Published in Neuropsychopharmacology on June 01, 2005
Toward a model of drug relapse: an assessment of the validity of the reinstatement procedure. Psychopharmacology (Berl) (2006) 4.23
Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol (2007) 3.06
Neuropharmacology of alcohol addiction. Br J Pharmacol (2008) 2.65
The reinstatement model of drug relapse: recent neurobiological findings, emerging research topics, and translational research. Psychopharmacology (Berl) (2013) 2.01
Identifying the neural circuitry of alcohol craving and relapse vulnerability. Addict Biol (2008) 1.72
Drug abstinence: exploring animal models and behavioral treatment strategies. Psychopharmacology (Berl) (2014) 1.52
Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor. Curr Opin Investig Drugs (2010) 1.49
Acamprosate produces its anti-relapse effects via calcium. Neuropsychopharmacology (2013) 1.35
Development of pharmacotherapies for drug addiction: a Rosetta stone approach. Nat Rev Drug Discov (2009) 1.30
Targeting the glutamatergic system to treat major depressive disorder: rationale and progress to date. Drugs (2012) 1.17
Acamprosate and naltrexone treatment effects on ethanol and sucrose seeking and intake in ethanol-dependent and nondependent rats. Psychopharmacology (Berl) (2009) 1.13
Association of single nucleotide polymorphisms in a glutamate receptor gene (GRM8) with theta power of event-related oscillations and alcohol dependence. Am J Med Genet B Neuropsychiatr Genet (2009) 1.12
Long-Evans rats acquire operant self-administration of 20% ethanol without sucrose fading. Neuropsychopharmacology (2010) 1.10
Relapse to drug seeking following prolonged abstinence: the role of environmental stimuli. Drug Discov Today Dis Models (2008) 1.10
Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes. Brain Res (2008) 1.01
The Potent Effect of Environmental Context on Relapse to Alcohol-Seeking After Extinction. Open Addict J (2010) 1.00
Effect of fenfluramine on reinstatement of food seeking in female and male rats: implications for the predictive validity of the reinstatement model. Psychopharmacology (Berl) (2011) 0.98
Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories. Psychopharmacology (Berl) (2009) 0.96
Influence of reinforcement schedule on ethanol consumption patterns in non-food restricted male C57BL/6J mice. Alcohol (2007) 0.94
Critical thoughts on current rodent models for evaluating potential treatments of alcohol addiction and withdrawal. Br J Pharmacol (2011) 0.94
The effects of acamprosate on alcohol-cue reactivity and alcohol priming in dependent patients: a randomized controlled trial. Psychopharmacology (Berl) (2009) 0.87
Role of cues and contexts on drug-seeking behaviour. Br J Pharmacol (2014) 0.87
Acamprosate: a prototypic neuromodulator in the treatment of alcohol dependence. CNS Neurol Disord Drug Targets (2010) 0.86
Treatment of alcohol dependence in patients with co-morbid major depressive disorder--predictors for the outcomes with memantine and escitalopram medication. Subst Abuse Treat Prev Policy (2008) 0.85
Role of a hippocampal SRC-family kinase-mediated glutamatergic mechanism in drug context-induced cocaine seeking. Neuropsychopharmacology (2013) 0.84
Metabolic shift of the kynurenine pathway impairs alcohol and cocaine seeking and relapse. Psychopharmacology (Berl) (2016) 0.80
Medications development for the treatment of alcohol use disorder: insights into the predictive value of animal and human laboratory models. Addict Biol (2016) 0.80
Acamprosate for treatment of alcohol dependence: mechanisms, efficacy, and clinical utility. Ther Clin Risk Manag (2012) 0.80
Alternative splicing of AMPA subunits in prefrontal cortical fields of cynomolgus monkeys following chronic ethanol self-administration. Front Psychiatry (2012) 0.79
Translating Alcohol Research: Opportunities and Challenges. Alcohol Res (2015) 0.76
Event-Related Oscillations in Alcoholism Research: A Review. J Addict Res Ther (2012) 0.76
The Calpain Inhibitor A-705253 Attenuates Alcohol-Seeking and Relapse with Low Side-Effect Profile. Neuropsychopharmacology (2015) 0.76
The development of acamprosate as a treatment against alcohol relapse. Expert Opin Drug Discov (2014) 0.76
Acamprosate: a new tool in the battle against alcohol dependence. Neuropsychiatr Dis Treat (2006) 0.76
Role of Hypothalamic-Pituitary-Adrenal axis and corticotropin-releasing factor stress system on cue-induced relapse to alcohol seeking. Eur J Pharmacol (2016) 0.75
Oral Conditioned Cues Can Enhance or Inhibit Ethanol (EtOH)-Seeking and EtOH-Relapse Drinking by Alcohol-Preferring (P) Rats. Alcohol Clin Exp Res (2016) 0.75
Nicotine-induced enhancement of Pavlovian alcohol-seeking behavior in rats. Psychopharmacology (Berl) (2016) 0.75
Review. Neural mechanisms underlying the vulnerability to develop compulsive drug-seeking habits and addiction. Philos Trans R Soc Lond B Biol Sci (2008) 4.85
Behavioural assessment of drug reinforcement and addictive features in rodents: an overview. Addict Biol (2006) 3.94
Genome-wide association study of alcohol dependence. Arch Gen Psychiatry (2009) 3.08
Withdrawal phenomena and dependence syndrome after the consumption of "spice gold". Dtsch Arztebl Int (2009) 2.94
Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. Nat Neurosci (2009) 2.50
Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proc Natl Acad Sci U S A (2002) 2.40
Memantine: a NMDA receptor antagonist that improves memory by restoration of homeostasis in the glutamatergic system--too little activation is bad, too much is even worse. Neuropharmacology (2007) 2.39
Glutamate receptors on dopamine neurons control the persistence of cocaine seeking. Neuron (2008) 2.37
Neurobehavioral mechanisms of impulsivity: fronto-striatal systems and functional neurochemistry. Pharmacol Biochem Behav (2007) 2.19
Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration. Neuropsychopharmacology (2004) 2.16
Genome-wide association and genetic functional studies identify autism susceptibility candidate 2 gene (AUTS2) in the regulation of alcohol consumption. Proc Natl Acad Sci U S A (2011) 2.01
Adolescent impulsivity phenotypes characterized by distinct brain networks. Nat Neurosci (2012) 1.98
Regulation of monoamine oxidase A by circadian-clock components implies clock influence on mood. Curr Biol (2008) 1.97
Impaired long-term memory and NR2A-type NMDA receptor-dependent synaptic plasticity in mice lacking c-Fos in the CNS. J Neurosci (2003) 1.94
Enhanced and delayed stress-induced alcohol drinking in mice lacking functional CRH1 receptors. Science (2002) 1.93
Chronic intake of fermented floral nectar by wild treeshrews. Proc Natl Acad Sci U S A (2008) 1.89
mGluR5 antagonist MPEP reduces ethanol-seeking and relapse behavior. Neuropsychopharmacology (2004) 1.83
Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians. Hepatology (2010) 1.65
Risk taking and the adolescent reward system: a potential common link to substance abuse. Am J Psychiatry (2011) 1.56
Ambiguous-cue interpretation is biased under stress- and depression-like states in rats. Neuropsychopharmacology (2009) 1.54
Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism. Addict Biol (2006) 1.47
Systematic analysis of glutamatergic neurotransmission genes in alcohol dependence and adolescent risky drinking behavior. Arch Gen Psychiatry (2008) 1.39
Influence of age at drinking onset on long-term ethanol self-administration with deprivation and stress phases. Alcohol Clin Exp Res (2005) 1.36
The glucocorticoid receptor as a potential target to reduce cocaine abuse. J Neurosci (2003) 1.34
Metabotropic glutamate receptor (mGluR5) antagonist MPEP attenuated cue- and schedule-induced reinstatement of nicotine self-administration behavior in rats. Neuropharmacology (2005) 1.34
Acamprosate: recent findings and future research directions. Alcohol Clin Exp Res (2008) 1.33
Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats. Psychopharmacology (Berl) (2003) 1.31
The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotropin-releasing factor and for its reversal by nociceptin/orphanin FQ. J Neurosci (2003) 1.29
Modulation of L-DOPA-induced abnormal involuntary movements by clinically tested compounds: further validation of the rat dyskinesia model. Behav Brain Res (2007) 1.28
Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats. Eur J Neurosci (2005) 1.25
Involvement of the AMPA receptor GluR-C subunit in alcohol-seeking behavior and relapse. J Neurosci (2006) 1.24
Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence. J Neurosci (2013) 1.22
Modulation of high impulsivity and attentional performance in rats by selective direct and indirect dopaminergic and noradrenergic receptor agonists. Psychopharmacology (Berl) (2011) 1.22
Neurocircuitry for modeling drug effects. Addict Biol (2012) 1.22
A comparative study on alcohol-preferring rat lines: effects of deprivation and stress phases on voluntary alcohol intake. Alcohol Clin Exp Res (2003) 1.21
Effect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcohol-dependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry (2010) 1.21
Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system. Biol Psychiatry (2006) 1.20
Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats. Biol Psychiatry (2011) 1.18
Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking. Biol Psychiatry (2011) 1.17
Effects of the circadian rhythm gene period 1 (per1) on psychosocial stress-induced alcohol drinking. Am J Psychiatry (2011) 1.15
Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol. Addict Biol (2007) 1.15
Compulsive alcohol drinking in rodents. Addict Biol (2009) 1.15
The role of the NMDA receptor in alcohol relapse: a pharmacological mapping study using the alcohol deprivation effect. Neuropharmacology (2005) 1.15
mGlu1 receptor blockade attenuates cue- and nicotine-induced reinstatement of extinguished nicotine self-administration behavior in rats. Neuropharmacology (2006) 1.15
Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats. Psychopharmacology (Berl) (2005) 1.15
Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat. Biol Psychiatry (2008) 1.14
cDNA microarray analysis reveals novel candidate genes expressed in human peripheral blood following exhaustive exercise. Physiol Genomics (2005) 1.13
The dopamine D3 receptor plays an essential role in alcohol-seeking and relapse. FASEB J (2006) 1.12
Antagonism of metabotropic glutamate receptor type 5 attenuates l-DOPA-induced dyskinesia and its molecular and neurochemical correlates in a rat model of Parkinson's disease. J Neurochem (2007) 1.12
Reduced sensitivity to reward in CB1 knockout mice. Psychopharmacology (Berl) (2004) 1.11
Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin. Brain Res (2009) 1.11
Glutamatergic targets for new alcohol medications. Psychopharmacology (Berl) (2013) 1.10
Influence of age at drinking onset on the alcohol deprivation effect and stress-induced drinking in female rats. Pharmacol Biochem Behav (2006) 1.10
Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system. Proc Natl Acad Sci U S A (2010) 1.10
Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vivo studies. J Pharmacol Exp Ther (2007) 1.09
Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. Neuron (2012) 1.06
RASGRF2 regulates alcohol-induced reinforcement by influencing mesolimbic dopamine neuron activity and dopamine release. Proc Natl Acad Sci U S A (2012) 1.06
Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats. Neuropharmacology (2002) 1.06
Rats with congenital learned helplessness respond less to sucrose but show no deficits in activity or learning. Behav Brain Res (2004) 1.05
A mGluR5 antagonist under clinical development improves L-DOPA-induced dyskinesia in parkinsonian rats and monkeys. Neurobiol Dis (2010) 1.04
Potential role of N-methyl-D-aspartate receptors as executors of neurodegeneration resulting from diverse insults: focus on memantine. Behav Pharmacol (2006) 1.04
Persistent increase of alcohol-seeking evoked by neuropeptide S: an effect mediated by the hypothalamic hypocretin system. Neuropsychopharmacology (2009) 1.04
D-cycloserine facilitates extinction of conditioned alcohol-seeking behaviour in rats. Alcohol Alcohol (2008) 1.04
Circadian regulation of central ethanol sensitivity by the mPer2 gene. Addict Biol (2009) 1.03
Determinants of early alcohol use in healthy adolescents: the differential contribution of neuroimaging and psychological factors. Neuropsychopharmacology (2011) 1.03
Effects of NAAG peptidase inhibitor 2-PMPA in model chronic pain - relation to brain concentration. Neuropharmacology (2006) 1.03
Effects of group I metabotropic glutamate receptor antagonists on the behavioral sensitization to motor effects of cocaine in rats. Psychopharmacology (Berl) (2006) 1.02
Ethanol self-administration and reinstatement of ethanol-seeking behavior in Per1(Brdm1) mutant mice. Psychopharmacology (Berl) (2006) 1.01
Anxiolytic-like effects of mGlu1 and mGlu5 receptor antagonists in rats. Eur J Pharmacol (2005) 1.01
Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. Psychopharmacology (Berl) (2008) 1.01
Effects of group I metabotropic glutamate receptors blockade in experimental models of Parkinson's disease. Brain Res Bull (2006) 1.00
Enhancement of long-term spatial memory in adult rats by the noncompetitive NMDA receptor antagonists, memantine and neramexane. Pharmacol Biochem Behav (2006) 1.00
Social and structural housing conditions influence the development of a depressive-like phenotype in the learned helplessness paradigm in male mice. Behav Brain Res (2005) 1.00
Effects of a metabotropic glutamate receptor group II agonist LY354740 in animal models of positive schizophrenia symptoms and cognition. Behav Pharmacol (2009) 1.00
Antagonism at NMDA receptors, but not β-adrenergic receptors, disrupts the reconsolidation of pavlovian conditioned approach and instrumental transfer for ethanol-associated conditioned stimuli. Psychopharmacology (Berl) (2011) 1.00
Glycine transporter-1 blockade leads to persistently reduced relapse-like alcohol drinking in rats. Biol Psychiatry (2010) 0.99
Circadian expression of clock- and tumor suppressor genes in human oral mucosa. Cell Physiol Biochem (2010) 0.99
Neuroprotective activity of selective mGlu1 and mGlu5 antagonists in vitro and in vivo. Eur J Pharmacol (2006) 0.99
Fractalkine-upregulated milk-fat globule EGF factor-8 protein in cultured rat microglia. J Neuroimmunol (2005) 0.99
Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats. Pharmacol Biochem Behav (2011) 0.98
Effects of nicotinic and NMDA receptor channel blockers on intravenous cocaine and nicotine self-administration in mice. Eur Neuropsychopharmacol (2005) 0.98
Promising medications for cocaine dependence treatment. Recent Pat CNS Drug Discov (2011) 0.98
The anandamide transport inhibitor AM404 reduces ethanol self-administration. Eur J Neurosci (2007) 0.98
Pharmacological modulation of glutamate transmission in a rat model of L-DOPA-induced dyskinesia: effects on motor behavior and striatal nuclear signaling. J Pharmacol Exp Ther (2009) 0.98
The nociceptin/orphanin FQ/NOP receptor system as a target for treatment of alcohol abuse: a review of recent work in alcohol-preferring rats. Physiol Behav (2003) 0.97
Stress triggers anhedonia in rats bred for learned helplessness. Behav Brain Res (2010) 0.97
Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68. Peptides (2010) 0.97
Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease. Neurotox Res (2013) 0.96
Clock genes running amok. Clock genes and their role in drug addiction and depression. EMBO Rep (2007) 0.96
Importance of NO/cGMP signalling via cGMP-dependent protein kinase II for controlling emotionality and neurobehavioural effects of alcohol. Eur J Neurosci (2004) 0.96
Comparison of the mGlu(5) receptor positive allosteric modulator ADX47273 and the mGlu(2/3) receptor agonist LY354740 in tests for antipsychotic-like activity. Eur J Pharmacol (2009) 0.96
Activation of brain NOP receptors attenuates acute and protracted alcohol withdrawal symptoms in the rat. Alcohol Clin Exp Res (2011) 0.96
Cue-induced alcohol-seeking behaviour is reduced by disrupting the reconsolidation of alcohol-related memories. Psychopharmacology (Berl) (2009) 0.96
Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol (2009) 0.96
Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology. Recent Dev Alcohol (2003) 0.95
Reward sensitivity for a palatable food reward peaks during pubertal developmental in rats. Front Behav Neurosci (2010) 0.95