Published in J Biol Chem on November 26, 2003
Differential regulation of protrusion and polarity by PI3K during neutrophil motility in live zebrafish. Dev Cell (2010) 3.19
Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation. J Cell Biol (2004) 2.55
Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot. Nat Cell Biol (2009) 2.31
Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J Cell Biol (2005) 2.05
Cofilin dissociates Arp2/3 complex and branches from actin filaments. Curr Biol (2009) 1.98
Functions of cofilin in cell locomotion and invasion. Nat Rev Mol Cell Biol (2013) 1.95
Intracellular control of developmental and regenerative axon growth. Philos Trans R Soc Lond B Biol Sci (2006) 1.70
Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture. J Biol Chem (2010) 1.43
Enhanced cellular radiosensitivity induced by cofilin-1 over-expression is associated with reduced DNA repair capacity. Int J Radiat Biol (2013) 1.42
The slingshot family of phosphatases mediates Rac1 regulation of cofilin phosphorylation, laminin-332 organization, and motility behavior of keratinocytes. J Biol Chem (2007) 1.27
Akt-PDK1 complex mediates epidermal growth factor-induced membrane protrusion through Ral activation. Mol Biol Cell (2006) 1.15
Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin. EMBO J (2007) 1.14
A PLCβ/PI3Kγ-GSK3 signaling pathway regulates cofilin phosphatase slingshot2 and neutrophil polarization and chemotaxis. Dev Cell (2011) 1.10
Arp2/3- and cofilin-coordinated actin dynamics is required for insulin-mediated GLUT4 translocation to the surface of muscle cells. Mol Biol Cell (2010) 1.04
Dopamine D4 receptors regulate AMPA receptor trafficking and glutamatergic transmission in GABAergic interneurons of prefrontal cortex. J Neurosci (2009) 1.02
Loss of PTEN induces microtentacles through PI3K-independent activation of cofilin. Oncogene (2012) 0.96
Mitochondrial translocation of cofilin is required for allyl isothiocyanate-mediated cell death via ROCK1/PTEN/PI3K signaling pathway. Cell Commun Signal (2013) 0.92
PTEN directly activates the actin depolymerization factor cofilin-1 during PGE2-mediated inhibition of phagocytosis of fungi. Sci Signal (2012) 0.92
Small GTPases and phosphoinositides in the regulatory mechanisms of macropinosome formation and maturation. Front Physiol (2014) 0.90
Tropomodulin3 is a novel Akt2 effector regulating insulin-stimulated GLUT4 exocytosis through cortical actin remodeling. Nat Commun (2015) 0.89
LIM kinase has a dual role in regulating lamellipodium extension by decelerating the rate of actin retrograde flow and the rate of actin polymerization. J Biol Chem (2011) 0.88
Cofilin activation during podosome belt formation in osteoclasts. PLoS One (2012) 0.83
Redox regulation of 14-3-3ζ controls monocyte migration. Arterioscler Thromb Vasc Biol (2014) 0.80
Insulin receptor substrate-4 binds to Slingshot-1 phosphatase and promotes cofilin dephosphorylation. J Biol Chem (2014) 0.78
Ultrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell Responses. Front Immunol (2016) 0.76
PI3Kδ promotes CD4(+) T-cell interactions with antigen-presenting cells by increasing LFA-1 binding to ICAM-1. Immunol Cell Biol (2016) 0.75
Slingshot-1L, a cofilin phosphatase, induces primary breast cancer metastasis. Oncotarget (2017) 0.75
The genome of the mesopolyploid crop species Brassica rapa. Nat Genet (2011) 8.23
Orangutan cultures and the evolution of material culture. Science (2003) 6.06
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers. Cancer Res (2011) 6.02
Attenuated cold sensitivity in TRPM8 null mice. Neuron (2007) 4.73
Hippocampal LTP is accompanied by enhanced F-actin content within the dendritic spine that is essential for late LTP maintenance in vivo. Neuron (2003) 4.47
Structural basis of toll-like receptor 3 signaling with double-stranded RNA. Science (2008) 4.41
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways. Cell (2002) 4.35
Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome. Neuron (2005) 4.11
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-gamma and PTEN. Nature (2006) 4.09
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas. J Clin Invest (2004) 3.92
Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilin. Cell (2002) 3.83
Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nat Immunol (2002) 3.75
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates. Proc Natl Acad Sci U S A (2009) 3.39
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1. Nat Cell Biol (2006) 3.19
Nitrogen uptake, assimilation and remobilization in plants: challenges for sustainable and productive agriculture. Ann Bot (2010) 3.11
Homophilic Dscam interactions control complex dendrite morphogenesis. Neuron (2007) 3.08
The molecular mechanism governing the oncogenic potential of SOX2 in breast cancer. J Biol Chem (2008) 3.01
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54. Nat Genet (2010) 2.95
Melamine related bilateral renal calculi in 50 children: single center experience in clinical diagnosis and treatment. J Urol (2010) 2.83
Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice. J Neurosci (2009) 2.76
High resolution genomic analysis of sporadic breast cancer using array-based comparative genomic hybridization. Breast Cancer Res (2005) 2.72
VisANT 3.5: multi-scale network visualization, analysis and inference based on the gene ontology. Nucleic Acids Res (2009) 2.71
EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2. Nature (2013) 2.67
Dissecting multiple steps of GLUT4 trafficking and identifying the sites of insulin action. Cell Metab (2007) 2.63
Atypical angiopoietin-like protein that regulates ANGPTL3. Proc Natl Acad Sci U S A (2012) 2.62
Common genetic variants in pre-microRNAs were associated with increased risk of breast cancer in Chinese women. Hum Mutat (2009) 2.60
Identification of the pollen determinant of S-RNase-mediated self-incompatibility. Nature (2004) 2.53
Myocardial infarct size measurement in the mouse chronic infarction model: comparison of area- and length-based approaches. J Appl Physiol (1985) (2007) 2.52
Preoperative predictors for mortality following hip fracture surgery: a systematic review and meta-analysis. Injury (2011) 2.51
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proc Natl Acad Sci U S A (2013) 2.49
Polarized transport of Frizzled along the planar microtubule arrays in Drosophila wing epithelium. Dev Cell (2006) 2.47
Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes. J Clin Endocrinol Metab (2003) 2.46
Central and autonomic nervous system interaction is altered by short-term meditation. Proc Natl Acad Sci U S A (2009) 2.45
A double-blind, placebo-controlled trial assessing pramlintide treatment in the setting of intensive insulin therapy in type 1 diabetes. Diabetes Care (2006) 2.40
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity. J Clin Invest (2006) 2.38
Diabetes mellitus and risk of hepatocellular carcinoma: a systematic review and meta-analysis. Diabetes Metab Res Rev (2012) 2.38
The yak genome and adaptation to life at high altitude. Nat Genet (2012) 2.34
Hemorrhagic fever caused by a novel Bunyavirus in China: pathogenesis and correlates of fatal outcome. Clin Infect Dis (2011) 2.34
Polarity and intracellular compartmentalization of Drosophila neurons. Neural Dev (2007) 2.32
Meta-analysis of a possible signal of increased mortality associated with cefepime use. Clin Infect Dis (2010) 2.31
Genome-wide functional analysis of human cell-cycle regulators. Proc Natl Acad Sci U S A (2006) 2.31
Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshot. Nat Cell Biol (2009) 2.31
The ecology, genetic diversity, and phylogeny of Huaiyangshan virus in China. J Virol (2011) 2.23
Shortstop recruits EB1/APC1 and promotes microtubule assembly at the muscle-tendon junction. Curr Biol (2003) 2.20
Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus. Nat Neurosci (2010) 2.18
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis. Genes Dev (2005) 2.18
Major issues and challenges of influenza pandemic preparedness in developing countries. Emerg Infect Dis (2008) 2.16
Hemorrhagic fever caused by a novel tick-borne Bunyavirus in Huaiyangshan, China. Zhonghua Liu Xing Bing Xue Za Zhi (2011) 2.15
GETDB, a database compiling expression patterns and molecular locations of a collection of Gal4 enhancer traps. Genesis (2002) 2.14
A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodia. J Cell Biol (2004) 2.14
High eosinophil count: a potential biomarker for assessing successful omalizumab treatment effects. J Allergy Clin Immunol (2013) 2.14
Integration of estrogen and Wnt signaling circuits by the polycomb group protein EZH2 in breast cancer cells. Mol Cell Biol (2007) 2.14
Genome-wide association study identifies a susceptibility locus for schizophrenia in Han Chinese at 11p11.2. Nat Genet (2011) 2.13
Urban health insurance reform and coverage in China using data from National Health Services Surveys in 1998 and 2003. BMC Health Serv Res (2007) 2.10
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based HTS assay. Part 5: modifications of the 2- and 3-positions. Bioorg Med Chem Lett (2007) 2.10
Elevated left ventricular outflow tract velocities on exercise stress echocardiography may be a normal physiologic response in healthy youth. J Am Soc Echocardiogr (2013) 2.06
Spatial and temporal regulation of cofilin activity by LIM kinase and Slingshot is critical for directional cell migration. J Cell Biol (2005) 2.05
Sleep-induced hypoxaemia in patients with chronic obstructive pulmonary disease. Br J Hosp Med (Lond) (2013) 2.04
Myasthenia gravis and Guillain-Barré cooccurrence syndrome. Am J Emerg Med (2013) 2.04
Spatial control of branching within dendritic arbors by dynein-dependent transport of Rab5-endosomes. Nat Cell Biol (2008) 2.04
Detection of biomarkers with a multiplex quantitative proteomic platform in cerebrospinal fluid of patients with neurodegenerative disorders. J Alzheimers Dis (2006) 2.00
Theoretical analysis of wavefront aberration caused by treatment decentration and transition zone after custom myopic laser refractive surgery. J Cataract Refract Surg (2013) 1.99
High prevalence of obstructive sleep apnea and its association with renal function among nondialysis chronic kidney disease patients in Japan: a cross-sectional study. Clin J Am Soc Nephrol (2011) 1.98
Anatomic proximity of the peroneal nerve to the posterolateral corner of the knee determined by MR imaging. Knee (2012) 1.97
Epithelial-mesenchymal transition induced by TNF-α requires NF-κB-mediated transcriptional upregulation of Twist1. Cancer Res (2012) 1.97
Enterovirus 68 among children with severe acute respiratory infection, the Philippines. Emerg Infect Dis (2011) 1.96
Muscle-specific Pten deletion protects against insulin resistance and diabetes. Mol Cell Biol (2005) 1.93
Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. J Cell Biol (2007) 1.93
Genetic variants in fibroblast growth factor receptor 2 (FGFR2) contribute to susceptibility of breast cancer in Chinese women. Carcinogenesis (2008) 1.87
Pten controls lung morphogenesis, bronchioalveolar stem cells, and onset of lung adenocarcinomas in mice. J Clin Invest (2007) 1.86
Distinct developmental modes and lesion-induced reactions of dendrites of two classes of Drosophila sensory neurons. J Neurosci (2003) 1.86
Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development (2003) 1.80
Expression of Cyr61, CTGF, and WISP-1 correlates with clinical features of lung cancer. PLoS One (2007) 1.79
Respiratory viruses augment the adhesion of bacterial pathogens to respiratory epithelium in a viral species- and cell type-dependent manner. J Virol (2006) 1.78
Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia. Nat Genet (2013) 1.77
VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses. J Exp Med (2011) 1.77
Metabolic syndrome meets osteoarthritis. Nat Rev Rheumatol (2012) 1.75
Emergence of a new multidrug-resistant serotype X variant in an epidemic clone of Shigella flexneri. J Clin Microbiol (2009) 1.71
VisANT 4.0: Integrative network platform to connect genes, drugs, diseases and therapies. Nucleic Acids Res (2013) 1.71
Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80. Nature (2008) 1.71
Retracted Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice. Nat Med (2004) 1.69
Density of organic matrix of native mineralized bone measured by water- and fat-suppressed proton projection MRI. Magn Reson Med (2003) 1.68
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten. Proc Natl Acad Sci U S A (2004) 1.67
Comparison between computer-assisted-navigation and conventional total knee arthroplasties in patients undergoing simultaneous bilateral procedures: a randomized clinical trial. J Bone Joint Surg Am (2011) 1.67
Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex. Neuron (2010) 1.66
Circulating blood cells function as a surveillance system for damaged tissue in Drosophila larvae. Proc Natl Acad Sci U S A (2008) 1.65
Interventions for accelerating orthodontic tooth movement: a systematic review. Angle Orthod (2012) 1.65
Squamous cell carcinoma arising in lichen simplex chronicus. Eur J Dermatol (2010) 1.64
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR). Proc Natl Acad Sci U S A (2010) 1.64
A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of function. Proc Natl Acad Sci U S A (2005) 1.64
Atypical cadherins Dachsous and Fat control dynamics of noncentrosomal microtubules in planar cell polarity. Dev Cell (2010) 1.63
Kaposi's sarcoma-associated herpesvirus lytic origin (ori-Lyt)-dependent DNA replication: identification of the ori-Lyt and association of K8 bZip protein with the origin. J Virol (2003) 1.63
Human circulating microRNA-1 and microRNA-126 as potential novel indicators for acute myocardial infarction. Int J Biol Sci (2012) 1.63
Antiemetic placebo: reduce adverse drug interactions between chemotherapeutic agents and antiemetic drugs in cancer patients. Med Hypotheses (2007) 1.62