PubRank

Klaus Scheffzek

Author PubWeight™ 57.04‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell 2003 5.44
2 Splicing regulates NAD metabolite binding to histone macroH2A. Nat Struct Mol Biol 2005 3.40
3 A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol 2009 3.26
4 Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis. Cancer Cell 2009 2.73
5 Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J 2002 1.64
6 The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module. Proc Natl Acad Sci U S A 2008 1.50
7 Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency. Hum Mutat 2012 1.50
8 Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science 2009 1.44
9 U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat Struct Mol Biol 2007 1.38
10 Structural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAV. Nat Struct Mol Biol 2008 1.36
11 A novel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein. EMBO Rep 2006 1.33
12 Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins. Plant Cell 2004 1.33
13 The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. EMBO Rep 2008 1.31
14 Pyrophosphate-producing protein dephosphorylation by HPr kinase/phosphorylase: a relic of early life? Proc Natl Acad Sci U S A 2002 1.23
15 Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization. BMC Biol 2005 1.15
16 Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering. EMBO J 2003 1.13
17 Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions. Mol Endocrinol 2003 1.10
18 Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation. Hum Mutat 2008 1.07
19 Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60. J Biol Chem 2008 1.06
20 Structural basis for the redox control of plant glutamate cysteine ligase. J Biol Chem 2006 1.03
21 The Leishmania tarentolae exosome: purification and structural analysis by electron microscopy. Mol Biochem Parasitol 2008 1.03
22 Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/substrate of the phospho transfer reactions. Proc Natl Acad Sci U S A 2002 0.97
23 Structure of the full-length enzyme I of the phosphoenolpyruvate-dependent sugar phosphotransferase system. J Biol Chem 2006 0.97
24 The sec14 homology module of neurofibromin binds cellular glycerophospholipids: mass spectrometry and structure of a lipid complex. J Mol Biol 2006 0.97
25 Structure and function of the hetero-oligomeric cysteine synthase complex in plants. J Biol Chem 2010 0.95
26 Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP. J Mol Biol 2003 0.93
27 Cyclin box structure of the P-TEFb subunit cyclin T1 derived from a fusion complex with EIAV tat. J Mol Biol 2007 0.93
28 The redox switch of gamma-glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants. Plant J 2008 0.91
29 Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42. J Biol Chem 2003 0.91
30 Inhibition and termination of physiological responses by GTPase activating proteins. Physiol Rev 2012 0.89
31 Enhancing endosomal escape of transduced proteins by photochemical internalisation. PLoS One 2012 0.88
32 Thioredoxin as a fusion tag for carrier-driven crystallization. Protein Sci 2008 0.87
33 Structural insights into the pH-controlled targeting of plant cell-wall invertase by a specific inhibitor protein. Proc Natl Acad Sci U S A 2010 0.87
34 Crystal Structure of the alpha-Actinin Rod: Four Spectrin Repeats Forming a Thight Dimer. Cell Mol Biol Lett 2001 0.86
35 The invertase inhibitor Nt-CIF from tobacco: a highly thermostable four-helix bundle with an unusual N-terminal extension. J Mol Biol 2004 0.86
36 Expression, purification and preliminary crystallographic characterization of a novel segment from the neurofibromatosis type 1 protein. Acta Crystallogr D Biol Crystallogr 2004 0.84
37 Observation of slow dynamic exchange processes in Ras protein crystals by 31P solid state NMR spectroscopy. J Mol Biol 2002 0.83
38 Bacterial expression, purification and preliminary X-ray crystallographic characterization of the invertase inhibitor Nt-CIF from tobacco. Acta Crystallogr D Biol Crystallogr 2003 0.81
39 Structural and biochemical consequences of NF1 associated nontruncating mutations in the Sec14-PH module of neurofibromin. Hum Mutat 2011 0.79
40 Evolutionary relationship between the bacterial HPr kinase and the ubiquitous PEP-carboxykinase: expanding the P-loop nucleotidyl transferase superfamily. FEBS Lett 2002 0.79
41 Functional MHC class II is upregulated in neurofibromin-deficient Schwann cells. J Invest Dermatol 2013 0.78
42 Solubility survey of fragments of the neurofibromatosis type 1 protein neurofibromin. Protein Expr Purif 2008 0.78
43 Allosterically gated enzyme dynamics in the cysteine synthase complex regulate cysteine biosynthesis in Arabidopsis thaliana. Structure 2012 0.78
44 Multiple crystal forms of the cell-wall invertase inhibitor from tobacco support high conformational rigidity over a broad pH range. Acta Crystallogr D Biol Crystallogr 2006 0.77
45 Activity of the Enterococcus faecalis EIIA(gnt) PTS component and its strong interaction with EIIB(gnt). Biochem Biophys Res Commun 2009 0.76
46 Structure of the Enterococcus faecalis EIIA(gnt) PTS component. Biochem Biophys Res Commun 2009 0.76
47 How Ran is regulated. Results Probl Cell Differ 2002 0.75