Published in J Am Soc Nephrol on November 24, 2004
Preservation of intracellular renin expression is insufficient to compensate for genetic loss of secreted renin. Hypertension (2009) 1.68
The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60
Genes that confer the identity of the renin cell. J Am Soc Nephrol (2011) 1.52
CBP and p300 are essential for renin cell identity and morphological integrity of the kidney. Am J Physiol Heart Circ Physiol (2009) 1.47
Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin. Cell Metab (2007) 1.39
Development of the renal arterioles. J Am Soc Nephrol (2011) 1.32
Widespread correlations between dominance and homozygous effects of mutations: implications for theories of dominance. Genetics (2005) 1.28
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Proc Natl Acad Sci U S A (2011) 1.10
Creation and characterization of a renin knockout rat. Hypertension (2011) 1.09
Development of vascular renin expression in the kidney critically depends on the cyclic AMP pathway. Am J Physiol Renal Physiol (2009) 1.08
Role of the renin-angiotensin system in the development of the ureteric bud and renal collecting system. Pediatr Nephrol (2005) 1.06
eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. J Am Soc Nephrol (2012) 1.05
Genetic and developmental basis for urinary tract obstruction. Pediatr Nephrol (2008) 1.01
RBP-J in FOXD1+ renal stromal progenitors is crucial for the proper development and assembly of the kidney vasculature and glomerular mesangial cells. Am J Physiol Renal Physiol (2013) 1.01
Af17 deficiency increases sodium excretion and decreases blood pressure. J Am Soc Nephrol (2011) 1.00
Deletion of von Hippel-Lindau protein converts renin-producing cells into erythropoietin-producing cells. J Am Soc Nephrol (2013) 0.99
Histone deacetylases are critical regulators of the renin-angiotensin system during ureteric bud branching morphogenesis. Pediatr Res (2010) 0.96
Targeted inactivation of EGF receptor inhibits renal collecting duct development and function. J Am Soc Nephrol (2010) 0.94
Clinical and molecular characterization of a family with a dominant renin gene mutation and response to treatment with fludrocortisone. Clin Nephrol (2010) 0.91
Fate and plasticity of renin precursors in development and disease. Pediatr Nephrol (2013) 0.90
A single nucleotide mutation in the mouse renin promoter disrupts blood pressure regulation. J Clin Invest (2008) 0.90
Downregulation of Spry-1, an inhibitor of GDNF/Ret, causes angiotensin II-induced ureteric bud branching. Kidney Int (2008) 0.89
Chronic unilateral ureteral obstruction in the neonatal mouse delays maturation of both kidneys and leads to late formation of atubular glomeruli. Am J Physiol Renal Physiol (2013) 0.88
Angiotensin II AT2 receptor regulates ureteric bud morphogenesis. Am J Physiol Renal Physiol (2009) 0.88
The renin phenotype: roles and regulation in the kidney. Curr Opin Nephrol Hypertens (2010) 0.87
The renin angiotensin system and the metabolic syndrome. Open Hypertens J (2010) 0.86
Renin-angiotensin system-growth factor cross-talk: a novel mechanism for ureteric bud morphogenesis. Pediatr Nephrol (2008) 0.85
Rediscovering ACE: novel insights into the many roles of the angiotensin-converting enzyme. J Mol Med (Berl) (2013) 0.84
Divergent mechanism regulating fluid intake and metabolism by the brain renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol (2011) 0.84
Angiotensin II-induced activation of c-Ret signaling is critical in ureteric bud branching morphogenesis. Mech Dev (2009) 0.84
Angiotensinogen Exerts Effects Independent of Angiotensin II. Arterioscler Thromb Vasc Biol (2015) 0.83
Neuron- or glial-specific ablation of secreted renin does not affect renal renin, baseline arterial pressure, or metabolism. Physiol Genomics (2010) 0.83
Renin-angiotensin system in ureteric bud branching morphogenesis: insights into the mechanisms. Pediatr Nephrol (2011) 0.82
Renal angiotensin-converting enzyme and blood pressure control. Curr Opin Nephrol Hypertens (2014) 0.81
Identification of renin progenitors in the mouse bone marrow that give rise to B-cell leukaemia. Nat Commun (2014) 0.80
AT1a receptor signaling is required for basal and water deprivation-induced urine concentration in AT1a receptor-deficient mice. Am J Physiol Renal Physiol (2012) 0.80
Renin expression in developing zebrafish is associated with angiogenesis and requires the Notch pathway and endothelium. Am J Physiol Renal Physiol (2015) 0.80
A new role for the renin-angiotensin system in the development of the ureteric bud and renal collecting system. Keio J Med (2008) 0.79
(Pro)renin Receptor in Kidney Development and Disease. Int J Nephrol (2011) 0.78
Renin-angiotensin system in ureteric bud branching morphogenesis: implications for kidney disease. Pediatr Nephrol (2013) 0.78
RAS-Mediated Adaptive Mechanisms in Cardiovascular Tissues: Confounding Factors of RAS Blockade Therapy and Alternative Approaches. Cardiorenal Med (2012) 0.78
Angiotensin II regulates growth of the developing papillas ex vivo. Am J Physiol Renal Physiol (2012) 0.78
Vascular versus tubular renin: role in kidney development. Am J Physiol Regul Integr Comp Physiol (2015) 0.77
The ureteric bud epithelium: morphogenesis and roles in metanephric kidney patterning. Mol Reprod Dev (2015) 0.77
Angiotensin inhibition and longevity: a question of hydration. Pflugers Arch (2010) 0.77
Aldo-keto reductase 1b7, a novel marker for renin cells, is regulated by cyclic AMP signaling. Am J Physiol Regul Integr Comp Physiol (2015) 0.76
Dysregulated human renin expression in transgenic mice carrying truncated genomic constructs: evidence supporting the presence of insulators at the renin locus. Am J Physiol Renal Physiol (2008) 0.76
Novel Functions of Renin Precursors in Homeostasis and Disease. Physiology (Bethesda) (2016) 0.75
Vhl deletion in renal epithelia causes HIF-1α-dependent, HIF-2α-independent angiogenesis and constitutive diuresis. Oncotarget (2016) 0.75
Renin-Angiotensin system - considerations for hypertension and kidney. Electrolyte Blood Press (2008) 0.75
Increased Hydration Can Be Associated with Weight Loss. Front Nutr (2016) 0.75
Quantification of intact plasma AGT consisting of oxidized and reduced conformations using a modified ELISA. Am J Physiol Renal Physiol (2016) 0.75
Wnt signaling and renal medulla formation. Pediatr Nephrol (2011) 0.75
Persistent and inducible neogenesis repopulates progenitor renin lineage cells in the kidney. Kidney Int (2017) 0.75
Local renin-angiotensin systems in the genitourinary tract. Naunyn Schmiedebergs Arch Pharmacol (2011) 0.75
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney. Proc Natl Acad Sci U S A (2006) 4.10
Mouse models of diabetic nephropathy. J Am Soc Nephrol (2009) 3.74
Prostacyclin protects against elevated blood pressure and cardiac fibrosis. Cell Metab (2005) 2.82
Distinct roles for the kidney and systemic tissues in blood pressure regulation by the renin-angiotensin system. J Clin Invest (2005) 2.59
Renin cells are precursors for multiple cell types that switch to the renin phenotype when homeostasis is threatened. Dev Cell (2004) 2.52
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science (2002) 2.45
Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction. J Clin Invest (2006) 2.33
Electrospinning of silk fibroin nanofibers and its effect on the adhesion and spreading of normal human keratinocytes and fibroblasts in vitro. Biomaterials (2003) 2.14
Molecular phenotyping for analyzing subtle genetic effects in mice: application to an angiotensinogen gene titration. Proc Natl Acad Sci U S A (2002) 2.08
Hypertension and abnormal fat distribution but not insulin resistance in mice with P465L PPARgamma. J Clin Invest (2004) 1.91
Regulation of renin in mice with Cre recombinase-mediated deletion of G protein Gsalpha in juxtaglomerular cells. Am J Physiol Renal Physiol (2006) 1.86
Ablation of renin-expressing juxtaglomerular cells results in a distinct kidney phenotype. Am J Physiol Regul Integr Comp Physiol (2003) 1.83
Lymphocyte responses exacerbate angiotensin II-dependent hypertension. Am J Physiol Regul Integr Comp Physiol (2010) 1.76
Electrospinning of collagen nanofibers: effects on the behavior of normal human keratinocytes and early-stage wound healing. Biomaterials (2005) 1.76
Stimulation of lymphocyte responses by angiotensin II promotes kidney injury in hypertension. Am J Physiol Renal Physiol (2008) 1.71
Salt-sensitive blood pressure in mice with increased expression of aldosterone synthase. Hypertension (2007) 1.70
A single recurrent mutation in the 5'-UTR of IFITM5 causes osteogenesis imperfecta type V. Am J Hum Genet (2012) 1.70
Disturbed homeostasis in sodium-restricted mice heterozygous and homozygous for aldosterone synthase gene disruption. Hypertension (2006) 1.62
Impaired T cell function in RANTES-deficient mice. Clin Immunol (2002) 1.60
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury. Kidney Int (2012) 1.60
The microRNA-processing enzyme dicer maintains juxtaglomerular cells. J Am Soc Nephrol (2010) 1.60
Analysis of the incidence and clinical effect of the heterotopic ossification in a single-level cervical artificial disc replacement. Spine J (2010) 1.55
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca release channel. J Clin Invest (2007) 1.53
Genes that confer the identity of the renin cell. J Am Soc Nephrol (2011) 1.52
Fibrosis, not cell size, delineates beta-myosin heavy chain reexpression during cardiac hypertrophy and normal aging in vivo. Proc Natl Acad Sci U S A (2006) 1.48
Endothelium-derived nitric oxide supports renin cell recruitment through the nitric oxide-sensitive guanylate cyclase pathway. Hypertension (2013) 1.46
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor. Proc Natl Acad Sci U S A (2004) 1.45
Genes and environment: novel, functional polymorphism in the human cathepsin L (CTSL1) promoter disrupts a xenobiotic response element (XRE) to alter transcription and blood pressure. J Hypertens (2012) 1.41
Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis. J Clin Invest (2009) 1.41
Increased energy expenditure, dietary fat wasting, and resistance to diet-induced obesity in mice lacking renin. Cell Metab (2007) 1.39
Identity of the renin cell is mediated by cAMP and chromatin remodeling: an in vitro model for studying cell recruitment and plasticity. Am J Physiol Heart Circ Physiol (2007) 1.39
Hidden Transection of Follicular Unit Extraction in Donor Site. Dermatol Surg (2016) 1.39
Senescence-associated phenotypes in Akita diabetic mice are enhanced by absence of bradykinin B2 receptors. J Clin Invest (2006) 1.38
Hydrops fetalis, cardiovascular defects, and embryonic lethality in mice lacking the calcitonin receptor-like receptor gene. Mol Cell Biol (2006) 1.35
Development of the renal arterioles. J Am Soc Nephrol (2011) 1.32
Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury. Proc Natl Acad Sci U S A (2007) 1.30
Three-dimensional diffusion tensor microscopy of fixed mouse hearts. Magn Reson Med (2004) 1.28
Lack of both bradykinin B1 and B2 receptors enhances nephropathy, neuropathy, and bone mineral loss in Akita diabetic mice. Proc Natl Acad Sci U S A (2010) 1.26
The ProSeal laryngeal mask airway: a review of the literature. Can J Anaesth (2005) 1.22
Reduced maternal expression of adrenomedullin disrupts fertility, placentation, and fetal growth in mice. J Clin Invest (2006) 1.22
Cardiac hypertrophy and sudden death in mice with a genetically clamped renin transgene. Proc Natl Acad Sci U S A (2004) 1.21
RNA repair restores hemoglobin expression in IVS2-654 thalassemic mice. Proc Natl Acad Sci U S A (2009) 1.21
Serum interleukin-6 and -10 levels in patients with gastric cancer. Gastric Cancer (2009) 1.21
Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol Cell Biol (2007) 1.18
Receptor activity-modifying proteins 2 and 3 have distinct physiological functions from embryogenesis to old age. J Biol Chem (2007) 1.18
Peripherally induced resiniferatoxin analgesia. Pain (2003) 1.17
Posttranscriptional compensation for heterozygous disruption of the kidney-specific NaK2Cl cotransporter gene. J Am Soc Nephrol (2002) 1.16
Transcriptional regulator RBP-J regulates the number and plasticity of renin cells. Physiol Genomics (2011) 1.16
Homeostatic responses in the adrenal cortex to the absence of aldosterone in mice. Endocrinology (2005) 1.16
Embryonic stem cell-like cells established by culture of adult ovarian cells in mice. Fertil Steril (2010) 1.15
A genetically clamped renin transgene for the induction of hypertension. Proc Natl Acad Sci U S A (2002) 1.15
Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin. PLoS One (2009) 1.14
Targeted disruption of hsp70.1 sensitizes to osmotic stress. EMBO Rep (2002) 1.13
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation. Proc Natl Acad Sci U S A (2006) 1.13
Risk factors of sagittal decompensation after long posterior instrumentation and fusion for degenerative lumbar scoliosis. Spine (Phila Pa 1976) (2010) 1.12
Kidney function in mice lacking aldosterone. Am J Physiol Renal Physiol (2005) 1.11
FAST is a BCL-X(L)-associated mitochondrial protein. Biochem Biophys Res Commun (2004) 1.10
A modest decrease in endothelial NOS in mice comparable to that associated with human NOS3 variants exacerbates diabetic nephropathy. Proc Natl Acad Sci U S A (2011) 1.10
Development of vascular renin expression in the kidney critically depends on the cyclic AMP pathway. Am J Physiol Renal Physiol (2009) 1.08
Npr1-regulated gene pathways contributing to cardiac hypertrophy and fibrosis. J Mol Endocrinol (2007) 1.06
Economic evaluation of pneumococcal conjugate vaccination in The Gambia. BMC Infect Dis (2010) 1.06
Limited role for CXC chemokines in the pathogenesis of alpha-naphthylisothiocyanate-induced liver injury. Am J Physiol Gastrointest Liver Physiol (2004) 1.06
Natriuretic peptide receptor A mediates renal sodium excretory responses to blood volume expansion. Am J Physiol Renal Physiol (2003) 1.05
eNOS deficiency acts through endothelin to aggravate sFlt-1-induced pre-eclampsia-like phenotype. J Am Soc Nephrol (2012) 1.05
The kallikrein-kinin system in health and in diseases of the kidney. Kidney Int (2009) 1.04
Heterogeneous myocyte enhancer factor-2 (Mef2) activation in myocytes predicts focal scarring in hypertrophic cardiomyopathy. Proc Natl Acad Sci U S A (2010) 1.03
Selective deletion of Connexin 40 in renin-producing cells impairs renal baroreceptor function and is associated with arterial hypertension. Kidney Int (2010) 1.03
Tissue-specific regulation of ACE/ACE2 and AT1/AT2 receptor gene expression by oestrogen in apolipoprotein E/oestrogen receptor-alpha knock-out mice. Exp Physiol (2008) 1.03
High level expression of functional human IgMs in human PER.C6 cells. MAbs (2009) 1.02
Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice. Horm Behav (2002) 1.02
Novel mechanisms for the control of renin synthesis and release. Curr Hypertens Rep (2010) 1.02
The embryo makes red blood cell progenitors in every tissue simultaneously with blood vessel morphogenesis. Am J Physiol Regul Integr Comp Physiol (2002) 1.01
Altering the expression in mice of genes by modifying their 3' regions. Dev Cell (2004) 1.00
Correction of factor IX deficiency in mice by embryonic stem cells differentiated in vitro. Proc Natl Acad Sci U S A (2005) 1.00