Published in J Immunol on May 01, 2005
Gene transfer in humans using a conditionally replicating lentiviral vector. Proc Natl Acad Sci U S A (2006) 4.23
Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat Immunol (2009) 1.98
Homeostasis and effector function of lymphopenia-induced "memory-like" T cells in constitutively T cell-depleted mice. J Immunol (2008) 1.91
Transient and persistent effects of IL-15 on lymphocyte homeostasis in nonhuman primates. Blood (2010) 1.41
Role of naive-derived T memory stem cells in T-cell reconstitution following allogeneic transplantation. Blood (2015) 1.33
Differential lymphopenia-induced homeostatic proliferation for CD4+ and CD8+ T cells following septic injury. J Leukoc Biol (2008) 0.99
IL-15 but not IL-2 rapidly induces lethal xenogeneic graft-versus-host disease. Blood (2005) 0.97
Integration of B cells and CD8+ T in the protective regulation of systemic epithelial inflammation. Clin Immunol (2008) 0.86
IFNγ and IL-12 Restrict Th2 Responses during Helminth/Plasmodium Co-Infection and Promote IFNγ from Th2 Cells. PLoS Pathog (2015) 0.85
The influence of CD4 T-cell subsets on control of CD4 T-cell-mediated graft-versus-host disease. Immunology (2008) 0.80
Co-transplantation of pure blood stem cells with antigen-specific but not bulk T cells augments functional immunity. Proc Natl Acad Sci U S A (2012) 0.78
Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice. PLoS One (2014) 0.77
Hoxb4 overexpression in CD4 memory phenotype T cells increases the central memory population upon homeostatic proliferation. PLoS One (2013) 0.76
TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity (2006) 29.29
The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins. Nature (2008) 10.15
Onset and progression in inherited ALS determined by motor neurons and microglia. Science (2006) 9.42
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol (2008) 6.76
Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals. Immunity (2009) 6.05
Fate mapping of IL-17-producing T cells in inflammatory responses. Nat Immunol (2011) 5.98
Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J Clin Invest (2009) 4.74
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. Nat Immunol (2006) 4.44
Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells. J Exp Med (2008) 3.50
IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells. J Immunol (2004) 3.46
Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol (2010) 3.12
An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation. Nat Immunol (2011) 2.69
Impairment of immunological memory in the absence of MHC despite survival of memory T cells. Nat Immunol (2002) 2.42
Plasticity of Th17 cells in Peyer's patches is responsible for the induction of T cell-dependent IgA responses. Nat Immunol (2013) 2.24
The aryl hydrocarbon receptor in immunity. Trends Immunol (2009) 2.19
T cell regulation as a side effect of homeostasis and competition. J Exp Med (2003) 2.15
CD4+ memory T cells: functional differentiation and homeostasis. Immunol Rev (2006) 1.84
Resurrection of endogenous retroviruses in antibody-deficient mice. Nature (2012) 1.81
IL-9-mediated survival of type 2 innate lymphoid cells promotes damage control in helminth-induced lung inflammation. J Exp Med (2013) 1.75
The functional plasticity of T cell subsets. Nat Rev Immunol (2009) 1.74
Involvement of avidity for major histocompatibility complex in homeostasis of naive and memory T cells. J Exp Med (2003) 1.71
The resolution of inflammation. Nat Rev Immunol (2012) 1.58
TGFbeta1, a "Jack of all trades": the link with pro-inflammatory IL-17-producing T cells. Trends Immunol (2006) 1.46
CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production. Int Immunol (2005) 1.40
Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis. J Immunol (2005) 1.34
Ablation of thymic export causes accelerated decay of naive CD4 T cells in the periphery because of activation by environmental antigen. Proc Natl Acad Sci U S A (2008) 1.32
Modulation of dendritic cell function by naive and regulatory CD4+ T cells. J Immunol (2006) 1.31
Differentiation of human T(H)-17 cells does require TGF-beta! Nat Immunol (2008) 1.27
Homeostasis and T cell regulation. Curr Opin Immunol (2004) 1.26
Generalized immune activation as a direct result of activated CD4+ T cell killing. J Biol (2009) 1.22
Differential influences of the aryl hydrocarbon receptor on Th17 mediated responses in vitro and in vivo. PLoS One (2013) 1.21
Retrovirus-specificity of regulatory T cells is neither present nor required in preventing retrovirus-induced bone marrow immune pathology. Immunity (2008) 1.20
Emv2, the only endogenous ecotropic murine leukemia virus of C57BL/6J mice. Retrovirology (2012) 1.15
Regulation and function of innate and adaptive interleukin-17-producing cells. EMBO Rep (2012) 1.14
The many lives of IL-9: a question of survival? Nat Immunol (2012) 1.11
CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40. J Exp Med (2006) 1.07
B lymphocyte activation by coinfection prevents immune control of friend virus infection. J Immunol (2008) 1.06
Race between retroviral spread and CD4+ T-cell response determines the outcome of acute Friend virus infection. J Virol (2009) 1.05
Cross presentation of antigen on MHC class II via the draining lymph node after corneal transplantation in mice. J Immunol (2008) 1.04
Suppression of innate immune pathology by regulatory T cells during Influenza A virus infection of immunodeficient mice. J Virol (2010) 1.01
CD4 T-cell memory. Semin Immunol (2004) 1.01
Identification of early gene expression changes during human Th17 cell differentiation. Blood (2012) 0.99
Chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in CD5 levels in monoclonal CD8 T cells. J Immunol (2003) 0.99
T cell homeostasis in steady state and lymphopenic conditions. Immunol Lett (2006) 0.99
Are human endogenous retroviruses pathogenic? An approach to testing the hypothesis. Bioessays (2013) 0.98
Anatomical heterogeneity of memory CD4+ T cells due to reversible adaptation to the microenvironment. J Immunol (2004) 0.96
Functional specialization of memory Th cells revealed by expression of integrin CD49b. J Immunol (2006) 0.96
Noncognate interaction with MHC class II molecules is essential for maintenance of T cell metabolism to establish optimal memory CD4 T cell function. J Immunol (2007) 0.95
The concept of space and competition in immune regulation. Immunology (2004) 0.95
Negative selection by an endogenous retrovirus promotes a higher-avidity CD4+ T cell response to retroviral infection. PLoS Pathog (2012) 0.95
CD25+CD4+ regulatory T cells and memory T cells prevent lymphopenia-induced proliferation of naive T cells in transient states of lymphopenia. J Immunol (2006) 0.94
IL-22 Protects Against Liver Pathology and Lethality of an Experimental Blood-Stage Malaria Infection. Front Immunol (2012) 0.94
Roles for TGF-beta and programmed cell death 1 ligand 1 in regulatory T cell expansion and diabetes suppression by zymosan in nonobese diabetic mice. J Immunol (2010) 0.91
Mechanisms of control of acute Friend virus infection by CD4+ T helper cells and their functional impairment by regulatory T cells. J Gen Virol (2009) 0.91
Tumor necrosis factor-alpha regulation of insulin-like growth factor-I, type 1 IGF receptor, and IGF binding protein expression in cerebellum of transgenic mice. J Neurosci Res (2003) 0.91
Activation of CD8 T cells by antigen expressed in the pituitary gland. J Immunol (2002) 0.90
CD4 T cells guarantee optimal competitive fitness of CD8 memory T cells. Eur J Immunol (2004) 0.90
B cells and TCR avidity determine distinct functions of CD4+ T cells in retroviral infection. J Immunol (2011) 0.90
Distinct roles of CD4+ T cell subpopulations in retroviral immunity: lessons from the Friend virus mouse model. Retrovirology (2011) 0.89
IL-22 mediates goblet cell hyperplasia and worm expulsion in intestinal helminth infection. PLoS Pathog (2013) 0.86
IL-2-independent and TNF-α-dependent expansion of Vβ5+ natural regulatory T cells during retrovirus infection. J Immunol (2013) 0.86
The role of TNF/TNFR in organ-specific and systemic autoimmunity: implications for the design of optimized 'anti-TNF' therapies. Curr Dir Autoimmun (2002) 0.85
Negative impact of IFN-γ on early host immune responses to retroviral infection. J Immunol (2012) 0.85
Th17 cells: An orphan with influence. Immunol Cell Biol (2007) 0.84
Factors affecting the susceptibility of the mouse pituitary gland to CD8 T-cell-mediated autoimmunity. Immunology (2004) 0.83
Phenotypic and functional profiling of CD4 T cell compartment in distinct populations of healthy adults with different antigenic exposure. PLoS One (2013) 0.83
Counterpoise between the microbiome, host immune activation and pathology. Curr Opin Immunol (2013) 0.83
The influence of CD4 T-cell subsets on control of CD4 T-cell-mediated graft-versus-host disease. Immunology (2008) 0.80
Tumor and CD4 T-cell interactions: tumor escape as result of reciprocal inactivation. Blood (2003) 0.79
Immunology: Cause of death matters. Nature (2009) 0.77
Innate lymphoid cells and type 2 (th2) mediated immune responses - pathogenic or beneficial? Front Immunol (2011) 0.76
Transduction of naive CD4 T cells with kinase-deficient Lck-HIV-Tat fusion protein dampens T cell activation and provokes a switch to regulatory function. Eur J Immunol (2005) 0.75