Published in Proc Natl Acad Sci U S A on January 07, 2005
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Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity. Proc Natl Acad Sci U S A (2008) 17.41
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A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design. Nat Biotechnol (2005) 2.51
Local feature frequency profile: a method to measure structural similarity in proteins. Proc Natl Acad Sci U S A (2004) 2.03
Capturing hammerhead ribozyme structures in action by modulating general base catalysis. PLoS Biol (2008) 1.95
A global representation of the protein fold space. Proc Natl Acad Sci U S A (2003) 1.88
Structural basis for the activity of drugs that inhibit phosphodiesterases. Structure (2004) 1.84
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A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases. Mol Cell (2004) 1.64
Global mapping of the protein structure space and application in structure-based inference of protein function. Proc Natl Acad Sci U S A (2005) 1.59
Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states. J Mol Biol (2002) 1.54
Crystal structure of DNA sequence specificity subunit of a type I restriction-modification enzyme and its functional implications. Proc Natl Acad Sci U S A (2005) 1.54
Whole-proteome phylogeny of prokaryotes by feature frequency profiles: An alignment-free method with optimal feature resolution. Proc Natl Acad Sci U S A (2009) 1.44
Global extent of horizontal gene transfer. Proc Natl Acad Sci U S A (2007) 1.43
Whole-genome phylogeny of Escherichia coli/Shigella group by feature frequency profiles (FFPs). Proc Natl Acad Sci U S A (2011) 1.36
Structural analyses of peptide release factor 1 from Thermotoga maritima reveal domain flexibility required for its interaction with the ribosome. J Mol Biol (2004) 1.30
Crystal structure of a nicotinate phosphoribosyltransferase from Thermoplasma acidophilum. J Biol Chem (2005) 1.29
Ethanol production from rice straw using optimized aqueous-ammonia soaking pretreatment and simultaneous saccharification and fermentation processes. Bioresour Technol (2009) 1.28
Crystal structure of conserved hypothetical protein Aq1575 from Aquifex aeolicus. Proc Natl Acad Sci U S A (2002) 1.22
Structural characterization of an iron-sulfur cluster assembly protein IscU in a zinc-bound form. Proteins (2005) 1.18
Improved enzymatic hydrolysis yield of rice straw using electron beam irradiation pretreatment. Bioresour Technol (2008) 1.18
Structural genomics of minimal organisms and protein fold space. J Struct Funct Genomics (2005) 1.16
On-column protein refolding for crystallization. J Struct Funct Genomics (2005) 1.15
Crystal structure of NusA from Thermotoga maritima and functional implication of the N-terminal domain. Biochemistry (2003) 1.15
Evolution of protein structural classes and protein sequence families. Proc Natl Acad Sci U S A (2006) 1.14
Whole-proteome phylogeny of large dsDNA virus families by an alignment-free method. Proc Natl Acad Sci U S A (2009) 1.12
Whole-genome phylogeny of mammals: evolutionary information in genic and nongenic regions. Proc Natl Acad Sci U S A (2009) 1.12
Functional characterization of a bacterial expansin from Bacillus subtilis for enhanced enzymatic hydrolysis of cellulose. Biotechnol Bioeng (2009) 1.12
Exploring the human diseasome: the human disease network. Brief Funct Genomics (2012) 1.11
Crystal structure of YjeQ from Thermotoga maritima contains a circularly permuted GTPase domain. Proc Natl Acad Sci U S A (2004) 1.11
High-throughput T7 LIC vector for introducing C-terminal poly-histidine tags with variable lengths without extra sequences. Protein Expr Purif (2008) 1.11
Global mapping of nucleic acid conformational space: dinucleoside monophosphate conformations and transition pathways among conformational classes. Nucleic Acids Res (2003) 1.09
Genome sequence of Janthinobacterium sp. strain PAMC 25724, isolated from alpine glacier cryoconite. J Bacteriol (2012) 1.08
Structure-based functional inference in structural genomics. J Struct Funct Genomics (2003) 1.08
Structural and molecular genetic insight into a widespread sulfur oxidation pathway. J Mol Biol (2008) 1.05
Structure of the hypothetical protein AQ_1354 from Aquifex aeolicus. Acta Crystallogr D Biol Crystallogr (2003) 1.05
Crystal structure of a phosphatase with a unique substrate binding domain from Thermotoga maritima. Protein Sci (2003) 1.04
Fold prediction of helical proteins using torsion angle dynamics and predicted restraints. Proc Natl Acad Sci U S A (2002) 1.03
Crystal structure of the multidrug efflux transporter AcrB at 3.1A resolution reveals the N-terminal region with conserved amino acids. J Struct Biol (2006) 1.03
Fungal pretreatment of lignocellulose by Phanerochaete chrysosporium to produce ethanol from rice straw. Biotechnol Bioeng (2009) 1.02
Modification of mesenchymal stem cells for cardiac regeneration. Expert Opin Biol Ther (2010) 1.01
Complete genome sequence of a carbon monoxide-utilizing acetogen, Eubacterium limosum KIST612. J Bacteriol (2010) 1.00
Structural and functional characterization of a novel phosphodiesterase from Methanococcus jannaschii. J Biol Chem (2004) 1.00
Chemicals that modulate stem cell differentiation. Proc Natl Acad Sci U S A (2008) 0.99
Depolymerization of alginate into a monomeric sugar acid using Alg17C, an exo-oligoalginate lyase cloned from Saccharophagus degradans 2-40. Appl Microbiol Biotechnol (2012) 0.99
Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif. Proteins (2004) 0.99
Overexpression and molecular characterization of Aga50D from Saccharophagus degradans 2-40: an exo-type beta-agarase producing neoagarobiose. Appl Microbiol Biotechnol (2009) 0.99
SU9516: biochemical analysis of cdk inhibition and crystal structure in complex with cdk2. Biochem Biophys Res Commun (2003) 0.98
Crystal structure of tRNA (m1G37) methyltransferase from Aquifex aeolicus at 2.6 A resolution: a novel methyltransferase fold. Proteins (2003) 0.98
Target selection and deselection at the Berkeley Structural Genomics Center. Proteins (2006) 0.98
Crystal structure of MJ1247 protein from M. jannaschii at 2.0 A resolution infers a molecular function of 3-hexulose-6-phosphate isomerase. Structure (2002) 0.97
Crystal structure of a PhoU protein homologue: a new class of metalloprotein containing multinuclear iron clusters. J Biol Chem (2005) 0.95
Effect of osmotic stress and heat shock in recombinant protein overexpression and crystallization. Protein Expr Purif (2006) 0.95
Crystal structure of the "PhoU-like" phosphate uptake regulator from Aquifex aeolicus. J Bacteriol (2005) 0.95
Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as a fatty acid-binding protein. Proteins (2003) 0.94
Binding characteristics of a bacterial expansin (BsEXLX1) for various types of pretreated lignocellulose. Appl Microbiol Biotechnol (2012) 0.93
Structural basis for CDK6 activation by a virus-encoded cyclin. Nat Struct Biol (2002) 0.93
An expansin-like protein from Hahella chejuensis binds cellulose and enhances cellulase activity. Mol Cells (2010) 0.91
Crystal structures of an NAD kinase from Archaeoglobus fulgidus in complex with ATP, NAD, or NADP. J Mol Biol (2005) 0.91
Crystal structure of flavin binding to FAD synthetase of Thermotoga maritima. Proteins (2005) 0.91
Structure of OsmC from Escherichia coli: a salt-shock-induced protein. Acta Crystallogr D Biol Crystallogr (2004) 0.91
Crystal structure of a key enzyme in the agarolytic pathway, α-neoagarobiose hydrolase from Saccharophagus degradans 2-40. Biochem Biophys Res Commun (2011) 0.91
A method for evaluating the structural quality of protein models by using higher-order phi-psi pairs scoring. Proc Natl Acad Sci U S A (2006) 0.91
Genome sequence of Vibrio sp. strain EJY3, an agarolytic marine bacterium metabolizing 3,6-anhydro-L-galactose as a sole carbon source. J Bacteriol (2012) 0.90
Crystal structure of a stress inducible protein from Mycoplasma pneumoniae at 2.85 A resolution. J Struct Funct Genomics (2003) 0.90
Synergistic proteins for the enhanced enzymatic hydrolysis of cellulose by cellulase. Appl Microbiol Biotechnol (2014) 0.90
Enzymatic production of 3,6-anhydro-L-galactose from agarose and its purification and in vitro skin whitening and anti-inflammatory activities. Appl Microbiol Biotechnol (2012) 0.90
On the mechanism of chaperone activity of the small heat-shock protein of Methanococcus jannaschii. Proc Natl Acad Sci U S A (2003) 0.90
Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii. J Struct Funct Genomics (2002) 0.90
Crystal structure of a flavin-binding protein from Thermotoga maritima. Proteins (2003) 0.90
Structure of O67745_AQUAE, a hypothetical protein from Aquifex aeolicus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.89
Crystal structure of a conserved hypothetical protein from Escherichia coli. J Struct Funct Genomics (2002) 0.89
Structure-based inference of molecular functions of proteins of unknown function from Berkeley Structural Genomics Center. J Struct Funct Genomics (2007) 0.88
Crystal structure of TM1457 from Thermotoga maritima. J Struct Biol (2005) 0.87
Complete genome sequencing of Lactobacillus acidophilus 30SC, isolated from swine intestine. J Bacteriol (2011) 0.86
The complete enzymatic saccharification of agarose and its application to simultaneous saccharification and fermentation of agarose for ethanol production. Bioresour Technol (2011) 0.86
Global metabolite profiling of agarose degradation by Saccharophagus degradans 2-40. N Biotechnol (2010) 0.86
Expression of soluble recombinant proteins in a cell-free system using a 96-well format. J Biochem Biophys Methods (2003) 0.86
Using an Escherichia coli cell-free extract to screen for soluble expression of recombinant proteins. J Struct Funct Genomics (2004) 0.85
Cardiomyocytes from phorbol myristate acetate-activated mesenchymal stem cells restore electromechanical function in infarcted rat hearts. Proc Natl Acad Sci U S A (2010) 0.85
Crystal structure of ScpB from Chlorobium tepidum, a protein involved in chromosome partitioning. Proteins (2006) 0.85
Ethanol production from oil palm trunks treated with aqueous ammonia and cellulase. Bioresour Technol (2011) 0.84
Crystal structure of a phosphotransacetylase from Streptococcus pyogenes. Proteins (2004) 0.84
Genome sequence of a novel member of the genus Psychrobacter isolated from Antarctic soil. J Bacteriol (2012) 0.83
Characteristics of the binding of a bacterial expansin (BsEXLX1) to microcrystalline cellulose. Biotechnol Bioeng (2012) 0.83
Biological pretreatment of rice straw by fermenting with Dichomitus squalens. N Biotechnol (2010) 0.83
Water polygons in high-resolution protein crystal structures. Protein Sci (2009) 0.83
Structural and enzymatic characterization of DR1281: A calcineurin-like phosphoesterase from Deinococcus radiodurans. Proteins (2008) 0.83
Structural proteomics of minimal organisms: conservation of protein fold usage and evolutionary implications. BMC Struct Biol (2006) 0.83
An expansin from the marine bacterium Hahella chejuensis acts synergistically with xylanase and enhances xylan hydrolysis. Bioresour Technol (2013) 0.83
Crystal structure of methenyltetrahydrofolate synthetase from Mycoplasma pneumoniae (GI: 13508087) at 2.2 A resolution. Proteins (2004) 0.82
Structure of a NAD kinase from Thermotoga maritima at 2.3 A resolution. Acta Crystallogr Sect F Struct Biol Cryst Commun (2005) 0.82
Molecular characterization of a novel bacterial aryl acylamidase belonging to the amidase signature enzyme family. Mol Cells (2010) 0.81
Characterization of a recombinant endo-type alginate lyase (Alg7D) from Saccharophagus degradans. Biotechnol Lett (2012) 0.81
Optimal production of a novel endo-acting beta-1,4-xylanase cloned from Saccharophagus degradans 2-40 into Escherichia coli BL21(DE3). N Biotechnol (2009) 0.81
Aqueous ammonia pretreatment of oil palm empty fruit bunches for ethanol production. Bioresour Technol (2011) 0.81