PubRank

Yuji Mishina

Author PubWeight™ 198.72‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Identification of the haematopoietic stem cell niche and control of the niche size. Nature 2003 18.17
2 Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction. Proc Natl Acad Sci U S A 2003 7.87
3 BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 2004 7.37
4 BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nat Med 2008 4.20
5 Oct4/Sox2-regulated miR-302 targets cyclin D1 in human embryonic stem cells. Mol Cell Biol 2008 4.07
6 Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development 2004 3.46
7 Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. J Biol Chem 2004 3.21
8 Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc Natl Acad Sci U S A 2002 2.99
9 Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Circulation 2007 2.93
10 Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo. Proc Natl Acad Sci U S A 2005 2.82
11 Requirement of Bmpr1a for Müllerian duct regression during male sexual development. Nat Genet 2002 2.75
12 Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature 2013 2.70
13 Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. J Biol Chem 2004 2.70
14 Distinct functions for Bmp signaling in lip and palate fusion in mice. Development 2005 2.46
15 Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists. Nat Med 2011 2.40
16 BMP4-BMPR1A signaling in beta cells is required for and augments glucose-stimulated insulin secretion. Cell Metab 2007 2.39
17 BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proc Natl Acad Sci U S A 2004 2.25
18 BMP signaling and early embryonic patterning. Cytokine Growth Factor Rev 2005 2.25
19 Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia. Gastroenterology 2006 2.21
20 Histone demethylase JHDM2A is critical for Tnp1 and Prm1 transcription and spermatogenesis. Nature 2007 2.21
21 Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion. Stem Cells 2006 2.09
22 Bone morphogenetic protein signaling is essential for terminal differentiation of the intestinal secretory cell lineage. Gastroenterology 2007 2.07
23 BMP receptor signaling is required for postnatal maintenance of articular cartilage. PLoS Biol 2004 2.05
24 BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development 2004 1.93
25 BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development 2008 1.86
26 Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol 2006 1.83
27 Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann N Y Acad Sci 2004 1.80
28 Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family. Mol Cell Biol 2004 1.73
29 Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2. Genesis 2006 1.67
30 Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest. Am J Physiol Heart Circ Physiol 2009 1.66
31 BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development 2006 1.59
32 Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development 2006 1.56
33 Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes Dev 2003 1.55
34 Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. J Bone Miner Res 2010 1.54
35 Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. J Bone Miner Res 2008 1.54
36 BMP signalling inhibits premature neural differentiation in the mouse embryo. Development 2007 1.49
37 BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron 2002 1.49
38 Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circ Res 2005 1.48
39 BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. J Cell Sci 2011 1.44
40 Positional cloning of the gene LIMBIN responsible for bovine chondrodysplastic dwarfism. Proc Natl Acad Sci U S A 2002 1.42
41 Regulation of outgrowth and apoptosis for the terminal appendage: external genitalia development by concerted actions of BMP signaling [corrected]. Development 2003 1.38
42 Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development 2011 1.37
43 Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. Dev Biol 2006 1.37
44 BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development 2007 1.35
45 FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate. Development 2009 1.35
46 Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development 2005 1.33
47 The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation. Dev Biol 2009 1.25
48 BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. J Neurosci 2010 1.22
49 BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning. Dev Biol 2006 1.20
50 Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development 2004 1.18
51 BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning. Dev Biol 2004 1.18
52 BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice. Development 2004 1.18
53 BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex. J Neurosci 2007 1.16
54 BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways. Development 2009 1.15
55 BMP receptor ALK3 controls collecting system development. J Am Soc Nephrol 2008 1.14
56 Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Dev Biol 2008 1.13
57 Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. Am J Pathol 2008 1.13
58 Optimized beta-galactosidase staining method for simultaneous detection of endogenous gene expression in early mouse embryos. Genesis 2006 1.10
59 Gastroduodenal mucosal injury in patients taking low-dose aspirin and the role of gastric mucoprotective drugs: possible effect of rebamipide. J Clin Biochem Nutr 2010 1.10
60 Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis. Nat Genet 2003 1.08
61 Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators. Proc Natl Acad Sci U S A 2011 1.08
62 Genetic studies of the AMH/MIS signaling pathway for Müllerian duct regression. Mol Cell Endocrinol 2003 1.07
63 BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo. Dev Biol 2004 1.06
64 Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol 2010 1.06
65 Smooth muscle protein 22alpha-mediated patchy deletion of Bmpr1a impairs cardiac contractility but protects against pulmonary vascular remodeling. Circ Res 2007 1.06
66 TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling. J Biol Chem 2008 1.06
67 Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein. Mol Cell Biol 2005 1.04
68 Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations. Dis Model Mech 2010 1.04
69 Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice. J Bone Miner Res 2013 1.01
70 Deficient Alk3-mediated BMP signaling causes prenatal omphalocele-like defect. Biochem Biophys Res Commun 2007 0.99
71 BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis. Dev Dyn 2007 0.99
72 BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites. Development 2006 0.98
73 Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice. J Bone Miner Res 2011 0.98
74 Developmental expression and function of Bmp4 in spermatogenesis and in maintaining epididymal integrity. Dev Biol 2004 0.97
75 Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Dev Biol 2010 0.97
76 Constitutively active ALK2 receptor mutants require type II receptor cooperation. Mol Cell Biol 2013 0.96
77 Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development. Genesis 2009 0.96
78 Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species. Proc Natl Acad Sci U S A 2012 0.95
79 Generation of a conditional mutant allele for Tab1 in mouse. Genesis 2008 0.93
80 TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration. Blood 2012 0.93
81 Prevalence of erosive esophagitis among Japanese patients taking low-dose aspirin. J Gastroenterol Hepatol 2010 0.93
82 A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response. Nat Commun 2012 0.92
83 Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm. Development 2011 0.92
84 Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells. J Cell Sci 2013 0.92
85 c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression. Nat Cell Biol 2012 0.92
86 New insights on the roles of BMP signaling in bone-A review of recent mouse genetic studies. Biofactors 2011 0.91
87 SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development 2008 0.91
88 Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn 2010 0.90
89 BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies. Int J Dev Biol 2002 0.90
90 Generation of a conditional null allele for Dmp1 in mouse. Genesis 2008 0.89
91 Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium. J Biol Chem 2013 0.89
92 Bmp2 is required for cephalic neural tube closure in the mouse. Dev Dyn 2009 0.89
93 Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells. Am J Physiol Gastrointest Liver Physiol 2011 0.89
94 In situ hybridization methods for mouse whole mounts and tissue sections with and without additional β-galactosidase staining. Methods Mol Biol 2014 0.89
95 BMP signaling through BMPRIA in astrocytes is essential for proper cerebral angiogenesis and formation of the blood-brain-barrier. Mol Cell Neurosci 2008 0.88
96 Whole-embryo culture of E5.5 mouse embryos: development to the gastrulation stage. Genesis 2003 0.88
97 Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry. Development 2011 0.88
98 Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1. Biochem Biophys Res Commun 2011 0.88
99 BMP receptor 1A determines the cell fate of the postnatal growth plate. Int J Biol Sci 2013 0.87
100 Potential contribution of neural crest cells to dental enamel formation. Biochem Biophys Res Commun 2011 0.87
101 TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells. J Biol Chem 2013 0.87
102 Osterix-Cre transgene causes craniofacial bone development defect. Calcif Tissue Int 2014 0.86
103 Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling. Genesis 2009 0.86
104 Neural crest contribution to lingual mesenchyme, epithelium and developing taste papillae and taste buds. Dev Biol 2012 0.86
105 Establishment of left-right asymmetry in vertebrate development: the node in mouse embryos. Cell Mol Life Sci 2013 0.85
106 Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryo. Dev Biol 2010 0.85
107 Genetic studies of MIS signalling in sexual development. Novartis Found Symp 2002 0.84
108 Genetically modified bone morphogenetic protein signalling alters traumatic brain injury-induced gene expression responses in the adult mouse. J Neurosci Res 2006 0.84
109 Identification and characterization of neural crest-derived cells in adult periodontal ligament of mice. Arch Oral Biol 2012 0.84
110 Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol 2011 0.83
111 Mechanisms of bone morphogenetic protein 2 (BMP2) stimulated inhibitor of DNA binding 3 (Id3) transcription. Mol Cell Endocrinol 2010 0.83
112 Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton. J Biol Chem 2010 0.82
113 Cranial neural crest cell contribution to craniofacial formation, pathology, and future directions in tissue engineering. Birth Defects Res C Embryo Today 2014 0.81
114 Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina. Mol Cell Neurosci 2012 0.81
115 The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth. Nat Commun 2013 0.81
116 Critical role of Bmpr1a in mandibular condyle growth. Connect Tissue Res 2014 0.81
117 AF-2 knock-in mutation of estrogen receptor alpha: Cre-loxP excision of a PGK-neo cassette from the 3' UTR. Genesis 2002 0.80
118 TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. PLoS One 2012 0.80
119 Sox8 and Sertoli-cell function. Ann N Y Acad Sci 2007 0.80
120 Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of SMADS and TAK1 in early mouse embryo. Dev Dyn 2011 0.79
121 Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling. J Neurosci 2013 0.79
122 SOX8 regulates permeability of the blood-testes barrier that affects adult male fertility in the mouse. Biol Reprod 2013 0.77
123 Receptor knock-out and gene targeting. Generation of knock-out mice. Methods Mol Med 2003 0.76
124 The DVE changes distal epiblast fate from definitive endoderm to neurectoderm by antagonizing nodal signaling. Dev Dyn 2007 0.76
125 Abstract 148: use of bmp type I alk-3 knockout mice to develop novel treatment strategies for trauma-induced heterotopic ossification. Plast Reconstr Surg 2014 0.75
126 Abstract 89: Novel Targeting of the Alk-2 Receptor Using the Cre/lox System to Enhance Osseous Regeneration by Mesenchymal Stem Cells. Plast Reconstr Surg 2014 0.75
127 Thienopyridine and cilostazol are safer for gastroduodenal mucosa than low-dose aspirin--second report of endoscopic evaluation. Thromb Res 2009 0.75