Published in Infect Immun on June 29, 2009
Impacts of biodiversity on the emergence and transmission of infectious diseases. Nature (2010) 6.55
Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J (2010) 5.43
Vancomycin-resistant Enterococcus domination of intestinal microbiota is enabled by antibiotic treatment in mice and precedes bloodstream invasion in humans. J Clin Invest (2010) 4.95
Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens. Nature (2013) 4.43
Role of the gut microbiota in immunity and inflammatory disease. Nat Rev Immunol (2013) 4.34
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. PLoS Pathog (2012) 3.81
Airway microbiota and pathogen abundance in age-stratified cystic fibrosis patients. PLoS One (2010) 3.38
Sequencing ancient calcified dental plaque shows changes in oral microbiota with dietary shifts of the Neolithic and Industrial revolutions. Nat Genet (2013) 3.03
Microbiota-mediated colonization resistance against intestinal pathogens. Nat Rev Immunol (2013) 2.89
Profound alterations of intestinal microbiota following a single dose of clindamycin results in sustained susceptibility to Clostridium difficile-induced colitis. Infect Immun (2011) 2.87
Control of pathogens and pathobionts by the gut microbiota. Nat Immunol (2013) 2.84
Role of the commensal microbiota in normal and pathogenic host immune responses. Cell Host Microbe (2011) 2.46
The interplay between microbiome dynamics and pathogen dynamics in a murine model of Clostridium difficile Infection. Gut Microbes (2011) 2.37
Clostridium difficile toxin CDT induces formation of microtubule-based protrusions and increases adherence of bacteria. PLoS Pathog (2009) 2.29
Culturing of 'unculturable' human microbiota reveals novel taxa and extensive sporulation. Nature (2016) 2.17
The Clostridium difficile spo0A gene is a persistence and transmission factor. Infect Immun (2012) 2.02
Metabolism of bile salts in mice influences spore germination in Clostridium difficile. PLoS One (2010) 1.87
Intestinal colonization resistance. Immunology (2013) 1.85
Role of the gut microbiota in defining human health. Expert Rev Anti Infect Ther (2010) 1.73
Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis. Sci Transl Med (2012) 1.71
Interaction between the intestinal microbiota and host in Clostridium difficile colonization resistance. Trends Microbiol (2012) 1.70
Proton Pump Inhibitors Alter Specific Taxa in the Human Gastrointestinal Microbiome: A Crossover Trial. Gastroenterology (2015) 1.69
From superspreaders to disease hotspots: linking transmission across hosts and space. Front Ecol Environ (2012) 1.68
Innate Immune Defenses Mediated by Two ILC Subsets Are Critical for Protection against Acute Clostridium difficile Infection. Cell Host Microbe (2015) 1.66
Effect of antibiotic treatment on the intestinal metabolome. Antimicrob Agents Chemother (2011) 1.64
A modified R-type bacteriocin specifically targeting Clostridium difficile prevents colonization of mice without affecting gut microbiota diversity. MBio (2015) 1.59
Toll-like receptor 5 stimulation protects mice from acute Clostridium difficile colitis. Infect Immun (2011) 1.53
Multiple factors modulate biofilm formation by the anaerobic pathogen Clostridium difficile. J Bacteriol (2012) 1.47
'Blooming' in the gut: how dysbiosis might contribute to pathogen evolution. Nat Rev Microbiol (2013) 1.45
Critical role for MyD88-mediated neutrophil recruitment during Clostridium difficile colitis. Infect Immun (2012) 1.43
A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins. PLoS Pathog (2011) 1.39
Mouse relapse model of Clostridium difficile infection. Infect Immun (2011) 1.36
Antibiotics, microbiota, and immune defense. Trends Immunol (2012) 1.33
Use of purified Clostridium difficile spores to facilitate evaluation of health care disinfection regimens. Appl Environ Microbiol (2010) 1.32
Oral and airway microbiota in HIV-infected pneumonia patients. J Clin Microbiol (2012) 1.30
Cefoperazone-treated mice as an experimental platform to assess differential virulence of Clostridium difficile strains. Gut Microbes (2011) 1.29
The anti-sigma factor TcdC modulates hypervirulence in an epidemic BI/NAP1/027 clinical isolate of Clostridium difficile. PLoS Pathog (2011) 1.28
Reductions in intestinal Clostridiales precede the development of nosocomial Clostridium difficile infection. Microbiome (2013) 1.26
Microbiota dynamics in patients treated with fecal microbiota transplantation for recurrent Clostridium difficile infection. PLoS One (2013) 1.24
Microbiota-mediated inflammation and antimicrobial defense in the intestine. Annu Rev Immunol (2015) 1.23
Surface layers of Clostridium difficile endospores. J Bacteriol (2011) 1.22
Clostridium difficile toxins: mediators of inflammation. J Innate Immun (2012) 1.21
Characterisation of Clostridium difficile biofilm formation, a role for Spo0A. PLoS One (2012) 1.21
Salmonella-induced mucosal lectin RegIIIβ kills competing gut microbiota. PLoS One (2011) 1.20
Clostridium difficile infection: An overview of the disease and its pathogenesis, epidemiology and interventions. Gut Microbes (2010) 1.19
Adaptive strategies and pathogenesis of Clostridium difficile from in vivo transcriptomics. Infect Immun (2013) 1.17
Models for the study of Clostridium difficile infection. Gut Microbes (2012) 1.16
Cyclic diguanylate inversely regulates motility and aggregation in Clostridium difficile. J Bacteriol (2012) 1.14
The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function. PLoS Pathog (2011) 1.11
Clostridium difficile and the microbiota. J Clin Invest (2014) 1.09
Identification of a genetic locus responsible for antimicrobial peptide resistance in Clostridium difficile. Infect Immun (2010) 1.08
The enterotoxicity of Clostridium difficile toxins. Toxins (Basel) (2010) 1.07
Both, toxin A and toxin B, are important in Clostridium difficile infection. Gut Microbes (2011) 1.06
No vacancy: how beneficial microbes cooperate with immunity to provide colonization resistance to pathogens. J Immunol (2015) 1.05
Antibiotics and the Human Gut Microbiome: Dysbioses and Accumulation of Resistances. Front Microbiol (2016) 1.03
The intestinal microbiota and susceptibility to infection in immunocompromised patients. Curr Opin Infect Dis (2013) 1.01
Cystic fibrosis transmembrane conductance regulator knockout mice exhibit aberrant gastrointestinal microbiota. Gut Microbes (2012) 1.01
The lung microbiome of Ugandan HIV-infected pneumonia patients is compositionally and functionally distinct from that of San Franciscan patients. PLoS One (2014) 1.00
Inference of Network Dynamics and Metabolic Interactions in the Gut Microbiome. PLoS Comput Biol (2015) 0.99
Variations in virulence and molecular biology among emerging strains of Clostridium difficile. Microbiol Mol Biol Rev (2013) 0.99
Emerging insights on intestinal dysbiosis during bacterial infections. Curr Opin Microbiol (2013) 0.99
Functional characterization of Clostridium difficile spore coat proteins. J Bacteriol (2013) 0.98
Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile. J Bacteriol (2011) 0.98
Muricholic acids inhibit Clostridium difficile spore germination and growth. PLoS One (2013) 0.98
Clostridium difficile spore-macrophage interactions: spore survival. PLoS One (2012) 0.97
The host immune response to Clostridium difficile infection. Ther Adv Infect Dis (2013) 0.96
Spore Cortex Hydrolysis Precedes Dipicolinic Acid Release during Clostridium difficile Spore Germination. J Bacteriol (2015) 0.96
Fecal microbiota transplantation: effectiveness, complexities, and lingering concerns. Mucosal Immunol (2014) 0.95
The agr locus regulates virulence and colonization genes in Clostridium difficile 027. J Bacteriol (2013) 0.95
Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease. Infect Immun (2015) 0.93
Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism. BMC Genomics (2014) 0.93
Acute infection of mice with Clostridium difficile leads to eIF2α phosphorylation and pro-survival signalling as part of the mucosal inflammatory response. Immunology (2013) 0.93
Salmonella transiently reside in luminal neutrophils in the inflamed gut. PLoS One (2012) 0.92
Effectiveness of fecal-derived microbiota transfer using orally administered capsules for recurrent Clostridium difficile infection. BMC Infect Dis (2015) 0.92
Identification of a Novel Lipoprotein Regulator of Clostridium difficile Spore Germination. PLoS Pathog (2015) 0.91
Stereomicroscopic 3D-pattern profiling of murine and human intestinal inflammation reveals unique structural phenotypes. Nat Commun (2015) 0.91
Cyclic di-GMP riboswitch-regulated type IV pili contribute to aggregation of Clostridium difficile. J Bacteriol (2014) 0.91
The Etiology and Pathogenesis of Chronic Rhinosinusitis: a Review of Current Hypotheses. Curr Allergy Asthma Rep (2015) 0.91
Clostridium difficile colitis: pathogenesis and host defence. Nat Rev Microbiol (2016) 0.90
Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis. Front Microbiol (2015) 0.89
Transient fecal shedding and limited animal-to-animal transmission of Clostridium difficile by naturally infected finishing feedlot cattle. Appl Environ Microbiol (2011) 0.89
Murine models to study Clostridium difficile infection and transmission. Anaerobe (2013) 0.89
Prevention of Clostridium difficile spore formation by sub-inhibitory concentrations of tigecycline and piperacillin/tazobactam. BMC Infect Dis (2014) 0.88
The intestinal microbiota and viral susceptibility. Front Microbiol (2011) 0.88
Clostridium difficile virulence factors: Insights into an anaerobic spore-forming pathogen. Gut Microbes (2014) 0.86
The Enteric Two-Step: nutritional strategies of bacterial pathogens within the gut. Cell Microbiol (2014) 0.85
Disruption of the Gut Microbiome: Clostridium difficile Infection and the Threat of Antibiotic Resistance. Genes (Basel) (2015) 0.84
Biofilm formation by Clostridium difficile. Gut Microbes (2013) 0.84
Hype or hypervirulence: a reflection on problematic C. difficile strains. Virulence (2013) 0.83
Protection from Clostridium difficile infection in CD4 T Cell- and polymeric immunoglobulin receptor-deficient mice. Infect Immun (2013) 0.83
SMT19969 for Clostridium difficile infection (CDI): in vivo efficacy compared with fidaxomicin and vancomycin in the hamster model of CDI. J Antimicrob Chemother (2015) 0.82
The post-translational modification of the Clostridium difficile flagellin affects motility, cell surface properties and virulence. Mol Microbiol (2014) 0.82
Regulation of Clostridium difficile spore germination by the CspA pseudoprotease domain. Biochimie (2015) 0.82
Shedding light on the microbial community of the macropod foregut using 454-amplicon pyrosequencing. PLoS One (2013) 0.81
Interleukin-22 and CD160 play additive roles in the host mucosal response to Clostridium difficile infection in mice. Immunology (2015) 0.81
Crossing the scale from within-host infection dynamics to between-host transmission fitness: a discussion of current assumptions and knowledge. Philos Trans R Soc Lond B Biol Sci (2015) 0.81
Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliC. Emerg Microbes Infect (2016) 0.80
When pathogenic bacteria meet the intestinal microbiota. Philos Trans R Soc Lond B Biol Sci (2016) 0.79
Regulation of Type IV Pili Contributes to Surface Behaviors of Historical and Epidemic Strains of Clostridium difficile. J Bacteriol (2015) 0.79
Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl Environ Microbiol (2006) 57.72
Diversity of the human intestinal microbial flora. Science (2005) 49.64
Introducing DOTUR, a computer program for defining operational taxonomic units and estimating species richness. Appl Environ Microbiol (2005) 31.06
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell (2004) 29.32
Evolution of mammals and their gut microbes. Science (2008) 21.40
Unravelling the pathogenesis of inflammatory bowel disease. Nature (2007) 18.52
Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity (1998) 18.12
The pervasive effects of an antibiotic on the human gut microbiota, as revealed by deep 16S rRNA sequencing. PLoS Biol (2008) 16.57
Superspreading and the effect of individual variation on disease emergence. Nature (2005) 14.01
Clostridium difficile--more difficult than ever. N Engl J Med (2008) 12.12
Heterogeneities in the transmission of infectious agents: implications for the design of control programs. Proc Natl Acad Sci U S A (1997) 9.07
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Reproducible community dynamics of the gastrointestinal microbiota following antibiotic perturbation. Infect Immun (2009) 7.48
Molecular genetics of sporulation in Bacillus subtilis. Annu Rev Genet (1996) 7.17
Clinical practice. Antibiotic-associated diarrhea. N Engl J Med (2002) 7.13
Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host. Infect Immun (2003) 6.82
Asymptomatic carriage of Clostridium difficile and serum levels of IgG antibody against toxin A. N Engl J Med (2000) 6.24
Decreased diversity of the fecal Microbiome in recurrent Clostridium difficile-associated diarrhea. J Infect Dis (2008) 6.21
Paneth cells directly sense gut commensals and maintain homeostasis at the intestinal host-microbial interface. Proc Natl Acad Sci U S A (2008) 5.78
Toxin B is essential for virulence of Clostridium difficile. Nature (2009) 5.49
Host-induced epidemic spread of the cholera bacterium. Nature (2002) 5.20
Effect of antibiotic therapy on the density of vancomycin-resistant enterococci in the stool of colonized patients. N Engl J Med (2000) 5.08
Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits. Nature (2008) 4.87
Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents. Clin Infect Dis (2007) 4.77
Narrative review: the new epidemic of Clostridium difficile-associated enteric disease. Ann Intern Med (2006) 4.64
Colonization resistance. Antimicrob Agents Chemother (1994) 4.51
Use of sodium taurocholate to enhance spore recovery on a medium selective for Clostridium difficile. J Clin Microbiol (1982) 4.35
The ClosTron: a universal gene knock-out system for the genus Clostridium. J Microbiol Methods (2007) 4.20
Long-term ecological impacts of antibiotic administration on the human intestinal microbiota. ISME J (2007) 3.92
Antibiotic-induced perturbations of the intestinal microbiota alter host susceptibility to enteric infection. Infect Immun (2008) 3.68
A mouse model of Clostridium difficile-associated disease. Gastroenterology (2008) 3.65
Emergence of Clostridium difficile infection due to a new hypervirulent strain, polymerase chain reaction ribotype 078. Clin Infect Dis (2008) 3.49
The role of microbiota in infectious disease. Trends Microbiol (2008) 3.11
Comparative phylogenomics of Clostridium difficile reveals clade specificity and microevolution of hypervirulent strains. J Bacteriol (2006) 3.05
Host transmission of Salmonella enterica serovar Typhimurium is controlled by virulence factors and indigenous intestinal microbiota. Infect Immun (2007) 2.80
Construction and analysis of chromosomal Clostridium difficile mutants. Mol Microbiol (2006) 2.65
A comparative genomic view of clostridial sporulation and physiology. Nat Rev Microbiol (2005) 2.49
Prolonged impact of antibiotics on intestinal microbial ecology and susceptibility to enteric Salmonella infection. Infect Immun (2009) 2.26
Clostridium difficile in gnotobiotic mice. Infect Immun (1980) 2.17
Efficiency of various bile salt preparations for stimulation of Clostridium difficile spore germination. J Clin Microbiol (1983) 2.15
In vivo bioluminescence imaging of the murine pathogen Citrobacter rodentium. Infect Immun (2006) 2.07
Efficacy of hospital cleaning agents and germicides against epidemic Clostridium difficile strains. Infect Control Hosp Epidemiol (2007) 2.06
Measures to control and prevent Clostridium difficile infection. Clin Infect Dis (2008) 2.04
Infection control measures to limit the spread of Clostridium difficile. Clin Microbiol Infect (2008) 2.01
Clostridium difficile: an important pathogen of food animals. Anaerobe (2005) 2.01
Clindamycin, cephalosporins, fluoroquinolones, and Clostridium difficile-associated diarrhea: this is an antimicrobial resistance problem. Clin Infect Dis (2004) 1.98
Mortality of patients with antibiotic-associated diarrhoea: the impact of Clostridium difficile. J Hosp Infect (2008) 1.91
Modelling infectious disease - time to think outside the box? Nat Rev Microbiol (2006) 1.82
The roles of gamma 1 heavy chain membrane expression and cytoplasmic tail in IgG1 responses. Science (1997) 1.80
The myeloid differentiation factor 88 (MyD88) is required for CD4+ T cell effector function in a murine model of inflammatory bowel disease. J Immunol (2008) 1.75
Pathogenesis of Clostridium difficile infection. J Antimicrob Chemother (1998) 1.72
Clostridium difficile colonization in healthy adults: transient colonization and correlation with enterococcal colonization. J Med Microbiol (2004) 1.62
Is Clostridium difficile-associated infection a potentially zoonotic and foodborne disease? Clin Microbiol Infect (2007) 1.56
Infection of hamsters with historical and epidemic BI types of Clostridium difficile. J Infect Dis (2007) 1.29
Clostridium difficile colitis causing toxic megacolon, severe sepsis and multiple organ dysfunction syndrome. Intensive Care Med (2003) 1.28
Isolation and characterisation of toxin A-negative, toxin B-positive Clostridium difficile in Dublin, Ireland. Clin Microbiol Infect (2007) 1.13
Clostridium difficile: from obscurity to superbug. Br J Biomed Sci (2008) 1.12
Clostridium difficile and acute respiratory distress syndrome. Heart Lung (2004) 1.11
Interaction of enteric bacterial pathogens with murine embryonic stem cells. Infect Immun (2008) 1.03
Comparison of alcohol shock enrichment and selective enrichment for the isolation of Clostridium difficile. Epidemiol Infect (1987) 1.01
Clostridium difficile infection. Lancet (2008) 1.01
Clostridium difficile causing acute renal failure: case presentation and review. World J Gastroenterol (2005) 0.92
Relationship between levels of Clostridium difficile toxin A and toxin B and cecal lesions in gnotobiotic mice. Infect Immun (1989) 0.91
The effect of an antibiotic on the susceptibility of the mouse's intestinal tract to Salmonella infection. Antibiot Annu (1957) 0.84
Colitis associated with Clostridium difficile in specific-pathogen-free C3H-scid mice. J Vet Med Sci (2007) 0.79
A human gut microbial gene catalogue established by metagenomic sequencing. Nature (2010) 43.63
The minimum information about a genome sequence (MIGS) specification. Nat Biotechnol (2008) 31.04
Enterotypes of the human gut microbiome. Nature (2011) 24.36
High-throughput sequencing provides insights into genome variation and evolution in Salmonella Typhi. Nat Genet (2008) 19.97
ACT: the Artemis Comparison Tool. Bioinformatics (2005) 17.91
Requirement of bic/microRNA-155 for normal immune function. Science (2007) 16.24
Evolution of MRSA during hospital transmission and intercontinental spread. Science (2010) 13.34
Typhoid fever. N Engl J Med (2002) 12.96
Prepublication data sharing. Nature (2009) 12.24
Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database. Bioinformatics (2008) 9.17
Rapid pneumococcal evolution in response to clinical interventions. Science (2011) 9.09
Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci U S A (2004) 8.95
The zebrafish reference genome sequence and its relationship to the human genome. Nature (2013) 8.52
The multidrug-resistant human pathogen Clostridium difficile has a highly mobile, mosaic genome. Nat Genet (2006) 8.02
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota. PLoS Biol (2007) 7.58
Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei. Proc Natl Acad Sci U S A (2004) 7.30
Whole-genome sequencing to delineate Mycobacterium tuberculosis outbreaks: a retrospective observational study. Lancet Infect Dis (2012) 7.18
The complete genome sequence of Mycobacterium bovis. Proc Natl Acad Sci U S A (2003) 6.79
Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus: a descriptive study. Lancet Infect Dis (2012) 6.64
Genetic analysis of the capsular biosynthetic locus from all 90 pneumococcal serotypes. PLoS Genet (2006) 6.43
Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak. N Engl J Med (2012) 6.36
GeneDB: a resource for prokaryotic and eukaryotic organisms. Nucleic Acids Res (2004) 6.30
The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet (2005) 6.22
Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study. Lancet Infect Dis (2011) 6.08
CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms. J Exp Med (2003) 6.00
The genome of the blood fluke Schistosoma mansoni. Nature (2009) 5.94
Multidrug-resistant Salmonella enterica serovar paratyphi A harbors IncHI1 plasmids similar to those found in serovar typhi. J Bacteriol (2007) 5.88
Evidence for several waves of global transmission in the seventh cholera pandemic. Nature (2011) 5.62
DNAPlotter: circular and linear interactive genome visualization. Bioinformatics (2008) 5.49
Dominant and diet-responsive groups of bacteria within the human colonic microbiota. ISME J (2010) 5.43
Microevolution and history of the plague bacillus, Yersinia pestis. Proc Natl Acad Sci U S A (2004) 5.04
Evolutionary history of Salmonella typhi. Science (2006) 5.00
Salmonella typhi, the causative agent of typhoid fever, is approximately 50,000 years old. Infect Genet Evol (2002) 4.96
Microbiology in the post-genomic era. Nat Rev Microbiol (2008) 4.88
Citrobacter rodentium of mice and man. Cell Microbiol (2005) 4.76
Whole-genome sequencing to identify transmission of Mycobacterium abscessus between patients with cystic fibrosis: a retrospective cohort study. Lancet (2013) 4.75
Routine use of microbial whole genome sequencing in diagnostic and public health microbiology. PLoS Pathog (2012) 4.69
IFITM3 restricts the morbidity and mortality associated with influenza. Nature (2012) 4.66
Reagent and laboratory contamination can critically impact sequence-based microbiome analyses. BMC Biol (2014) 4.39
Artemis: an integrated platform for visualization and analysis of high-throughput sequence-based experimental data. Bioinformatics (2011) 4.31
Interpolated variable order motifs for identification of horizontally acquired DNA: revisiting the Salmonella pathogenicity islands. Bioinformatics (2006) 4.27
Simultaneous assay of every Salmonella Typhi gene using one million transposon mutants. Genome Res (2009) 4.12
Emergence and global spread of epidemic healthcare-associated Clostridium difficile. Nat Genet (2012) 4.10
N-linked glycosylation in Campylobacter jejuni and its functional transfer into E. coli. Science (2002) 4.04
Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa. Lancet (2012) 4.02
Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype. Genome Res (2009) 3.99
Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans. Nat Genet (2013) 3.89
The complete genome, comparative and functional analysis of Stenotrophomonas maltophilia reveals an organism heavily shielded by drug resistance determinants. Genome Biol (2008) 3.85
Targeted restoration of the intestinal microbiota with a simple, defined bacteriotherapy resolves relapsing Clostridium difficile disease in mice. PLoS Pathog (2012) 3.81
Protein glycosylation in bacterial mucosal pathogens. Nat Rev Microbiol (2005) 3.75
Genome plasticity of BCG and impact on vaccine efficacy. Proc Natl Acad Sci U S A (2007) 3.73
Comparative genome and phenotypic analysis of Clostridium difficile 027 strains provides insight into the evolution of a hypervirulent bacterium. Genome Biol (2009) 3.66
Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens. Genome Biol (2009) 3.63
Comparative genomic analyses of seventeen Streptococcus pneumoniae strains: insights into the pneumococcal supragenome. J Bacteriol (2007) 3.62
Comparative genome analysis of Salmonella Enteritidis PT4 and Salmonella Gallinarum 287/91 provides insights into evolutionary and host adaptation pathways. Genome Res (2008) 3.54
Genome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genes. Cell (2013) 3.47
Reductive evolution and niche adaptation inferred from the genome of Mycobacterium ulcerans, the causative agent of Buruli ulcer. Genome Res (2007) 3.45
Microarrays reveal that each of the ten dominant lineages of Staphylococcus aureus has a unique combination of surface-associated and regulatory genes. J Bacteriol (2006) 3.37
Multilocus sequence typing as a replacement for serotyping in Salmonella enterica. PLoS Pathog (2012) 3.37
Comparative genomic structure of prokaryotes. Annu Rev Genet (2004) 3.34
The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081. PLoS Genet (2006) 3.33
Sequencing and analysis of the genome of the Whipple's disease bacterium Tropheryma whipplei. Lancet (2003) 3.30
Insights from the complete genome sequence of Mycobacterium marinum on the evolution of Mycobacterium tuberculosis. Genome Res (2008) 3.26
BamView: viewing mapped read alignment data in the context of the reference sequence. Bioinformatics (2010) 3.24
Shigella sonnei genome sequencing and phylogenetic analysis indicate recent global dissemination from Europe. Nat Genet (2012) 3.22
Evolutionary dynamics of Clostridium difficile over short and long time scales. Proc Natl Acad Sci U S A (2010) 3.18