PubRank

Arthur M Mercurio

Author PubWeight™ 70.45‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 ERbeta impedes prostate cancer EMT by destabilizing HIF-1alpha and inhibiting VEGF-mediated snail nuclear localization: implications for Gleason grading. Cancer Cell 2010 3.25
2 Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription: implications for the epithelial-mesenchymal transition. J Cell Biol 2005 2.88
3 VEGF targets the tumour cell. Nat Rev Cancer 2013 2.71
4 Transcriptional activation of integrin beta6 during the epithelial-mesenchymal transition defines a novel prognostic indicator of aggressive colon carcinoma. J Clin Invest 2005 2.61
5 IAP regulation of metastasis. Cancer Cell 2010 2.47
6 Vascular endothelial growth factor promotes breast carcinoma invasion in an autocrine manner by regulating the chemokine receptor CXCR4. Cancer Res 2002 2.20
7 Tumor necrosis factor-alpha stimulates the epithelial-to-mesenchymal transition of human colonic organoids. Mol Biol Cell 2003 2.11
8 The epithelial-mesenchymal transition (EMT) and colorectal cancer progression. Cancer Biol Ther 2005 2.10
9 Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells. Cancer Res 2003 1.95
10 Functional analysis of the contribution of RhoA and RhoC GTPases to invasive breast carcinoma. Cancer Res 2004 1.83
11 Integrin (alpha 6 beta 4) regulation of eIF-4E activity and VEGF translation: a survival mechanism for carcinoma cells. J Cell Biol 2002 1.66
12 Hypoxia stimulates carcinoma invasion by stabilizing microtubules and promoting the Rab11 trafficking of the alpha6beta4 integrin. Cancer Res 2005 1.61
13 Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression. Cancer Metastasis Rev 2005 1.58
14 Proteases, extracellular matrix, and cancer: a workshop of the path B study section. Am J Pathol 2004 1.52
15 Transcriptional regulation of VEGF-A by the unfolded protein response pathway. PLoS One 2010 1.52
16 Altered localization of p120 catenin during epithelial to mesenchymal transition of colon carcinoma is prognostic for aggressive disease. Cancer Res 2005 1.49
17 miR-10b targets Tiam1: implications for Rac activation and carcinoma migration. J Biol Chem 2010 1.41
18 Analysis of integrin beta4 expression in human breast cancer: association with basal-like tumors and prognostic significance. Clin Cancer Res 2008 1.40
19 Flt-1-dependent survival characterizes the epithelial-mesenchymal transition of colonic organoids. Curr Biol 2003 1.36
20 GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation. EMBO Mol Med 2013 1.33
21 Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes. Mol Cell Biol 2004 1.31
22 Regulation of beta 4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition. J Cell Sci 2009 1.25
23 A role for ADAM12 in breast tumor progression and stromal cell apoptosis. Cancer Res 2005 1.24
24 ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function. J Cell Sci 2003 1.21
25 The epithelial-mesenchymal transition of colon carcinoma involves expression of IL-8 and CXCR-1-mediated chemotaxis. Exp Cell Res 2004 1.16
26 ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA. J Biol Chem 2002 1.16
27 Role of JNK in mammary gland development and breast cancer. Cancer Res 2011 1.14
28 The alpha6beta4 integrin maintains the survival of human breast carcinoma cells in vivo. Cancer Res 2005 1.14
29 Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2. J Biol Chem 2008 1.14
30 IMP3, a new biomarker to predict progression of cervical intraepithelial neoplasia into invasive cancer. Am J Surg Pathol 2011 1.13
31 The Met receptor and alpha 6 beta 4 integrin can function independently to promote carcinoma invasion. J Biol Chem 2004 1.06
32 VEGF/neuropilin-2 regulation of Bmi-1 and consequent repression of IGF-IR define a novel mechanism of aggressive prostate cancer. Cancer Discov 2012 1.06
33 The alpha6beta4 integrin can regulate ErbB-3 expression: implications for alpha6beta4 signaling and function. Cancer Res 2007 1.04
34 Intrinsic signaling functions of the beta4 integrin intracellular domain. J Biol Chem 2007 1.00
35 Use of RNA interference to inhibit integrin (alpha6beta4)-mediated invasion and migration of breast carcinoma cells. Clin Exp Metastasis 2003 0.99
36 ADAM12 produced by tumor cells rather than stromal cells accelerates breast tumor progression. Mol Cancer Res 2011 0.99
37 Neuropilin-2 regulates α6β1 integrin in the formation of focal adhesions and signaling. J Cell Sci 2012 0.98
38 Contributions of the alpha6 integrins to breast carcinoma survival and progression. Mol Cells 2004 0.97
39 Paternal RLIM/Rnf12 is a survival factor for milk-producing alveolar cells. Cell 2012 0.97
40 Insulin receptor substrate-2 regulates aerobic glycolysis in mouse mammary tumor cells via glucose transporter 1. J Biol Chem 2008 0.95
41 Epithelial-mesenchymal transition and colorectal cancer: gaining insights into tumor progression using LIM 1863 cells. Cells Tissues Organs 2007 0.93
42 Estrogen receptor β sustains epithelial differentiation by regulating prolyl hydroxylase 2 transcription. Proc Natl Acad Sci U S A 2013 0.93
43 Hypoxia-induced vascular endothelial growth factor transcription and protection from apoptosis are dependent on alpha6beta1 integrin in breast carcinoma cells. Cancer Res 2004 0.91
44 Integrin β4 regulates SPARC protein to promote invasion. J Biol Chem 2012 0.91
45 IMP3 protein promotes chemoresistance in breast cancer cells by regulating breast cancer resistance protein (ABCG2) expression. J Biol Chem 2013 0.91
46 Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB. J Biol Chem 2005 0.90
47 Id2 complexes with the SNAG domain of Snai1 inhibiting Snai1-mediated repression of integrin β4. Mol Cell Biol 2013 0.89
48 Enhancing integrin function by VEGF/neuropilin signaling: implications for tumor biology. Cell Adh Migr 2012 0.88
49 Ras stimulation of E2F activity and a consequent E2F regulation of integrin alpha6beta4 promote the invasion of breast carcinoma cells. Cancer Res 2006 0.85
50 Effects of β4 integrin expression on microRNA patterns in breast cancer. Biol Open 2012 0.85
51 Neuropilin-2 promotes branching morphogenesis in the mouse mammary gland. Development 2011 0.84
52 Expression of the beta 4 integrin subunit induces monocytic differentiation of 32D/v-Abl cells. Blood 2002 0.76