Published in J Neurosci on January 26, 2005
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Afferent neurotransmission mediated by hemichannels in mammalian taste cells. EMBO J (2007) 2.51
Separate populations of receptor cells and presynaptic cells in mouse taste buds. J Neurosci (2006) 2.46
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Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste. J Physiol (2008) 1.86
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Action potential-enhanced ATP release from taste cells through hemichannels. J Neurophysiol (2010) 1.13
Adenosine enhances sweet taste through A2B receptors in the taste bud. J Neurosci (2012) 1.10
GABA expression in the mammalian taste bud functions as a route of inhibitory cell-to-cell communication. Proc Natl Acad Sci U S A (2009) 1.08
Functional expression of ionotropic purinergic receptors on mouse taste bud cells. J Physiol (2007) 1.06
GABA, its receptors, and GABAergic inhibition in mouse taste buds. J Neurosci (2011) 1.05
Capacitance measurements of regulated exocytosis in mouse taste cells. J Neurosci (2010) 1.04
Knocking out P2X receptors reduces transmitter secretion in taste buds. J Neurosci (2011) 1.03
Transsynaptic transport of wheat germ agglutinin expressed in a subset of type II taste cells of transgenic mice. BMC Neurosci (2008) 1.00
Qualitative and quantitative differences between taste buds of the rat and mouse. BMC Neurosci (2007) 1.00
Evidence for a role of glutamate as an efferent transmitter in taste buds. BMC Neurosci (2010) 0.95
Acid stimulation (sour taste) elicits GABA and serotonin release from mouse taste cells. PLoS One (2011) 0.95
Postsynaptic P2X3-containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice. J Physiol (2015) 0.92
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Interaction between the second messengers cAMP and Ca2+ in mouse presynaptic taste cells. J Physiol (2009) 0.91
Mechanisms of taste bud cell loss after head and neck irradiation. J Neurosci (2012) 0.89
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Expression of GABAergic receptors in mouse taste receptor cells. PLoS One (2010) 0.88
Synaptic communication and signal processing among sensory cells in taste buds. J Physiol (2014) 0.87
Using biosensors to detect the release of serotonin from taste buds during taste stimulation. Arch Ital Biol (2005) 0.87
Taste bud cells of adult mice are responsive to Wnt/β-catenin signaling: implications for the renewal of mature taste cells. Genesis (2011) 0.87
Glutamate may be an efferent transmitter that elicits inhibition in mouse taste buds. PLoS One (2012) 0.86
Acetylcholine is released from taste cells, enhancing taste signalling. J Physiol (2012) 0.85
Characterization of the expression pattern of adrenergic receptors in rat taste buds. Neuroscience (2010) 0.84
Real-time detection of acetylcholine release from the human endocrine pancreas. Nat Protoc (2012) 0.83
Inborn mechanisms of food preference and avoidance: the role of polymorphisms in neuromodulatory systems. Front Mol Neurosci (2013) 0.83
Kokumi substances, enhancers of basic tastes, induce responses in calcium-sensing receptor expressing taste cells. PLoS One (2012) 0.82
Immunocytochemical analysis of P2X2 in rat circumvallate taste buds. BMC Neurosci (2012) 0.82
Expression of Six1 and Six4 in mouse taste buds. J Mol Histol (2010) 0.81
Synaptophysin as a probable component of neurotransmission occurring in taste receptor cells. J Mol Histol (2009) 0.81
The sweet taste quality is linked to a cluster of taste fibers in primates: lactisole diminishes preference and responses to sweet in S fibers (sweet best) chorda tympani fibers of M. fascicularis monkey. BMC Physiol (2009) 0.81
A physiologic role for serotonergic transmission in adult rat taste buds. PLoS One (2014) 0.80
Leptin's effect on taste bud calcium responses and transmitter secretion. Chem Senses (2014) 0.80
Orosensory and Homeostatic Functions of the Insular Taste Cortex. Chemosens Percept (2012) 0.80
L-Amino Acids Elicit Diverse Response Patterns in Taste Sensory Cells: A Role for Multiple Receptors. PLoS One (2015) 0.79
Neuronal functional diversity and collective behaviors. J Biol Phys (2008) 0.79
Context-dependent fluctuation of serotonin in the auditory midbrain: the influence of sex, reproductive state and experience. J Exp Biol (2013) 0.79
Immunohistochemical localization of aromatic L-amino acid decarboxylase in mouse taste buds and developing taste papillae. Histochem Cell Biol (2007) 0.79
Accelerated turnover of taste bud cells in mice deficient for the cyclin-dependent kinase inhibitor p27Kip1. BMC Neurosci (2011) 0.79
The Role of 5-HT3 Receptors in Signaling from Taste Buds to Nerves. J Neurosci (2015) 0.78
Sarco/Endoplasmic reticulum Ca2+-ATPases (SERCA) contribute to GPCR-mediated taste perception. PLoS One (2011) 0.78
Expression of adenosine A2b receptor in rat type II and III taste cells. Histochem Cell Biol (2013) 0.78
Ryanodine Receptors Selectively Interact with L Type Calcium Channels in Mouse Taste Cells. PLoS One (2013) 0.78
Investigating the motivational mechanism of altered saline consumption following 5-HT(1A) manipulation. Behav Neurosci (2008) 0.77
Tachykinins stimulate a subset of mouse taste cells. PLoS One (2012) 0.77
Type II and III Taste Bud Cells Preferentially Expressed Kainate Glutamate Receptors in Rats. Korean J Physiol Pharmacol (2009) 0.77
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Molecular mechanisms of taste recognition: considerations about the role of saliva. Int J Mol Sci (2015) 0.75
Processing umami and other tastes in mammalian taste buds. Ann N Y Acad Sci (2009) 0.75
The effect of imiquimod on taste bud calcium transients and transmitter secretion. Br J Pharmacol (2016) 0.75
Cocaine decreases saccharin preference without altering sweet taste sensitivity. Pharmacol Biochem Behav (2015) 0.75
Non-conventional features of peripheral serotonin signalling - the gut and beyond. Nat Rev Gastroenterol Hepatol (2017) 0.75
High bone density due to a mutation in LDL-receptor-related protein 5. N Engl J Med (2002) 11.28
Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways. Cell (2003) 5.95
Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling. J Biol Chem (2005) 5.33
Regulation of PTEN by Rho small GTPases. Nat Cell Biol (2005) 4.51
The role of pannexin 1 hemichannels in ATP release and cell-cell communication in mouse taste buds. Proc Natl Acad Sci U S A (2007) 4.01
Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42. Cell (2003) 3.66
Direct binding of the PDZ domain of Dishevelled to a conserved internal sequence in the C-terminal region of Frizzled. Mol Cell (2003) 3.06
Differential targeting of Gbetagamma-subunit signaling with small molecules. Science (2006) 2.96
The cell biology of taste. J Cell Biol (2010) 2.78
Exploration and grading of possible genes from 183 bacterial strains by a common protocol to identification of new genes: Gene Trek in Prokaryote Space (GTPS). DNA Res (2006) 2.51
Separate populations of receptor cells and presynaptic cells in mouse taste buds. J Neurosci (2006) 2.46
Dkk2 has a role in terminal osteoblast differentiation and mineralized matrix formation. Nat Genet (2005) 2.10
Synaptotagmin-mediated vesicle fusion regulates cell migration. Nat Immunol (2010) 2.09
Breadth of tuning and taste coding in mammalian taste buds. J Neurosci (2007) 2.06
ATP release through connexin hemichannels and gap junction transfer of second messengers propagate Ca2+ signals across the inner ear. Proc Natl Acad Sci U S A (2008) 2.01
Sites of regulated phosphorylation that control K-Cl cotransporter activity. Cell (2009) 1.93
Presynaptic (Type III) cells in mouse taste buds sense sour (acid) taste. J Physiol (2008) 1.86
Regulation of Chk1 includes chromatin association and 14-3-3 binding following phosphorylation on Ser-345. J Biol Chem (2003) 1.82
Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science (2008) 1.81
Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5. Cancer Cell (2009) 1.78
The LRP5 high-bone-mass G171V mutation disrupts LRP5 interaction with Mesd. Mol Cell Biol (2004) 1.77
P-Rex1 is a primary Rac2 guanine nucleotide exchange factor in mouse neutrophils. Curr Biol (2005) 1.70
PTEN as an effector in the signaling of antimigratory G protein-coupled receptor. Proc Natl Acad Sci U S A (2005) 1.67
Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. J Neurosci (2009) 1.64
Alpha cells secrete acetylcholine as a non-neuronal paracrine signal priming beta cell function in humans. Nat Med (2011) 1.62
Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis. Proc Natl Acad Sci U S A (2002) 1.60
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1. J Biol Chem (2002) 1.60
Second cysteine-rich domain of Dickkopf-2 activates canonical Wnt signaling pathway via LRP-6 independently of dishevelled. J Biol Chem (2001) 1.57
Evidence for direct activation of mTORC2 kinase activity by phosphatidylinositol 3,4,5-trisphosphate. J Biol Chem (2011) 1.56
Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum. J Neurosci (2005) 1.56
Epithelial inducible nitric oxide synthase causes bacterial translocation by impairment of enterocytic tight junctions via intracellular signals of Rho-associated kinase and protein kinase C zeta. Crit Care Med (2011) 1.56
Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction. Mol Cell Biol (2006) 1.48
Inhibition of receptor-localized PI3K preserves cardiac beta-adrenergic receptor function and ameliorates pressure overload heart failure. J Clin Invest (2003) 1.47
A possible cellular mechanism of neuronal loss in the dorsal root ganglia of Dystonia musculorum (dt) mice. J Neuropathol Exp Neurol (2006) 1.46
Cell-to-cell communication in intact taste buds through ATP signalling from pannexin 1 gap junction hemichannels. J Physiol (2009) 1.44
DNA-PKcs, but not TLR9, is required for activation of Akt by CpG-DNA. EMBO J (2005) 1.44
PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. Proc Natl Acad Sci U S A (2004) 1.42
Acid-sensitive two-pore domain potassium (K2P) channels in mouse taste buds. J Neurophysiol (2004) 1.41
Characterization of the Kremen-binding site on Dkk1 and elucidation of the role of Kremen in Dkk-mediated Wnt antagonism. J Biol Chem (2008) 1.35
Umami responses in mouse taste cells indicate more than one receptor. J Neurosci (2006) 1.33
Individual mouse taste cells respond to multiple chemical stimuli. J Physiol (2002) 1.31
Characterization and application of a new optical probe for membrane lipid domains. Biophys J (2006) 1.31
The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol (2008) 1.31
Norepinephrine is coreleased with serotonin in mouse taste buds. J Neurosci (2008) 1.29
Multiple mechanisms for Wnt11-mediated repression of the canonical Wnt signaling pathway. J Biol Chem (2004) 1.27
Faithful expression of GFP from the PLCbeta2 promoter in a functional class of taste receptor cells. Chem Senses (2006) 1.24
Intracellular Ca(2+) and TRPM5-mediated membrane depolarization produce ATP secretion from taste receptor cells. J Physiol (2010) 1.24
Transcriptional analysis of genes for energy catabolism and hydrolytic enzymes in the filamentous fungus Aspergillus oryzae using cDNA microarrays and expressed sequence tags. Appl Microbiol Biotechnol (2004) 1.24
Phospholipase cbeta is critical for T cell chemotaxis. J Immunol (2007) 1.22
Modulation of cell adhesion and motility in the immune system by Myo1f. Science (2006) 1.22
Deletion of the phosphoinositide 3-kinase p110gamma gene attenuates murine atherosclerosis. Proc Natl Acad Sci U S A (2007) 1.20
Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway. Proc Natl Acad Sci U S A (2013) 1.19
Acid-sensing ion channel-2 is not necessary for sour taste in mice. J Neurosci (2004) 1.19
Characterization of function of three domains in dishevelled-1: DEP domain is responsible for membrane translocation of dishevelled-1. Cell Res (2004) 1.19
Signaling requirements for translocation of P-Rex1, a key Rac2 exchange factor involved in chemoattractant-stimulated human neutrophil function. J Leukoc Biol (2007) 1.17
Role of the G-protein subunit alpha-gustducin in taste cell responses to bitter stimuli. J Neurosci (2003) 1.17
Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells. Mol Biol Cell (2005) 1.17
Structural insight into the mechanisms of Wnt signaling antagonism by Dkk. J Biol Chem (2008) 1.16
Cell stimulation with optically manipulated microsources. Nat Methods (2009) 1.15
Taste receptors for umami: the case for multiple receptors. Am J Clin Nutr (2009) 1.14
Integrin-induced PIP5K1C kinase polarization regulates neutrophil polarization, directionality, and in vivo infiltration. Immunity (2010) 1.10
A PLCβ/PI3Kγ-GSK3 signaling pathway regulates cofilin phosphatase slingshot2 and neutrophil polarization and chemotaxis. Dev Cell (2011) 1.10
Adenosine enhances sweet taste through A2B receptors in the taste bud. J Neurosci (2012) 1.10
The relative role of PLCbeta and PI3Kgamma in platelet activation. Blood (2005) 1.09
Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice. J Clin Invest (2008) 1.09
PRR5L degradation promotes mTORC2-mediated PKC-δ phosphorylation and cell migration downstream of Gα12. Nat Cell Biol (2012) 1.08
Identification of transmembrane protein 88 (TMEM88) as a dishevelled-binding protein. J Biol Chem (2010) 1.06
IgE- and IgE+Ag-mediated mast cell migration in an autocrine/paracrine fashion. Blood (2005) 1.06
GABA, its receptors, and GABAergic inhibition in mouse taste buds. J Neurosci (2011) 1.05
Involvement of the calcium-sensing receptor in human taste perception. J Biol Chem (2009) 1.04
Regulatory interactions between the checkpoint kinase Chk1 and the proteins of the DNA-dependent protein kinase complex. J Biol Chem (2003) 1.04
Knocking out P2X receptors reduces transmitter secretion in taste buds. J Neurosci (2011) 1.03
Role of guanine nucleotide exchange factor P-Rex-2b in sphingosine 1-phosphate-induced Rac1 activation and cell migration in endothelial cells. Prostaglandins Other Lipid Mediat (2005) 1.02
PLCbeta2-independent behavioral avoidance of prototypical bitter-tasting ligands. Chem Senses (2005) 1.01
Regulation of phosphatidylinositol kinases and metabolism by Wnt3a and Dvl. J Biol Chem (2009) 1.01
Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils. J Biol Chem (2010) 1.00
Activation of polycystic kidney disease-2-like 1 (PKD2L1)-PKD1L3 complex by acid in mouse taste cells. J Biol Chem (2010) 1.00
SRF is required for neutrophil migration in response to inflammation. Blood (2014) 0.99
GBP binds kinesin light chain and translocates during cortical rotation in Xenopus eggs. Development (2003) 0.99
Beta-catenin regulates myogenesis by relieving I-mfa-mediated suppression of myogenic regulatory factors in P19 cells. Proc Natl Acad Sci U S A (2005) 0.98
Tastants evoke cAMP signal in taste buds that is independent of calcium signaling. Am J Physiol Cell Physiol (2006) 0.97
Suppression of PLCbeta2 by endotoxin plays a role in the adenosine A(2A) receptor-mediated switch of macrophages from an inflammatory to an angiogenic phenotype. Am J Pathol (2009) 0.96
Acid stimulation (sour taste) elicits GABA and serotonin release from mouse taste cells. PLoS One (2011) 0.95
Family size in white gay and heterosexual men. Arch Sex Behav (2005) 0.94
Involvement of endoplasmic reticulum stress and activation of MAP kinases in beta-lapachone-induced human prostate cancer cell apoptosis. Histol Histopathol (2008) 0.94
Mitogen- and ultraviolet-B-induced signaling pathways in normal human melanocytes. J Invest Dermatol (2002) 0.94
The structural basis of DKK-mediated inhibition of Wnt/LRP signaling. Sci Signal (2012) 0.94
A requirement of MAPKAPK2 in the uropod localization of PTEN during FMLP-induced neutrophil chemotaxis. Biochem Biophys Res Commun (2004) 0.93