Published in J Mol Biol on November 18, 2006
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The Sec14 superfamily and mechanisms for crosstalk between lipid metabolism and lipid signaling. Trends Biochem Sci (2009) 1.46
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Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms. Acta Neuropathol (2011) 1.04
The RasGAP proteins Ira2 and neurofibromin are negatively regulated by Gpb1 in yeast and ETEA in humans. Mol Cell Biol (2010) 1.03
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Phospholipid transfer protein Sec14 is required for trafficking from endosomes and regulates distinct trans-Golgi export pathways. J Biol Chem (2009) 0.97
Genetically engineered mouse models shed new light on the pathogenesis of neurofibromatosis type I-related neoplasms of the peripheral nervous system. Brain Res Bull (2011) 0.88
Alternative splicing of the neurofibromatosis type I pre-mRNA. Biosci Rep (2012) 0.82
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From neurodevelopment to neurodegeneration: the interaction of neurofibromin and valosin-containing protein/p97 in regulation of dendritic spine formation. J Biomed Sci (2012) 0.80
Breakpoint characterization of a novel NF1 multiexonic deletion: a case showing expression of the mutated allele. Neurogenetics (2008) 0.79
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Sec14 like PITPs couple lipid metabolism with phosphoinositide synthesis to regulate Golgi functionality. Subcell Biochem (2012) 0.78
Neuregulin-1 overexpression and Trp53 haploinsufficiency cooperatively promote de novo malignant peripheral nerve sheath tumor pathogenesis. Acta Neuropathol (2014) 0.77
Partial Blindness to Submicron Topography in NF1 Haploinsufficient Cultured Fibroblasts Indicates a New Function of Neurofibromin in Regulation of Mechanosensoric. Mol Syndromol (2012) 0.75
Elucidation of the anti-autophagy mechanism of the Legionella effector RavZ using semisynthetic LC3 proteins. Elife (2017) 0.75
Neurofibromin homologs Ira1 and Ira2 affect glycerophosphoinositol production and transport in Saccharomyces cerevisiae. Eukaryot Cell (2009) 0.75
Structural basis for the autoinhibition of c-Abl tyrosine kinase. Cell (2003) 5.44
Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB. Nature (2010) 5.23
Nuclear pore components are involved in the transcriptional regulation of dosage compensation in Drosophila. Mol Cell (2006) 3.98
APPL proteins link Rab5 to nuclear signal transduction via an endosomal compartment. Cell (2004) 3.95
Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome. Science (2002) 3.59
The conserved Nup107-160 complex is critical for nuclear pore complex assembly. Cell (2003) 3.58
A Polycomb group protein complex with sequence-specific DNA-binding and selective methyl-lysine-binding activities. Genes Dev (2006) 3.49
Reverse genetics in the mosquito Anopheles gambiae: targeted disruption of the Defensin gene. EMBO Rep (2002) 3.43
Splicing regulates NAD metabolite binding to histone macroH2A. Nat Struct Mol Biol (2005) 3.40
A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation. Nat Struct Mol Biol (2009) 3.26
Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method. Proc Natl Acad Sci U S A (2002) 3.14
An enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway. J Cell Biol (2005) 2.97
HURP is part of a Ran-dependent complex involved in spindle formation. Curr Biol (2006) 2.74
Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis. Cancer Cell (2009) 2.73
Genome-wide analysis of mRNAs regulated by the THO complex in Drosophila melanogaster. Nat Struct Mol Biol (2004) 2.70
The Rab5 effector Rabankyrin-5 regulates and coordinates different endocytic mechanisms. PLoS Biol (2004) 2.59
Pcl-PRC2 is needed to generate high levels of H3-K27 trimethylation at Polycomb target genes. EMBO J (2007) 2.49
Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein. EMBO J (2002) 2.39
RBM5/Luca-15/H37 regulates Fas alternative splice site pairing after exon definition. Mol Cell (2008) 2.39
A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing. EMBO J (2004) 2.20
Studies of a ring-cleaving dioxygenase illuminate the role of cholesterol metabolism in the pathogenesis of Mycobacterium tuberculosis. PLoS Pathog (2009) 2.16
RanGTP mediates nuclear pore complex assembly. Nature (2003) 2.08
Complexes between the nonsense-mediated mRNA decay pathway factor human upf1 (up-frameshift protein 1) and essential nonsense-mediated mRNA decay factors in HeLa cells. Biochem J (2003) 1.74
An efficient protein complex purification method for functional proteomics in higher eukaryotes. Nat Biotechnol (2002) 1.71
The nonspecific lethal complex is a transcriptional regulator in Drosophila. Mol Cell (2010) 1.68
Structural basis for the reversible activation of a Rho protein by the bacterial toxin SopE. EMBO J (2002) 1.64
Characterization of 3-ketosteroid 9{alpha}-hydroxylase, a Rieske oxygenase in the cholesterol degradation pathway of Mycobacterium tuberculosis. J Biol Chem (2009) 1.64
The FACT Spt16 "peptidase" domain is a histone H3-H4 binding module. Proc Natl Acad Sci U S A (2008) 1.50
Mutations in SYNGAP1 cause intellectual disability, autism, and a specific form of epilepsy by inducing haploinsufficiency. Hum Mutat (2012) 1.50
Legionella pneumophila glucosyltransferase inhibits host elongation factor 1A. Proc Natl Acad Sci U S A (2006) 1.48
Catalytic core of a membrane-associated eukaryotic polyphosphate polymerase. Science (2009) 1.44
Nup155 regulates nuclear envelope and nuclear pore complex formation in nematodes and vertebrates. EMBO J (2005) 1.39
MOF-regulated acetylation of MSL-3 in the Drosophila dosage compensation complex. Mol Cell (2003) 1.39
U2AF-homology motif interactions are required for alternative splicing regulation by SPF45. Nat Struct Mol Biol (2007) 1.38
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules. Mol Biol Cell (2006) 1.37
Structural insights into the cyclin T1-Tat-TAR RNA transcription activation complex from EIAV. Nat Struct Mol Biol (2008) 1.36
A novel bipartite phospholipid-binding module in the neurofibromatosis type 1 protein. EMBO Rep (2006) 1.33
Structural insights into the target specificity of plant invertase and pectin methylesterase inhibitory proteins. Plant Cell (2004) 1.33
The C2 domain of SynGAP is essential for stimulation of the Rap GTPase reaction. EMBO Rep (2008) 1.31
The DEXD/H-box RNA helicase RHII/Gu is a co-factor for c-Jun-activated transcription. EMBO J (2002) 1.30
Identification of 40LoVe, a Xenopus hnRNP D family protein involved in localizing a TGF-beta-related mRNA during oogenesis. Dev Cell (2005) 1.30
Splicing factors stimulate polyadenylation via USEs at non-canonical 3' end formation signals. EMBO J (2007) 1.27
Structure of human NMN adenylyltransferase. A key nuclear enzyme for NAD homeostasis. J Biol Chem (2001) 1.23
Pyrophosphate-producing protein dephosphorylation by HPr kinase/phosphorylase: a relic of early life? Proc Natl Acad Sci U S A (2002) 1.23
Hsp90 enables Ctf13p/Skp1p to nucleate the budding yeast kinetochore. Proc Natl Acad Sci U S A (2002) 1.23
Role of Met-542 as a guide for the conformational changes of Phe-601 that occur during the reaction of β-galactosidase (Escherichia coli). Biochem Cell Biol (2010) 1.23
Sex-lethal imparts a sex-specific function to UNR by recruiting it to the msl-2 mRNA 3' UTR: translational repression for dosage compensation. Genes Dev (2006) 1.22
Human Lsg1 defines a family of essential GTPases that correlates with the evolution of compartmentalization. BMC Biol (2005) 1.15
Preprocessing of tandem mass spectrometric data to support automatic protein identification. Proteomics (2003) 1.14
Importin alpha associates with membranes and participates in nuclear envelope assembly in vitro. EMBO J (2004) 1.14
Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering. EMBO J (2003) 1.13
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol (2008) 1.13
Combination of peptide OFFGEL fractionation and label-free quantitation facilitated proteomics profiling of extraocular muscle. Proteomics (2007) 1.12
Biochemical function of female-lethal (2)D/Wilms' tumor suppressor-1-associated proteins in alternative pre-mRNA splicing. J Biol Chem (2002) 1.11
"De novo" sequencing of peptides recovered from in-gel digested proteins by nanoelectrospray tandem mass spectrometry. Mol Biotechnol (2002) 1.10
Crystal structure and nuclear magnetic resonance analyses of the SAND domain from glucocorticoid modulatory element binding protein-1 reveals deoxyribonucleic acid and zinc binding regions. Mol Endocrinol (2003) 1.10
DMSO enhances electrospray response, boosting sensitivity of proteomic experiments. Nat Methods (2013) 1.09
Mutation analysis in Costello syndrome: functional and structural characterization of the HRAS p.Lys117Arg mutation. Hum Mutat (2008) 1.07
Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60. J Biol Chem (2008) 1.06
A flavin-dependent monooxygenase from Mycobacterium tuberculosis involved in cholesterol catabolism. J Biol Chem (2010) 1.04
IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation. Blood (2006) 1.03
The Leishmania tarentolae exosome: purification and structural analysis by electron microscopy. Mol Biochem Parasitol (2008) 1.03
Structural basis for the redox control of plant glutamate cysteine ligase. J Biol Chem (2006) 1.03
Quantitative proteomics profiling of sarcomere associated proteins in limb and extraocular muscle allotypes. Mol Cell Proteomics (2007) 1.01
Building the stator of the yeast vacuolar-ATPase: specific interaction between subunits E and G. J Biol Chem (2004) 1.01
p38 MAPK controls prothrombin expression by regulated RNA 3' end processing. Mol Cell (2011) 1.01
Costimulation induced phosphorylation of L-plastin facilitates surface transport of the T cell activation molecules CD69 and CD25. Eur J Immunol (2007) 1.00
Nanoelectrospray-based detection and sequencing of substoichiometric amounts of phosphopeptides in complex mixtures. J Mass Spectrom (2003) 0.99
Improving biophysical properties of a bispecific antibody scaffold to aid developability: quality by molecular design. MAbs (2013) 0.98
Structure of the full-length HPr kinase/phosphatase from Staphylococcus xylosus at 1.95 A resolution: Mimicking the product/substrate of the phospho transfer reactions. Proc Natl Acad Sci U S A (2002) 0.97
Structure of the full-length enzyme I of the phosphoenolpyruvate-dependent sugar phosphotransferase system. J Biol Chem (2006) 0.97
Translation initiation by the c-myc mRNA internal ribosome entry sequence and the poly(A) tail. RNA (2008) 0.95
Structure and function of the hetero-oligomeric cysteine synthase complex in plants. J Biol Chem (2010) 0.95
Circular permutation of Bacillus circulans xylanase: a kinetic and structural study. Biochemistry (2010) 0.95
Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP. J Mol Biol (2003) 0.93
Prothymosin alpha associates with the oncoprotein SET and is involved in chromatin decondensation. FEBS Lett (2004) 0.93
Cyclin box structure of the P-TEFb subunit cyclin T1 derived from a fusion complex with EIAV tat. J Mol Biol (2007) 0.93
The redox switch of gamma-glutamylcysteine ligase via a reversible monomer-dimer transition is a mechanism unique to plants. Plant J (2008) 0.91
Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Brain Res (2003) 0.91
Amino acids of the bacterial toxin SopE involved in G nucleotide exchange on Cdc42. J Biol Chem (2003) 0.91
The human T locus and spina bifida risk. Hum Genet (2004) 0.90
Noise filtering techniques for electrospray quadrupole time of flight mass spectra. J Am Soc Mass Spectrom (2003) 0.90
Inhibition and termination of physiological responses by GTPase activating proteins. Physiol Rev (2012) 0.89
A compartmentalized phosphorylation/dephosphorylation system that regulates U snRNA export from the nucleus. Mol Cell Biol (2007) 0.89
Enhancing endosomal escape of transduced proteins by photochemical internalisation. PLoS One (2012) 0.88
Structural insights into the pH-controlled targeting of plant cell-wall invertase by a specific inhibitor protein. Proc Natl Acad Sci U S A (2010) 0.87
Thioredoxin as a fusion tag for carrier-driven crystallization. Protein Sci (2008) 0.87
Crystal Structure of the alpha-Actinin Rod: Four Spectrin Repeats Forming a Thight Dimer. Cell Mol Biol Lett (2001) 0.86
The invertase inhibitor Nt-CIF from tobacco: a highly thermostable four-helix bundle with an unusual N-terminal extension. J Mol Biol (2004) 0.86
Structural basis for targeting the chromatin repressor Sfmbt to Polycomb response elements. Genes Dev (2013) 0.85
Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma. J Biol Chem (2007) 0.85
Expression, purification and preliminary crystallographic characterization of a novel segment from the neurofibromatosis type 1 protein. Acta Crystallogr D Biol Crystallogr (2004) 0.84
Structural diversity of the active N-terminal kinase domain of p90 ribosomal S6 kinase 2. PLoS One (2009) 0.84
A general precursor ion-like scanning mode on quadrupole-TOF instruments compatible with chromatographic separation. Proteomics (2006) 0.83