Published in J Immunol on February 01, 2005
NK cell development, homeostasis and function: parallels with CD8⁺ T cells. Nat Rev Immunol (2011) 3.38
Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity. J Exp Med (2007) 3.36
The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol (2009) 3.27
Death by a thousand cuts: granzyme pathways of programmed cell death. Annu Rev Immunol (2008) 2.97
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors. J Exp Med (2010) 2.87
Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue. Immunity (2010) 2.67
Antiviral CD4+ memory T cells are IL-15 dependent. J Exp Med (2007) 2.29
A novel pathway of chronic allograft rejection mediated by NK cells and alloantibody. Am J Transplant (2011) 2.16
Cutting edge: Priming of NK cells by IL-18. J Immunol (2008) 2.08
CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells. J Exp Med (2007) 1.82
IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol (2010) 1.79
Location and cellular stages of natural killer cell development. Trends Immunol (2013) 1.59
miR-150 regulates the development of NK and iNKT cells. J Exp Med (2011) 1.53
Activated T cells secrete an alternatively spliced form of common γ-chain that inhibits cytokine signaling and exacerbates inflammation. Immunity (2014) 1.51
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells. Nat Immunol (2014) 1.51
TGF-beta signaling in dendritic cells is a prerequisite for the control of autoimmune encephalomyelitis. Proc Natl Acad Sci U S A (2008) 1.48
Interleukin 21: a cytokine/cytokine receptor system that has come of age. J Leukoc Biol (2008) 1.48
Identification of the earliest natural killer cell-committed progenitor in murine bone marrow. Blood (2011) 1.45
IL-12 initiates tumor rejection via lymphoid tissue-inducer cells bearing the natural cytotoxicity receptor NKp46. Nat Immunol (2010) 1.43
The p110 delta of PI3K plays a critical role in NK cell terminal maturation and cytokine/chemokine generation. J Exp Med (2008) 1.34
Transcriptional regulation of innate lymphoid cell fate. Nat Rev Immunol (2015) 1.21
Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1. Immunity (2012) 1.18
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Homeostatic maintenance of T cells and natural killer cells. Cell Mol Life Sci (2012) 1.13
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TGF-β is responsible for NK cell immaturity during ontogeny and increased susceptibility to infection during mouse infancy. Nat Immunol (2012) 1.08
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Regulating the immune system via IL-15 transpresentation. Cytokine (2012) 1.08
Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15/IL-15Ralpha complexes. Proc Natl Acad Sci U S A (2010) 1.07
Tumor growth impedes natural-killer-cell maturation in the bone marrow. Blood (2006) 1.06
Human natural killer cell development in secondary lymphoid tissues. Semin Immunol (2014) 1.01
A review of trafficking and activation of uterine natural killer cells. Am J Reprod Immunol (2005) 1.00
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Transience in polarization of cytolytic effectors is required for efficient killing and controlled by Cdc42. Proc Natl Acad Sci U S A (2010) 0.93
Multiple hats for natural killers. Curr Opin Immunol (2010) 0.92
Deletion of PI3K-p85alpha gene impairs lineage commitment, terminal maturation, cytokine generation and cytotoxicity of NK cells. Genes Immun (2008) 0.91
The ontogeny and fate of NK cells marked by permanent DNA rearrangements. J Immunol (2008) 0.91
Exogenous IL-15 in combination with IL-15R alpha rescues natural killer cells from apoptosis induced by chronic alcohol consumption. Alcohol Clin Exp Res (2008) 0.90
Protein Kinase C-θ (PKC-θ) in Natural Killer Cell Function and Anti-Tumor Immunity. Front Immunol (2012) 0.90
Diverse roles of inhibitor of differentiation 2 in adaptive immunity. Clin Dev Immunol (2011) 0.90
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NK cells in the CD19- B220+ bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursors. Mech Ageing Dev (2009) 0.88
Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen. J Leukoc Biol (2012) 0.87
Transcription factor Runx3 regulates interleukin-15-dependent natural killer cell activation. Mol Cell Biol (2014) 0.86
PDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsiveness. J Exp Med (2015) 0.86
Development of murine hepatic NK cells during ontogeny: comparison with spleen NK cells. Clin Dev Immunol (2011) 0.85
Altered distribution of natural killer cell subsets identified by CD56, CD27 and CD70 in primary and chronic human immunodeficiency virus-1 infection. Immunology (2007) 0.85
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Gamma c cytokines condition the progressive differentiation of CD4+ T cells. Proc Natl Acad Sci U S A (2007) 0.84
The Rag2⁻Il2rb⁻Dmd⁻ mouse: a novel dystrophic and immunodeficient model to assess innovating therapeutic strategies for muscular dystrophies. Mol Ther (2013) 0.84
Epigenetic control of natural killer cell maturation by histone H2A deubiquitinase, MYSM1. Proc Natl Acad Sci U S A (2013) 0.84
IL-21: a pleiotropic cytokine with potential applications in oncology. J Immunol Res (2015) 0.83
RNA silencing and HIV: a hypothesis for the etiology of the severe combined immunodeficiency induced by the virus. Retrovirology (2008) 0.83
Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7. Int Immunol (2009) 0.83
Differential chemotactic receptor requirements for NK cell subset trafficking into bone marrow. Front Immunol (2013) 0.83
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Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors. BMC Immunol (2013) 0.82
Cytokine Concentrations in Plasma from Children with Severe and Non-Severe Community Acquired Pneumonia. PLoS One (2015) 0.80
NK cells and their ability to modulate T cells during virus infections. Crit Rev Immunol (2014) 0.80
Adoptive transfer of osteoclast-expanded natural killer cells for immunotherapy targeting cancer stem-like cells in humanized mice. Cancer Immunol Immunother (2016) 0.79
The aged nonhematopoietic environment impairs natural killer cell maturation and function. Aging Cell (2015) 0.79
A defining factor for natural killer cell development. Nat Immunol (2009) 0.79
Biopolymer encapsulated live influenza virus as a universal CD8+ T cell vaccine against influenza virus. Vaccine (2010) 0.79
NK Cell Proliferation Induced by IL-15 Transpresentation Is Negatively Regulated by Inhibitory Receptors. J Immunol (2015) 0.78
Interferon Gamma and Contact-dependent Cytotoxicity Are Each Rate Limiting for Natural Killer Cell-Mediated Antibody-dependent Chronic Rejection. Am J Transplant (2016) 0.77
Cord Blood Mononuclear Cells Have a Potential to Produce NK Cells Using IL2Rg Cytokines. Adv Pharm Bull (2016) 0.77
Uterine Natural Killer Cells: Functional Distinctions and Influence on Pregnancy in Humans and Mice. Front Immunol (2017) 0.76
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IL2RG reversion event in a common lymphoid progenitor leads to delayed diagnosis and milder phenotype. J Clin Immunol (2015) 0.75
Homeostasis of IL-15 dependent lymphocyte subsets in the liver. Cytokine (2016) 0.75
Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC. Oncotarget (2015) 0.75
STATs in NK-Cells: The Good, the Bad, and the Ugly. Front Immunol (2017) 0.75
Tentative and transient natural killer cell polarization balances the requirements for discriminatory recognition and cytolytic efficacy. Commun Integr Biol (2010) 0.75
Molecular mechanisms influencing NK cell development: implications for NK cell malignancies. Am J Blood Res (2011) 0.75
Generation of CD2(+)CD8(+) NK Cells from c-kit(+) Bone Marrow Cells in Porcine. Korean J Physiol Pharmacol (2012) 0.75
Interleukin-12 bypasses common gamma-chain signalling in emergency natural killer cell lymphopoiesis. Nat Commun (2016) 0.75
Reconstitution of multifunctional CD56(low)CD16(low) natural killer cell subset in children with acute leukemia given α/β T cell-depleted HLA-haploidentical haematopoietic stem cell transplantation. Oncoimmunology (2017) 0.75
Obestatin Increases the Regenerative Capacity of Human Myoblasts Transplanted Intramuscularly in an Immunodeficient Mouse Model. Mol Ther (2017) 0.75
Subset- and tissue-defined STAT5 thresholds control homeostasis and function of innate lymphoid cells. J Exp Med (2017) 0.75
Innate lymphoid cells--a proposal for uniform nomenclature. Nat Rev Immunol (2013) 7.94
Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Immunity (2008) 6.49
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nat Immunol (2010) 6.02
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature (2011) 4.92
Lineage relationship analysis of RORgammat+ innate lymphoid cells. Science (2010) 4.12
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells. J Exp Med (2008) 3.85
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127. Nat Immunol (2006) 3.74
IL-15 trans-presentation promotes human NK cell development and differentiation in vivo. J Exp Med (2008) 3.03
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota. Nat Immunol (2011) 3.03
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors. J Exp Med (2010) 2.87
Reprogramming of T cells to natural killer-like cells upon Bcl11b deletion. Science (2010) 2.77
Developmental pathways that generate natural-killer-cell diversity in mice and humans. Nat Rev Immunol (2007) 2.66
Humanized mice for modeling human infectious disease: challenges, progress, and outlook. Cell Host Microbe (2009) 2.58
What does it take to make a natural killer? Nat Rev Immunol (2003) 2.30
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development. Nat Immunol (2003) 2.24
IL-15 is an essential mediator of peripheral NK-cell homeostasis. Blood (2003) 2.20
GATA-3 promotes maturation, IFN-gamma production, and liver-specific homing of NK cells. Immunity (2003) 2.15
Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases. Nat Immunol (2006) 2.15
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo. J Clin Invest (2009) 2.08
Debugging how bacteria manipulate the immune response. Immunity (2007) 2.06
The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs. Nat Immunol (2005) 1.98
Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies. Aging Cell (2007) 1.98
NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases. Nat Immunol (2003) 1.89
Regulation of cytokine secretion in human CD127(+) LTi-like innate lymphoid cells by Toll-like receptor 2. Immunity (2010) 1.85
CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells. J Exp Med (2007) 1.82
IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function. Eur J Immunol (2010) 1.79
Neutrophils mediate antibody-induced antitumor effects in mice. Blood (2013) 1.66
Impaired natural killer cell phenotype and function in idiopathic and heritable pulmonary arterial hypertension. Circulation (2012) 1.59
Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth. Proc Natl Acad Sci U S A (2011) 1.59
gamma(c) cytokines provide multiple homeostatic signals to naive CD4(+) T cells. Eur J Immunol (2007) 1.55
Renaissance for mouse models of human hematopoiesis and immunobiology. Nat Immunol (2009) 1.54
IL-15 availability conditions homeostasis of peripheral natural killer T cells. Proc Natl Acad Sci U S A (2003) 1.45
The natural cytotoxicity receptor NKp46 is dispensable for IL-22-mediated innate intestinal immune defense against Citrobacter rodentium. J Immunol (2009) 1.44
Natural killer cell activation in mice and men: different triggers for similar weapons? Nat Immunol (2002) 1.44
Immature NK cells, capable of producing IL-22, are present in human uterine mucosa. J Immunol (2010) 1.41
Dicer-dependent microRNA pathway controls invariant NKT cell development. J Immunol (2009) 1.41
Unique receptor repertoire in mouse uterine NK cells. J Immunol (2008) 1.41
Maternal uterine NK cell-activating receptor KIR2DS1 enhances placentation. J Clin Invest (2013) 1.36
Gata3 drives development of RORγt+ group 3 innate lymphoid cells. J Exp Med (2014) 1.36
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo. Proc Natl Acad Sci U S A (2011) 1.35
A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation. J Immunol (2003) 1.34
An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation. J Immunol (2008) 1.34
Are major histocompatibility complex molecules involved in the survival of naive CD4+ T cells? J Exp Med (2003) 1.34
Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells. Proc Natl Acad Sci U S A (2013) 1.34
Intravital imaging reveals distinct dynamics for natural killer and CD8(+) T cells during tumor regression. Immunity (2010) 1.32
Distinguishing features of developing natural killer cells. Curr Opin Immunol (2005) 1.31
Phospholipase C-gamma2 is essential for NK cell cytotoxicity and innate immunity to malignant and virally infected cells. Blood (2005) 1.31
Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice. PLoS One (2010) 1.29
Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases. Nat Immunol (2002) 1.29
Pneumococcal polysaccharide vaccination for adults: new perspectives for Europe. Expert Rev Vaccines (2011) 1.29
Characterization of the thymic IL-7 niche in vivo. Proc Natl Acad Sci U S A (2009) 1.27
Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1. J Virol (2004) 1.24
Uterine NK cells: active regulators at the maternal-fetal interface. J Clin Invest (2014) 1.23
Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity. J Immunol (2010) 1.22
IL-7 enhances thymic human T cell development in "human immune system" Rag2-/-IL-2Rgammac-/- mice without affecting peripheral T cell homeostasis. J Immunol (2009) 1.18
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice. Am J Pathol (2009) 1.18
The p110delta catalytic isoform of PI3K is a key player in NK-cell development and cytokine secretion. Blood (2007) 1.18
Roles for T and NK cells in the innate immune response to Shigella flexneri. J Immunol (2005) 1.17
Role of an intact splenic microarchitecture in early lymphocytic choriomeningitis virus production. J Virol (2002) 1.14
IL-2 is required for the activation of memory CD8+ T cells via antigen cross-presentation. J Immunol (2006) 1.13
Interleukin-15-dependent NKp46+ innate lymphoid cells control intestinal inflammation by recruiting inflammatory monocytes. Immunity (2012) 1.12
Thymocytes may persist and differentiate without any input from bone marrow progenitors. J Exp Med (2012) 1.12
DBA-lectin reactivity defines mouse uterine natural killer cell subsets with biased gene expression. Biol Reprod (2012) 1.11
Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment. Proc Natl Acad Sci U S A (2004) 1.11
Enhancement of myogenic and muscle repair capacities of human adipose-derived stem cells with forced expression of MyoD. Mol Ther (2009) 1.11
IL-15 transpresentation promotes both human T-cell reconstitution and T-cell-dependent antibody responses in vivo. Proc Natl Acad Sci U S A (2011) 1.10
Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site. J Cell Biol (2002) 1.10
Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver. Blood (2002) 1.09
Invariant V alpha 14+ NKT cells participate in the early response to enteric Listeria monocytogenes infection. J Immunol (2005) 1.08
GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice. Blood (2013) 1.08
Analysis of uterine natural killer cells in mice. Methods Mol Biol (2010) 1.08
Competition within the early B-cell compartment conditions B-cell reconstitution after hematopoietic stem cell transplantation in nonirradiated recipients. Blood (2006) 1.06
Isolation of a highly myogenic CD34-negative subset of human skeletal muscle cells free of adipogenic potential. Stem Cells (2010) 1.06
Dynamic behavior of NK cells during activation in lymph nodes. Blood (2009) 1.04
Cmv4, a new locus linked to the NK cell gene complex, controls innate resistance to cytomegalovirus in wild-derived mice. J Immunol (2006) 1.04
Repopulation of athymic mouse liver by cryopreserved early human fetal hepatoblasts. Hum Gene Ther (2004) 1.03
Proinflammatory macrophages enhance the regenerative capacity of human myoblasts by modifying their kinetics of proliferation and differentiation. Mol Ther (2012) 1.01
c-Jun NH2-terminal kinase/c-Jun signaling promotes survival and metastasis of B lymphocytes transformed by Theileria. Cancer Res (2006) 1.01
Cutting edge: Thymic NK cells develop independently from T cell precursors. J Immunol (2010) 1.01
p110gamma and p110delta isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease. Proc Natl Acad Sci U S A (2009) 1.00
NK cell responses to Plasmodium infection and control of intrahepatic parasite development. J Immunol (2006) 1.00
Developmental programming of natural killer and innate lymphoid cells. Curr Opin Immunol (2013) 0.98
Lymphocytes support oval cell-dependent liver regeneration. J Immunol (2008) 0.98
Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo. J Immunol (2013) 0.95
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Gamma(c) deficiency precludes CD8+ T cell memory despite formation of potent T cell effectors. Proc Natl Acad Sci U S A (2010) 0.95