite exacerbates UVR-induced DNA strand breaks by inhibiting PARP-1 activity.
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Toxicol Appl Pharmacol
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2008
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1.11
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22
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Caveolin-1 regulates nitric oxide-mediated matrix metalloproteinases activity and blood-brain barrier permeability in focal cerebral ischemia and reperfusion injury.
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J Neurochem
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2011
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1.10
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23
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Specific inhibition of hypoxia inducible factor 1 exaggerates cell injury induced by in vitro ischemia through deteriorating cellular redox environment.
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J Neurochem
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2009
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1.10
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24
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Direct visualization of mouse brain oxygen distribution by electron paramagnetic resonance imaging: application to focal cerebral ischemia.
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J Cereb Blood Flow Metab
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2009
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1.08
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25
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Glucose up-regulates HIF-1 alpha expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status.
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J Neurochem
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2008
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1.08
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26
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Enhanced ROS production and redox signaling with combined arsenite and UVA exposure: contribution of NADPH oxidase.
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Free Radic Biol Med
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2009
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1.05
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27
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Application of in vivo EPR in brain research: monitoring tissue oxygenation, blood flow, and oxidative stress.
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NMR Biomed
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2004
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1.05
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28
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Dual actions involved in arsenite-induced oxidative DNA damage.
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Chem Res Toxicol
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2008
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29
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Low-dose synergistic immunosuppression of T-dependent antibody responses by polycyclic aromatic hydrocarbons and arsenic in C57BL/6J murine spleen cells.
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Toxicol Appl Pharmacol
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2010
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1.02
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30
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Evaluation of spin trapping agents and trapping conditions for detection of cell-generated reactive oxygen species.
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Arch Biochem Biophys
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2005
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1.01
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31
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Cerebral tissue oxygenation and oxidative brain injury during ischemia and reperfusion.
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Front Biosci
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2007
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32
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As(III) inhibits ultraviolet radiation-induced cyclobutane pyrimidine dimer repair via generation of nitric oxide in human keratinocytes.
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Free Radic Biol Med
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2008
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0.99
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33
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Contributions of reactive oxygen species and mitogen-activated protein kinase signaling in arsenite-stimulated hemeoxygenase-1 production.
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Toxicol Appl Pharmacol
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2006
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0.99
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34
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Hydroxyl radical formation is greater in striatal core than in penumbra in a rat model of ischemic stroke.
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J Neurosci Res
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2003
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0.99
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35
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Normobaric hyperoxia protects the blood brain barrier through inhibiting Nox2 containing NADPH oxidase in ischemic stroke.
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Med Gas Res
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2011
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0.98
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36
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Reduction of arsenite-enhanced ultraviolet radiation-induced DNA damage by supplemental zinc.
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Toxicol Appl Pharmacol
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2013
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Acetoxymethoxycarbonyl nitroxides as electron paramagnetic resonance proimaging agents to measure O2 levels in mouse brain: a pharmacokinetic and pharmacodynamic study.
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J Pharmacol Exp Ther
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2006
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Poly(ADP-ribose) polymerase-1 inhibition by arsenite promotes the survival of cells with unrepaired DNA lesions induced by UV exposure.
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Toxicol Sci
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2012
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Differential binding of monomethylarsonous acid compared to arsenite and arsenic trioxide with zinc finger peptides and proteins.
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Chem Res Toxicol
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2014
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AUF-1 mediates inhibition by nitric oxide of lipopolysaccharide-induced matrix metalloproteinase-9 expression in cultured astrocytes.
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J Neurosci Res
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2006
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41
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Immunotoxicity and biodistribution analysis of arsenic trioxide in C57Bl/6 mice following a 2-week inhalation exposure.
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Toxicol Appl Pharmacol
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2009
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42
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Nitric oxide down-regulates caveolin-1 expression in rat brains during focal cerebral ischemia and reperfusion injury.
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J Neurochem
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2006
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0.91
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43
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Effects of glucose concentration on redox status in rat primary cortical neurons under hypoxia.
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Neurosci Lett
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2006
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44
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On the application of 4-hydroxybenzoic acid as a trapping agent to study hydroxyl radical generation during cerebral ischemia and reperfusion.
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Mol Cell Biochem
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2002
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45
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Direct visualization of trapped erythrocytes in rat brain after focal ischemia and reperfusion.
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J Cereb Blood Flow Metab
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2002
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46
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Chelating intracellularly accumulated zinc decreased ischemic brain injury through reducing neuronal apoptotic death.
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Stroke
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Normobaric hyperoxia delays and attenuates early nitric oxide production in focal cerebral ischemic rats.
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Brain Res
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2010
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Differential expression of tissue inhibitor of metalloproteinases-3 in cultured astrocytes and neurons regulates the activation of matrix metalloproteinase-2.
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J Neurosci Res
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2007
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Ebselen induced C6 glioma cell death in oxygen and glucose deprivation.
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Chem Res Toxicol
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Pulsed electron paramagnetic resonance study of domain docking in neuronal nitric oxide synthase: the calmodulin and output state perspective.
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Ischemic neurons activate astrocytes to disrupt endothelial barrier via increasing VEGF expression.
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J Neurochem
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Bcl-2 phosphorylation triggers autophagy switch and reduces mitochondrial damage in limb remote ischemic conditioned rats after ischemic stroke.
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Transl Stroke Res
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Normobaric hyperoxia-based neuroprotective therapies in ischemic stroke.
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Med Gas Res
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Rapid conditioning with oxygen oscillation: neuroprotection by intermittent normobaric hyperoxia after transient focal cerebral ischemia in rats.
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Stroke
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Comparison of two nitroxide labile esters for delivering electron paramagnetic resonance probes into mouse brain.
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AKT-related autophagy contributes to the neuroprotective efficacy of hydroxysafflor yellow A against ischemic stroke in rats.
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Transl Stroke Res
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Interaction of caveolin-1, nitric oxide, and nitric oxide synthases in hypoxic human SK-N-MC neuroblastoma cells.
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J Neurochem
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Mechanism and cellular kinetic studies of the enhancement of antioxidant activity by using surface-functionalized gold nanoparticles.
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Chemistry
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Arsenite Interacts with Dibenzo[def,p]chrysene (DBC) at Low Levels to Suppress Bone Marrow Lymphoid Progenitors in Mice.
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Biol Trace Elem Res
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Inhibition of gp91(phox) contributes towards normobaric hyperoxia afforded neuroprotection in focal cerebral ischemia.
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Brain Res
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Conference Summary and Recent Advances: the 8th Conference on Metal Toxicity and Carcinogenesis.
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Biol Trace Elem Res
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Arseniasis prevalence and mortality in a multiethnic, endemic township in Guizhou, China.
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Int Arch Occup Environ Health
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2008
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Improvement of hematoma absorption and neurological function in patients with acute intracerebral hemorrhage treated with Xueshuantong.
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J Neurol Sci
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Xanthine oxidase activates pro-matrix metalloproteinase-2 in cultured rat vascular smooth muscle cells through non-free radical mechanisms.
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Arch Biochem Biophys
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A novel spin trap for targeting sulfhydryl-containing polypeptides.
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Chem Commun (Camb)
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Autophagy Mediates Astrocyte Death During Zinc-Potentiated Ischemia--Reperfusion Injury.
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Biol Trace Elem Res
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Induction of heme oxygenase 1 by arsenite inhibits cytokine-induced monocyte adhesion to human endothelial cells.
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Toxicol Appl Pharmacol
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Hydroethidine detection of superoxide production during the lithium-pilocarpine model of status epilepticus.
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Epilepsy Res
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The alternative strategy for designing covalent drugs through kinetic effects of pi-stacking on the self-assembled nanoparticles: a model study with antibiotics.
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Nanotechnology
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Highly sensitive free radical detection by nitrone-functionalized gold nanoparticles.
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Nanoscale
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Detection and removal of contaminating hydroxylamines from the spin trap DEPMPO, and re-evaluation of its use to indicate nitrone radical cation formation and S(N)1 reactions.
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Free Radic Biol Med
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Toxicol Appl Pharmacol
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