Published in Mol Biol Cell on January 12, 2005
Mitochondria: the next (neurode)generation. Neuron (2011) 3.06
Pink1 forms a multiprotein complex with Miro and Milton, linking Pink1 function to mitochondrial trafficking. Biochemistry (2009) 2.38
Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization. Mol Cell (2008) 2.26
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells. Nat Clin Pract Cardiovasc Med (2007) 2.21
A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol (2011) 2.15
The mitochondrial contact site complex, a determinant of mitochondrial architecture. EMBO J (2011) 1.94
ChChd3, an inner mitochondrial membrane protein, is essential for maintaining crista integrity and mitochondrial function. J Biol Chem (2010) 1.91
Proteomic alterations of distinct mitochondrial subpopulations in the type 1 diabetic heart: contribution of protein import dysfunction. Am J Physiol Regul Integr Comp Physiol (2010) 1.84
(-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J Physiol (2011) 1.72
Formation of cristae and crista junctions in mitochondria depends on antagonism between Fcj1 and Su e/g. J Cell Biol (2009) 1.66
Mitochondrial dysregulation of osteoarthritic human articular chondrocytes analyzed by proteomics: a decrease in mitochondrial superoxide dismutase points to a redox imbalance. Mol Cell Proteomics (2008) 1.66
A Drosophila model of Barth syndrome. Proc Natl Acad Sci U S A (2006) 1.65
Trafficking of heme and porphyrins in metazoa. Chem Rev (2009) 1.48
Transgenic overexpression of mitofilin attenuates diabetes mellitus-associated cardiac and mitochondria dysfunction. J Mol Cell Cardiol (2014) 1.47
One ring to rule them all: trafficking of heme and heme synthesis intermediates in the metazoans. Biochim Biophys Acta (2012) 1.46
MINOS1 is a conserved component of mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell (2011) 1.37
Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem (2009) 1.37
Apoptosis-inducing factor: structure, function, and redox regulation. Antioxid Redox Signal (2011) 1.37
Differential proteomics analysis of synaptic proteins identifies potential cellular targets and protein mediators of synaptic neuroprotection conferred by the slow Wallerian degeneration (Wlds) gene. Mol Cell Proteomics (2007) 1.35
CHCM1/CHCHD6, novel mitochondrial protein linked to regulation of mitofilin and mitochondrial cristae morphology. J Biol Chem (2012) 1.35
Uniform nomenclature for the mitochondrial contact site and cristae organizing system. J Cell Biol (2014) 1.34
Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes. Diabetes (2009) 1.33
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin. Proc Natl Acad Sci U S A (2010) 1.28
Plasticity in mitochondrial cristae density allows metabolic capacity modulation in human skeletal muscle. J Physiol (2016) 1.23
Sam50 functions in mitochondrial intermembrane space bridging and biogenesis of respiratory complexes. Mol Cell Biol (2012) 1.22
SOD1 targeted to the mitochondrial intermembrane space prevents motor neuropathy in the Sod1 knockout mouse. Brain (2010) 1.21
Membrane deformation under local pH gradient: mimicking mitochondrial cristae dynamics. Biophys J (2008) 1.15
A novel mitochondrial outer membrane protein, MOMA-1, that affects cristae morphology in Caenorhabditis elegans. Mol Biol Cell (2011) 1.12
Proteomic identification of dopamine-conjugated proteins from isolated rat brain mitochondria and SH-SY5Y cells. Neurobiol Dis (2009) 1.11
Identification of a novel protein MICS1 that is involved in maintenance of mitochondrial morphology and apoptotic release of cytochrome c. Mol Biol Cell (2008) 1.10
Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space. J Biol Chem (2012) 1.08
Trypanosoma cruzi infection induces a global host cell response in cardiomyocytes. Infect Immun (2011) 1.07
Identifying differential exon splicing using linear models and correlation coefficients. BMC Bioinformatics (2009) 1.05
APOOL is a cardiolipin-binding constituent of the Mitofilin/MINOS protein complex determining cristae morphology in mammalian mitochondria. PLoS One (2013) 1.05
The role of dopamine oxidation in mitochondrial dysfunction: implications for Parkinson's disease. J Bioenerg Biomembr (2009) 1.05
A robust method for quantitative high-throughput analysis of proteomes by 18O labeling. Mol Cell Proteomics (2010) 1.03
New insights into mitochondrial structure during cell death. Exp Neurol (2009) 1.01
The C-terminal domain of Fcj1 is required for formation of crista junctions and interacts with the TOB/SAM complex in mitochondria. Mol Biol Cell (2012) 1.00
DISC1 genetics, biology and psychiatric illness. Front Biol (Beijing) (2013) 1.00
Skeletal muscle proteomics: carbohydrate metabolism oscillates with seasonal and torpor-arousal physiology of hibernation. Am J Physiol Regul Integr Comp Physiol (2011) 0.99
Structural diversity of mitochondria: functional implications. Ann N Y Acad Sci (2008) 0.98
Dynamics of mitochondrial structure during apoptosis and the enigma of Opa1. Biochim Biophys Acta (2009) 0.96
Role of mitochondrial inner membrane organizing system in protein biogenesis of the mitochondrial outer membrane. Mol Biol Cell (2012) 0.96
Proteomic analysis of rat brain mitochondria following exposure to dopamine quinone: implications for Parkinson disease. Neurobiol Dis (2007) 0.95
Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genes. Front Genet (2015) 0.95
In vivo pathogenic role of mutant SOD1 localized in the mitochondrial intermembrane space. J Neurosci (2011) 0.94
Topological analysis of protein co-abundance networks identifies novel host targets important for HCV infection and pathogenesis. BMC Syst Biol (2012) 0.94
Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation. J Biol Chem (2011) 0.93
MITOCHIP assessment of differential gene expression in the skeletal muscle of Ant1 knockout mice: coordinate regulation of OXPHOS, antioxidant, and apoptotic genes. Biochim Biophys Acta (2008) 0.93
QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology. Elife (2015) 0.93
Compensatory proteome adjustments imply tissue-specific structural and metabolic reorganization following episodic hypoxia or anoxia in the epaulette shark (Hemiscyllium ocellatum). Physiol Genomics (2010) 0.92
The connection between inner membrane topology and mitochondrial function. J Mol Cell Cardiol (2013) 0.92
Mitochondrial configurations in peripheral nerve suggest differential ATP production. J Struct Biol (2010) 0.91
Protein interactions of phosphatase and tensin homologue (PTEN) and its cancer-associated G20E mutant compared by using stable isotope labeling by amino acids in cell culture-based parallel affinity purification. J Biol Chem (2011) 0.90
Inhibition of oxidative stress by coenzyme Q10 increases mitochondrial mass and improves bioenergetic function in optic nerve head astrocytes. Cell Death Dis (2013) 0.89
Adenine nucleotide translocase-1 induces cardiomyocyte death through upregulation of the pro-apoptotic protein Bax. J Mol Cell Cardiol (2009) 0.89
The mitochondrial amidoxime-reducing component (mARC1) is a novel signal-anchored protein of the outer mitochondrial membrane. J Biol Chem (2012) 0.89
Cloning and functional analysis of FLJ20420: a novel transcription factor for the BAG-1 promoter. PLoS One (2012) 0.89
Structural determinants of PINK1 topology and dual subcellular distribution. BMC Cell Biol (2010) 0.88
FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria. EMBO Rep (2016) 0.88
Detailed analysis of the human mitochondrial contact site complex indicate a hierarchy of subunits. PLoS One (2015) 0.88
Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice. Mol Cell Proteomics (2013) 0.87
Aim24 and MICOS modulate respiratory function, tafazzin-related cardiolipin modification and mitochondrial architecture. Elife (2014) 0.86
Proteins that fuse and fragment mitochondria in apoptosis: con-fissing a deadly con-fusion? J Bioenerg Biomembr (2005) 0.86
Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling. J Cell Biol (2016) 0.86
Trypanosoma cruzi response to sterol biosynthesis inhibitors: morphophysiological alterations leading to cell death. PLoS One (2013) 0.86
Mitochonic Acid 5 Binds Mitochondria and Ameliorates Renal Tubular and Cardiac Myocyte Damage. J Am Soc Nephrol (2015) 0.85
Ultrastructure of Cosmarium strains (Zygnematophyceae, Streptophyta) collected from various geographic locations shows species-specific differences both at optimal and stress temperatures. Protoplasma (2014) 0.84
Role of membrane contact sites in protein import into mitochondria. Protein Sci (2015) 0.84
Mitofilin and CHCHD6 physically interact with Sam50 to sustain cristae structure. Sci Rep (2015) 0.83
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death Differ (2015) 0.82
A Novel Role for Progesterone Receptor Membrane Component 1 (PGRMC1): A Partner and Regulator of Ferrochelatase. Biochemistry (2016) 0.81
CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis. EMBO Mol Med (2015) 0.81
Fatigue-related gene networks identified in CD(14)+ cells isolated from HIV-infected patients: part I: research findings. Biol Res Nurs (2013) 0.81
Effects of (-)-epicatechin and derivatives on nitric oxide mediated induction of mitochondrial proteins. Bioorg Med Chem Lett (2013) 0.80
Global changes in the rat heart proteome induced by prolonged morphine treatment and withdrawal. PLoS One (2012) 0.80
Mitochondrial dynamics in diabetic cardiomyopathy. Antioxid Redox Signal (2015) 0.79
Human Mitochondrial DNA-Protein Complexes Attach to a Cholesterol-Rich Membrane Structure. Sci Rep (2015) 0.79
Mitochondrial hepato-encephalopathy due to deficiency of QIL1/MIC13 (C19orf70), a MICOS complex subunit. Eur J Hum Genet (2016) 0.78
Cox17 Protein Is an Auxiliary Factor Involved in the Control of the Mitochondrial Contact Site and Cristae Organizing System. J Biol Chem (2015) 0.78
The evolution of MICOS: Ancestral and derived functions and interactions. Commun Integr Biol (2015) 0.78
Neurobiology of axonal transport defects in motor neuron diseases: Opportunities for translational research? Neurobiol Dis (2017) 0.77
The Spectrum of Mitochondrial Ultrastructural Defects in Mitochondrial Myopathy. Sci Rep (2016) 0.77
A splicing mutation in the novel mitochondrial protein DNAJC11 causes motor neuron pathology associated with cristae disorganization, and lymphoid abnormalities in mice. PLoS One (2014) 0.77
Respiratory supercomplexes: plasticity and implications. Front Biosci (Landmark Ed) (2015) 0.77
Suppression of Mic60 compromises mitochondrial transcription and oxidative phosphorylation. Sci Rep (2015) 0.77
Vitamin A dimers trigger the protracted death of retinal pigment epithelium cells. Cell Death Dis (2014) 0.77
Mic60/mitofilin overexpression alters mitochondrial dynamics and attenuates vulnerability of dopaminergic cells to dopamine and rotenone. Neurobiol Dis (2016) 0.76
The Oxidation Status of Mic19 Regulates MICOS Assembly. Mol Cell Biol (2015) 0.76
Lost region in amyloid precursor protein (APP) through TALEN-mediated genome editing alters mitochondrial morphology. Sci Rep (2016) 0.76
Mic13 Is Essential for Formation of Crista Junctions in Mammalian Cells. PLoS One (2016) 0.76
QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease. Elife (2016) 0.75
An evidence based hypothesis on the existence of two pathways of mitochondrial crista formation. Elife (2016) 0.75
The MICOS component Mic60 displays a conserved membrane-bending activity that is necessary for normal cristae morphology. J Cell Biol (2017) 0.75
Optic Atrophy 1 Is Epistatic to the Core MICOS Component MIC60 in Mitochondrial Cristae Shape Control. Cell Rep (2016) 0.75
Elevated Energy Production in Chronic Fatigue Syndrome Patients. J Nat Sci (2016) 0.75
Infection with Plasmodium berghei ookinetes alters protein expression in the brain of Anopheles albimanus mosquitoes. Parasit Vectors (2016) 0.75
Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2. PLoS One (2015) 0.75
A new survivin tracer tracks, delocalizes and captures endogenous survivin at different subcellular locations and in distinct organelles. Sci Rep (2016) 0.75
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature (2001) 57.23
A novel genetic system to detect protein-protein interactions. Nature (1989) 43.83
Genomic libraries and a host strain designed for highly efficient two-hybrid selection in yeast. Genetics (1996) 24.62
SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J Struct Biol (1996) 22.89
Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form. Anal Biochem (1991) 12.68
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol (1992) 11.24
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development. J Cell Biol (2003) 10.10
The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant. Nat Cell Biol (2000) 9.87
Dynamin-related protein Drp1 is required for mitochondrial division in mammalian cells. Mol Biol Cell (2001) 9.67
Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining. J Cell Biol (1975) 8.68
Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy. Nat Genet (2000) 7.40
OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28. Nat Genet (2000) 7.20
Ultrastructural bases for metabolically linked mechanical activity in mitochondria. I. Reversible ultrastructural changes with change in metabolic steady state in isolated liver mitochondria. J Cell Biol (1966) 6.71
C. elegans dynamin-related protein DRP-1 controls severing of the mitochondrial outer membrane. Mol Cell (1999) 6.14
Characterization of the human heart mitochondrial proteome. Nat Biotechnol (2003) 5.66
Loss of OPA1 perturbates the mitochondrial inner membrane structure and integrity, leading to cytochrome c release and apoptosis. J Biol Chem (2002) 5.61
Division versus fusion: Dnm1p and Fzo1p antagonistically regulate mitochondrial shape. J Cell Biol (1999) 5.53
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. Dev Cell (2002) 5.45
Mitochondrial fusion in yeast requires the transmembrane GTPase Fzo1p. J Cell Biol (1998) 5.21
Developmentally regulated mitochondrial fusion mediated by a conserved, novel, predicted GTPase. Cell (1997) 5.13
Alpha-helical coiled coils and bundles: how to design an alpha-helical protein. Proteins (1990) 4.91
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med (1995) 4.88
The dynamin-related GTPase, Dnm1p, controls mitochondrial morphology in yeast. J Cell Biol (1998) 4.72
The machinery of mitochondrial inheritance and behavior. Science (1999) 3.82
Mitochondrial protein import. Biochim Biophys Acta (1989) 3.66
Noise reduction in electron tomographic reconstructions using nonlinear anisotropic diffusion. J Struct Biol (2001) 3.38
The ATP synthase is involved in generating mitochondrial cristae morphology. EMBO J (2002) 3.35
Mitochondrial dynamics and division in budding yeast. Trends Cell Biol (2002) 3.15
The dynamin-related GTPase, Mgm1p, is an intermembrane space protein required for maintenance of fusion competent mitochondria. J Cell Biol (2000) 3.14
Three-dimensional reconstruction of imperfect two-dimensional crystals. Ultramicroscopy (1984) 2.55
Mgm1p, a dynamin-related GTPase, is essential for fusion of the mitochondrial outer membrane. Mol Biol Cell (2003) 2.49
The intramitochondrial dynamin-related GTPase, Mgm1p, is a component of a protein complex that mediates mitochondrial fusion. J Cell Biol (2003) 2.45
Mmm1p, a mitochondrial outer membrane protein, is connected to mitochondrial DNA (mtDNA) nucleoids and required for mtDNA stability. J Cell Biol (2001) 2.28
Yeast mitochondrial dynamics: fusion, division, segregation, and shape. Microsc Res Tech (2000) 1.89
Use of polarography to detect respiration defects in cell cultures. Methods Enzymol (1996) 1.86
The many shapes of mitochondrial membranes. Traffic (2001) 1.71
Tim23 links the inner and outer mitochondrial membranes. Cell (2000) 1.68
Mitochondrial protein import: involvement of the mature part of a cleavable precursor protein in the binding to receptor sites. EMBO J (1987) 1.63
Fo membrane domain of ATP synthase from bovine heart mitochondria: purification, subunit composition, and reconstitution with F1-ATPase. Biochemistry (1994) 1.49
A comparison of [9,10-3H]palmitic and [9,10-3H]myristic acids for the detection of defects of fatty acid oxidation in intact cultured fibroblasts. J Inherit Metab Dis (1990) 1.43
Molecular characterization of mitofilin (HMP), a mitochondria-associated protein with predicted coiled coil and intermembrane space targeting domains. J Cell Sci (1996) 1.23
The inner membrane protein Mdm33 controls mitochondrial morphology in yeast. J Cell Biol (2003) 1.22
Identification of subunit g of yeast mitochondrial F1F0-ATP synthase, a protein required for maximal activity of cytochrome c oxidase. Eur J Biochem (1999) 1.21
Large-scale chromatographic purification of F1F0-ATPase and complex I from bovine heart mitochondria. Biochem J (1996) 1.11
Mitofilin is a transmembrane protein of the inner mitochondrial membrane expressed as two isoforms. Exp Cell Res (1997) 1.10
Insertion of an uncharged polypeptide into the mitochondrial inner membrane does not require a trans-bilayer electrochemical potential: effects of positive charges. Biochim Biophys Acta (1995) 1.04
A novel human gene that is preferentially transcribed in heart muscle. Gene (1994) 0.94
Deranged hypothetical proteins Rik protein, Nit protein 2 and mitochondrial inner membrane protein, Mitofilin, in fetal Down syndrome brain. Cell Mol Biol (Noisy-le-grand) (2003) 0.89
Gerbils of a seizure-sensitive strain have a mitochondrial inner membrane protein with different isoelectric points from those of a seizure-resistant strain. Electrophoresis (2002) 0.84
The diploid genome sequence of an Asian individual. Nature (2008) 46.29
A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78
Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med (2003) 26.05
The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev (2007) 13.05
Diverse somatic mutation patterns and pathway alterations in human cancers. Nature (2010) 10.83
TEAD mediates YAP-dependent gene induction and growth control. Genes Dev (2008) 9.88
Regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol (2008) 8.92
The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19
An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94
ZDOCK: an initial-stage protein-docking algorithm. Proteins (2003) 7.52
Gene discovery and annotation using LCM-454 transcriptome sequencing. Genome Res (2006) 7.10
The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08
A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum Mol Genet (2003) 6.82
Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res (2003) 6.19
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev (2010) 6.05
SNP discovery via 454 transcriptome sequencing. Plant J (2007) 5.92
MicroRNA-mediated conversion of human fibroblasts to neurons. Nature (2011) 5.59
A reserve stem cell population in small intestine renders Lgr5-positive cells dispensable. Nature (2011) 5.45
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis. Dev Cell (2002) 5.45
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev (2010) 5.38
Structural and functional features and significance of the physical linkage between ER and mitochondria. J Cell Biol (2006) 5.37
The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30
Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol (2013) 5.21
A porous supramolecular architecture from a copper(II) coordination polymer with a 3D four-connected 8(6) net. Inorg Chem (2003) 5.16
Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09
Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 4.95
Stability of the regulatory T cell lineage in vivo. Science (2010) 4.89
Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med (2007) 4.80
Therapeutic antibody targeting of individual Notch receptors. Nature (2010) 4.56
The Plasmodium genome database. Nature (2002) 4.36
The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus. J Clin Invest (2002) 4.22
Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood (2003) 3.98
Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr (2004) 3.96
Germline gain-of-function mutations in SOS1 cause Noonan syndrome. Nat Genet (2006) 3.81
Multiple organ pathology, metabolic abnormalities and impaired homeostasis of reactive oxygen species in Epas1-/- mice. Nat Genet (2003) 3.78
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol (2006) 3.75
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev (2012) 3.48
ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res (2003) 3.24
Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev (2011) 3.15
Somatic mutations lead to an oncogenic deletion of met in lung cancer. Cancer Res (2006) 3.12
A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol (2010) 3.09
Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains. Mol Cell (2012) 3.08
Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol (2003) 3.02
Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype. Virology (2002) 2.96
Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91
Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity (2004) 2.89
Requirement for coronin 1 in T lymphocyte trafficking and cellular homeostasis. Science (2006) 2.85
Oncogenic BRAF is required for tumor growth and maintenance in melanoma models. Cancer Res (2006) 2.84
Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity (2009) 2.84
Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol (2009) 2.84
Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res (2011) 2.71
A highly sensitive CMOS digital Hall sensor for low magnetic field applications. Sensors (Basel) (2012) 2.69
Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. Blood (2006) 2.69
Mutations in myosin light chain kinase cause familial aortic dissections. Am J Hum Genet (2010) 2.67
Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers. Mol Cancer Res (2009) 2.65
Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system. Proc Natl Acad Sci U S A (2005) 2.65
Evaluation of the impact of hepatitis B vaccination among children born during 1992-2005 in China. J Infect Dis (2009) 2.62
A review of EPAP nasal device therapy for obstructive sleep apnea syndrome. Sleep Breath (2014) 2.61
Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection. Nat Med (2004) 2.59
The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol (2008) 2.57
Noninvasive characterization of epicardial activation in humans with diverse atrial fibrillation patterns. Circulation (2010) 2.57
A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun (2005) 2.55
Bad-deficient mice develop diffuse large B cell lymphoma. Proc Natl Acad Sci U S A (2003) 2.54
Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes. Kidney Int (2011) 2.50
AILUN: reannotating gene expression data automatically. Nat Methods (2007) 2.47
High-resolution genomic and expression analyses of copy number alterations in breast tumors. Genes Chromosomes Cancer (2008) 2.46
1,1'-[(Hexane-1,6-diyldi-oxy)bis-(nitrilo-methyl-idyne)]dinaphthalene. Acta Crystallogr Sect E Struct Rep Online (2008) 2.45
The ciliary G-protein-coupled receptor Gpr161 negatively regulates the Sonic hedgehog pathway via cAMP signaling. Cell (2013) 2.42
Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med (2005) 2.42
Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney. Am J Physiol Renal Physiol (2006) 2.39
Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification. J Clin Oncol (2011) 2.38
Diethyl 3,8-dimethyl-4,7-diazadeca-2,8-dienedioate. Acta Crystallogr C (2004) 2.38
HIV/STD stigmatization fears as health-seeking barriers in China. AIDS Behav (2006) 2.37
PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished). Nucleic Acids Res (2002) 2.37
MetMAb, the one-armed 5D5 anti-c-Met antibody, inhibits orthotopic pancreatic tumor growth and improves survival. Cancer Res (2008) 2.33
Inflammation in acute kidney injury. Nephron Exp Nephrol (2008) 2.32
Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial. Lancet Neurol (2011) 2.27
Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci U S A (2007) 2.27
Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice. Arterioscler Thromb Vasc Biol (2011) 2.27
TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell (2008) 2.26
2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl N-ethyl-carbamate. Acta Crystallogr Sect E Struct Rep Online (2009) 2.24
Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. J Immunol (2006) 2.22
Durable complete response of metastatic gastric cancer with anti-Met therapy followed by resistance at recurrence. Cancer Discov (2011) 2.22
Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury. J Am Soc Nephrol (2009) 2.18
The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell (2012) 2.17
Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging. Proc Natl Acad Sci U S A (2008) 2.16
Expression of tumor-associated antigens in acute myeloid leukemia: Implications for specific immunotherapeutic approaches. Blood (2006) 2.14
Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials (2009) 2.13
Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks. Circ Res (2005) 2.11
Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. Sci Transl Med (2011) 2.10
Increased expression of CYP17 and CYP11B1 in subclinical Cushing's syndrome due to adrenal adenomas. Int J Urol (2011) 2.07
A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis. Nat Genet (2011) 2.05
Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line. Invest Ophthalmol Vis Sci (2005) 2.02
Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes. Am J Med (2012) 2.02
Sexually transmitted disease prevalence and characteristics of market vendors in eastern China. Sex Transm Dis (2003) 2.02