Inflammation in acute kidney injury.

PubWeight™: 2.32‹?› | Rank: Top 2%

🔗 View Article (PMC 2614446)

Published in Nephron Exp Nephrol on September 18, 2008

Authors

Gilbert R Kinsey1, Li Li, Mark D Okusa

Author Affiliations

1: Division of Nephrology and Center for Immunity, Inflammation and Regenerative Medicine, University of Virginia, Charlottesville, VA 22908, USA.

Associated clinical trials:

Pirfenidone Effect on the Recovery of Renal Function in Septic Acute Kidney Injury (AKI) | NCT02530359

Articles citing this

IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury. J Clin Invest (2009) 3.30

Acute kidney injury: a springboard for progression in chronic kidney disease. Am J Physiol Renal Physiol (2010) 3.25

Acute kidney injury in childhood: should we be worried about progression to CKD? Pediatr Nephrol (2010) 2.00

Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury. J Clin Invest (2012) 2.00

CSF-1 signaling mediates recovery from acute kidney injury. J Clin Invest (2012) 1.98

Inflammation and coagulation markers and kidney function decline: the Multi-Ethnic Study of Atherosclerosis (MESA). Am J Kidney Dis (2012) 1.79

Ultrasound prevents renal ischemia-reperfusion injury by stimulating the splenic cholinergic anti-inflammatory pathway. J Am Soc Nephrol (2013) 1.76

Macrophages, dendritic cells, and kidney ischemia-reperfusion injury. Semin Nephrol (2010) 1.74

The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats. Intensive Care Med (2011) 1.72

Genetic deficiency of adiponectin protects against acute kidney injury. Kidney Int (2013) 1.71

Fresh and cryopreserved, uncultured adipose tissue-derived stem and regenerative cells ameliorate ischemia-reperfusion-induced acute kidney injury. Nephrol Dial Transplant (2010) 1.70

Pathophysiology of acute kidney injury. Compr Physiol (2012) 1.56

Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury. Kidney Int (2010) 1.22

Searching for mechanisms that matter in early septic acute kidney injury: an experimental study. Crit Care (2011) 1.19

Deletion of the epidermal growth factor receptor in renal proximal tubule epithelial cells delays recovery from acute kidney injury. Kidney Int (2012) 1.17

Evidence for a novel human-specific xeno-auto-antibody response against vascular endothelium. Blood (2009) 1.16

Nod1 and nod2 are expressed in human and murine renal tubular epithelial cells and participate in renal ischemia reperfusion injury. J Immunol (2010) 1.13

Diagnostic value of urine sTREM-1 for sepsis and relevant acute kidney injuries: a prospective study. Crit Care (2011) 1.12

Acidosis activation of the proton-sensing GPR4 receptor stimulates vascular endothelial cell inflammatory responses revealed by transcriptome analysis. PLoS One (2013) 1.09

Preconditioning with physiological levels of ethanol protect kidney against ischemia/reperfusion injury by modulating oxidative stress. PLoS One (2011) 1.04

Netrin-1 regulates the inflammatory response of neutrophils and macrophages, and suppresses ischemic acute kidney injury by inhibiting COX-2-mediated PGE2 production. Kidney Int (2013) 1.04

Heart-kidney crosstalk and role of humoral signaling in critical illness. Crit Care (2014) 1.02

Temporary perioperative decline of renal function is an independent predictor for chronic kidney disease. Clin J Am Soc Nephrol (2010) 1.02

Invariant natural killer T cells and TGF-beta attenuate anti-GBM glomerulonephritis. J Am Soc Nephrol (2009) 1.01

Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury. Kidney Int (2013) 0.99

Macrophages mediate lung inflammation in a mouse model of ischemic acute kidney injury. Am J Physiol Renal Physiol (2011) 0.98

Renal hypoperfusion and impaired endothelium-dependent vasodilation in an animal model of VILI: the role of the peroxynitrite-PARP pathway. Crit Care (2010) 0.98

Pathogenesis of acute kidney injury: foundation for clinical practice. Am J Kidney Dis (2011) 0.98

IRF-1 promotes inflammation early after ischemic acute kidney injury. J Am Soc Nephrol (2009) 0.96

Renal endothelial dysfunction in acute kidney ischemia reperfusion injury. Cardiovasc Hematol Disord Drug Targets (2014) 0.96

Amelioration of acute kidney injury in lipopolysaccharide-induced systemic inflammatory response syndrome by an aldose reductase inhibitor, fidarestat. PLoS One (2012) 0.95

Inflammation in AKI: Current Understanding, Key Questions, and Knowledge Gaps. J Am Soc Nephrol (2015) 0.95

T Lymphocyte-Specific Activation of Nrf2 Protects from AKI. J Am Soc Nephrol (2015) 0.92

Early and prominent alterations in hemodynamics, signaling, and gene expression following renal ischemia in sickle cell disease. Am J Physiol Renal Physiol (2010) 0.92

The aging kidney: increased susceptibility to nephrotoxicity. Int J Mol Sci (2014) 0.92

Semaphorin 3A inactivation suppresses ischemia-reperfusion-induced inflammation and acute kidney injury. Am J Physiol Renal Physiol (2014) 0.91

Selective deletion of the endothelial sphingosine-1-phosphate 1 receptor exacerbates kidney ischemia-reperfusion injury. Kidney Int (2013) 0.89

Rhein prevents endotoxin-induced acute kidney injury by inhibiting NF-κB activities. Sci Rep (2015) 0.88

Adrenocorticotropic hormone ameliorates acute kidney injury by steroidogenic-dependent and -independent mechanisms. Kidney Int (2013) 0.88

Downregulation of cystathionine β-synthase and cystathionine γ-lyase expression stimulates inflammation in kidney ischemia-reperfusion injury. Physiol Rep (2014) 0.86

Hydroxyfasudil-mediated inhibition of ROCK1 and ROCK2 improves kidney function in rat renal acute ischemia-reperfusion injury. PLoS One (2011) 0.86

Activation of the miR-17 family and miR-21 during murine kidney ischemia-reperfusion injury. Nucleic Acid Ther (2013) 0.86

Metformin Protects Against Cisplatin-Induced Tubular Cell Apoptosis and Acute Kidney Injury via AMPKα-regulated Autophagy Induction. Sci Rep (2016) 0.85

Inflammation and microvasculopathy in renal ischemia reperfusion injury. J Transplant (2012) 0.85

Brain-kidney crosstalk. Crit Care (2014) 0.85

Hepcidin Mitigates Renal Ischemia-Reperfusion Injury by Modulating Systemic Iron Homeostasis. J Am Soc Nephrol (2015) 0.84

Expanding role of T cells in acute kidney injury. Curr Opin Nephrol Hypertens (2014) 0.84

Renal ischaemia reperfusion injury: a mouse model of injury and regeneration. J Vis Exp (2014) 0.84

Acute kidney injury: a conspiracy of Toll-like receptor 4 on endothelia, leukocytes, and tubules. Pediatr Nephrol (2011) 0.83

Macrophage dynamics in AKI to CKD progression. J Am Soc Nephrol (2013) 0.83

LPS-induced genes in intestinal tissue of the sea cucumber Holothuria glaberrima. PLoS One (2009) 0.83

Licochalcone A Attenuates Lipopolysaccharide-Induced Acute Kidney Injury by Inhibiting NF-κB Activation. Inflammation (2016) 0.82

The Role of M2 Macrophages in the Progression of Chronic Kidney Disease following Acute Kidney Injury. PLoS One (2015) 0.82

Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int (2015) 0.82

14S,21R-dihydroxy-docosahexaenoic acid treatment enhances mesenchymal stem cell amelioration of renal ischemia/reperfusion injury. Stem Cells Dev (2011) 0.82

Reactive oxygen species and IRF1 stimulate IFNα production by proximal tubules during ischemic AKI. Am J Physiol Renal Physiol (2013) 0.82

Guidance cue netrin-1 and the regulation of inflammation in acute and chronic kidney disease. Mediators Inflamm (2014) 0.81

Endothelium injury and inflammatory state during abdominal aortic aneurysm surgery: scrutinizing the very early and minute injurious effects using endothelial markers - a pilot study. Arch Med Sci (2013) 0.81

Role of Netrin-1 Beyond the Brain: From Biomarker of Tissue Injury to Therapy for Inflammatory Diseases. Recent Pat Biomark (2012) 0.81

Overexpression of cGMP-dependent protein kinase I (PKG-I) attenuates ischemia-reperfusion-induced kidney injury. Am J Physiol Renal Physiol (2011) 0.81

Tumor necrosis factor alpha promoter polymorphism and severity of acute kidney injury. Nephron Clin Pract (2013) 0.80

Cytoprotection behind heme oxygenase-1 in renal diseases. World J Nephrol (2012) 0.80

Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway. Oncotarget (2016) 0.80

Oxidative stress: dual pathway induction in cardiorenal syndrome type 1 pathogenesis. Oxid Med Cell Longev (2015) 0.80

Endothelial Krüppel-Like Factor 4 Mediates the Protective Effect of Statins against Ischemic AKI. J Am Soc Nephrol (2015) 0.79

Dialysis-requiring acute kidney injury increases risk of long-term malignancy: a population-based study. J Cancer Res Clin Oncol (2014) 0.79

Use of laser capture microdissection for the assessment of equine lamellar basal epithelial cell signalling in the early stages of laminitis. Equine Vet J (2014) 0.79

Both IL-1β and TNF-α regulate NGAL expression in polymorphonuclear granulocytes of chronic hemodialysis patients. Mediators Inflamm (2011) 0.79

The long noncoding RNA landscape in hypoxic and inflammatory renal epithelial injury. Am J Physiol Renal Physiol (2015) 0.78

Adenosine receptors and renal ischaemia reperfusion injury. Acta Physiol (Oxf) (2014) 0.78

Advances in the pathogenesis of cardiorenal syndrome type 3. Oxid Med Cell Longev (2015) 0.78

The reduction of Na/H exchanger-3 protein and transcript expression in acute ischemia-reperfusion injury is mediated by extractable tissue factor(s). Kidney Int (2011) 0.78

Tubular Epithelial NF-κB Activity Regulates Ischemic AKI. J Am Soc Nephrol (2016) 0.77

Induction of proinflammatory cytokines and nitric oxide by Trypanosoma cruzi in renal cells. Parasitol Res (2011) 0.76

The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis. Clin J Am Soc Nephrol (2015) 0.76

Sickle cell disease (SCD), iNKT cells, and regadenoson infusion. Trans Am Clin Climatol Assoc (2012) 0.76

Long-term sequelae from acute kidney injury: potential mechanisms for the observed poor renal outcomes. Crit Care (2015) 0.76

Role of Paricalcitol in Modulating the Immune Response in Patients with Renal Disease. Int J Endocrinol (2015) 0.76

Protective effect of indomethacin in renal ischemia-reperfusion injury in mice. J Zhejiang Univ Sci B (2014) 0.76

A Multi-Center, Randomized, Controlled, Pivotal Study to Assess the Safety and Efficacy of a Selective Cytopheretic Device in Patients with Acute Kidney Injury. PLoS One (2015) 0.76

Human endometrial regenerative cells attenuate renal ischemia reperfusion injury in mice. J Transl Med (2016) 0.76

Effect of perioperative sodium bicarbonate administration on renal function following cardiac surgery for infective endocarditis: a randomized, placebo-controlled trial. Crit Care (2017) 0.75

Growth arrest-specific protein 6 protects against renal ischemia-reperfusion injury. J Surg Res (2015) 0.75

Apoptotic cell administration is detrimental in murine renal ischaemia reperfusion injury. J Inflamm (Lond) (2014) 0.75

The Complex Relationship of Extracorporeal Membrane Oxygenation and Acute Kidney Injury: Causation or Association? Biomed Res Int (2016) 0.75

Sesamin protects against renal ischemia reperfusion injury by promoting CD39-adenosine-A2AR signal pathway in mice. Am J Transl Res (2016) 0.75

Heme Oxygenase 1 as a Therapeutic Target in Acute Kidney Injury. Am J Kidney Dis (2017) 0.75

Research Progress on Regulatory T Cells in Acute Kidney Injury. J Immunol Res (2015) 0.75

Acute kidney injury increases the risk of end-stage renal disease after cardiac surgery in an Asian population: a prospective cohort study. BMC Nephrol (2017) 0.75

Osthole protects sepsis-induced acute kidney injury via down-regulating NF-κB signal pathway. Oncotarget (2016) 0.75

Acute Kidney Injury as a Risk Factor for Delirium and Coma during Critical Illness. Am J Respir Crit Care Med (2016) 0.75

Articles cited by this

Acute renal failure. N Engl J Med (1996) 8.83

TLR4 activation mediates kidney ischemia/reperfusion injury. J Clin Invest (2007) 4.77

Intercellular adhesion molecule-1-deficient mice are protected against ischemic renal injury. J Clin Invest (1996) 3.73

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney. J Clin Invest (2005) 3.48

Resident dendritic cells are the predominant TNF-secreting cell in early renal ischemia-reperfusion injury. Kidney Int (2007) 2.98

NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury. J Immunol (2007) 2.92

Identification of the CD4(+) T cell as a major pathogenic factor in ischemic acute renal failure. J Clin Invest (2001) 2.79

Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney. Am J Physiol Renal Physiol (2006) 2.39

TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways. J Immunol (2007) 2.32

Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol (2004) 2.27

Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. J Immunol (2006) 2.22

Injury of the renal microvascular endothelium alters barrier function after ischemia. Am J Physiol Renal Physiol (2003) 2.19

Maladaptive role of IL-6 in ischemic acute renal failure. J Am Soc Nephrol (2005) 2.07

Endothelial dysfunction in ischemic acute renal failure: rescue by transplanted endothelial cells. Am J Physiol Renal Physiol (2002) 1.85

B cell deficiency confers protection from renal ischemia reperfusion injury. J Immunol (2003) 1.73

Fractalkine receptor (CX3CR1) inhibition is protective against ischemic acute renal failure in mice. Am J Physiol Renal Physiol (2007) 1.59

Altered renal tubular expression of the complement inhibitor Crry permits complement activation after ischemia/reperfusion. J Clin Invest (2006) 1.57

Antigen presentation by dendritic cells in renal lymph nodes is linked to systemic and local injury to the kidney. Kidney Int (2005) 1.52

Injury in renal ischemia-reperfusion is independent from immunoglobulins and T lymphocytes. Am J Physiol Renal Physiol (2002) 1.45

C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion. J Immunol (2007) 1.45

An evaluation of the neutrophil as a mediator of in vivo renal ischemic-reperfusion injury. Am J Pathol (1989) 1.23

Effects of combined T- and B-cell deficiency on murine ischemia reperfusion injury. Am J Transplant (2005) 1.16

Articles by these authors

The diploid genome sequence of an Asian individual. Nature (2008) 46.29

A draft sequence of the rice genome (Oryza sativa L. ssp. indica). Science (2002) 42.78

Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med (2003) 26.05

The sequence and de novo assembly of the giant panda genome. Nature (2009) 15.76

Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control. Genes Dev (2007) 13.05

Diverse somatic mutation patterns and pathway alterations in human cancers. Nature (2010) 10.83

TEAD mediates YAP-dependent gene induction and growth control. Genes Dev (2008) 9.88

Regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol (2008) 8.92

The genome of the cucumber, Cucumis sativus L. Nat Genet (2009) 8.19

An abundance of rare functional variants in 202 drug target genes sequenced in 14,002 people. Science (2012) 7.94

ZDOCK: an initial-stage protein-docking algorithm. Proteins (2003) 7.52

Gene discovery and annotation using LCM-454 transcriptome sequencing. Genome Res (2006) 7.10

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models. Nat Biotechnol (2010) 7.08

A long-range Shh enhancer regulates expression in the developing limb and fin and is associated with preaxial polydactyly. Hum Mol Genet (2003) 6.82

Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination. Vaccine (2009) 6.30

PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data. Nucleic Acids Res (2003) 6.19

The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version. Genes Dev (2010) 6.05

SNP discovery via 454 transcriptome sequencing. Plant J (2007) 5.92

MicroRNA-mediated conversion of human fibroblasts to neurons. Nature (2011) 5.59

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP). Genes Dev (2010) 5.38

The oyster genome reveals stress adaptation and complexity of shell formation. Nature (2012) 5.30

A porous supramolecular architecture from a copper(II) coordination polymer with a 3D four-connected 8(6) net. Inorg Chem (2003) 5.16

Candidate single-nucleotide polymorphisms from a genomewide association study of Alzheimer disease. Arch Neurol (2007) 5.09

Immune recognition of Pseudomonas aeruginosa mediated by the IPAF/NLRC4 inflammasome. J Exp Med (2007) 4.95

Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol (2005) 4.92

Stability of the regulatory T cell lineage in vivo. Science (2010) 4.89

Identification of tendon stem/progenitor cells and the role of the extracellular matrix in their niche. Nat Med (2007) 4.80

The Plasmodium genome database. Nature (2002) 4.36

Cytokines and BMP-4 promote hematopoietic differentiation of human embryonic stem cells. Blood (2003) 3.98

Increased consumption of refined carbohydrates and the epidemic of type 2 diabetes in the United States: an ecologic assessment. Am J Clin Nutr (2004) 3.96

Germline gain-of-function mutations in SOS1 cause Noonan syndrome. Nat Genet (2006) 3.81

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial. Genome Biol (2006) 3.75

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis. Genes Dev (2012) 3.48

IL-17 produced by neutrophils regulates IFN-gamma-mediated neutrophil migration in mouse kidney ischemia-reperfusion injury. J Clin Invest (2009) 3.30

The chemokine receptors CCR2 and CX3CR1 mediate monocyte/macrophage trafficking in kidney ischemia-reperfusion injury. Kidney Int (2008) 3.30

ToxoDB: accessing the Toxoplasma gondii genome. Nucleic Acids Res (2003) 3.24

Angiomotin is a novel Hippo pathway component that inhibits YAP oncoprotein. Genes Dev (2011) 3.15

A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol (2010) 3.09

Gene density, transcription, and insulators contribute to the partition of the Drosophila genome into physical domains. Mol Cell (2012) 3.08

Bone marrow-derived stem cells initiate pancreatic regeneration. Nat Biotechnol (2003) 3.02

Mouse neuroinvasive phenotype of West Nile virus strains varies depending upon virus genotype. Virology (2002) 2.96

NKT cell activation mediates neutrophil IFN-gamma production and renal ischemia-reperfusion injury. J Immunol (2007) 2.92

Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis. Lancet Oncol (2012) 2.91

Endothelial and hematopoietic cell fate of human embryonic stem cells originates from primitive endothelium with hemangioblastic properties. Immunity (2004) 2.89

Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. Immunity (2009) 2.84

Increased intratumoral IL-17-producing cells correlate with poor survival in hepatocellular carcinoma patients. J Hepatol (2009) 2.84

Androgen deprivation causes epithelial-mesenchymal transition in the prostate: implications for androgen-deprivation therapy. Cancer Res (2011) 2.71

A highly sensitive CMOS digital Hall sensor for low magnetic field applications. Sensors (Basel) (2012) 2.69

Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. Blood (2006) 2.69

Mutations in myosin light chain kinase cause familial aortic dissections. Am J Hum Genet (2010) 2.67

Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers. Mol Cancer Res (2009) 2.65

Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system. Proc Natl Acad Sci U S A (2005) 2.65

Evaluation of the impact of hepatitis B vaccination among children born during 1992-2005 in China. J Infect Dis (2009) 2.62

A review of EPAP nasal device therapy for obstructive sleep apnea syndrome. Sleep Breath (2014) 2.61

Role of ISG15 protease UBP43 (USP18) in innate immunity to viral infection. Nat Med (2004) 2.59

The antioxidant defense system Keap1-Nrf2 comprises a multiple sensing mechanism for responding to a wide range of chemical compounds. Mol Cell Biol (2008) 2.57

Noninvasive characterization of epicardial activation in humans with diverse atrial fibrillation patterns. Circulation (2010) 2.57

A Kir2.1 gain-of-function mutation underlies familial atrial fibrillation. Biochem Biophys Res Commun (2005) 2.55

The mitochondrial inner membrane protein mitofilin controls cristae morphology. Mol Biol Cell (2005) 2.53

Progressive histological damage in renal allografts is associated with expression of innate and adaptive immunity genes. Kidney Int (2011) 2.50

AILUN: reannotating gene expression data automatically. Nat Methods (2007) 2.47

High-resolution genomic and expression analyses of copy number alterations in breast tumors. Genes Chromosomes Cancer (2008) 2.46

1,1'-[(Hexane-1,6-diyldi-oxy)bis-(nitrilo-methyl-idyne)]dinaphthalene. Acta Crystallogr Sect E Struct Rep Online (2008) 2.45

Generation of hematopoietic repopulating cells from human embryonic stem cells independent of ectopic HOXB4 expression. J Exp Med (2005) 2.42

Selective sphingosine 1-phosphate 1 receptor activation reduces ischemia-reperfusion injury in mouse kidney. Am J Physiol Renal Physiol (2006) 2.39

Phase II, open-label, single-arm trial of imatinib mesylate in patients with metastatic melanoma harboring c-Kit mutation or amplification. J Clin Oncol (2011) 2.38

Diethyl 3,8-dimethyl-4,7-diazadeca-2,8-dienedioate. Acta Crystallogr C (2004) 2.38

HIV/STD stigmatization fears as health-seeking barriers in China. AIDS Behav (2006) 2.37

PlasmoDB: the Plasmodium genome resource. An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished). Nucleic Acids Res (2002) 2.37

Compartmentalization of neutrophils in the kidney and lung following acute ischemic kidney injury. Kidney Int (2009) 2.30

Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: role of macrophages. Am J Physiol Renal Physiol (2004) 2.27

Pharmacologic treatment of acute kidney injury: why drugs haven't worked and what is on the horizon. Clin J Am Soc Nephrol (2007) 2.27

Efficacy and safety of dutasteride in patients with spinal and bulbar muscular atrophy: a randomised placebo-controlled trial. Lancet Neurol (2011) 2.27

Identification of a peripheral blood transcriptional biomarker panel associated with operational renal allograft tolerance. Proc Natl Acad Sci U S A (2007) 2.27

Role of interleukin 17 in inflammation, atherosclerosis, and vascular function in apolipoprotein e-deficient mice. Arterioscler Thromb Vasc Biol (2011) 2.27

TIPE2, a negative regulator of innate and adaptive immunity that maintains immune homeostasis. Cell (2008) 2.26

2,2-Dimethyl-2,3-dihydro-1-benzofuran-7-yl N-ethyl-carbamate. Acta Crystallogr Sect E Struct Rep Online (2009) 2.24

Renal ischemia-reperfusion injury and adenosine 2A receptor-mediated tissue protection: the role of CD4+ T cells and IFN-gamma. J Immunol (2006) 2.22

Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow-derived cells. J Clin Invest (2003) 2.22

Regulatory T cells suppress innate immunity in kidney ischemia-reperfusion injury. J Am Soc Nephrol (2009) 2.18

The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell (2012) 2.17

Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Forster resonance energy transfer imaging. Proc Natl Acad Sci U S A (2008) 2.16

Expression of tumor-associated antigens in acute myeloid leukemia: Implications for specific immunotherapeutic approaches. Blood (2006) 2.14

Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice. Biomaterials (2009) 2.13

Differences between left and right ventricular chamber geometry affect cardiac vulnerability to electric shocks. Circ Res (2005) 2.11

Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. Sci Transl Med (2011) 2.10

Increased expression of CYP17 and CYP11B1 in subclinical Cushing's syndrome due to adrenal adenomas. Int J Urol (2011) 2.07

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis. Nat Genet (2011) 2.05

Atrial fibrillation and acute myocardial infarction: antithrombotic therapy and outcomes. Am J Med (2012) 2.02

Characterization of growth and differentiation in a telomerase-immortalized human corneal epithelial cell line. Invest Ophthalmol Vis Sci (2005) 2.02

Sexually transmitted disease prevalence and characteristics of market vendors in eastern China. Sex Transm Dis (2003) 2.02

Regulation of tetrahydrobiopterin biosynthesis by shear stress. Circ Res (2007) 2.01

Dendritic cells tolerized with adenosine A₂AR agonist attenuate acute kidney injury. J Clin Invest (2012) 2.00

Baseline serum lactate dehydrogenase levels for patients treated with intensity-modulated radiotherapy for nasopharyngeal carcinoma: a predictor of poor prognosis and subsequent liver metastasis. Int J Radiat Oncol Biol Phys (2011) 1.99

Elevated levels of hypoxia-inducible microRNA-210 in pre-eclampsia: new insights into molecular mechanisms for the disease. J Cell Mol Med (2012) 1.99

Airborne trifluoroacetic acid and its fraction from the degradation of HFC-134a in Beijing, China. Environ Sci Technol (2014) 1.96