Published in Int Immunol on January 31, 2005
The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 9.18
PD-L1 negatively regulates CD4+CD25+Foxp3+ Tregs by limiting STAT-5 phosphorylation in patients chronically infected with HCV. J Clin Invest (2009) 2.26
Single-cell quantification of IL-2 response by effector and regulatory T cells reveals critical plasticity in immune response. Mol Syst Biol (2010) 2.21
'Yin-Yang' functions of transforming growth factor-beta and T regulatory cells in immune regulation. Immunol Rev (2007) 1.98
Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice. J Immunol (2007) 1.78
Competing feedback loops shape IL-2 signaling between helper and regulatory T lymphocytes in cellular microenvironments. Proc Natl Acad Sci U S A (2010) 1.71
T-cell tolerance and the multi-functional role of IL-2R signaling in T-regulatory cells. Immunol Rev (2011) 1.69
Negative feedback control of the autoimmune response through antigen-induced differentiation of IL-10-secreting Th1 cells. J Exp Med (2009) 1.66
Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target. Immunology (2008) 1.59
Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2. J Exp Med (2013) 1.53
TGF-beta and regulatory T cell in immunity and autoimmunity. J Clin Immunol (2008) 1.49
Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease. Crit Rev Immunol (2012) 1.49
Rapid regulatory T-cell response prevents cytokine storm in CD28 superagonist treated mice. PLoS One (2009) 1.44
Interleukin-2-dependent mechanisms of tolerance and immunity in vivo. J Immunol (2006) 1.43
Development of regulatory T cells requires IL-7Ralpha stimulation by IL-7 or TSLP. Blood (2008) 1.43
Molecular mechanisms of treg-mediated T cell suppression. Front Immunol (2012) 1.41
Tim-3 pathway controls regulatory and effector T cell balance during hepatitis C virus infection. J Immunol (2012) 1.29
CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta. J Immunol (2009) 1.28
Competition for IL-2 between Regulatory and Effector T Cells to Chisel Immune Responses. Front Immunol (2012) 1.14
Regulatory T cells overturned: the effectors fight back. Immunology (2009) 1.13
The power and the promise of restimulation-induced cell death in human immune diseases. Immunol Rev (2010) 1.09
Regulatory T cells: immune suppression and beyond. Cell Mol Immunol (2010) 1.09
IL-21 restricts virus-driven Treg cell expansion in chronic LCMV infection. PLoS Pathog (2013) 1.03
Superagonistic anti-CD28 antibodies: potent activators of regulatory T cells for the therapy of autoimmune diseases. Ann Rheum Dis (2005) 0.98
An essential role for the IL-2 receptor in Treg cell function. Nat Immunol (2016) 0.97
Impact of alemtuzumab treatment on the survival and function of human regulatory T cells in vitro. Immunology (2014) 0.96
Regulatory T cells require TCR signaling for their suppressive function. J Immunol (2015) 0.95
T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't. J Leukoc Biol (2008) 0.93
Thymic regulatory T cell niche size is dictated by limiting IL-2 from antigen-bearing dendritic cells and feedback competition. Nat Immunol (2015) 0.92
Increased CD8+ T-cell function following castration and immunization is countered by parallel expansion of regulatory T cells. Cancer Res (2012) 0.91
Homeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic Tregs. Immunol Rev (2014) 0.89
The ambiguity in immunology. Front Immunol (2012) 0.87
Large-scale expansion of rat CD4+ CD25+ T(reg) cells in the absence of T-cell receptor stimulation. Immunology (2006) 0.87
MicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and development. Crit Rev Immunol (2013) 0.87
Mathematical Models of the Impact of IL2 Modulation Therapies on T Cell Dynamics. Front Immunol (2013) 0.81
Expansion of CD4+CD25+ suppressive regulatory T cells from rhesus macaque peripheral blood by FN18/antihuman CD28-coated Dynal beads. Hum Immunol (2007) 0.81
NK cells and their ability to modulate T cells during virus infections. Crit Rev Immunol (2014) 0.80
Natural and induced regulatory T cells: targets for immunotherapy of autoimmune disease and allergy. Inflamm Allergy Drug Targets (2006) 0.80
Sequential induction of effector function, tissue migration and cell death during polyclonal activation of mouse regulatory T-cells. PLoS One (2012) 0.79
Transplantation tolerance: Clinical potential of regulatory T cells. Self Nonself (2011) 0.79
Chronically HIV-1 Infected Patients Exhibit Low Frequencies of CD25+ Regulatory T Cells. Open Virol J (2012) 0.78
In vivo suppression of naive CD4 T cell responses by IL-2- and antigen-stimulated T lymphocytes in the absence of APC competition. J Immunol (2008) 0.77
Interleukin-7 optimizes FOXP3+CD4+ regulatory T cells reactivity to interleukin-2 by modulating CD25 expression. PLoS One (2014) 0.76
Fasciola hepatica reinfection potentiates a mixed Th1/Th2/Th17/Treg response and correlates with the clinical phenotypes of anemia. PLoS One (2017) 0.75
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity (2006) 29.29
An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature (2010) 10.37
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature (2008) 10.15
The regulation of IL-10 production by immune cells. Nat Rev Immunol (2010) 9.18
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol (2008) 6.76
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity (2009) 6.05
Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol (2011) 5.98
In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines. J Exp Med (2002) 5.28
Differentiation and function of Th17 T cells. Curr Opin Immunol (2007) 5.14
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest (2009) 4.74
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. Nat Immunol (2006) 4.44
Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells. PLoS Biol (2005) 4.01
The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J Exp Med (2002) 3.91
Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell (2011) 3.80
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J Exp Med (2008) 3.50
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol (2004) 3.46
Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med (2003) 3.41
Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol (2010) 3.12
Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. J Clin Invest (2005) 2.94
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat Immunol (2011) 2.69
Interleukin-10 production by Th1 cells requires interleukin-12-induced STAT4 transcription factor and ERK MAP kinase activation by high antigen dose. Immunity (2009) 2.61
Th17 T cells: linking innate and adaptive immunity. Semin Immunol (2007) 2.54
Type I interferon dependence of plasmacytoid dendritic cell activation and migration. J Exp Med (2005) 2.53
Impairment of immunological memory in the absence of MHC despite survival of memory T cells. Nat Immunol (2002) 2.42
Further checkpoints in Th1 development. Immunity (2002) 2.31
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody. J Exp Med (2002) 2.25
Interleukin-17-producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers. Arthritis Rheum (2008) 2.25
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses. Nat Immunol (2013) 2.24
SOCS-3 regulates onset and maintenance of T(H)2-mediated allergic responses. Nat Med (2003) 2.20
The aryl hydrocarbon receptor in immunity. Trends Immunol (2009) 2.19
T cell regulation as a side effect of homeostasis and competition. J Exp Med (2003) 2.15
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals. J Immunol (2006) 2.11
A restricted subset of dendritic cells captures airborne antigens and remains able to activate specific T cells long after antigen exposure. Immunity (2002) 2.09
Neutrophils in tuberculosis: friend or foe? Trends Immunol (2011) 1.94
Transcriptional blood signatures distinguish pulmonary tuberculosis, pulmonary sarcoidosis, pneumonias and lung cancers. PLoS One (2013) 1.86
Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung. Eur J Immunol (2010) 1.84
IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med (2013) 1.75
The functional plasticity of T cell subsets. Nat Rev Immunol (2009) 1.74
Tripartite-motif proteins and innate immune regulation. Curr Opin Immunol (2010) 1.73
Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells. J Exp Med (2003) 1.71
From IL-2 to IL-37: the expanding spectrum of anti-inflammatory cytokines. Nat Immunol (2012) 1.70
Detectable changes in the blood transcriptome are present after two weeks of antituberculosis therapy. PLoS One (2012) 1.68
Type I interferon-dependent and -independent expression of tripartite motif proteins in immune cells. Eur J Immunol (2008) 1.67
GATA-3 directly remodels the IL-10 locus independently of IL-4 in CD4+ T cells. J Immunol (2006) 1.59
The resolution of inflammation. Nat Rev Immunol (2012) 1.58
TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells. J Exp Med (2009) 1.58
Role of T cells in innate and adaptive immunity against murine Burkholderia pseudomallei infection. J Infect Dis (2005) 1.56
IL-27 promotes IL-10 production by effector Th1 CD4+ T cells: a critical mechanism for protection from severe immunopathology during malaria infection. J Immunol (2011) 1.56
TPL2-mediated activation of ERK1 and ERK2 regulates the processing of pre-TNF alpha in LPS-stimulated macrophages. J Cell Sci (2008) 1.52
Targeting self- and foreign antigens to dendritic cells via DC-ASGPR generates IL-10-producing suppressive CD4+ T cells. J Exp Med (2012) 1.50
Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells. J Exp Med (2006) 1.49
Breakpoints in immunoregulation required for Th1 cells to induce diabetes. Eur J Immunol (2006) 1.48
TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells. Trends Immunol (2006) 1.46
Integrated T-cell receptor and costimulatory signals determine TGF-β-dependent differentiation and maintenance of Foxp3+ regulatory T cells. Eur J Immunol (2011) 1.45
External influences on the immune system via activation of the aryl hydrocarbon receptor. Semin Immunol (2011) 1.41
Identification of a macrophage-specific chromatin signature in the IL-10 locus. J Immunol (2005) 1.37
Ablation of thymic export causes accelerated decay of naive CD4 T cells in the periphery because of activation by environmental antigen. Proc Natl Acad Sci U S A (2008) 1.32
Modulation of dendritic cell function by naive and regulatory CD4+ T cells. J Immunol (2006) 1.31
ABIN-2 is required for optimal activation of Erk MAP kinase in innate immune responses. Nat Immunol (2006) 1.31
Differentiation of human T(H)-17 cells does require TGF-beta! Nat Immunol (2008) 1.27
The role of 1α,25-dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+ and IL-10+ CD4+ T cells. Eur J Immunol (2012) 1.27
Twenty-first century Foxp3. Nat Immunol (2003) 1.25
IL-10 regulates viral lung immunopathology during acute respiratory syncytial virus infection in mice. PLoS One (2012) 1.23
Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo. PLoS One (2013) 1.21
A major role for memory CD4 T cells in the control of lymphopenia-induced proliferation of naive CD4 T cells. J Immunol (2005) 1.17
The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis. Ann Rheum Dis (2012) 1.16
Influenza A virus impairs control of Mycobacterium tuberculosis coinfection through a type I interferon receptor-dependent pathway. J Infect Dis (2013) 1.16
Persistence of skin-resident memory T cells within an epidermal niche. Proc Natl Acad Sci U S A (2014) 1.14
Regulation and function of innate and adaptive interleukin-17-producing cells. EMBO Rep (2012) 1.14
The many lives of IL-9: a question of survival? Nat Immunol (2012) 1.11
Development, regulation and functional capacities of Th17 cells. Semin Immunopathol (2010) 1.10
The regulation of IL-10 expression. Curr Top Microbiol Immunol (2014) 1.09
CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40. J Exp Med (2006) 1.07
Highlights of 10 years of immunology in Nature Reviews Immunology. Nat Rev Immunol (2011) 1.06
The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis. Philos Trans R Soc Lond B Biol Sci (2014) 1.06
T helper cell differentiation more than just cytokines. Adv Immunol (2011) 1.04
Cross presentation of antigen on MHC class II via the draining lymph node after corneal transplantation in mice. J Immunol (2008) 1.04
Systems biology approaches reveal a specific interferon-inducible signature in HTLV-1 associated myelopathy. PLoS Pathog (2012) 1.03
Are dendritic cells afraid of commitment? Nat Immunol (2004) 1.02
Vaccination against tuberculosis: how can we better BCG? Microb Pathog (2012) 1.02
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis. Ann Rheum Dis (2011) 1.00
Antibody negative coeliac disease presenting in elderly people--an easily missed diagnosis. BMJ (2005) 1.00
Identification of early gene expression changes during human Th17 cell differentiation. Blood (2012) 0.99
Critical role of type 1 cytokines in controlling initial infection with Burkholderia mallei. Infect Immun (2006) 0.99
T cell homeostasis in steady state and lymphopenic conditions. Immunol Lett (2006) 0.99