PubRank

Neil F Fairweather

Author PubWeight™ 40.02‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet 2006 8.02
2 Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts. Infect Immun 2009 3.36
3 The Clostridium difficile spo0A gene is a persistence and transmission factor. Infect Immun 2012 2.02
4 Structural insights into the molecular organization of the S-layer from Clostridium difficile. Mol Microbiol 2009 1.71
5 Binding of Clostridium difficile surface layer proteins to gastrointestinal tissues. Infect Immun 2002 1.55
6 Clostridium difficile has two parallel and essential Sec secretion systems. J Biol Chem 2011 1.50
7 Distinctive profiles of infection and pathology in hamsters infected with Clostridium difficile strains 630 and B1. Infect Immun 2009 1.35
8 A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein. Mol Microbiol 2009 1.30
9 Revised nomenclature of Clostridium difficile toxins and associated genes. J Med Microbiol 2005 1.28
10 Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B. Infect Immun 2011 1.24
11 Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress. J Med Microbiol 2008 1.20
12 Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS. J Mol Biol 2010 1.15
13 The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. PLoS Pathog 2011 1.11
14 Immunoreactive cell wall proteins of Clostridium difficile identified by human sera. J Med Microbiol 2008 1.08
15 Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile. J Bacteriol 2011 0.98
16 Chemical probes of surface layer biogenesis in Clostridium difficile. ACS Chem Biol 2010 0.97
17 A proposed nomenclature for cell wall proteins of Clostridium difficile. J Med Microbiol 2011 0.94
18 Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores. PLoS One 2013 0.92
19 Functional characterization of OXA-57, a class D beta-lactamase from Burkholderia pseudomallei. Antimicrob Agents Chemother 2005 0.88
20 CbpA: a novel surface exposed adhesin of Clostridium difficile targeting human collagen. Cell Microbiol 2013 0.87
21 The spore-associated protein BclA1 affects the susceptibility of animals to colonization and infection by Clostridium difficile. Mol Microbiol 2014 0.85
22 Clostridium difficile cell wall protein CwpV undergoes enzyme-independent intramolecular autoproteolysis. J Biol Chem 2011 0.82
23 A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice. Vaccine 2012 0.82
24 Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding. Mol Immunol 2010 0.82
25 Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII. Mol Microbiol 2015 0.81
26 Novel inhibitors of surface layer processing in Clostridium difficile. Bioorg Med Chem 2011 0.78
27 A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells. J Drug Target 2003 0.78
28 Vaccination against type F botulinum toxin using attenuated Salmonella enterica var Typhimurium strains expressing the BoNT/F H(C) fragment. Vaccine 2003 0.77
29 Immunization does not interfere with uptake and transport by motor neurons of the binding fragment of tetanus toxin. J Neurosci Res 2006 0.75