Edward H Leiter

Author PubWeight™ 44.96‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Mouse models of diabetic nephropathy. J Am Soc Nephrol 2009 3.74
2 Lipid metabolome-wide effects of the PPARgamma agonist rosiglitazone. J Lipid Res 2002 2.30
3 Cdcs1, a major colitogenic locus in mice, regulates innate and adaptive immune response to enteric bacterial antigens. Gastroenterology 2005 1.81
4 Resistance of C57BL/6 mice to amoebiasis is mediated by nonhemopoietic cells but requires hemopoietic IL-10 production. J Immunol 2006 1.77
5 Diet-induced obesity in two C57BL/6 substrains with intact or mutant nicotinamide nucleotide transhydrogenase (Nnt) gene. Obesity (Silver Spring) 2010 1.38
6 Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes. Am J Physiol Endocrinol Metab 2007 1.23
7 Deconstructing and reconstructing obesity-induced diabetes (diabesity) in mice. Diabetes 2002 1.22
8 Refined histopathologic scoring system improves power to detect colitis QTL in mice. Mamm Genome 2004 1.20
9 New mouse model to study islet transplantation in insulin-dependent diabetes mellitus. Transplantation 2002 1.17
10 Four additional mouse crosses improve the lipid QTL landscape and identify Lipg as a QTL gene. J Lipid Res 2009 1.16
11 Caspase-1 is not required for type 1 diabetes in the NOD mouse. Diabetes 2004 1.16
12 CD38 controls ADP-ribosyltransferase-2-catalyzed ADP-ribosylation of T cell surface proteins. J Immunol 2005 1.12
13 Targeted disruption of CD38 accelerates autoimmune diabetes in NOD/Lt mice by enhancing autoimmunity in an ADP-ribosyltransferase 2-dependent fashion. J Immunol 2006 1.06
14 Adverse hepatic and cardiac responses to rosiglitazone in a new mouse model of type 2 diabetes: relation to dysregulated phosphatidylcholine metabolism. Vascul Pharmacol 2006 1.04
15 Mechanisms underlying resistance of pancreatic islets from ALR/Lt mice to cytokine-induced destruction. J Immunol 2005 1.04
16 Proteasome inhibition alters glucose-stimulated (pro)insulin secretion and turnover in pancreatic {beta}-cells. J Biol Chem 2005 1.03
17 Absence of a reductase, NCB5OR, causes insulin-deficient diabetes. Proc Natl Acad Sci U S A 2004 1.03
18 Genetic and environmental context determines the course of colitis developing in IL-10-deficient mice. Inflamm Bowel Dis 2002 1.01
19 P2X7 receptor-dependent and -independent T cell death is induced by nicotinamide adenine dinucleotide. J Immunol 2005 1.00
20 A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein. FEBS Lett 2006 0.94
21 Cdcs1 a major colitis susceptibility locus in mice; subcongenic analysis reveals genetic complexity. Inflamm Bowel Dis 2010 0.93
22 Genetic analysis of resistance to Type-1 Diabetes in ALR/Lt mice, a NOD-related strain with defenses against autoimmune-mediated diabetogenic stress. Immunogenetics 2003 0.92
23 CD38 is required for the peripheral survival of immunotolerogenic CD4+ invariant NK T cells in nonobese diabetic mice. J Immunol 2006 0.91
24 "Agouti NOD": identification of a CBA-derived Idd locus on Chromosome 7 and its use for chimera production with NOD embryonic stem cells. Mamm Genome 2005 0.90
25 Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice. J Immunol 2011 0.88
26 Genetic control of neutrophil superoxide production in diabetes-resistant ALR/Lt mice. Free Radic Biol Med 2002 0.88
27 Pharmacogenetic analysis of rosiglitazone-induced hepatosteatosis in new mouse models of type 2 diabetes. Diabetes 2005 0.88
28 mt-Nd2(a) Modifies resistance against autoimmune type 1 diabetes in NOD mice at the level of the pancreatic β-cell. Diabetes 2010 0.86
29 Major histocompatibility complex-linked diabetes susceptibility in NOD/Lt mice: subcongenic analysis localizes a component of Idd16 at the H2-D end of the diabetogenic H2(g7) complex. Diabetes 2005 0.86
30 Flow cytometric and immunoblot assays for cell surface ADP-ribosylation using a monoclonal antibody specific for ethenoadenosine. Anal Biochem 2003 0.86
31 Gene expression profiling of leukemic cells and primary thymocytes predicts a signature for apoptotic sensitivity to glucocorticoids. Cancer Cell Int 2007 0.85
32 The diabetes-prone NZO/HlLt strain. I. Immunophenotypic comparison to the related NZB/BlNJ and NZW/LacJ strains. Lab Invest 2002 0.85
33 Commonalities of genetic resistance to spontaneous autoimmune and free radical--mediated diabetes. Free Radic Biol Med 2008 0.85
34 Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: I. Pathophysiological analysis. Diabetes 2005 0.85
35 ALS/Lt: a new type 2 diabetes mouse model associated with low free radical scavenging potential. Diabetes 2004 0.84
36 Contributions of dysregulated energy metabolism to type 2 diabetes development in NZO/H1Lt mice with polygenic obesity. Metabolism 2004 0.84
37 Novel leptin receptor mutation in NOD/LtJ mice suppresses type 1 diabetes progression: II. Immunologic analysis. Diabetes 2006 0.84
38 Animal models of diabetic uropathy. J Urol 2009 0.82
39 The diabetes-prone NZO/Hl strain. II. Pancreatic immunopathology. Lab Invest 2002 0.78
40 Adoptive transfer of islet antigen-autoreactive T cell clones to transgenic NOD.Ea(d)mice induces diabetes indicating a lack of I-E mediated protection against activated effector T cells. J Autoimmun 2003 0.76
41 Tracking autoimmune T cells in diabetes. J Clin Invest 2003 0.75
42 Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation. Novartis Found Symp 2008 0.75
43 Anti-insulin receptor autoantibodies are not required for type 2 diabetes pathogenesis in NZL/Lt mice, a New Zealand obese (NZO)-derived mouse strain. Exp Diabesity Res 2004 0.75
44 The diabetes-prone NZO/Hl strain. Proliferation capacity of beta cells in hyperinsulinemia and hyperglycemia. Arch Physiol Biochem 2006 0.75