Published in Am J Pathol on November 01, 2004
Transcriptional profiling of native inner medullary collecting duct cells from rat kidney. Physiol Genomics (2007) 1.71
The role of calcium/calmodulin-activated calcineurin in rapid and slow endocytosis at central synapses. J Neurosci (2010) 1.35
Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism. Dev Biol (2011) 1.27
Calcineurin regulates bone formation by the osteoblast. Proc Natl Acad Sci U S A (2005) 1.16
Calcium/NFAT signalling promotes early nephrogenesis. Dev Biol (2011) 1.10
Calcineurin A-β is required for hypertrophy but not matrix expansion in the diabetic kidney. J Cell Mol Med (2011) 0.90
Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. PLoS Genet (2006) 0.90
TGF-beta upregulation drives tertiary lymphoid organ formation and kidney dysfunction in calcineurin A-alpha heterozygous mice. Am J Physiol Renal Physiol (2009) 0.88
A fluorimetric method for determination of calcineurin activity. Cell Calcium (2007) 0.83
Ablation of calcineurin Aβ reveals hyperlipidemia and signaling cross-talks with phosphodiesterases. J Biol Chem (2012) 0.82
Regulation of cell proliferation and differentiation in the kidney. Front Biosci (Landmark Ed) (2009) 0.82
Calcineurin Aβ regulates NADPH oxidase (Nox) expression and activity via nuclear factor of activated T cells (NFAT) in response to high glucose. J Biol Chem (2013) 0.81
Calcineurin regulation of cytoskeleton organization: a new paradigm to analyse the effects of calcineurin inhibitors on the kidney. J Cell Mol Med (2012) 0.80
Rescue of calcineurin Aα(-/-) mice reveals a novel role for the α isoform in the salivary gland. Am J Pathol (2011) 0.80
Acute calcineurin inhibition with tacrolimus increases phosphorylated UT-A1. Am J Physiol Renal Physiol (2011) 0.78
Nutritional intervention restores muscle but not kidney phenotypes in adult calcineurin Aα null mice. PLoS One (2013) 0.78
A novel interaction between ATOH8 and PPP3CB. Histochem Cell Biol (2015) 0.78
Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol (2014) 0.76
The β isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in αII b β3 integrin signaling. J Thromb Haemost (2014) 0.76
Direct evidence for calcineurin binding to the exon-7 loop of the sodium-bicarbonate cotransporter NBCn1. Int J Biol Sci (2014) 0.75
Divergent effects of calcineurin Aβ on regulatory and conventional T-cell homeostasis. Clin Immunol (2011) 0.75
Stress Response Gene Nupr1 Alleviates Cyclosporin A Nephrotoxicity In Vivo. J Am Soc Nephrol (2016) 0.75
Compensatory renal hypertrophy following uninephrectomy is calcineurin-independent. J Cell Mol Med (2014) 0.75
A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell (1998) 13.56
Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell (1996) 8.77
Calcineurin: form and function. Physiol Rev (2000) 5.26
IGF-1 induces skeletal myocyte hypertrophy through calcineurin in association with GATA-2 and NF-ATc1. Nature (1999) 3.54
Signals transduced by Ca(2+)/calcineurin and NFATc3/c4 pattern the developing vasculature. Cell (2001) 3.37
Impaired cardiac hypertrophic response in Calcineurin Abeta -deficient mice. Proc Natl Acad Sci U S A (2002) 2.56
Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc Natl Acad Sci U S A (2000) 2.47
Skeletal muscle hypertrophy is mediated by a Ca2+-dependent calcineurin signalling pathway. Nature (1999) 2.24
Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. J Clin Invest (2004) 1.95
Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure. Circ Res (2000) 1.82
Altered skeletal muscle phenotypes in calcineurin Aalpha and Abeta gene-targeted mice. Mol Cell Biol (2003) 1.71
Expression of the cyclin kinase inhibitor, p27kip1, in developing and mature human kidney. Kidney Int (1998) 1.66
Defective T cell development and function in calcineurin A beta -deficient mice. Proc Natl Acad Sci U S A (2002) 1.53
A selective role of calcineurin aalpha in synaptic depotentiation in hippocampus. Proc Natl Acad Sci U S A (1999) 1.47
Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation. Am J Physiol Renal Physiol (2002) 1.45
T cell responses in calcineurin A alpha-deficient mice. J Exp Med (1996) 1.44
Involvement of calcineurin in transforming growth factor-beta-mediated regulation of extracellular matrix accumulation. J Biol Chem (2004) 1.32
Tau domains, phosphorylation, and interactions with microtubules. Neurobiol Aging (1995) 1.25
Calcineurin blockade prevents cardiac mitogen-activated protein kinase activation and hypertrophy in renovascular hypertension. J Biol Chem (2000) 1.23
Insulin-like growth factor-I induces renal cell hypertrophy via a calcineurin-dependent mechanism. J Biol Chem (2001) 1.19
Measurement of Calcineurin Phosphatase Activity in Cell Extracts Methods (1996) 1.10
Insulin-like growth factor-I stimulates dephosphorylation of ikappa B through the serine phosphatase calcineurin (protein phosphatase 2B). J Biol Chem (2000) 1.05
Angiotensin II induces myocyte enhancer factor 2- and calcineurin/nuclear factor of activated T cell-dependent transcriptional activation in vascular myocytes. Circ Res (2002) 1.04
Cytoskeletal changes in the brains of mice lacking calcineurin A alpha. J Neurochem (1997) 1.04
Reduction of calcineurin enzymatic activity in Alzheimer's disease: correlation with neuropathologic changes. J Neuropathol Exp Neurol (1996) 1.00
Differential expression of calcineurin A isoforms in the diabetic kidney. J Am Soc Nephrol (2004) 0.97
Cyclosporin A stimulates transcription and procollagen secretion in tubulointerstitial fibroblasts and proximal tubular cells. J Am Soc Nephrol (1990) 0.95
Reduction of calcineurin activity in brain by antisense oligonucleotides leads to persistent phosphorylation of tau protein at Thr181 and Thr231. Mol Pharmacol (1999) 0.91
Cyclosporin exerts a direct fibrogenic effect on human tubulointerstitial cells: roles of insulin-like growth factor I, transforming growth factor beta1, and platelet-derived growth factor. J Pharmacol Exp Ther (1999) 0.90
Cux-1 transgenic mice develop glomerulosclerosis and interstitial fibrosis. Kidney Int (2003) 0.90
Angiotensin II stimulates calcineurin activity in proximal tubule epithelia through AT-1 receptor-mediated tyrosine phosphorylation of the PLC-gamma1 isoform. J Am Soc Nephrol (2002) 0.87
Expression of calcineurin activity and alpha-subunit isoforms in specific segments of the rat nephron. Am J Physiol (1995) 0.85
Cyclosporin A administration during pregnancy induces a permanent nephron deficit in young rabbits. J Am Soc Nephrol (2003) 0.84
Calcineurin Aalpha plays an exclusive role in TCR signaling in mature but not in immature T cells. Eur J Immunol (2002) 0.83
Nox4 NAD(P)H oxidase mediates hypertrophy and fibronectin expression in the diabetic kidney. J Biol Chem (2005) 2.98
Mechanisms of podocyte injury in diabetes: role of cytochrome P450 and NADPH oxidases. Diabetes (2009) 1.87
IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation. Am J Physiol Heart Circ Physiol (2007) 1.82
NAD(P)H oxidase mediates TGF-beta1-induced activation of kidney myofibroblasts. J Am Soc Nephrol (2009) 1.80
Origin of interstitial fibroblasts in an accelerated model of angiotensin II-induced renal fibrosis. Am J Pathol (2005) 1.64
AMP-activated protein kinase (AMPK) negatively regulates Nox4-dependent activation of p53 and epithelial cell apoptosis in diabetes. J Biol Chem (2010) 1.60
Calcineurin is activated in diabetes and is required for glomerular hypertrophy and ECM accumulation. Am J Physiol Renal Physiol (2002) 1.45
Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin. Am J Pathol (2007) 1.41
Kidney involvement in a nongenetic rat model of type 2 diabetes. Kidney Int (2005) 1.31
Inhibition of autoregulated TGFbeta signaling simultaneously enhances proliferation and differentiation of kidney epithelium and promotes repair following renal ischemia. Am J Pathol (2009) 1.27
Docosahexaenoic acid-enriched fish oil attenuates kidney disease and prolongs median and maximal life span of autoimmune lupus-prone mice. J Immunol (2010) 1.22
ZO-1 expression and phosphorylation in diabetic nephropathy. Diabetes (2006) 1.14
Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury. Diabetes (2013) 1.08
Loss of calcineurin Aalpha results in altered trafficking of AQP2 and in nephrogenic diabetes insipidus. J Cell Sci (2006) 1.04
Morphological insights into the origin of glomerular endothelial and mesangial cells and their precursors. J Histochem Cytochem (2003) 0.98
Translational regulation of vascular endothelial growth factor expression in renal epithelial cells by angiotensin II. Am J Physiol Renal Physiol (2004) 0.97
Differential expression of calcineurin A isoforms in the diabetic kidney. J Am Soc Nephrol (2004) 0.97
PRAS40 acts as a nodal regulator of high glucose-induced TORC1 activation in glomerular mesangial cell hypertrophy. J Cell Physiol (2010) 0.95
ADAM17 mediates Nox4 expression and NADPH oxidase activity in the kidney cortex of OVE26 mice. Am J Physiol Renal Physiol (2013) 0.95
Resveratrol ameliorates high glucose-induced protein synthesis in glomerular epithelial cells. Cell Signal (2009) 0.94
Toxicity of a second autologous peripheral blood stem cell transplant in patients with relapsed or recurrent multiple myeloma. Leuk Lymphoma (2009) 0.94
Candida krusei sepsis secondary to oral colonization in a hemopoietic stem cell transplant recipient. Med Mycol (2007) 0.92
Nephrogenic systemic fibrosis: evidence for oxidative stress and bone marrow-derived fibrocytes in skin, liver, and heart lesions using a 5/6 nephrectomy rodent model. Am J Pathol (2012) 0.86
Fibronectin induces ureteric bud cells branching and cellular cord and tubule formation. Kidney Int (2004) 0.84
Methodological and logistical considerations to study design and data collection in racial/ethnic minority populations evaluating outcome disparity in hematopoietic cell transplantation. Biol Blood Marrow Transplant (2009) 0.83
Ribosomal biogenesis induction by high glucose requires activation of upstream binding factor in kidney glomerular epithelial cells. Am J Physiol Renal Physiol (2010) 0.82
Molecular events in matrix protein metabolism in the aging kidney. Aging Cell (2012) 0.82
Role of β-adrenergic receptors in regulation of hepatic fat accumulation during aging. J Endocrinol (2012) 0.81
Acute hyperglycemia rapidly stimulates VEGF mRNA translation in the kidney. Role of angiotensin type 2 receptor (AT2). Cell Signal (2010) 0.81
The malnutrition-related increase in early visceralization of Leishmania donovani is associated with a reduced number of lymph node phagocytes and altered conduit system flow. PLoS Negl Trop Dis (2013) 0.81
Concentrated fish oil (Lovaza(R)) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW)F1 mice. Exp Biol Med (Maywood) (2013) 0.80
Loss of in vitro resistance in Candida glabrata following discontinuation of fluconazole prophylaxis in a hematopoietic stem cell transplantation patient. Med Mycol (2010) 0.79
Reciprocal induction of simple organogenesis by mouse kidney progenitor cells in three-dimensional co-culture. Am J Pathol (2011) 0.79
Rat mesangial alpha-endosulfine. Kidney Int (2004) 0.78
Microbiology and epidemiology of oral yeast colonization in hemopoietic progenitor cell transplant recipients. Oral Surg Oral Med Oral Pathol Oral Radiol (2013) 0.78
Renal histopathology of a baboon model with type 2 diabetes. Toxicol Pathol (2012) 0.76
Hematopoietic progenitor cell transplantation toxicities in multiple myeloma patients with bisphosphonate-induced osteonecrosis of the jaw: a longitudinal cohort study. Support Care Cancer (2012) 0.75