Published in Curr Opin Cell Biol on August 01, 2003
Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4. EMBO J (2009) 2.34
Active Arf6 recruits ARNO/cytohesin GEFs to the PM by binding their PH domains. Mol Biol Cell (2007) 2.15
Structure and membrane interaction of myristoylated ARF1. Structure (2009) 2.12
Exit from the Golgi is required for the expansion of the autophagosomal phagophore in yeast Saccharomyces cerevisiae. Mol Biol Cell (2010) 2.10
Dynamics of GBF1, a Brefeldin A-sensitive Arf1 exchange factor at the Golgi. Mol Biol Cell (2004) 2.10
Rhodopsin C terminus, the site of mutations causing retinal disease, regulates trafficking by binding to ADP-ribosylation factor 4 (ARF4). Proc Natl Acad Sci U S A (2005) 1.99
Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins. J Cell Biol (2006) 1.92
Structural basis and mechanism of autoregulation in 3-phosphoinositide-dependent Grp1 family Arf GTPase exchange factors. Mol Cell (2007) 1.76
Hijacking components of the cellular secretory pathway for replication of poliovirus RNA. J Virol (2006) 1.71
A critical role of a cellular membrane traffic protein in poliovirus RNA replication. PLoS Pathog (2008) 1.63
Dynamic regulation of caveolin-1 trafficking in the germ line and embryo of Caenorhabditis elegans. Mol Biol Cell (2006) 1.58
A role for phosphatidic acid in COPI vesicle fission yields insights into Golgi maintenance. Nat Cell Biol (2008) 1.50
Poliovirus proteins induce membrane association of GTPase ADP-ribosylation factor. J Virol (2005) 1.47
An ACAP1-containing clathrin coat complex for endocytic recycling. J Cell Biol (2007) 1.38
Mouse hepatitis coronavirus RNA replication depends on GBF1-mediated ARF1 activation. PLoS Pathog (2008) 1.36
COPI budding within the Golgi stack. Cold Spring Harb Perspect Biol (2011) 1.33
An AP-1/clathrin coat plays a novel and essential role in forming the Weibel-Palade bodies of endothelial cells. J Cell Biol (2005) 1.31
Architecture and biogenesis of plus-strand RNA virus replication factories. World J Virol (2013) 1.30
The TBC (Tre-2/Bub2/Cdc16) domain protein TRE17 regulates plasma membrane-endosomal trafficking through activation of Arf6. Mol Cell Biol (2004) 1.22
What drives cell morphogenesis: a look inside the vertebrate photoreceptor. Dev Dyn (2009) 1.21
The GTPase Arf1p and the ER to Golgi cargo receptor Erv14p cooperate to recruit the golgin Rud3p to the cis-Golgi. J Cell Biol (2004) 1.21
The Gcs1 Arf-GAP mediates Snc1,2 v-SNARE retrieval to the Golgi in yeast. Mol Biol Cell (2006) 1.17
Targeting of Arf-1 to the early Golgi by membrin, an ER-Golgi SNARE. J Cell Biol (2005) 1.16
Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. J Virol (2007) 1.12
Arf6 plays an early role in platelet activation by collagen and convulxin. Blood (2005) 1.12
E3 ubiquitin ligase activity of the trifunctional ARD1 (ADP-ribosylation factor domain protein 1). Proc Natl Acad Sci U S A (2005) 1.11
Lipids and cholesterol as regulators of traffic in the endomembrane system. Annu Rev Biophys (2010) 1.10
ARAP1 regulates endocytosis of EGFR. Traffic (2008) 1.10
Secretory pathways in plant immune responses. Plant Physiol (2008) 1.06
Avl9p, a member of a novel protein superfamily, functions in the late secretory pathway. Mol Biol Cell (2007) 1.05
SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network. Mol Biol Cell (2006) 1.03
Specificity, promiscuity and localization of ARF protein interactions with NCS-1 and phosphatidylinositol-4 kinase-III beta. Traffic (2007) 1.02
Class II ADP-ribosylation factors are required for efficient secretion of dengue viruses. J Biol Chem (2011) 1.02
Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster. J Cell Sci (2010) 1.00
The small GTPase Arf1 modulates Arp2/3-mediated actin polymerization via PICK1 to regulate synaptic plasticity. Neuron (2013) 0.97
Overexpression of Arabidopsis AGD7 causes relocation of Golgi-localized proteins to the endoplasmic reticulum and inhibits protein trafficking in plant cells. Plant Physiol (2007) 0.96
RP2 phenotype and pathogenetic correlations in X-linked retinitis pigmentosa. Arch Ophthalmol (2010) 0.95
Discovery analysis of TCGA data reveals association between germline genotype and survival in ovarian cancer patients. PLoS One (2013) 0.95
Dynamic interaction between Arf GAP and PH domains of ASAP1 in the regulation of GAP activity. Cell Signal (2008) 0.94
Secretion of soluble vascular endothelial growth factor receptor 1 (sVEGFR1/sFlt1) requires Arf1, Arf6, and Rab11 GTPases. PLoS One (2012) 0.92
Selective protection of an ARF1-GTP signaling axis by a bacterial scaffold induces bidirectional trafficking arrest. Cell Rep (2014) 0.89
The leishmania ARL-1 and Golgi traffic. PLoS One (2008) 0.89
Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer. J Biol Chem (2008) 0.88
Interaction of calcium-dependent activator protein for secretion 1 (CAPS1) with the class II ADP-ribosylation factor small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network. J Biol Chem (2010) 0.88
Inhibition of cell migration by PITENINs: the role of ARF6. Oncogene (2011) 0.87
Structural basis for membrane recruitment and allosteric activation of cytohesin family Arf GTPase exchange factors. Proc Natl Acad Sci U S A (2013) 0.87
The capping domain in RalF regulates effector functions. PLoS Pathog (2012) 0.86
Crosstalk of Arf and Rab GTPases en route to cilia. Small GTPases (2013) 0.86
The Arf-GTPase-activating protein Gcs1p is essential for sporulation and regulates the phospholipase D Spo14p. Eukaryot Cell (2006) 0.85
The guanine nucleotide exchange protein for ADP-ribosylation factor 6, ARF-GEP100/BRAG2, regulates phagocytosis of monocytic phagocytes in an ARF6-dependent process. J Biol Chem (2010) 0.84
Arf GAP2 is positively regulated by coatomer and cargo. Cell Signal (2009) 0.84
Abortive autophagy induces endoplasmic reticulum stress and cell death in cancer cells. PLoS One (2012) 0.83
Quantitative proteomic and phosphoproteomic analysis of Trypanosoma cruzi amastigogenesis. Mol Cell Proteomics (2014) 0.81
Behind closed membranes: the secret lives of picornaviruses? PLoS Pathog (2013) 0.80
Asymmetric neuroblast divisions producing apoptotic cells require the cytohesin GRP-1 in Caenorhabditis elegans. Genetics (2014) 0.80
Hyperpolarization-activated cyclic nucleotide gated channels: a potential molecular link between epileptic seizures and Aβ generation in Alzheimer's disease. Mol Neurodegener (2012) 0.79
Mutational analysis of betaCOP (Sec26p) identifies an appendage domain critical for function. BMC Cell Biol (2008) 0.79
Kinetics of interaction between ADP-ribosylation factor-1 (Arf1) and the Sec7 domain of Arno guanine nucleotide exchange factor, modulation by allosteric factors, and the uncompetitive inhibitor brefeldin A. J Biol Chem (2012) 0.77
Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease. J Neurosci (2015) 0.76
Dictyostelium discoideum SecG interprets cAMP-mediated chemotactic signals to influence actin organization. Cytoskeleton (Hoboken) (2013) 0.76
Proteomic Analysis of the Excretory and Secretory Proteins of Haemonchus contortus (HcESP) Binding to Goat PBMCs In Vivo Revealed Stage-Specific Binding Profiles. PLoS One (2016) 0.76
A Method to Generate and Analyze Modified Myristoylated Proteins. Chembiochem (2016) 0.75
Inhibition of WAVE Regulatory Complex Activation by a Bacterial Virulence Effector Counteracts Pathogen Phagocytosis. Cell Rep (2016) 0.75
Expression, purification and preliminary X-ray crystallographic analysis of Arf1-GDP in complex with dimeric p23 peptide. Acta Crystallogr Sect F Struct Biol Cryst Commun (2013) 0.75
Regulators and Effectors of Arf GTPases in Neutrophils. J Immunol Res (2015) 0.75
Ciliary targeting motif VxPx directs assembly of a trafficking module through Arf4. EMBO J (2009) 2.34
Arf GAPs: multifunctional proteins that regulate membrane traffic and actin remodelling. Cell Signal (2004) 1.85
ARFGAP1 promotes the formation of COPI vesicles, suggesting function as a component of the coat. J Cell Biol (2002) 1.82
Arf GAPs and their interacting proteins. Traffic (2007) 1.76
Arf GAPs and membrane traffic. J Cell Sci (2006) 1.67
ARAP1: a point of convergence for Arf and Rho signaling. Mol Cell (2002) 1.53
Semaphorin 3E initiates antiangiogenic signaling through plexin D1 by regulating Arf6 and R-Ras. Mol Cell Biol (2010) 1.50
Src-dependent phosphorylation of ASAP1 regulates podosomes. Mol Cell Biol (2007) 1.48
Consensus nomenclature for the human ArfGAP domain-containing proteins. J Cell Biol (2008) 1.42
Arf GTPase-activating protein ASAP1 interacts with Rab11 effector FIP3 and regulates pericentrosomal localization of transferrin receptor-positive recycling endosome. Mol Biol Cell (2008) 1.40
A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor. Curr Biol (2006) 1.40
Small-molecule synergist of the Wnt/beta-catenin signaling pathway. Proc Natl Acad Sci U S A (2007) 1.39
Cdc42 regulates E-cadherin ubiquitination and degradation through an epidermal growth factor receptor to Src-mediated pathway. J Biol Chem (2007) 1.38
AGAP1, an endosome-associated, phosphoinositide-dependent ADP-ribosylation factor GTPase-activating protein that affects actin cytoskeleton. J Biol Chem (2002) 1.37
CIN85 associates with multiple effectors controlling intracellular trafficking of epidermal growth factor receptors. Mol Biol Cell (2004) 1.34
Regulation of membrane trafficking and organ separation by the NEVERSHED ARF-GAP protein. Development (2009) 1.30
A kinase-deficient TrkC receptor isoform activates Arf6-Rac1 signaling through the scaffold protein tamalin. J Cell Biol (2006) 1.24
Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1. Dev Cell (2003) 1.22
ARAP2 effects on the actin cytoskeleton are dependent on Arf6-specific GTPase-activating-protein activity and binding to RhoA-GTP. J Cell Sci (2006) 1.21
Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell (2002) 1.20
Modifications to the C-terminus of Arf1 alter cell functions and protein interactions. Traffic (2010) 1.17
Preparation of myristoylated Arf1 and Arf6. Methods Enzymol (2005) 1.15
The Arf GAPs AGAP1 and AGAP2 distinguish between the adaptor protein complexes AP-1 and AP-3. J Cell Sci (2005) 1.14
Kinetic analysis of GTP hydrolysis catalysed by the Arf1-GTP-ASAP1 complex. Biochem J (2007) 1.14
ASAP3 is a focal adhesion-associated Arf GAP that functions in cell migration and invasion. J Biol Chem (2008) 1.12
Nucleotide exchange factors: Kinetic analyses and the rationale for studying kinetics of GEFs. Cell Logist (2012) 1.10
ARAP1 regulates endocytosis of EGFR. Traffic (2008) 1.10
Autoinhibition of Arf GTPase-activating protein activity by the BAR domain in ASAP1. J Biol Chem (2008) 1.09
Rac inhibits thrombin-induced Rho activation: evidence of a Pak-dependent GTPase crosstalk. J Mol Signal (2006) 1.06
ARAP3 is transiently tyrosine phosphorylated in cells attaching to fibronectin and inhibits cell spreading in a RhoGAP-dependent manner. J Cell Sci (2004) 1.04
Arf GAPs: gatekeepers of vesicle generation. FEBS Lett (2010) 1.04
Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains. Cell Signal (2005) 1.00
Phosphatidylinositol-4-phosphate 5-kinase and GEP100/Brag2 protein mediate antiangiogenic signaling by semaphorin 3E-plexin-D1 through Arf6 protein. J Biol Chem (2011) 0.98
Rac1 contributes to trastuzumab resistance of breast cancer cells: Rac1 as a potential therapeutic target for the treatment of trastuzumab-resistant breast cancer. Mol Cancer Ther (2009) 0.98
PTK6 inhibits down-regulation of EGF receptor through phosphorylation of ARAP1. J Biol Chem (2010) 0.97
Assays and properties of the Arf GAPs AGAP1, ASAP1, and Arf GAP1. Methods Enzymol (2005) 0.96
Mutational analysis of the Arf1*GTP/Arf GAP interface reveals an Arf1 mutant that selectively affects the Arf GAP ASAP1. Curr Biol (2005) 0.95
Dynamic interaction between Arf GAP and PH domains of ASAP1 in the regulation of GAP activity. Cell Signal (2008) 0.94
A PH domain in the Arf GTPase-activating protein (GAP) ARAP1 binds phosphatidylinositol 3,4,5-trisphosphate and regulates Arf GAP activity independently of recruitment to the plasma membranes. J Biol Chem (2009) 0.92
Differences between AGAP1, ASAP1 and Arf GAP1 in substrate recognition: interaction with the N-terminus of Arf1. Cell Signal (2004) 0.92
Arf1 dissociates from the clathrin adaptor GGA prior to being inactivated by Arf GTPase-activating proteins. J Biol Chem (2002) 0.89
The pleckstrin homology (PH) domain of the Arf exchange factor Brag2 is an allosteric binding site. J Biol Chem (2012) 0.88
Kinetic analysis of Arf GAP1 indicates a regulatory role for coatomer. J Biol Chem (2008) 0.88
In vitro assays of Arf1 interaction with GGA proteins. Methods Enzymol (2005) 0.87
Trastuzumab regulates IGFBP-2 and IGFBP-3 to mediate growth inhibition: implications for the development of predictive biomarkers for trastuzumab resistance. Mol Cancer Ther (2011) 0.86
Contribution of AZAP-Type Arf GAPs to cancer cell migration and invasion. Adv Cancer Res (2008) 0.86
ArfGAP1 function in COPI mediated membrane traffic: currently debated models and comparison to other coat-binding ArfGAPs. Histol Histopathol (2012) 0.85
ARAP1 association with CIN85 affects epidermal growth factor receptor endocytic trafficking. Biol Cell (2011) 0.85
ARAP2 signals through Arf6 and Rac1 to control focal adhesion morphology. J Biol Chem (2013) 0.85
Arf regulates interaction of GGA with mannose-6-phosphate receptor. Traffic (2003) 0.84
Arf GAP2 is positively regulated by coatomer and cargo. Cell Signal (2009) 0.84
The N termini of a-subunit isoforms are involved in signaling between vacuolar H+-ATPase (V-ATPase) and cytohesin-2. J Biol Chem (2013) 0.83
Small GTPase Rho regulates R-cadherin through Dia1/profilin-1. Cell Signal (2012) 0.83
Novel C-terminal motif within Sec7 domain of guanine nucleotide exchange factors regulates ADP-ribosylation factor (ARF) binding and activation. J Biol Chem (2011) 0.83
GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity. J Biol Chem (2012) 0.83
GEFH1 binds ASAP1 and regulates podosome formation. Biochem Biophys Res Commun (2011) 0.83
Trastuzumab alters the expression of genes essential for cardiac function and induces ultrastructural changes of cardiomyocytes in mice. PLoS One (2013) 0.82
Approaches to studying Arf GAPs in cells: in vitro assay with isolated focal adhesions. Curr Protoc Cell Biol (2012) 0.81
Mechanism of E-cadherin lysosomal degradation. Nat Rev Cancer (2009) 0.79
ACAP-A/B are ArfGAP homologs in dictyostelium involved in sporulation but not in chemotaxis. PLoS One (2010) 0.79
Journey to the ends of the Arf. Structure (2009) 0.78
ArfGAP1 promotes COPI vesicle formation by facilitating coatomer polymerization. Cell Logist (2011) 0.77
Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1). J Biol Chem (2016) 0.76
Arf GTPase-activating proteins and their potential role in cell migration and invasion. Cell Adh Migr (2008) 0.75
In vitro and in vivo analysis of neurotrophin-3 activation of Arf6 and Rac-1. Methods Enzymol (2008) 0.75