Published in J Immunol on November 01, 2004
Condensation of the plasma membrane at the site of T lymphocyte activation. J Cell Biol (2005) 2.33
Cytoskeleton-membrane interactions in membrane raft structure. Cell Mol Life Sci (2009) 1.59
Vaccines with enhanced costimulation maintain high avidity memory CTL. J Immunol (2005) 1.12
Caspase-8 and c-FLIPL associate in lipid rafts with NF-kappaB adaptors during T cell activation. J Biol Chem (2007) 1.12
Lipid rafts and regulation of the cytoskeleton during T cell activation. Philos Trans R Soc Lond B Biol Sci (2005) 1.11
Altered dynamics of Kv1.3 channel compartmentalization in the immunological synapse in systemic lupus erythematosus. J Immunol (2007) 1.07
Regulation of PKC-θ function by phosphorylation in T cell receptor signaling. Front Immunol (2012) 1.06
High plasma membrane lipid order imaged at the immunological synapse periphery in live T cells. Mol Membr Biol (2010) 1.04
CD80 and CD86 differentially regulate mechanical interactions of T-cells with antigen-presenting dendritic cells and B-cells. PLoS One (2012) 1.03
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HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling. PLoS One (2007) 1.02
CD44 mobilization in allogeneic dendritic cell-T cell immunological synapse plays a key role in T cell activation. J Leukoc Biol (2008) 1.02
Cross talk between phosphatidylinositol 3-kinase and cyclic AMP (cAMP)-protein kinase a signaling pathways at the level of a protein kinase B/beta-arrestin/cAMP phosphodiesterase 4 complex. Mol Cell Biol (2010) 1.01
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PKC-theta-mediated signal delivery from the TCR/CD28 surface receptors. Front Immunol (2012) 0.97
Induction of higher-avidity human CTLs by vector-mediated enhanced costimulation of antigen-presenting cells. Clin Cancer Res (2005) 0.91
Lowering glycosphingolipid levels in CD4+ T cells attenuates T cell receptor signaling, cytokine production, and differentiation to the Th17 lineage. J Biol Chem (2011) 0.90
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Lck, Membrane Microdomains, and TCR Triggering Machinery: Defining the New Rules of Engagement. Front Immunol (2012) 0.85
Multiple modes of interaction between Lck and CD28. J Immunol (2005) 0.83
Cross talk between CD3 and CD28 is spatially modulated by protein lateral mobility. Mol Cell Biol (2013) 0.83
Segregation of fluorescent membrane lipids into distinct micrometric domains: evidence for phase compartmentation of natural lipids? PLoS One (2011) 0.81
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CD28 sensitizes TCR Ca²⁺ signaling during Ag-independent polarization of plasma membrane rafts. J Immunol (2013) 0.78
The Novel PKCθ from Benchtop to Clinic. J Immunol Res (2015) 0.78
From tango to quadrilla: current views of the immunological synapse. Cell Adh Migr (2007) 0.77
Molecular Mechanisms for cAMP-Mediated Immunoregulation in T cells - Role of Anchored Protein Kinase A Signaling Units. Front Immunol (2016) 0.77
The C-type lectin OCILRP2 costimulates EL4 T cell activation via the DAP12-Raf-MAP kinase pathway. PLoS One (2014) 0.75
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Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci U S A (2017) 0.75
Reversal of the TCR stop signal by CTLA-4. Science (2006) 4.59
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers. J Exp Med (2005) 3.13
T cell costimulation by chemokine receptors. Nat Immunol (2005) 3.00
Acute kidney injury in cirrhosis. Hepatology (2008) 2.43
p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A (2007) 2.31
Circulating and hepatic endocannabinoids and endocannabinoid-related molecules in patients with cirrhosis. Liver Int (2009) 2.27
Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Immunity (2010) 2.22
Orchestration of lymphocyte chemotaxis by mitochondrial dynamics. J Exp Med (2006) 2.10
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells. J Exp Med (2011) 2.06
CD4+CD25+ regulatory T cells suppress mast cell degranulation and allergic responses through OX40-OX40L interaction. Immunity (2008) 1.95
A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest (2010) 1.73
Filamin-A regulates actin-dependent clustering of HIV receptors. Nat Cell Biol (2007) 1.71
Dynamics of subsynaptic vesicles and surface microclusters at the immunological synapse. Sci Signal (2010) 1.69
A novel KIR-associated function: evidence that CpG DNA uptake and shuttling to early endosomes is mediated by KIR3DL2. Blood (2010) 1.67
Anatomically restricted synergistic antiviral activities of innate and adaptive immune cells in the skin. Cell Host Microbe (2013) 1.62
Characterization of a new cancer-associated mutant of p53 with a missense mutation (K351N) in the tetramerization domain. Cell Cycle (2009) 1.57
CD28 interaction with filamin-A controls lipid raft accumulation at the T-cell immunological synapse. Nat Cell Biol (2006) 1.56
The critical role of agrin in the hematopoietic stem cell niche. Blood (2011) 1.54
CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function. Proc Natl Acad Sci U S A (2005) 1.51
The p73 gene is an anti-tumoral target of the RARbeta/gamma-selective retinoid tazarotene. J Invest Dermatol (2004) 1.48
Mast cells counteract regulatory T-cell suppression through interleukin-6 and OX40/OX40L axis toward Th17-cell differentiation. Blood (2009) 1.48
CXCR4-CCR5: a couple modulating T cell functions. Proc Natl Acad Sci U S A (2008) 1.47
ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation. J Exp Med (2004) 1.44
Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas. Proc Natl Acad Sci U S A (2011) 1.42
SKAP-55 regulates integrin adhesion and formation of T cell-APC conjugates. Nat Immunol (2003) 1.41
SLP-76-ADAP adaptor module regulates LFA-1 mediated costimulation and T cell motility. Proc Natl Acad Sci U S A (2009) 1.35
TBX1 is required for inner ear morphogenesis. Hum Mol Genet (2003) 1.30
T cell receptor "inside-out" pathway via signaling module SKAP1-RapL regulates T cell motility and interactions in lymph nodes. Immunity (2010) 1.29
The inner side of T cell lipid rafts. Immunol Lett (2004) 1.26
SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion. Trends Cell Biol (2008) 1.26
Herpes simplex virus disrupts NF-kappaB regulation by blocking its recruitment on the IkappaBalpha promoter and directing the factor on viral genes. J Biol Chem (2006) 1.22
Lipid rafts in lymphocyte activation and migration. Mol Membr Biol (2006) 1.20
Claudin-1 is a p63 target gene with a crucial role in epithelial development. PLoS One (2008) 1.20
An essential role for SKAP-55 in LFA-1 clustering on T cells that cannot be substituted by SKAP-55R. J Exp Med (2005) 1.18
T cells and their partners: The chemokine dating agency. Trends Immunol (2006) 1.18
Pillars article: the CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytes. 1988. J Immunol (2010) 1.14
Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients. J Transl Med (2010) 1.13
Functional defects of SKAP-55-deficient T cells identify a regulatory role for the adaptor in LFA-1 adhesion. Mol Cell Biol (2007) 1.13
Lipid rafts and T cell receptor signaling: a critical re-evaluation. Eur J Immunol (2002) 1.13
Protein tyrosine phosphorylation in T cell signaling. Front Biosci (2002) 1.12
Carcinoembryonic antigen-related cellular adhesion molecule 1 isoforms alternatively inhibit and costimulate human T cell function. J Immunol (2004) 1.11
Membrane rafts play a crucial role in receptor activator of nuclear factor kappaB signaling and osteoclast function. J Biol Chem (2003) 1.08
CD28 co-signaling in the adaptive immune response. Self Nonself (2010) 1.08
Tbx1 regulates population, proliferation and cell fate determination of otic epithelial cells. Dev Biol (2006) 1.07
miR-142-3p prevents macrophage differentiation during cancer-induced myelopoiesis. Immunity (2013) 1.07
Trichostatin A up-regulates p73 and induces Bax-dependent apoptosis in cisplatin-resistant ovarian cancer cells. Mol Cancer Ther (2008) 1.04
CTLA-4 disrupts ZAP70 microcluster formation with reduced T cell/APC dwell times and calcium mobilization. Eur J Immunol (2008) 1.04
CTLA-4 activation of phosphatidylinositol 3-kinase (PI 3-K) and protein kinase B (PKB/AKT) sustains T-cell anergy without cell death. PLoS One (2008) 1.04
DeltaNp63 knockdown mice: A mouse model for AEC syndrome. Am J Med Genet A (2009) 1.03
Modulation of human T-cell functions by reactive nitrogen species. Eur J Immunol (2011) 1.03
Mast cells and Th17 cells contribute to the lymphoma-associated pro-inflammatory microenvironment of angioimmunoblastic T-cell lymphoma. Am J Pathol (2010) 1.02
Vav cooperates with CD28 to induce NF-kappaB activation via a pathway involving Rac-1 and mitogen-activated kinase kinase 1. Eur J Immunol (2002) 1.01
Adhesion shapes T cells for prompt and sustained T-cell receptor signalling. EMBO J (2010) 1.00
The splice variant LOXIN inhibits LOX-1 receptor function through hetero-oligomerization. J Mol Cell Cardiol (2007) 1.00
CTLA-4 trafficking and surface expression. Trends Immunol (2008) 1.00
Murine regulatory T cells differ from conventional T cells in resisting the CTLA-4 reversal of TCR stop-signal. Blood (2012) 1.00
TCR/CD3 mediated stop-signal is decoupled in T-cells from Ctla4 deficient mice. Immunol Lett (2007) 0.99
The pros and cons of chemokines in tumor immunology. Trends Immunol (2012) 0.99
Lymphocyte lipid rafts: structure and function. Curr Opin Immunol (2003) 0.98
Transglutaminase type II is involved in the pathogenesis of endotoxic shock. J Immunol (2008) 0.98
TcR and TcR-CD28 engagement of protein kinase B (PKB/AKT) and glycogen synthase kinase-3 (GSK-3) operates independently of guanine nucleotide exchange factor VAV-1. J Biol Chem (2006) 0.98
Flotillins are involved in the polarization of primitive and mature hematopoietic cells. PLoS One (2009) 0.97
Glioma-associated stem cells: a novel class of tumor-supporting cells able to predict prognosis of human low-grade gliomas. Stem Cells (2014) 0.97
Hypoxia-mediated regulation of macrophage functions in pathophysiology. Int Immunol (2012) 0.96
Cutting Edge: Regulator of G protein signaling-1 selectively regulates gut T cell trafficking and colitic potential. J Immunol (2011) 0.96
CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters. Proc Natl Acad Sci U S A (2004) 0.96
The aryl hydrocarbon receptor modulates acute and late mast cell responses. J Immunol (2012) 0.95
SKAP1 protein PH domain determines RapL membrane localization and Rap1 protein complex formation for T cell receptor (TCR) activation of LFA-1. J Biol Chem (2011) 0.95
Immunopathologies linked to integrin signalling. Semin Immunopathol (2010) 0.94
Regulation and function of SKAP-55 non-canonical motif binding to the SH3c domain of adhesion and degranulation-promoting adaptor protein. J Biol Chem (2006) 0.94
CTL-associated antigen-4 ligation induces rapid T cell polarization that depends on phosphatidylinositol 3-kinase, Vav-1, Cdc42, and myosin light chain kinase. J Immunol (2007) 0.93
Exploring a regulatory role for mast cells: 'MCregs'? Trends Immunol (2010) 0.93
Mast cells enhance proliferation of B lymphocytes and drive their differentiation toward IgA-secreting plasma cells. Blood (2010) 0.92
T cell receptor-interacting molecule acts as a chaperone to modulate surface expression of the CTLA-4 coreceptor. Immunity (2006) 0.92
T-cell signalling and immune system disorders. Expert Rev Mol Med (2005) 0.91
Differential involvement of α4β2, α7 and α9α10 nicotinic acetylcholine receptors in B lymphocyte activation in vitro. Int J Biochem Cell Biol (2010) 0.90
SH2 domain containing leukocyte phosphoprotein of 76-kDa (SLP-76) feedback regulation of ZAP-70 microclustering. Proc Natl Acad Sci U S A (2010) 0.90
IFN-gamma and R-848 dependent activation of human monocyte-derived dendritic cells by Neisseria meningitidis adhesin A. J Immunol (2007) 0.90
Self-antigen presentation by mouse B cells results in regulatory T-cell induction rather than anergy or clonal deletion. Blood (2011) 0.88
Exacerbated experimental autoimmune encephalomyelitis in mast-cell-deficient Kit W-sh/W-sh mice. Lab Invest (2011) 0.87
A p38-dependent pathway regulates DeltaNp63 DNA binding to p53-dependent promoters in UV-induced apoptosis of keratinocytes. Oncogene (2005) 0.86
Phosphatidylinositol 3-kinase p85 adaptor function in T-cells. Co-stimulation and regulation of cytokine transcription independent of associated p110. J Biol Chem (2001) 0.86
Physiological T cell activation starts and propagates in lipid rafts. Immunol Lett (2004) 0.86
Cbl-b mediates TGFβ sensitivity by downregulating inhibitory SMAD7 in primary T cells. J Mol Cell Biol (2013) 0.86
Adaptor SKAP-55 binds p21 activating exchange factor RasGRP1 and negatively regulates the p21-ERK pathway in T-cells. PLoS One (2008) 0.85
Chemokines: coded messages for T-cell missions. Front Biosci (2008) 0.85
Regulatory T cells target chemokine secretion by dendritic cells independently of their capacity to regulate T cell proliferation. J Immunol (2011) 0.84
CD45 ligation expands Tregs by promoting interactions with DCs. J Clin Invest (2014) 0.84
SKAP1 is dispensable for chemokine-induced migration of primary T-cells. Immunol Lett (2009) 0.84
Single-cell dynamics of mast cell-CD4+ CD25+ regulatory T cell interactions. Eur J Immunol (2011) 0.83
Vav-1 and the IKK alpha subunit of I kappa B kinase functionally associate to induce NF-kappa B activation in response to CD28 engagement. J Immunol (2003) 0.83
MAPK p38: alternative and nonstressful in T cells. Nat Immunol (2005) 0.83
Cross-talks in the p53 family: deltaNp63 is an anti-apoptotic target for deltaNp73alpha and p53 gain-of-function mutants. Cell Cycle (2006) 0.83