Published in Hypertension on January 17, 2005
The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial (AVEC) | NCT00605072
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Hypertension, orthostatic hypotension, and the risk of falls in a community-dwelling elderly population: the maintenance of balance, independent living, intellect, and zest in the elderly of Boston study. J Am Geriatr Soc (2011) 1.88
Long-term blood pressure fluctuation and cerebrovascular disease in an elderly cohort. Arch Neurol (2010) 1.80
Enhanced vasoreactivity and its response to antihypertensive therapy in hypertensive elderly women. Hypertension (2006) 1.53
Current concepts in orthostatic hypotension management. Curr Hypertens Rep (2013) 1.13
Uncontrolled hypertension and increased risk for incident heart failure in older adults with hypertension: findings from a propensity-matched prospective population study. J Am Soc Hypertens (2010) 1.04
Use of total cerebral blood flow as an imaging biomarker of known cardiovascular risks. Stroke (2013) 0.95
Blood pressure and dementia - a comprehensive review. Ther Adv Neurol Disord (2009) 0.95
Cerebral flow velocities during daily activities depend on blood pressure in patients with chronic ischemic infarctions. Stroke (2009) 0.92
Effects of centrally acting ACE inhibitors on the rate of cognitive decline in dementia. BMJ Open (2013) 0.91
Cerebrovascular support for cognitive processing in hypertensive patients is altered by blood pressure treatment. Hypertension (2008) 0.90
Evaluation and treatment of orthostatic hypotension. J Am Soc Hypertens (2013) 0.89
Effects of angiotensin II on the cerebral circulation: role of oxidative stress. Front Physiol (2013) 0.88
The impact of hypertension on cerebral perfusion and cortical thickness in older adults. J Am Soc Hypertens (2014) 0.83
A 91-year-old woman with difficult-to-control hypertension: a clinical review. JAMA (2013) 0.80
Reexamining the Effect of Antihypertensive Medications on Falls in Old Age. Hypertension (2015) 0.80
A randomized controlled trial of the effects of vitamin D supplementation on arterial stiffness and aortic blood pressure in Native American women. Atherosclerosis (2015) 0.79
The association between within-visit blood pressure variability and carotid artery atherosclerosis in general population. PLoS One (2014) 0.78
Progression of Carotid Arterial Stiffness With Treatment of Hypertension Over 10 Years: The Multi-Ethnic Study of Atherosclerosis. Hypertension (2016) 0.75
Effect of antihypertensive therapy on cognitive functions of patients with hypertension. Ann Indian Acad Neurol (2010) 0.75
Isometric Exercise Training for Managing Vascular Risk Factors in Mild Cognitive Impairment and Alzheimer's Disease. Front Aging Neurosci (2017) 0.75
Cerebral small-resistance artery structure and cerebral blood flow in normotensive subjects and hypertensive patients. Neuroradiology (2014) 0.75
Lessons from a pilot and feasibility randomised trial in depression (Blood pressure Rapid Intensive Lowering And Normal Treatment for Mood and cognition in persistent depression (BRILiANT mood study)). Pilot Feasibility Stud (2015) 0.75
Intima-media thickness of carotid artery and aortic pulse wave velocity as determinants of cerebral blood flow velocity. J Hum Hypertens (2013) 0.75
Endothelial Mineralocorticoid Receptor Mediates Parenchymal Arteriole and Posterior Cerebral Artery Remodeling During Angiotensin II-Induced Hypertension. Hypertension (2017) 0.75
The resting perfusion pattern associates with functional decline in type 2 diabetes. Neurobiol Aging (2017) 0.75
Biological, clinical and population relevance of 95 loci for blood lipids. Nature (2010) 28.21
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet (2010) 23.08
Common variants at 30 loci contribute to polygenic dyslipidemia. Nat Genet (2008) 20.66
Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature (2010) 20.01
Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25
Abdominal visceral and subcutaneous adipose tissue compartments: association with metabolic risk factors in the Framingham Heart Study. Circulation (2007) 12.79
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study. Lancet (2012) 12.10
Variants in MTNR1B influence fasting glucose levels. Nat Genet (2008) 10.85
The Third Generation Cohort of the National Heart, Lung, and Blood Institute's Framingham Heart Study: design, recruitment, and initial examination. Am J Epidemiol (2007) 9.90
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet (2007) 9.80
Genotype score in addition to common risk factors for prediction of type 2 diabetes. N Engl J Med (2008) 9.68
The clinical course of advanced dementia. N Engl J Med (2009) 9.54
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution. Nat Genet (2010) 7.94
Disclosure of APOE genotype for risk of Alzheimer's disease. N Engl J Med (2009) 6.43
A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. BMC Med Genet (2007) 5.64
Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture. Nat Genet (2012) 5.48
Loss-of-function mutations in APOC3, triglycerides, and coronary disease. N Engl J Med (2014) 5.47
Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat Genet (2009) 5.32
Brief intervention for medical inpatients with unhealthy alcohol use: a randomized, controlled trial. Ann Intern Med (2007) 4.73
Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis. PLoS Genet (2009) 4.71
Homocysteine as a predictive factor for hip fracture in older persons. N Engl J Med (2004) 4.34
Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium. Nat Genet (2009) 4.28
Chronic musculoskeletal pain and the occurrence of falls in an older population. JAMA (2009) 4.18
Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Am J Hum Genet (2002) 4.07
Survival and comfort after treatment of pneumonia in advanced dementia. Arch Intern Med (2010) 3.72
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Nat Genet (2010) 3.55
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture. Nat Genet (2013) 3.25
Alcohol consumption and HIV disease progression. J Acquir Immune Defic Syndr (2007) 3.24
Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals. PLoS Genet (2012) 3.21
NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium. PLoS Genet (2009) 3.18
Risk of dementia among white and African American relatives of patients with Alzheimer disease. JAMA (2002) 3.16
Design of the Coronary ARtery DIsease Genome-Wide Replication And Meta-Analysis (CARDIoGRAM) Study: A Genome-wide association meta-analysis involving more than 22 000 cases and 60 000 controls. Circ Cardiovasc Genet (2010) 3.15
The landscape of recombination in African Americans. Nature (2011) 3.06
Genetic associations with valvular calcification and aortic stenosis. N Engl J Med (2013) 3.02
Framingham Heart Study 100K project: genome-wide associations for cardiovascular disease outcomes. BMC Med Genet (2007) 2.93
Common variants associated with plasma triglycerides and risk for coronary artery disease. Nat Genet (2013) 2.92
Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Arch Neurol (2010) 2.91
Candidate gene association resource (CARe): design, methods, and proof of concept. Circ Cardiovasc Genet (2010) 2.91
Dying with advanced dementia in the nursing home. Arch Intern Med (2004) 2.90
Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. PLoS Genet (2013) 2.83
Collaborative meta-analysis: associations of 150 candidate genes with osteoporosis and osteoporotic fracture. Ann Intern Med (2009) 2.80
FTO genotype is associated with phenotypic variability of body mass index. Nature (2012) 2.77
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. Nat Genet (2011) 2.73
CUBN is a gene locus for albuminuria. J Am Soc Nephrol (2011) 2.70
The relationship between leg power and physical performance in mobility-limited older people. J Am Geriatr Soc (2002) 2.65
Best practices and joint calling of the HumanExome BeadChip: the CHARGE Consortium. PLoS One (2013) 2.65
Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nat Genet (2013) 2.62
Value of high-density lipoprotein (HDL) subpopulations in predicting recurrent cardiovascular events in the Veterans Affairs HDL Intervention Trial. Arterioscler Thromb Vasc Biol (2005) 2.61
A 100K genome-wide association scan for diabetes and related traits in the Framingham Heart Study: replication and integration with other genome-wide datasets. Diabetes (2007) 2.60
Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies. Am J Hum Genet (2010) 2.57
Depression as a risk factor for Alzheimer disease: the MIRAGE Study. Arch Neurol (2003) 2.56
Estimating prognosis for nursing home residents with advanced dementia. JAMA (2004) 2.49
Who seeks genetic susceptibility testing for Alzheimer's disease? Findings from a multisite, randomized clinical trial. Genet Med (2004) 2.44
An integration of genome-wide association study and gene expression profiling to prioritize the discovery of novel susceptibility Loci for osteoporosis-related traits. PLoS Genet (2010) 2.43
The MOBILIZE Boston Study: design and methods of a prospective cohort study of novel risk factors for falls in an older population. BMC Geriatr (2008) 2.42
Randomized trial of a delirium abatement program for postacute skilled nursing facilities. J Am Geriatr Soc (2010) 2.38
Genomewide linkage analysis to serum creatinine, GFR, and creatinine clearance in a community-based population: the Framingham Heart Study. J Am Soc Nephrol (2004) 2.36
Chronic care management for dependence on alcohol and other drugs: the AHEAD randomized trial. JAMA (2013) 2.36
A comparison of leg power and leg strength within the InCHIANTI study: which influences mobility more? J Gerontol A Biol Sci Med Sci (2003) 2.36
Functional variant of CYP4A11 20-hydroxyeicosatetraenoic acid synthase is associated with essential hypertension. Circulation (2004) 2.35
Health behavior changes after genetic risk assessment for Alzheimer disease: The REVEAL Study. Alzheimer Dis Assoc Disord (2008) 2.30
Chemokine receptor mutant CX3CR1-M280 has impaired adhesive function and correlates with protection from cardiovascular disease in humans. J Clin Invest (2003) 2.27
Advanced dementia research in the nursing home: the CASCADE study. Alzheimer Dis Assoc Disord (2006) 2.24
Association of leukocyte telomere length with circulating biomarkers of the renin-angiotensin-aldosterone system: the Framingham Heart Study. Circulation (2008) 2.22
Association between the UGT1A1*28 allele, bilirubin levels, and coronary heart disease in the Framingham Heart Study. Circulation (2006) 2.18
Town-level characteristics and smoking policy adoption in Massachusetts: are local restaurant smoking regulations fostering disparities in health protection? Am J Public Health (2004) 2.14
Interactions of dietary whole-grain intake with fasting glucose- and insulin-related genetic loci in individuals of European descent: a meta-analysis of 14 cohort studies. Diabetes Care (2010) 2.14
Association between estrogen receptor alpha gene variation and cardiovascular disease. JAMA (2003) 2.10
Genetic risk reclassification for type 2 diabetes by age below or above 50 years using 40 type 2 diabetes risk single nucleotide polymorphisms. Diabetes Care (2010) 2.06
Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study. Clin Chem (2004) 2.05
Genetic risk assessment for adult children of people with Alzheimer's disease: the Risk Evaluation and Education for Alzheimer's Disease (REVEAL) study. J Geriatr Psychiatry Neurol (2005) 2.03
Relation of C-reactive protein to stroke, cognitive disorders, and depression in the general population: systematic review and meta-analysis. Lancet Neurol (2005) 2.01
Genome-wide association study for subclinical atherosclerosis in major arterial territories in the NHLBI's Framingham Heart Study. BMC Med Genet (2007) 2.00
High-density lipoprotein subpopulation profile and coronary heart disease prevalence in male participants of the Framingham Offspring Study. Arterioscler Thromb Vasc Biol (2004) 2.00
A genome-wide scan for loci linked to plasma levels of glucose and HbA(1c) in a community-based sample of Caucasian pedigrees: The Framingham Offspring Study. Diabetes (2002) 1.99
Office-based management of opioid dependence with buprenorphine: clinical practices and barriers. J Gen Intern Med (2008) 1.98
Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci. Am J Hum Genet (2012) 1.96
Genome-wide association meta-analysis for total serum bilirubin levels. Hum Mol Genet (2009) 1.96
Genome-wide association study for coronary artery calcification with follow-up in myocardial infarction. Circulation (2011) 1.96
Enhanced statistical tests for GWAS in admixed populations: assessment using African Americans from CARe and a Breast Cancer Consortium. PLoS Genet (2011) 1.94
Outcomes of older people admitted to postacute facilities with delirium. J Am Geriatr Soc (2005) 1.94
Screening and brief intervention for unhealthy drug use in primary care settings: randomized clinical trials are needed. J Addict Med (2010) 1.93
Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque. Nat Genet (2011) 1.92
Determinants of progression from microalbuminuria to proteinuria in patients who have type 1 diabetes and are treated with angiotensin-converting enzyme inhibitors. Clin J Am Soc Nephrol (2007) 1.92
Hypertension, orthostatic hypotension, and the risk of falls in a community-dwelling elderly population: the maintenance of balance, independent living, intellect, and zest in the elderly of Boston study. J Am Geriatr Soc (2011) 1.88
Genome-wide search for genes affecting serum uric acid levels: the Framingham Heart Study. Metabolism (2005) 1.88
Prediction of 6-month survival of nursing home residents with advanced dementia using ADEPT vs hospice eligibility guidelines. JAMA (2010) 1.87
Association between concurrent and remote blood pressure and disability in older adults. Hypertension (2007) 1.87
A genome scan for modifiers of age at onset in Huntington disease: The HD MAPS study. Am J Hum Genet (2003) 1.85
Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. PLoS Genet (2012) 1.84
Treating homeless opioid dependent patients with buprenorphine in an office-based setting. J Gen Intern Med (2007) 1.84
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet (2010) 1.83
Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans. J Clin Invest (2009) 1.83
Issues in conducting epidemiologic research among elders: lessons from the MOBILIZE Boston Study. Am J Epidemiol (2008) 1.83
A genetic risk score is associated with incident cardiovascular disease and coronary artery calcium: the Framingham Heart Study. Circ Cardiovasc Genet (2012) 1.81
Performance of random forest when SNPs are in linkage disequilibrium. BMC Bioinformatics (2009) 1.81
Heritability of age at natural menopause in the Framingham Heart Study. J Clin Endocrinol Metab (2005) 1.80
Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study. Diabetes (2008) 1.80
Geriatric syndromes in older homeless adults. J Gen Intern Med (2011) 1.79
Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease. Alzheimer Dis Assoc Disord (2003) 1.79