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1
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Behavioural assessment of drug reinforcement and addictive features in rodents: an overview.
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Addict Biol
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2006
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3.94
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2
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Genome-wide association study of alcohol dependence.
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Arch Gen Psychiatry
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2009
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3.08
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3
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Withdrawal phenomena and dependence syndrome after the consumption of "spice gold".
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Dtsch Arztebl Int
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2009
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2.94
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4
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Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc.
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Nat Neurosci
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2009
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2.50
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5
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Cocaine sensitization and reward are under the influence of circadian genes and rhythm.
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Proc Natl Acad Sci U S A
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2002
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2.40
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6
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Glutamate receptors on dopamine neurons control the persistence of cocaine seeking.
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Neuron
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2008
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2.37
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7
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Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration.
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Neuropsychopharmacology
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2004
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2.16
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8
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Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption.
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Proc Natl Acad Sci U S A
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2011
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2.01
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9
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Adolescent impulsivity phenotypes characterized by distinct brain networks.
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Nat Neurosci
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2012
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1.98
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10
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Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood.
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Curr Biol
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2008
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1.97
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11
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Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS.
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J Neurosci
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2003
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1.94
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12
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Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors.
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Science
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2002
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1.93
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13
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Chronic intake of fermented floral nectar by wild treeshrews.
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Proc Natl Acad Sci U S A
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2008
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1.89
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14
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mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior.
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Neuropsychopharmacology
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2004
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1.83
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15
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Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians.
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Hepatology
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2010
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1.65
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16
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Risk taking and the adolescent reward system: a potential common link to substance abuse.
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Am J Psychiatry
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2011
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1.56
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17
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Ambiguous-cue interpretation is biased under stress- and depression-like states in rats.
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Neuropsychopharmacology
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2009
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1.54
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18
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Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior.
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Arch Gen Psychiatry
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2008
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1.39
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19
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Influence of age at drinking onset on long-term ethanol self-administration with deprivation and stress phases.
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Alcohol Clin Exp Res
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2005
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1.36
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20
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The glucocorticoid receptor as a potential target to reduce cocaine abuse.
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J Neurosci
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2003
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1.34
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21
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Acamprosate: recent findings and future research directions.
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Alcohol Clin Exp Res
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2008
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1.33
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22
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Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse.
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J Neurosci
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2006
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1.24
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23
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Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence.
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J Neurosci
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2013
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1.22
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24
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Neurocircuitry for modeling drug effects.
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Addict Biol
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2012
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1.22
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25
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A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake.
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Alcohol Clin Exp Res
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2003
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1.21
|
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26
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Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study.
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Arch Gen Psychiatry
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2010
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1.21
|
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27
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Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats.
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Biol Psychiatry
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2011
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1.18
|
|
28
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Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.
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Am J Psychiatry
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2011
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1.15
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29
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The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect.
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Neuropharmacology
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2005
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1.15
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30
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Compulsive alcohol drinking in rodents.
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Addict Biol
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2009
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1.15
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31
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cDNA microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise.
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Physiol Genomics
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2005
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1.13
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32
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The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat.
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Neuropsychopharmacology
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2005
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1.12
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33
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The dopamine D3 receptor plays an essential role in alcohol-seeking and relapse.
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FASEB J
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2006
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1.12
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34
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Reduced sensitivity to reward in CB1 knockout mice.
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Psychopharmacology (Berl)
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2004
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1.11
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|
35
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Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats.
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Pharmacol Biochem Behav
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2006
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1.10
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36
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Glutamatergic targets for new alcohol medications.
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Psychopharmacology (Berl)
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2013
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1.10
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37
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RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release.
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Proc Natl Acad Sci U S A
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2012
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1.06
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38
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Rats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning.
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Behav Brain Res
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2004
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1.05
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39
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D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in rats.
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Alcohol Alcohol
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2008
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1.04
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40
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Circadian regulation of central ethanol sensitivity by the mPer2 gene.
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Addict Biol
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2009
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1.03
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41
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Determinants of early alcohol use in healthy adolescents: the differential contribution of neuroimaging and psychological factors.
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Neuropsychopharmacology
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2011
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1.03
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42
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Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1(Brdm1) mutant mice.
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Psychopharmacology (Berl)
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2006
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1.01
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43
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Social and structural housing conditions influence the development of a depressive-like phenotype in the learned helplessness paradigm in male mice.
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Behav Brain Res
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2005
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1.00
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44
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Circadian expression of clock- and tumor suppressor genes in human oral mucosa.
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Cell Physiol Biochem
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2010
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0.99
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45
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Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats.
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Biol Psychiatry
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2010
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0.99
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46
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Fractalkine-upregulated milk-fat globule EGF factor-8 protein in cultured rat microglia.
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J Neuroimmunol
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2005
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0.99
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47
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Stress triggers anhedonia in rats bred for learned helplessness.
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Behav Brain Res
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2010
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0.97
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48
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Clock genes running amok. Clock genes and their role in drug addiction and depression.
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EMBO Rep
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2007
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0.96
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49
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Importance of NO/cGMP signalling via cGMP-dependent protein kinase II for controlling emotionality and neurobehavioural effects of alcohol.
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Eur J Neurosci
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2004
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0.96
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50
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Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories.
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Psychopharmacology (Berl)
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2009
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0.96
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51
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Cocaine-induced dopamine overflow within the nucleus accumbens measured by in vivo microdialysis: a meta-analysis.
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Synapse
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2008
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0.95
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52
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Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats.
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Front Behav Neurosci
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2010
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0.95
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53
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Candidate genes for alcohol dependence: animal studies.
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Alcohol Clin Exp Res
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2003
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0.94
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54
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Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine.
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Proc Natl Acad Sci U S A
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2008
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0.93
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55
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Inhibition of the casein-kinase-1-ε/δ/ prevents relapse-like alcohol drinking.
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Neuropsychopharmacology
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2012
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0.93
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56
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Loss of the serum response factor in the dopamine system leads to hyperactivity.
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FASEB J
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2010
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0.92
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57
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Differential involvement of the opioid receptor antagonist naloxone in motivational and hedonic aspects of reward.
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Behav Brain Res
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2009
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0.92
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58
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Alcohol self-administration in two rat lines selectively bred for extremes in anxiety-related behavior.
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Neuropsychopharmacology
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2002
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0.92
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59
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Analysis of genetic variations of protein tyrosine kinase fyn and their association with alcohol dependence in two independent cohorts.
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Biol Psychiatry
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2003
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0.92
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60
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The mGluR2/3 agonist LY379268 induced anti-reinstatement effects in rats exhibiting addiction-like behavior.
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Neuropsychopharmacology
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2013
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0.91
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61
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Structural synaptic elements are differentially regulated in superior temporal cortex of schizophrenia patients.
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Eur Arch Psychiatry Clin Neurosci
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2012
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0.91
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62
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Effects of morphine withdrawal on micro-opioid receptor-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate autoradiography in rat brain.
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Eur J Pharmacol
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2002
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0.91
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63
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The effects of drugs of abuse on clock genes.
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Drug News Perspect
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2008
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0.91
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64
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Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking.
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Neuropsychopharmacology
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2011
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0.90
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65
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Incentive learning underlying cocaine-seeking requires mGluR5 receptors located on dopamine D1 receptor-expressing neurons.
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J Neurosci
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2010
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0.90
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66
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The effects of lamotrigine on alcohol seeking and relapse.
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Neuropharmacology
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2007
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0.90
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67
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The impact of acetylcholinesterase inhibitors on the extracellular acetylcholine concentrations in the adult rat brain: a meta-analysis.
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Synapse
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2012
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0.89
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68
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Cluster and meta-analyses on factors influencing stress-induced alcohol drinking and relapse in rodents.
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Addict Biol
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2014
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0.89
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69
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Ethanol induces expression of the glutamate transporters EAAT1 and EAAT2 in organotypic cortical slice cultures.
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Alcohol Clin Exp Res
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2004
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0.88
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70
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The use of a novel drinkometer system for assessing pharmacological treatment effects on ethanol consumption in rats.
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Alcohol Clin Exp Res
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2012
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0.87
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71
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Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST.
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Neuropharmacology
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2012
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0.86
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72
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Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice.
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BMC Neurosci
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2007
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0.86
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73
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Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study.
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World J Biol Psychiatry
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2010
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0.85
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74
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Appetitive odor-cue conditioning attenuates the acoustic startle response in rats.
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Behav Brain Res
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2007
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0.85
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75
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A novel elevated plus-maze procedure to avoid the one-trial tolerance problem.
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Front Behav Neurosci
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2011
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0.85
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76
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Decreased reward sensitivity in rats from the Fischer344 strain compared to Wistar rats is paralleled by differences in endocannabinoid signaling.
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PLoS One
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2012
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0.84
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77
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Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels.
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Int J Neuropsychopharmacol
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2011
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0.84
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78
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Expression of N-methyl-d-aspartate (NMDA) receptor subunits and splice variants in an animal model of long-term voluntary alcohol self-administration.
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Drug Alcohol Depend
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2008
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0.84
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79
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Per1(Brdm1) mice self-administer cocaine and reinstate cocaine-seeking behaviour following extinction.
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Behav Pharmacol
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2011
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0.83
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80
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Central metabolite changes and activation of microglia after peripheral interleukin-2 challenge.
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Brain Behav Immun
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2011
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81
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Perinatal exposure to alcohol disturbs spatial learning and glutamate transmission-related gene expression in the adult hippocampus.
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Eur J Neurosci
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2011
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0.82
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82
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Deletion of Go2alpha abolishes cocaine-induced behavioral sensitization by disturbing the striatal dopamine system.
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FASEB J
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2008
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0.81
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83
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Incubation of cocaine seeking following brief cocaine experience in mice is enhanced by mGluR1 blockade.
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J Neurosci
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2014
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0.81
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84
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Etomidate and propofol-hyposensitive GABAA receptor beta3(N265M) mice show little changes in acute alcohol sensitivity but enhanced tolerance and withdrawal.
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Neurosci Lett
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2007
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0.81
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85
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Oleoylethanolamide dose-dependently attenuates cocaine-induced behaviours through a PPARα receptor-independent mechanism.
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Addict Biol
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2012
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86
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Role of Fyn tyrosine kinase in ethanol consumption by mice.
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Alcohol Clin Exp Res
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2003
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87
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Sensorimotor gating, working and social memory deficits in mice with reduced expression of the vesicular glutamate transporter VGLUT1.
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Behav Brain Res
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2011
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88
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Measuring alcohol consumption in man--it is time for a change.
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Addiction
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2006
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Development of morphine-induced tolerance and withdrawal: involvement of the clock gene mPer2.
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Eur Neuropsychopharmacol
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0.79
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Publication trends in addiction research.
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Addict Biol
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2011
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Voluntary alcohol intake in two rat lines selectively bred for learned helpless and non-helpless behavior.
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Psychopharmacology (Berl)
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2004
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0.78
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92
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Time-dependent effects of striatal interleukin-2 on open field behaviour in rats.
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J Neuroimmunol
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93
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Ethanol induces GAD67 and VGAT in slice cultures of newborn rat cerebral cortex.
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Neuroreport
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2005
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94
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Chronic intermittent ethanol exposure in mice leads to an up-regulation of CRH/CRHR1 signaling.
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Alcohol Clin Exp Res
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2015
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95
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Perinatal exposure to alcohol reduces the expression of complexins I and II.
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Neurotoxicol Teratol
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96
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A functional Tph2 C1473G polymorphism causes an anxiety phenotype via compensatory changes in the serotonergic system.
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Neuropsychopharmacology
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2012
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97
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Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.
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Nicotine Tob Res
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2014
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98
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Global ethanol-induced enhancements of monoaminergic neurotransmission: a meta-analysis study.
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Alcohol Clin Exp Res
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2013
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99
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The ClockΔ19 mutation in mice fails to alter the primary and secondary reinforcing properties of nicotine.
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Drug Alcohol Depend
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2013
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100
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Quantum modeling of common sense.
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Behav Brain Sci
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2013
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101
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The effects of xenon and nitrous oxide gases on alcohol relapse.
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Alcohol Clin Exp Res
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2013
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102
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Amphetamine regulates NR2B expression in Go2α knockout mice and thereby sustains behavioral sensitization.
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J Neurochem
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103
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Transcriptional changes in insulin- and lipid metabolism-related genes in the hippocampus of olfactory bulbectomized mice.
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J Neurosci Res
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2008
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104
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Augmented stress-induced alcohol drinking and withdrawal in mice lacking functional natriuretic peptide-A receptors.
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Alcohol Alcohol
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[The medical treatment of attention deficit hyperactivity disorder (ADHD) with amphetamines in children and adolescents].
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Z Kinder Jugendpsychiatr Psychother
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106
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Strain-specific responses of inbred mice to ethanol following food shortage.
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Addict Biol
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2004
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107
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A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption.
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Mamm Genome
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2008
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108
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Challenges to medications development in treating alcohol dependence: an international perspective.
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Alcohol Alcohol
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2004
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109
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Science meets public.
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Addict Biol
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2006
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0.75
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[One drink, one drunk--controlled drinking by alcoholics? 3-year-outcome after intensive outpatient treatment].
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Psychother Psychosom Med Psychol
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2007
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111
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Behavioral neurobiology of alcohol addiction. Preface.
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Curr Top Behav Neurosci
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2013
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[For and against: controlled drinking as useful and necessary treatment alternative].
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Psychiatr Prax
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2005
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