Published in J Biol Chem on January 24, 2005
Signaling mechanisms underlying Slit2-induced collapse of Xenopus retinal growth cones. Neuron (2006) 2.45
Functions of cofilin in cell locomotion and invasion. Nat Rev Mol Cell Biol (2013) 1.95
Calcium signaling and amyloid toxicity in Alzheimer disease. J Biol Chem (2010) 1.78
BMP gradients steer nerve growth cones by a balancing act of LIM kinase and Slingshot phosphatase on ADF/cofilin. J Cell Biol (2007) 1.66
Kainate seizures cause acute dendritic injury and actin depolymerization in vivo. J Neurosci (2007) 1.61
Reactive oxygen species regulate a slingshot-cofilin activation pathway. Mol Biol Cell (2009) 1.56
Molecular mechanisms of dendrite stability. Nat Rev Neurosci (2013) 1.44
Synaptopodin Is a Coincidence Detector of Tyrosine versus Serine/Threonine Phosphorylation for the Modulation of Rho Protein Crosstalk in Podocytes. J Am Soc Nephrol (2016) 1.40
A conserved docking site modulates substrate affinity for calcineurin, signaling output, and in vivo function. Mol Cell (2007) 1.38
SynGAP regulates steady-state and activity-dependent phosphorylation of cofilin. J Neurosci (2008) 1.35
Cofilin under control of β-arrestin-2 in NMDA-dependent dendritic spine plasticity, long-term depression (LTD), and learning. Proc Natl Acad Sci U S A (2012) 1.22
The role of actin filament dynamics in the myogenic response of cerebral resistance arteries. J Cereb Blood Flow Metab (2012) 1.21
ADF/Cofilin-actin rods in neurodegenerative diseases. Curr Alzheimer Res (2010) 1.18
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin. EMBO J (2007) 1.14
Accumulation of NFAT mediates IL-2 expression in memory, but not naïve, CD4+ T cells. Proc Natl Acad Sci U S A (2007) 1.12
Mutant huntingtin impairs immune cell migration in Huntington disease. J Clin Invest (2012) 1.11
Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus. Neuroscience (2008) 1.08
A cellular mechanism for dendritic spine loss in the pilocarpine model of status epilepticus. Epilepsia (2008) 1.07
Actin depolymerization factor/cofilin activation regulates actin polymerization and tension development in canine tracheal smooth muscle. J Biol Chem (2008) 1.06
Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex. J Neurosci (2009) 1.02
Distinct dendritic spine and nuclear phases of calcineurin activation after exposure to amyloid-β revealed by a novel fluorescence resonance energy transfer assay. J Neurosci (2012) 0.99
Accelerators, Brakes, and Gears of Actin Dynamics in Dendritic Spines. Open Neurosci J (2009) 0.99
TRPC1 channels regulate directionality of migrating cells. Pflugers Arch (2008) 0.99
Regulation of AMPA receptor channels and synaptic plasticity by cofilin phosphatase Slingshot in cortical neurons. J Physiol (2010) 0.96
Incorporation of cofilin into rods depends on disulfide intermolecular bonds: implications for actin regulation and neurodegenerative disease. J Neurosci (2012) 0.93
Swiprosin-1 modulates actin dynamics by regulating the F-actin accessibility to cofilin. Cell Mol Life Sci (2013) 0.93
Ca2+/calmodulin-dependent protein kinase IV-mediated LIM kinase activation is critical for calcium signal-induced neurite outgrowth. J Biol Chem (2009) 0.92
Expression of rotavirus NSP4 alters the actin network organization through the actin remodeling protein cofilin. J Virol (2007) 0.90
Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim. Proc Natl Acad Sci U S A (2015) 0.87
The Interface between Cytoskeletal Aberrations and Mitochondrial Dysfunction in Alzheimer's Disease and Related Disorders. Exp Neurobiol (2011) 0.86
Epidermal growth factor receptor-PI3K signaling controls cofilin activity to facilitate herpes simplex virus 1 entry into neuronal cells. MBio (2014) 0.86
Mechanisms of dendritic spine remodeling in a rat model of traumatic brain injury. J Neurotrauma (2011) 0.86
LIM Kinase, a Newly Identified Regulator of Presynaptic Remodeling by Rod Photoreceptors After Injury. Invest Ophthalmol Vis Sci (2015) 0.85
Slingshot isoform-specific regulation of cofilin-mediated vascular smooth muscle cell migration and neointima formation. Arterioscler Thromb Vasc Biol (2011) 0.84
Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons. Mol Biol Cell (2012) 0.84
Novel PKCα-mediated phosphorylation site(s) on cofilin and their potential role in terminating histamine release. Mol Biol Cell (2012) 0.83
The calcium/calcineurin pathway promotes hemidesmosome stability through inhibition of β4 integrin phosphorylation. J Biol Chem (2012) 0.82
Detection of structural and metabolic changes in traumatically injured hippocampus by quantitative differential proteomics. J Neurotrauma (2012) 0.82
Cellular control of connective tissue matrix tension. J Cell Biochem (2013) 0.82
Slit-2 repels the migration of olfactory ensheathing cells by triggering Ca2+-dependent cofilin activation and RhoA inhibition. J Cell Sci (2011) 0.82
Gene expression analyses of primary melanomas reveal CTHRC1 as an important player in melanoma progression. Oncotarget (2016) 0.81
DSCR1 is required for both axonal growth cone extension and steering. J Cell Biol (2016) 0.81
Mechanosensitive channels in striated muscle and the cardiovascular system: not quite a stretch anymore. J Cardiovasc Pharmacol (2009) 0.81
Potential role of drebrin a, an f-actin binding protein, in reactive synaptic plasticity after pilocarpine-induced seizures: functional implications in epilepsy. Int J Cell Biol (2012) 0.80
Actin dynamics and cofilin-actin rods in alzheimer disease. Cytoskeleton (Hoboken) (2016) 0.80
Calcineurin regulation of cytoskeleton organization: a new paradigm to analyse the effects of calcineurin inhibitors on the kidney. J Cell Mol Med (2012) 0.80
EphA signaling promotes actin-based dendritic spine remodeling through slingshot phosphatase. J Biol Chem (2012) 0.80
Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity. Neuropharmacology (2015) 0.79
Exploration of molecular pathways mediating electric field-directed Schwann cell migration by RNA-seq. J Cell Physiol (2015) 0.79
Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation. J Biol Chem (2014) 0.78
Rapid hippocampal network adaptation to recurring synchronous activity--a role for calcineurin. Eur J Neurosci (2013) 0.77
Jak3 enables chemokine-dependent actin cytoskeleton reorganization by regulating cofilin and Rac/Rhoa GTPases activation. PLoS One (2014) 0.77
Calcium influx through CRAC channels controls actin organization and dynamics at the immune synapse. Elife (2016) 0.77
Slingshot-Cofilin activation mediates mitochondrial and synaptic dysfunction via Aβ ligation to β1-integrin conformers. Cell Death Differ (2015) 0.76
Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system. Biochem J (2016) 0.76
Protein kinase D promotes plasticity-induced F-actin stabilization in dendritic spines and regulates memory formation. J Cell Biol (2015) 0.76
RanBP9 at the intersection between cofilin and Aβ pathologies: rescue of neurodegenerative changes by RanBP9 reduction. Cell Death Dis (2015) 0.76
Peptide regulation of cofilin activity in the CNS: A novel therapeutic approach for treatment of multiple neurological disorders. Pharmacol Ther (2017) 0.75
The Impact of Electrographic Seizures on Developing Hippocampal Dendrites Is Calcineurin Dependent. eNeuro (2017) 0.75
Cofilin Inhibition Restores Neuronal Cell Death in Oxygen-Glucose Deprivation Model of Ischemia. Mol Neurobiol (2014) 0.75
Cofilin Mediates LPS-Induced Microglial Cell Activation and Associated Neurotoxicity Through Activation of NF-κB and JAK-STAT Pathway. Mol Neurobiol (2017) 0.75
Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner. PLoS One (2017) 0.75
Homocysteine induces hypophosphorylation of intermediate filaments and reorganization of actin cytoskeleton in C6 glioma cells. Cell Mol Neurobiol (2009) 0.75
Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo. Neuron (2003) 4.47
Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell (2002) 3.83
Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot. Nat Cell Biol (2009) 2.31
NFAT functions as a working memory of Ca2+ signals in decoding Ca2+ oscillation. EMBO J (2003) 2.24
A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. J Cell Biol (2004) 2.14
Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J Cell Biol (2005) 2.05
Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. J Cell Biol (2007) 1.93
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci U S A (2010) 1.64
Histone deacetylase 7 associates with hypoxia-inducible factor 1alpha and increases transcriptional activity. J Biol Chem (2004) 1.60
Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin. J Neurosci (2003) 1.58
MAPKAPK-2-mediated LIM-kinase activation is critical for VEGF-induced actin remodeling and cell migration. EMBO J (2006) 1.57
Stromal cell-derived factor 1alpha activates LIM kinase 1 and induces cofilin phosphorylation for T-cell chemotaxis. Mol Cell Biol (2002) 1.49
Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture. J Biol Chem (2010) 1.43
Differential activities, subcellular distribution and tissue expression patterns of three members of Slingshot family phosphatases that dephosphorylate cofilin. Genes Cells (2003) 1.42
LIM kinase and slingshot are critical for neurite extension. J Biol Chem (2007) 1.40
Cell cycle-associated changes in Slingshot phosphatase activity and roles in cytokinesis in animal cells. J Biol Chem (2003) 1.39
Phosphoinositide 3-kinase-mediated activation of cofilin phosphatase Slingshot and its role for insulin-induced membrane protrusion. J Biol Chem (2003) 1.34
MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes. Curr Biol (2009) 1.28
The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes. J Biol Chem (2007) 1.27
LIM kinase-mediated cofilin phosphorylation during mitosis is required for precise spindle positioning. J Biol Chem (2007) 1.26
Alteration of phosphatidylinositol 3-kinase cascade in the multilobulated nuclear formation of adult T cell leukemia/lymphoma (ATLL). Proc Natl Acad Sci U S A (2005) 1.25
Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension. J Cell Biol (2011) 1.17
Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells. Circ Res (2007) 1.17
Cancer susceptibility and embryonic lethality in Mob1a/1b double-mutant mice. J Clin Invest (2012) 1.16
Mitosis-specific activation of LIM motif-containing protein kinase and roles of cofilin phosphorylation and dephosphorylation in mitosis. J Biol Chem (2002) 1.15
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin. EMBO J (2007) 1.14
Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1. Eur J Biochem (2002) 1.13
Actin reorganization and morphological changes in human neutrophils stimulated by TNF, GM-CSF, and G-CSF: the role of MAP kinases. Am J Physiol Cell Physiol (2003) 1.12
Protein kinase D regulates cofilin activity through p21-activated kinase 4. J Biol Chem (2011) 1.10
Activation of the CKI-CDK-Rb-E2F pathway in full genome hepatitis C virus-expressing cells. J Biol Chem (2004) 1.07
Hypoxia and angiogenesis: regulation of hypoxia-inducible factors via novel binding factors. Exp Mol Med (2009) 1.07
NDR2-mediated Rabin8 phosphorylation is crucial for ciliogenesis by switching binding specificity from phosphatidylserine to Sec15. EMBO J (2013) 1.06
Differential neuroprotection by cyclosporin A and FK506 following ischemia corresponds with differing abilities to inhibit calcineurin and the mitochondrial permeability transition. Neurobiol Dis (2002) 1.06
Negative regulation of yeast Eps15-like Arp2/3 complex activator, Pan1p, by the Hip1R-related protein, Sla2p, during endocytosis. Mol Biol Cell (2006) 1.03
F- and G-actin homeostasis regulates mechanosensitive actin nucleation by formins. Nat Cell Biol (2013) 1.03
Molecular dissection of the mechanisms of substrate recognition and F-actin-mediated activation of cofilin-phosphatase Slingshot-1. J Biol Chem (2008) 1.02
β-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6. Sci Signal (2013) 1.02
Up-regulation of glyceraldehyde-3-phosphate dehydrogenase gene expression by HIF-1 activity depending on Sp1 in hypoxic breast cancer cells. Arch Biochem Biophys (2011) 1.01
Mammalian tumor suppressor Int6 specifically targets hypoxia inducible factor 2 alpha for degradation by hypoxia- and pVHL-independent regulation. J Biol Chem (2007) 1.01
Synaptic scaffolding molecule alpha is a scaffold to mediate N-methyl-D-aspartate receptor-dependent RhoA activation in dendrites. Mol Cell Biol (2007) 1.01
Cofilin-mediated F-actin severing is regulated by the Rap GTPase and controls the cytoskeletal dynamics that drive lymphocyte spreading and BCR microcluster formation. J Immunol (2011) 1.00
Galpha12/13-mediated production of reactive oxygen species is critical for angiotensin receptor-induced NFAT activation in cardiac fibroblasts. J Biol Chem (2005) 1.00
Identification of multiple actin-binding sites in cofilin-phosphatase Slingshot-1L. FEBS Lett (2006) 1.00
Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase. J Biol Chem (2008) 0.98
Visualization of cofilin-actin and Ras-Raf interactions by bimolecular fluorescence complementation assays using a new pair of split Venus fragments. Biotechniques (2012) 0.96
Cell adhesion-dependent cofilin serine 3 phosphorylation by the integrin-linked kinase.c-Src complex. J Biol Chem (2008) 0.96
Involvement of p114-RhoGEF and Lfc in Wnt-3a- and dishevelled-induced RhoA activation and neurite retraction in N1E-115 mouse neuroblastoma cells. Mol Biol Cell (2010) 0.95
Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase. Biochem J (2005) 0.94
Requirements for recruitment of a G protein-coupled receptor to clathrin-coated pits in budding yeast. Mol Biol Cell (2009) 0.94
Critical roles of actin-interacting protein 1 in cytokinesis and chemotactic migration of mammalian cells. Biochem J (2008) 0.93
Ca2+/calmodulin-dependent protein kinase IV-mediated LIM kinase activation is critical for calcium signal-induced neurite outgrowth. J Biol Chem (2009) 0.92
Updated values for molecular diagnosis for highly pathogenic avian influenza virus. Viruses (2012) 0.92
The temporal profile of genomic responses and protein synthesis in ischemic tolerance of the rat brain induced by repeated hyperbaric oxygen. Brain Res (2006) 0.92
CAMP (C13orf8, ZNF828) is a novel regulator of kinetochore-microtubule attachment. EMBO J (2010) 0.92
Chemical chaperones reduce aggregate formation and cell death caused by the truncated Machado-Joseph disease gene product with an expanded polyglutamine stretch. Neurobiol Dis (2002) 0.91
AILIM/ICOS signaling induces T-cell migration/polarization of memory/effector T-cells. Int Immunol (2004) 0.91
LIM-kinase is critical for the mesenchymal-to-amoeboid cell morphological transition in 3D matrices. Biochem Biophys Res Commun (2010) 0.90
Broad-spectrum detection of H5 subtype influenza A viruses with a new fluorescent immunochromatography system. PLoS One (2013) 0.90
Tesk1 interacts with Spry2 to abrogate its inhibition of ERK phosphorylation downstream of receptor tyrosine kinase signaling. J Biol Chem (2007) 0.89
Calcineurin inhibits Na+/Ca2+ exchange in phenylephrine-treated hypertrophic cardiomyocytes. J Biol Chem (2004) 0.89
Expression of phosphorylated Ser70 of Bcl-2 correlates with malignancy in human colorectal neoplasms. Clin Cancer Res (2005) 0.88
p63RhoGEF-mediated formation of a single polarized lamellipodium is required for chemotactic migration in breast carcinoma cells. FEBS Lett (2013) 0.88
Furry promotes acetylation of microtubules in the mitotic spindle by inhibition of SIRT2 tubulin deacetylase. J Cell Sci (2013) 0.88
LIM kinase has a dual role in regulating lamellipodium extension by decelerating the rate of actin retrograde flow and the rate of actin polymerization. J Biol Chem (2011) 0.88
Int6/eIF3e silencing promotes functional blood vessel outgrowth and enhances wound healing by upregulating hypoxia-induced factor 2alpha expression. Circulation (2010) 0.87
Rapid typing of influenza viruses using super high-speed quantitative real-time PCR. J Virol Methods (2011) 0.87
Cytochalasin D acts as an inhibitor of the actin-cofilin interaction. Biochem Biophys Res Commun (2012) 0.87
CaMKIIβ-mediated LIM-kinase activation plays a crucial role in BDNF-induced neuritogenesis. Genes Cells (2013) 0.86
Damnacanthal, an effective inhibitor of LIM-kinase, inhibits cell migration and invasion. Mol Biol Cell (2014) 0.86
Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane. Eur J Immunol (2004) 0.86
LIM kinase 1 modulates opsonized zymosan-triggered activation of macrophage-like U937 cells. Possible involvement of phosphorylation of cofilin and reorganization of actin cytoskeleton. J Biol Chem (2001) 0.85
Caspase-mediated cleavage and activation of LIM-kinase 1 and its role in apoptotic membrane blebbing. Genes Cells (2004) 0.85
AILIM/ICOS-mediated elongation of activated T cells is regulated by both the PI3-kinase/Akt and Rho family cascade. Int Immunol (2006) 0.84
Binding to Cep164, but not EB1, is essential for centriolar localization of TTBK2 and its function in ciliogenesis. Genes Cells (2014) 0.84
Furry protein promotes aurora A-mediated Polo-like kinase 1 activation. J Biol Chem (2012) 0.83
Probing the molecular mechanisms of neuronal degeneration: importance of mitochondrial dysfunction and calcineurin activation. J Anesth (2008) 0.83
Novel PKCα-mediated phosphorylation site(s) on cofilin and their potential role in terminating histamine release. Mol Biol Cell (2012) 0.83
CD29 integrin- and LIMK1/cofilin-mediated actin reorganization regulates the migration of haematopoietic progenitor cells underneath bone marrow stromal cells. Genes Cells (2004) 0.83
Cyclophilin D-sensitive mitochondrial permeability transition in adult human brain and liver mitochondria. J Neurotrauma (2011) 0.82
Live-cell imaging of G-actin dynamics using sequential FDAP. Bioarchitecture (2011) 0.82
Coactosin accelerates cell dynamism by promoting actin polymerization. Dev Biol (2013) 0.81
Actin filaments-stabilizing and -bundling activities of cofilin-phosphatase Slingshot-1. Genes Cells (2007) 0.81
Bcl-2 phosphorylation in the BH4 domain precedes caspase-3 activation and cell death after neonatal cerebral hypoxic-ischemic injury. Neurobiol Dis (2005) 0.81
Development of a highly sensitive immuno-PCR assay for the measurement of α-galactosidase A protein levels in serum and plasma. PLoS One (2013) 0.80
NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappaB signaling pathway. Biochem Biophys Res Commun (2009) 0.79
Modification of a fiber protein in an adenovirus vector improves in vitro gene transfer efficiency to the mouse microglial cell line. Neurosci Lett (2002) 0.79
[Angiogenesis and metastasis of carcinoma]. Clin Calcium (2006) 0.79
Int6/eIF3e silenced HIF2α stabilization enhances migration and tube formation of HUVECs via IL-6 and IL-8 signaling. Cytokine (2013) 0.79
Int6 silencing causes induction of angiogenic factors in neuronal cells via accumulation of hypoxia-inducible factor 2α and decreases brain damage in rats. Neurosci Lett (2012) 0.78
Nuclear translocation and calpain-dependent reduction of Bcl-2 after neonatal cerebral hypoxia-ischemia. Brain Behav Immun (2009) 0.78
Isolation of recombinant phage antibodies targeting the hemagglutinin cleavage site of highly pathogenic avian influenza virus. PLoS One (2013) 0.78
Binding of the ERα and ARNT1 AF2 domains to exon 21 of the SRC1 isoform SRC1e is essential for estrogen- and dioxin-related transcription. J Cell Sci (2012) 0.78
[Role of cofilin phosphorylation in cell migration]. Tanpakushitsu Kakusan Koso (2006) 0.77
A novel pair of split venus fragments to detect protein-protein interactions by in vitro and in vivo bimolecular fluorescence complementation assays. Methods Mol Biol (2014) 0.77
Multifaceted roles of Furry proteins in invertebrates and vertebrates. J Biochem (2014) 0.76
Enhancement by cyclosporin A of taxol-induced apoptosis of human urinary bladder cancer cells. Urol Res (2002) 0.76
Effect of cyclosporin a on immediate early gene in rat global ischemia and its neuroprotection. J Pharmacol Sci (2006) 0.76
[Cell-penetrating peptide]. Nihon Yakurigaku Zasshi (2013) 0.75
Cytokine marker measurement in human neuroblastoma cells with supersensitive and multiplex assay: MUSTag technology. Acta Neurochir Suppl (2013) 0.75
Protein-based open sandwich immuno-PCR for sensitive detection of small biomarkers. Anal Sci (2013) 0.75