ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 15546919)

Published in J Cell Sci on November 16, 2004

Authors

Stacey T T I1, Zhongzhen Nie, Ashley Stewart, Meri Najdovska, Nathan E Hall, Hong He, Paul A Randazzo, Peter Lock

Author Affiliations

1: Department of Surgery, University of Melbourne, Level 5 Clinical Sciences Building, Royal Melbourne Hospital, VIC 3050, Australia.

Articles citing this

Predicting protein post-translational modifications using meta-analysis of proteome scale data sets. Mol Cell Proteomics (2008) 1.76

Src and FAK kinases cooperate to phosphorylate paxillin kinase linker, stimulate its focal adhesion localization, and regulate cell spreading and protrusiveness. Mol Biol Cell (2005) 1.69

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation. J Cell Sci (2009) 1.51

The Diasporin Pathway: a tumor progression-related transcriptional network that predicts breast cancer survival. Clin Exp Metastasis (2008) 1.36

Receptors of anthrax toxin and cell entry. Mol Aspects Med (2009) 1.18

Quantitative time-resolved phosphoproteomic analysis of mast cell signaling. J Immunol (2007) 1.16

ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion. J Biol Chem (2008) 1.12

Targeting the anthrax receptors, TEM-8 and CMG-2, for anti-angiogenic therapy. Front Biosci (Landmark Ed) (2011) 1.10

ARAP1 regulates endocytosis of EGFR. Traffic (2008) 1.10

PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1. J Biol Chem (2010) 0.97

A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes. J Biol Chem (2009) 0.92

SSeCKS/Gravin/AKAP12 attenuates expression of proliferative and angiogenic genes during suppression of v-Src-induced oncogenesis. BMC Cancer (2006) 0.88

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS. Proteome Sci (2009) 0.88

A mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection. PLoS Comput Biol (2012) 0.86

ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking. Biol Cell (2011) 0.85

Rho GAPs and GEFs: controling switches in endothelial cell adhesion. Cell Adh Migr (2014) 0.82

The Sam domain of the lipid phosphatase Ship2 adopts a common model to interact with Arap3-Sam and EphA2-Sam. BMC Struct Biol (2009) 0.82

ARAP3 functions in hematopoietic stem cells. PLoS One (2014) 0.79

Nutrient restriction of glucose or serum results in similar proteomic expression changes in 3D colon cancer cell cultures. Nutr Res (2016) 0.78

Heterotypic Sam-Sam association between Odin-Sam1 and Arap3-Sam: binding affinity and structural insights. Chembiochem (2012) 0.76

Arf proteins in cancer cell migration. Small GTPases (2016) 0.75

Articles by these authors

Effect of a treatment strategy of tight control for rheumatoid arthritis (the TICORA study): a single-blind randomised controlled trial. Lancet (2004) 7.90

Functional impairment of CD8(+) T cells by regulatory T cells during persistent retroviral infection. Immunity (2004) 3.10

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice. J Clin Invest (2008) 2.95

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation. Cancer Cell (2012) 2.66

Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4. EMBO J (2009) 2.34

Prevalence of peg-shaped maxillary permanent lateral incisors: A meta-analysis. Am J Orthod Dentofacial Orthop (2013) 2.14

An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells. Blood (2011) 2.10

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling. Nat Med (2005) 2.06

Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts. Cancer Res (2002) 1.96

Arf and its many interactors. Curr Opin Cell Biol (2003) 1.94

ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat. J Cell Biol (2002) 1.82

Invadopodia: at the cutting edge of tumour invasion. J Clin Neurosci (2008) 1.77

Arf GAPs and their interacting proteins. Traffic (2007) 1.76

Epigenetic downregulation of the DNA repair gene MED1/MBD4 in colorectal and ovarian cancer. Cancer Biol Ther (2009) 1.72

Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Dev Biol (2002) 1.70

IL-6 regulates neutrophil trafficking during acute inflammation via STAT3. J Immunol (2008) 1.69

Arf GAPs and membrane traffic. J Cell Sci (2006) 1.67

A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand. J Biol Chem (2008) 1.66

ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell (2002) 1.53

Nck adaptor proteins link Tks5 to invadopodia actin regulation and ECM degradation. J Cell Sci (2009) 1.51

Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras. Mol Cell Biol (2010) 1.50

Src-dependent phosphorylation of ASAP1 regulates podosomes. Mol Cell Biol (2007) 1.48

A role for BARS at the fission step of COPI vesicle formation from Golgi membrane. EMBO J (2005) 1.48

Identification of orthosteric and allosteric site mutations in M2 muscarinic acetylcholine receptors that contribute to ligand-selective signaling bias. J Biol Chem (2010) 1.46

CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor. J Biol Chem (2004) 1.45

Consensus nomenclature for the human ArfGAP domain-containing proteins. J Cell Biol (2008) 1.42

Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome. Mol Biol Cell (2008) 1.40

A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor. Curr Biol (2006) 1.40

Norwalk virus does not replicate in human macrophages or dendritic cells derived from the peripheral blood of susceptible humans. Virology (2010) 1.40

Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A (2007) 1.39

Ephrin-A5 induces rounding, blebbing and de-adhesion of EphA3-expressing 293T and melanoma cells by CrkII and Rho-mediated signalling. J Cell Sci (2002) 1.38

AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton. J Biol Chem (2002) 1.37

CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Mol Biol Cell (2004) 1.34

Uterine natural killer cells: insights into their cellular and molecular biology from mouse modelling. Reproduction (2003) 1.33

Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy. J Immunol (2003) 1.31

Regulation of membrane trafficking and organ separation by the NEVERSHED ARF-GAP protein. Development (2009) 1.30

P21-activated kinase 1 stimulates colon cancer cell growth and migration/invasion via ERK- and AKT-dependent pathways. Biochim Biophys Acta (2010) 1.25

A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin. J Cell Biol (2006) 1.24

Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor. J Biol Chem (2004) 1.23

Immortalization of human uterine leiomyoma and myometrial cell lines after induction of telomerase activity: molecular and phenotypic characteristics. Lab Invest (2002) 1.22

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis. Blood (2005) 1.22

The mitogen-induced increase in T cell size involves PKC and NFAT activation of Rel/NF-kappaB-dependent c-myc expression. Immunity (2004) 1.22

Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1. Dev Cell (2003) 1.22

ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. J Cell Sci (2006) 1.21

ENaC proteolytic regulation by channel-activating protease 2. J Gen Physiol (2008) 1.20

Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell (2002) 1.20

Cell proliferation and apoptosis in human uterine leiomyomas and myometria. Virchows Arch (2002) 1.20

Update on pathways regulating the activation of uterine Natural Killer cells, their interactions with decidual spiral arteries and homing of their precursors to the uterus. J Reprod Immunol (2003) 1.19

Modifications to the C-terminus of Arf1 alter cell functions and protein interactions. Traffic (2010) 1.17

Identification of betaArrestin2 as a corepressor of androgen receptor signaling in prostate cancer. Proc Natl Acad Sci U S A (2009) 1.17

Genetic deletion of placenta growth factor in mice alters uterine NK cells. J Immunol (2007) 1.16

Preparation of myristoylated Arf1 and Arf6. Methods Enzymol (2005) 1.15

The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3. J Cell Sci (2005) 1.14

Kinetic analysis of GTP hydrolysis catalysed by the Arf1-GTP-ASAP1 complex. Biochem J (2007) 1.14

Characterization of an antagonist interleukin-6 dimer by stable isotope labeling, cross-linking, and mass spectrometry. J Biol Chem (2002) 1.14

Inorganic selenium retards progression of experimental hormone refractory prostate cancer. J Urol (2004) 1.13

The K252a derivatives, inhibitors for the PAK/MLK kinase family selectively block the growth of RAS transformants. Cancer J (2002) 1.12

ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion. J Biol Chem (2008) 1.12

Nucleotide exchange factors: Kinetic analyses and the rationale for studying kinetics of GEFs. Cell Logist (2012) 1.10

PAK is essential for RAS-induced upregulation of cyclin D1 during the G1 to S transition. Cell Cycle (2004) 1.10

ARAP1 regulates endocytosis of EGFR. Traffic (2008) 1.10

Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1. J Biol Chem (2008) 1.09

TSLP production by epithelial cells exposed to immunodeficiency virus triggers DC-mediated mucosal infection of CD4+ T cells. Proc Natl Acad Sci U S A (2009) 1.07

Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebrafish. Gastroenterology (2008) 1.07

ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells. Int J Mol Med (2012) 1.07

Differential expression of receptor tyrosine kinases (RTKs) and IGF-I pathway activation in human uterine leiomyomas. Mol Med (2008) 1.07

Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk. J Mol Signal (2006) 1.06

Arf GAPs: gatekeepers of vesicle generation. FEBS Lett (2010) 1.04

Zebrafish gcm2 is required for gill filament budding from pharyngeal ectoderm. Dev Biol (2004) 1.02

Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis. Blood (2006) 1.02

Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains. Cell Signal (2005) 1.00

Highly active catalysts of gold nanoparticles supported on three-dimensionally ordered macroporous LaFeO3 for soot oxidation. Angew Chem Int Ed Engl (2011) 0.99

In situ DRIFTS study of hygroscopic behavior of mineral aerosol. J Environ Sci (China) (2010) 0.99

Cytotoxicity of orthodontic wire corroded in fluoride solution in vitro. Angle Orthod (2007) 0.99

Phosphatidylinositol-4-phosphate 5-kinase and GEP100/Brag2 protein mediate antiangiogenic signaling by semaphorin 3E-plexin-D1 through Arf6 protein. J Biol Chem (2011) 0.98

PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1. J Biol Chem (2010) 0.97

Accurate genotyping from paraffin-embedded normal tissue adjacent to breast cancer. Carcinogenesis (2005) 0.97

Assays and properties of the Arf GAPs AGAP1, ASAP1, and Arf GAP1. Methods Enzymol (2005) 0.96

Derivation and characterization of embryonic stem cells lines derived from transgenic Fischer 344 and Dark Agouti rats. Stem Cells Dev (2011) 0.96

Mutational analysis of the Arf1*GTP/Arf GAP interface reveals an Arf1 mutant that selectively affects the Arf GAP ASAP1. Curr Biol (2005) 0.95

The role of antigen cross-presentation from leukemia blasts on immunity to the leukemia-associated antigen PR1. J Immunother (2012) 0.94

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis. PLoS Genet (2013) 0.94

ARFGAP1 promotes AP-2-dependent endocytosis. Nat Cell Biol (2011) 0.94

Dynamic interaction between Arf GAP and PH domains of ASAP1 in the regulation of GAP activity. Cell Signal (2008) 0.94

Differences between AGAP1, ASAP1 and Arf GAP1 in substrate recognition: interaction with the N-terminus of Arf1. Cell Signal (2004) 0.92

A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes. J Biol Chem (2009) 0.92

Caprin-1 is a novel microRNA-223 target for regulating the proliferation and invasion of human breast cancer cells. Biomed Pharmacother (2013) 0.92

The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17. J Pathol (2011) 0.92

Protective effects of salidroside in the MPTP/MPP(+)-induced model of Parkinson's disease through ROS-NO-related mitochondrion pathway. Mol Neurobiol (2014) 0.92

Distinct requirements for the Sprouty domain for functional activity of Spred proteins. Biochem J (2005) 0.92

Bactericidal activity of a Ce-promoted Ag/AlPO4 catalyst using molecular oxygen in water. Environ Sci Technol (2008) 0.91

Pathways participating in activation of mouse uterine natural killer cells during pregnancy. Biol Reprod (2005) 0.91

Acceptance of 2009 H1N1 influenza vaccine among pregnant women in Delaware. Am J Perinatol (2011) 0.91

Catalytic sterilization of Escherichia coli K 12 on Ag/Al2O3 surface. J Inorg Biochem (2007) 0.91

Estrogen receptor beta mediates the inhibitory effect of estradiol on vascular smooth muscle cell proliferation. Cardiovasc Res (2003) 0.90