Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking.

PubWeight™: 1.15‹?› | Rank: Top 10%

🔗 View Article (PMID 21828288)

Published in Am J Psychiatry on August 09, 2011

Authors

Li Dong1, Ainhoa Bilbao, Manfred Laucht, Richard Henriksson, Tatjana Yakovleva, Monika Ridinger, Sylvane Desrivieres, Toni-Kim Clarke, Anbarasu Lourdusamy, Michael N Smolka, Sven Cichon, Dorothea Blomeyer, Jens Treutlein, Stephanie Perreau-Lenz, Stephanie Witt, Fernando Leonardi-Essmann, Norbert Wodarz, Peter Zill, Michael Soyka, Urs Albrecht, Marcella Rietschel, Mark Lathrop, Georgy Bakalkin, Rainer Spanagel, Gunter Schumann

Author Affiliations

1: Medical Research Council Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King’s College London, UK.

Articles citing this

The influence of gene-environment interactions on the development of alcoholism and drug dependence. Curr Psychiatry Rep (2012) 1.13

Stress and VTA synapses: implications for addiction and depression. Eur J Neurosci (2014) 0.99

Circadian genes Period 1 and Period 2 in the nucleus accumbens regulate anxiety-related behavior. Eur J Neurosci (2012) 0.93

Inhibition of the casein-kinase-1-ε/δ/ prevents relapse-like alcohol drinking. Neuropsychopharmacology (2012) 0.93

Social rank, chronic ethanol self-administration, and diurnal pituitary-adrenal activity in cynomolgus monkeys. Psychopharmacology (Berl) (2012) 0.91

Biological contributions to addictions in adolescents and adults: prevention, treatment, and policy implications. J Adolesc Health (2013) 0.91

Association of PER2 genotype and stressful life events with alcohol drinking in young adults. PLoS One (2013) 0.88

Circadian rhythms and addiction: mechanistic insights and future directions. Behav Neurosci (2014) 0.87

Selective breeding for ethanol-related traits alters circadian phenotype. Alcohol (2013) 0.86

Diurnal pituitary-adrenal activity during schedule-induced polydipsia of water and ethanol in cynomolgus monkeys (Macaca fascicularis). Psychopharmacology (Berl) (2013) 0.85

The circadian Per1 and Per2 genes influence alcohol intake, reinforcement, and blood alcohol levels. Behav Brain Res (2013) 0.85

Diversity of human clock genotypes and consequences. Prog Mol Biol Transl Sci (2013) 0.83

Cognitive dysfunction, elevated anxiety, and reduced cocaine response in circadian clock-deficient cryptochrome knockout mice. Front Behav Neurosci (2013) 0.83

Molecular mechanisms underlying alcohol-drinking behaviours. Nat Rev Neurosci (2016) 0.83

CREB activity in dopamine D1 receptor expressing neurons regulates cocaine-induced behavioral effects. Front Behav Neurosci (2014) 0.82

Chronobiology of alcohol: studies in C57BL/6J and DBA/2J inbred mice. Physiol Behav (2013) 0.82

Stress-induced changes in the expression of the clock protein PERIOD1 in the rat limbic forebrain and hypothalamus: role of stress type, time of day, and predictability. PLoS One (2014) 0.82

Genetics and epigenetics of circadian rhythms and their potential roles in neuropsychiatric disorders. Neurosci Bull (2015) 0.79

Integration of the circadian and stress systems: influence of neuropeptides and implications for alcohol consumption. J Neural Transm (Vienna) (2012) 0.79

Minutes, days and years: molecular interactions among different scales of biological timing. Philos Trans R Soc Lond B Biol Sci (2014) 0.79

Assessing ethanol's actions in the suprachiasmatic circadian clock using in vivo and in vitro approaches. Alcohol (2014) 0.78

Circadian rhythms and risk for substance use disorders in adolescence. Curr Opin Psychiatry (2014) 0.78

Circadian clock period inversely correlates with illness severity in cells from patients with alcohol use disorders. Alcohol Clin Exp Res (2013) 0.78

Episodic memories and their relevance for psychoactive drug use and addiction. Front Behav Neurosci (2013) 0.78

Genes and Alcohol Consumption: Studies with Mutant Mice. Int Rev Neurobiol (2016) 0.78

Circadian genes, the stress axis, and alcoholism. Alcohol Res (2012) 0.77

Clock genes × stress × reward interactions in alcohol and substance use disorders. Alcohol (2015) 0.77

Glucocorticoids and Stress-Induced Changes in the Expression of PERIOD1 in the Rat Forebrain. PLoS One (2015) 0.77

The clock gene Period1 regulates innate routine behaviour in mice. Proc Biol Sci (2014) 0.76

Chronic shifts in the length and phase of the light cycle increase intermittent alcohol drinking in C57BL/6J mice. Front Behav Neurosci (2015) 0.76

Nuclear envelope regulates the circadian clock. Nucleus (2015) 0.75

Polymorphisms of genes in neurotransmitter systems were associated with alcohol use disorders in a Tibetan population. PLoS One (2013) 0.75

PER1 rs3027172 Genotype Interacts with Early Life Stress to Predict Problematic Alcohol Use, but Not Reward-Related Ventral Striatum Activity. Front Psychol (2016) 0.75

Integrated Genome-wide association and hypothalamus eQTL studies indicate a link between the circadian rhythm-related gene PER1 and coping behavior. Sci Rep (2015) 0.75

Bidirectional relationship between alcohol intake and sensitivity to social defeat: association with Tacr1 and Avp expression. Addict Biol (2017) 0.75

mPer1 promotes morphine-induced locomotor sensitization and conditioned place preference via histone deacetylase activity. Psychopharmacology (Berl) (2017) 0.75

Articles by these authors

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet (2008) 30.20

International network of cancer genome projects. Nature (2010) 20.35

Large recurrent microdeletions associated with schizophrenia. Nature (2008) 20.25

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature (2012) 16.13

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25. Nature (2008) 16.10

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet (2009) 14.86

Drugs as instruments: a new framework for non-addictive psychoactive drug use. Behav Brain Sci (2011) 14.12

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. Nat Genet (2011) 13.25

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk. Nature (2011) 13.25

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature (2011) 13.23

Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nat Genet (2008) 10.52

Common variants conferring risk of schizophrenia. Nature (2009) 10.37

The orphan nuclear receptor REV-ERBalpha controls circadian transcription within the positive limb of the mammalian circadian oscillator. Cell (2002) 9.92

Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA (2010) 9.52

Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet (2011) 9.23

Genetic variants associated with Lp(a) lipoprotein level and coronary disease. N Engl J Med (2009) 8.73

Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4. PLoS Genet (2007) 8.63

Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet (2013) 8.02

Genome-wide association study identifies five susceptibility loci for glioma. Nat Genet (2009) 7.62

Mapping complex disease traits with global gene expression. Nat Rev Genet (2009) 7.44

The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annu Rev Physiol (2010) 6.63

A mega-analysis of genome-wide association studies for major depressive disorder. Mol Psychiatry (2012) 6.34

Microduplications of 16p11.2 are associated with schizophrenia. Nat Genet (2009) 6.13

Lung cancer susceptibility locus at 5p15.33. Nat Genet (2008) 5.99

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma. Am J Hum Genet (2009) 5.62

City living and urban upbringing affect neural social stress processing in humans. Nature (2011) 5.46

Single nucleotide polymorphisms in TNFSF15 confer susceptibility to Crohn's disease. Hum Mol Genet (2005) 5.35

A genome-wide association study of alcohol dependence. Proc Natl Acad Sci U S A (2010) 4.94

Disruption of the neurexin 1 gene is associated with schizophrenia. Hum Mol Genet (2008) 4.78

Genomewide association studies: history, rationale, and prospects for psychiatric disorders. Am J Psychiatry (2009) 4.74

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 4.62

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15. Nat Genet (2007) 4.61

Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis. Nat Genet (2009) 4.38

Common variants at 10 genomic loci influence hemoglobin A₁(C) levels via glycemic and nonglycemic pathways. Diabetes (2010) 4.07

Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict Biol (2006) 3.94

Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet (2004) 3.91

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91

Effect of 17q21 variants and smoking exposure in early-onset asthma. N Engl J Med (2008) 3.90

The European dimension for the mouse genome mutagenesis program. Nat Genet (2004) 3.84

Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet (2009) 3.82

Identification of common variants associated with human hippocampal and intracranial volumes. Nat Genet (2012) 3.73

Investigation of the fine structure of European populations with applications to disease association studies. Eur J Hum Genet (2008) 3.65

The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption. Nat Med (2004) 3.63

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24. Nat Genet (2009) 3.58

Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter. Nat Neurosci (2004) 3.56

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma. Nature (2011) 3.53

Genetic structure of Europeans: a view from the North-East. PLoS One (2009) 3.46

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure. Nat Genet (2011) 3.40

Combined analysis from eleven linkage studies of bipolar disorder provides strong evidence of susceptibility loci on chromosomes 6q and 8q. Am J Hum Genet (2005) 3.24

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease. Nat Genet (2010) 3.22

Genome-wide association analysis identifies three new breast cancer susceptibility loci. Nat Genet (2012) 3.20

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma. Nat Genet (2011) 3.18

Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis. Nat Genet (2013) 3.17

The gene encoding adipose triglyceride lipase (PNPLA2) is mutated in neutral lipid storage disease with myopathy. Nat Genet (2006) 3.17

Family-based designs for genome-wide association studies. Nat Rev Genet (2011) 3.12

Intergenic variants of HBS1L-MYB are responsible for a major quantitative trait locus on chromosome 6q23 influencing fetal hemoglobin levels in adults. Proc Natl Acad Sci U S A (2007) 3.10

High frequencies of de novo CNVs in bipolar disorder and schizophrenia. Neuron (2011) 3.08

Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08

Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study. J Natl Cancer Inst (2011) 3.05

Acamprosate for alcohol dependence. Cochrane Database Syst Rev (2010) 3.03

Genome scan meta-analysis of schizophrenia and bipolar disorder, part III: Bipolar disorder. Am J Hum Genet (2003) 3.02

Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3. Nat Genet (2010) 2.96

Withdrawal phenomena and dependence syndrome after the consumption of "spice gold". Dtsch Arztebl Int (2009) 2.94

Genome-wide association study identifies two susceptibility loci for nonsyndromic cleft lip with or without cleft palate. Nat Genet (2009) 2.93

Neural mechanisms of a genome-wide supported psychosis variant. Science (2009) 2.88