PubRank

Claes Wahlestedt

Author PubWeight™ 148.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Genome-wide analysis of mammalian promoter architecture and evolution. Nat Genet 2006 17.19
2 The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet 2009 6.02
3 Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nat Med 2008 5.62
4 Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proc Natl Acad Sci U S A 2007 4.69
5 Regulatory roles of natural antisense transcripts. Nat Rev Mol Cell Biol 2009 4.48
6 Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A 2002 4.20
7 Complex Loci in human and mouse genomes. PLoS Genet 2006 3.74
8 The reality of pervasive transcription. PLoS Biol 2011 3.41
9 Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nat Biotechnol 2012 3.07
10 RNAdb--a comprehensive mammalian noncoding RNA database. Nucleic Acids Res 2005 2.84
11 Using molecular classification to predict gains in maximal aerobic capacity following endurance exercise training in humans. J Appl Physiol (1985) 2010 2.74
12 Striatal microRNA controls cocaine intake through CREB signalling. Nature 2010 2.56
13 A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Res 2005 2.27
14 Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Res 2005 2.20
15 Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biol 2010 2.08
16 MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction. Proc Natl Acad Sci U S A 2009 2.00
17 Considerations when using the significance analysis of microarrays (SAM) algorithm. BMC Bioinformatics 2005 1.89
18 Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy. FASEB J 2005 1.85
19 A small molecule enhances RNA interference and promotes microRNA processing. Nat Biotechnol 2008 1.80
20 Amygdala-dependent fear is regulated by Oprl1 in mice and humans with PTSD. Sci Transl Med 2013 1.74
21 Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes. Genome Med 2010 1.64
22 Improved and automated prediction of effective siRNA. Biochem Biophys Res Commun 2004 1.58
23 A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. PLoS One 2008 1.57
24 MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function. Proc Natl Acad Sci U S A 2012 1.49
25 Pseudo-messenger RNA: phantoms of the transcriptome. PLoS Genet 2006 1.46
26 Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends Genet 2012 1.46
27 Single nucleotide polymorphisms in the proximal promoter region of the adiponectin (APM1) gene are associated with type 2 diabetes in Swedish caucasians. Diabetes 2004 1.41
28 MicroRNA dysregulation in psychiatric disease. Brain Res 2010 1.34
29 Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Res 2006 1.27
30 Noncoding RNAs: couplers of analog and digital information in nervous system function? Trends Neurosci 2007 1.27
31 Intronic RNAs constitute the major fraction of the non-coding RNA in mammalian cells. BMC Genomics 2012 1.26
32 RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals. Genome Biol 2006 1.21
33 Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration? FASEB J 2007 1.19
34 Expression profiling following local muscle inactivity in humans provides new perspective on diabetes-related genes. Genomics 2005 1.18
35 microRNAs in CNS disorders. Neuromolecular Med 2009 1.17
36 Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Res 2008 1.14
37 Validating siRNA using a reporter made from synthetic DNA oligonucleotides. Biochem Biophys Res Commun 2004 1.14
38 Therapeutic potential of neuropeptide Y (NPY) receptor ligands. EMBO Mol Med 2010 1.12
39 NotI subtraction and NotI-specific microarrays to detect copy number and methylation changes in whole genomes. Proc Natl Acad Sci U S A 2002 1.10
40 Small GTP-binding protein Rac is an essential mediator of vascular endothelial growth factor-induced endothelial fenestrations and vascular permeability. Circulation 2003 1.10
41 The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function. BMC Genomics 2007 1.10
42 Personalized medicine in psychiatry: problems and promises. BMC Med 2013 1.09
43 Activity-induced and developmental downregulation of the Nogo receptor. Cell Tissue Res 2003 1.07
44 Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model. Cancer Res 2004 1.07
45 Identification of functional SNPs in the 5-prime flanking sequences of human genes. BMC Genomics 2005 1.07
46 Effective small interfering RNAs and phosphorothioate antisense DNAs have different preferences for target sites in the luciferase mRNAs. Biochem Biophys Res Commun 2003 1.06
47 A new approach to genome mapping and sequencing: slalom libraries. Nucleic Acids Res 2002 1.05
48 Decreased cerebrospinal fluid neuropeptide Y (NPY) in patients with treatment refractory unipolar major depression: preliminary evidence for association with preproNPY gene polymorphism. J Psychiatr Res 2004 1.04
49 Involvement of long noncoding RNAs in diseases affecting the central nervous system. RNA Biol 2012 1.04
50 The expression signature of in vitro senescence resembles mouse but not human aging. Genome Biol 2005 1.03
51 Platelets activated during myocardial infarction release functional miRNA, which can be taken up by endothelial cells and regulate ICAM1 expression. Blood 2013 1.03
52 Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome. Hum Genet 2013 1.01
53 Selective and brain penetrant neuropeptide y y2 receptor antagonists discovered by whole-cell high-throughput screening. Mol Pharmacol 2009 0.98
54 Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease. Neurosci Lett 2009 0.96
55 hUNC93B1: a novel human gene representing a new gene family and encoding an unc-93-like protein. Gene 2002 0.96
56 Epigenetic mechanisms of gene regulation during mammalian spermatogenesis. Epigenetics 2008 0.95
57 Human neuropeptide Y signal peptide gain-of-function polymorphism is associated with increased body mass index: possible mode of function. Regul Pept 2005 0.93
58 RNA Interference with chemically modified siRNA. Curr Top Med Chem 2006 0.93
59 No induction of anti-viral responses in human cell lines HeLa and MCF-7 when transfecting with siRNA or siLNA. Biochem Biophys Res Commun 2006 0.93
60 Locked nucleic acid containing antisense oligonucleotides enhance inhibition of HIV-1 genome dimerization and inhibit virus replication. FEBS Lett 2004 0.92
61 NotI flanking sequences: a tool for gene discovery and verification of the human genome. Nucleic Acids Res 2002 0.92
62 GeneLynx mouse: integrated portal to the mouse genome. Genome Res 2003 0.92
63 Association between the nociceptin receptor gene (OPRL1) single nucleotide polymorphisms and alcohol dependence. Addict Biol 2008 0.91
64 A novel single nucleotide polymorphism of the neuropeptide Y (NPY) gene associated with alcohol dependence. Alcohol Clin Exp Res 2005 0.91
65 NPY Leu7Pro and alcohol dependence in Finnish and Swedish populations. Alcohol Clin Exp Res 2003 0.90
66 Functional comparison of single- and double-stranded siRNAs in mammalian cells. Biochem Biophys Res Commun 2004 0.90
67 mRNA accessible site tagging (MAST): a novel high throughput method for selecting effective antisense oligonucleotides. Nucleic Acids Res 2003 0.90
68 Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. Int J Alzheimers Dis 2011 0.90
69 The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. Curr Alzheimer Res 2016 0.89
70 The Emerging Role of Non-Coding RNAs in Drug Addiction. Front Genet 2012 0.89
71 A universal plasmid library encoding all permutations of small interfering RNA. Proc Natl Acad Sci U S A 2005 0.89
72 Complex HTR2C linkage disequilibrium and promoter associations with body mass index and serum leptin. Hum Genet 2005 0.89
73 Genetics of neurological disorders. Expert Rev Mol Diagn 2004 0.88
74 RNAi screen indicates widespread biological function for human natural antisense transcripts. PLoS One 2010 0.86
75 Gene characterization index: assessing the depth of gene annotation. PLoS One 2008 0.86
76 Role of Sirtuin 1 in metabolic regulation. Drug Discov Today 2010 0.85
77 Characterization of RNA interference in rat PC12 cells: requirement of GERp95. Biochem Biophys Res Commun 2004 0.85
78 Epigenetic pathways and glioblastoma treatment. Epigenetics 2013 0.85
79 Behavioural analysis of melanin-concentrating hormone in rats: evidence for orexigenic and anxiolytic properties. Regul Pept 2003 0.84
80 Adult neurogenesis: a potential tool for early diagnosis in Alzheimer's disease? J Alzheimers Dis 2010 0.83
81 Focusing on RISC assembly in mammalian cells. Biochem Biophys Res Commun 2008 0.83
82 Nonsynonymous SNPs: validation characteristics, derived allele frequency patterns, and suggestive evidence for natural selection. Hum Mutat 2006 0.82
83 Navigating genomic maps of cancer cells. Nat Biotechnol 2010 0.82
84 Transcriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs. Breast Cancer Res Treat 2014 0.80
85 Functional interactions between delta- and mu-opioid receptors in rat thermoregulation. Eur J Pharmacol 2003 0.79
86 Anti-cataleptic effects of clozapine, but not olanzapine and quetiapine, on SCH 23390- or raclopride-induced catalepsy in rats. Eur Neuropsychopharmacol 2003 0.79
87 Quantitative codon optimisation of DNA libraries encoding sub-random peptides: design and characterisation of a novel library encoding transmembrane domain peptides. Nucleic Acids Res 2002 0.78
88 Synthesis and SAR of selective small molecule neuropeptide Y Y2 receptor antagonists. Bioorg Med Chem Lett 2012 0.77
89 Vector-based siRNA delivery strategies for high-throughput screening of novel target genes. J RNAi Gene Silencing 2005 0.76
90 Analysis of 5-hydroxytryptamine 2c receptor gene promoter variants as alcohol-dependence risk factors. Alcohol Alcohol 2004 0.76
91 Oligonucleotides for upregulating gene expression. Pharm Pat Anal 2013 0.76
92 Extracellular Uridine Triphosphate and Adenosine Triphosphate Attenuate Endothelial Inflammation through miR-22-Mediated ICAM-1 Inhibition. J Vasc Res 2015 0.76
93 RNA mechanisms in CNS systems and disorders. Brain Res 2010 0.75
94 RNAi joins the "Singles Club". Mol Ther 2012 0.75
95 Exploring the foundation of genomics: a northern blot reference set for the comparative analysis of transcript profiling technologies. Comp Funct Genomics 2004 0.75
96 How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications. Brief Bioinform 2016 0.75
97 Antisense-induced Fas mRNA degradation produces site-specific stable 3'-mRNA fragment by exonuclease cleavage at the complementary sequence. Oligonucleotides 2004 0.75
98 How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications. Brief Bioinform 2017 0.75