Published in J Biol Chem on February 03, 2005
Complement evasion by human pathogens. Nat Rev Microbiol (2008) 4.24
Structure and flexibility within proteins as identified through small angle X-ray scattering. Gen Physiol Biophys (2009) 3.24
Staphylococcal manipulation of host immune responses. Nat Rev Microbiol (2015) 1.42
The Staphylococcus aureus extracellular adherence protein (Eap) adopts an elongated but structured conformation in solution. Protein Sci (2007) 1.18
Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus. J Exp Med (2006) 1.17
Surfactant protein A (SP-A)-mediated clearance of Staphylococcus aureus involves binding of SP-A to the staphylococcal adhesin eap and the macrophage receptors SP-A receptor 210 and scavenger receptor class A. J Biol Chem (2010) 1.14
More than one tandem repeat domain of the extracellular adherence protein of Staphylococcus aureus is required for aggregation, adherence, and host cell invasion but not for leukocyte activation. Infect Immun (2008) 1.09
eap Gene as novel target for specific identification of Staphylococcus aureus. J Clin Microbiol (2007) 1.03
STRALCP--structure alignment-based clustering of proteins. Nucleic Acids Res (2007) 1.01
Staphylococcus aureus secretes a unique class of neutrophil serine protease inhibitors. Proc Natl Acad Sci U S A (2014) 0.95
The extracellular adherence protein from Staphylococcus aureus inhibits the classical and lectin pathways of complement by blocking formation of the C3 proconvertase. J Immunol (2014) 0.88
Use of peptide-major histocompatibility complex tetramer technology to study interactions between Staphylococcus aureus proteins and human cells. Infect Immun (2007) 0.85
Staphylococcus aureus extracellular adherence protein triggers TNFα release, promoting attachment to endothelial cells via protein A. PLoS One (2012) 0.84
Stuck in the Middle: Fibronectin-Binding Proteins in Gram-Positive Bacteria. Front Microbiol (2016) 0.83
The Staphyloccous aureus Eap protein activates expression of proinflammatory cytokines. Infect Immun (2008) 0.82
Mapping the transcription start points of the Staphylococcus aureus eap, emp, and vwb promoters reveals a conserved octanucleotide sequence that is essential for expression of these genes. J Bacteriol (2007) 0.81
Repeating structures of the major staphylococcal autolysin are essential for the interaction with human thrombospondin 1 and vitronectin. J Biol Chem (2013) 0.80
Novel Evasion Mechanisms of the Classical Complement Pathway. J Immunol (2016) 0.80
Characterization of the fibrinogen binding domain of bacteriophage lysin from Streptococcus mitis. Infect Immun (2011) 0.79
Crystallization and X-ray diffraction analysis of the complement component-3 (C3) inhibitory domain of Efb from Staphylococcus aureus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.76
Expression, purification and crystallization of Streptococcus dysgalactiae-derived mitogen. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.75
Staphylococcus aureus Aggregation and Coagulation Mechanisms, and Their Function in Host-Pathogen Interactions. Adv Appl Microbiol (2016) 0.75
(1)H, (15)N, and (13)C resonance assignments of Staphylococcus aureus extracellular adherence protein domain 4. Biomol NMR Assign (2016) 0.75
The structural basis for inhibition of the classical and lectin complement pathways by S. Aureus extracellular adherence protein. Protein Sci (2017) 0.75
A phylogeny-driven genomic encyclopaedia of Bacteria and Archaea. Nature (2009) 15.06
Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab. Nature (2003) 6.78
Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex. Cancer Cell (2004) 6.12
Critical assessment of methods of protein structure prediction (CASP)-round V. Proteins (2003) 5.88
Functionally significant insulin-like growth factor I receptor mutations in centenarians. Proc Natl Acad Sci U S A (2008) 5.14
An open-and-shut case? Recent insights into the activation of EGF/ErbB receptors. Mol Cell (2003) 5.06
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain. PLoS Med (2006) 4.63
EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization. Mol Cell (2003) 4.23
Structure of the extracellular region of HER3 reveals an interdomain tether. Science (2002) 3.19
Mechanism of activation and inhibition of the HER4/ErbB4 kinase. Structure (2008) 2.79
Comparative genomics tools applied to bioterrorism defence. Brief Bioinform (2003) 2.44
Assessment of progress over the CASP experiments. Proteins (2003) 2.43
The other 90% of the protein: assessment beyond the Calphas for CASP8 template-based and high-accuracy models. Proteins (2009) 2.43
Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor. Science (2010) 2.12
Antibody elbow angles are influenced by their light chain class. J Mol Biol (2006) 1.96
Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165. J Biol Chem (2002) 1.89
Community genomic and proteomic analyses of chemoautotrophic iron-oxidizing "Leptospirillum rubarum" (Group II) and "Leptospirillum ferrodiazotrophum" (Group III) bacteria in acid mine drainage biofilms. Appl Environ Microbiol (2009) 1.86
The extracellular region of ErbB4 adopts a tethered conformation in the absence of ligand. Proc Natl Acad Sci U S A (2005) 1.84
Structure and Notch receptor binding of the tandem WWE domain of Deltex. Structure (2005) 1.76
Dystroglycan organizes axon guidance cue localization and axonal pathfinding. Neuron (2012) 1.76
Structural basis for ligand and heparin binding to neuropilin B domains. Proc Natl Acad Sci U S A (2007) 1.66
Interactions between Hedgehog proteins and their binding partners come into view. Genes Dev (2010) 1.54
Structure and stability of the ankyrin domain of the Drosophila Notch receptor. Protein Sci (2003) 1.54
Mutational analysis of Norrin-Frizzled4 recognition. J Biol Chem (2006) 1.48
Structure of a heparin-dependent complex of Hedgehog and Ihog. Proc Natl Acad Sci U S A (2006) 1.47
The mode of Hedgehog binding to Ihog homologues is not conserved across different phyla. Nature (2008) 1.47
Crystal structure of the CaV2 IQ domain in complex with Ca2+/calmodulin: high-resolution mechanistic implications for channel regulation by Ca2+. Structure (2008) 1.44
Netrin binds discrete subdomains of DCC and UNC5 and mediates interactions between DCC and heparin. J Biol Chem (2003) 1.37
The TB structural genomics consortium crystallization facility: towards automation from protein to electron density. Acta Crystallogr D Biol Crystallogr (2002) 1.24
A single ligand is sufficient to activate EGFR dimers. Proc Natl Acad Sci U S A (2012) 1.24
Transient mammalian cell transfection with polyethylenimine (PEI). Methods Enzymol (2013) 1.24
Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response. Proc Natl Acad Sci U S A (2010) 1.21
Mechanistic insights into the activation of oncogenic forms of EGF receptor. Nat Struct Mol Biol (2011) 1.21
All mammalian Hedgehog proteins interact with cell adhesion molecule, down-regulated by oncogenes (CDO) and brother of CDO (BOC) in a conserved manner. J Biol Chem (2010) 1.17
In vitro enzymatic characterization of near full length EGFR in activated and inhibited states. Biochemistry (2009) 1.16
A forward genetic screen in mice identifies Sema3A(K108N), which binds to neuropilin-1 but cannot signal. J Neurosci (2010) 1.10
Structural basis for heteromeric assembly and perinuclear organization of keratin filaments. Nat Struct Mol Biol (2012) 1.10
Kinetic and structural studies on interactions between heparin or heparan sulfate and proteins of the hedgehog signaling pathway. Biochemistry (2007) 1.10
Characterization of cytochrome 579, an unusual cytochrome isolated from an iron-oxidizing microbial community. Appl Environ Microbiol (2008) 1.03
A semi-quantitative, synteny-based method to improve functional predictions for hypothetical and poorly annotated bacterial and archaeal genes. PLoS Comput Biol (2011) 1.02
Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling. Proc Natl Acad Sci U S A (2011) 1.00
Mycobacterium tuberculosis RmlC epimerase (Rv3465): a promising drug-target structure in the rhamnose pathway. Acta Crystallogr D Biol Crystallogr (2004) 0.92
The role of viral population diversity in adaptation of bovine coronavirus to new host environments. PLoS One (2013) 0.92
Amino acid and structural variability of Yersinia pestis LcrV protein. Infect Genet Evol (2009) 0.90
Proteolytic processing of ErbB4 in breast cancer. PLoS One (2012) 0.90
Two translation products of Yersinia yscQ assemble to form a complex essential to type III secretion. Biochemistry (2012) 0.90
Selective high-affinity ligand antibody mimics for cancer diagnosis and therapy: initial application to lymphoma/leukemia. Clin Cancer Res (2007) 0.88
Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3. Protein Sci (2007) 0.88
A non-cleavable UmuD variant that acts as a UmuD' mimic. J Biol Chem (2006) 0.88
The ErbB4 extracellular region retains a tethered-like conformation in the absence of the tether. Protein Sci (2011) 0.87
Crystal structure of Caenorhabditis elegans HER-1 and characterization of the interaction between HER-1 and TRA-2A. Proc Natl Acad Sci U S A (2004) 0.84
Tyrosine phosphorylation of mig6 reduces its inhibition of the epidermal growth factor receptor. ACS Chem Biol (2013) 0.83
The significance of performance ranking in CASP--response to Marti-Renom et al. Structure (2002) 0.83
Memo is homologous to nonheme iron dioxygenases and binds an ErbB2-derived phosphopeptide in its vestigial active site. J Biol Chem (2007) 0.83
Discovery of novel non-synonymous SNP variants in 988 candidate genes from 6 centenarians by target capture and next-generation sequencing. Mech Ageing Dev (2013) 0.82
An Fc domain protein-small molecule conjugate as an enhanced immunomodulator. J Am Chem Soc (2014) 0.80
A strain of Yersinia pestis with a mutator phenotype from the Republic of Georgia. FEMS Microbiol Lett (2013) 0.78
Molecular dynamics simulations of transitions for ECD epidermal growth factor receptors show key differences between human and drosophila forms of the receptors. Proteins (2013) 0.78
Generating mammalian stable cell lines by electroporation. Methods Enzymol (2013) 0.75
SpaK/SpaR two-component system characterized by a structure-driven domain-fusion method and in vitro phosphorylation studies. PLoS Comput Biol (2009) 0.75
Identification of a thermo-regulated glutamine-binding protein from Yersinia pestis. Protein Pept Lett (2008) 0.75
A monkey wrench in the kinase machine. Nat Struct Mol Biol (2007) 0.75