Published in Gen Physiol Biophys on June 01, 2009
FoXS: a web server for rapid computation and fitting of SAXS profiles. Nucleic Acids Res (2010) 3.91
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SAXS ensemble refinement of ESCRT-III CHMP3 conformational transitions. Structure (2011) 2.24
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem (2009) 1.91
Accurate SAXS profile computation and its assessment by contrast variation experiments. Biophys J (2013) 1.83
Multidomain assembled states of Hck tyrosine kinase in solution. Proc Natl Acad Sci U S A (2010) 1.79
The structure and conformation of Lys63-linked tetraubiquitin. J Mol Biol (2009) 1.77
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat Struct Mol Biol (2011) 1.66
Advanced ensemble modelling of flexible macromolecules using X-ray solution scattering. IUCrJ (2015) 1.53
XRCC4 protein interactions with XRCC4-like factor (XLF) create an extended grooved scaffold for DNA ligation and double strand break repair. J Biol Chem (2011) 1.48
Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Mol Cell (2011) 1.38
Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control. Genes Dev (2012) 1.37
Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci U S A (2010) 1.37
How random are intrinsically disordered proteins? A small angle scattering perspective. Curr Protein Pept Sci (2012) 1.37
XLF regulates filament architecture of the XRCC4·ligase IV complex. Structure (2010) 1.33
Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. Biochemistry (2010) 1.32
Mechanism of DNA substrate recognition by the mammalian DNA repair enzyme, Polynucleotide Kinase. Nucleic Acids Res (2009) 1.24
Integrative structural modeling with small angle X-ray scattering profiles. BMC Struct Biol (2012) 1.22
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Solution structure, conformational dynamics, and CD4-induced activation in full-length, glycosylated, monomeric HIV gp120. J Virol (2012) 1.21
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The structure of the CRISPR-associated protein Csa3 provides insight into the regulation of the CRISPR/Cas system. J Mol Biol (2010) 1.16
The bacterial DnaC helicase loader is a DnaB ring breaker. Cell (2013) 1.14
Validation of macromolecular flexibility in solution by small-angle X-ray scattering (SAXS). Eur Biophys J (2012) 1.13
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A new structural framework for integrating replication protein A into DNA processing machinery. Nucleic Acids Res (2013) 1.12
Structural insights into the interaction of IL-33 with its receptors. Proc Natl Acad Sci U S A (2013) 1.09
Solution conformations of prototype foamy virus integrase and its stable synaptic complex with U5 viral DNA. Structure (2012) 1.07
Macromolecular docking restrained by a small angle X-ray scattering profile. J Struct Biol (2010) 1.07
Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell (2012) 1.05
Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA. Proc Natl Acad Sci U S A (2011) 1.04
Structural dynamics and single-stranded DNA binding activity of the three N-terminal domains of the large subunit of replication protein A from small angle X-ray scattering. Biochemistry (2010) 1.04
Structural insights into NHEJ: building up an integrated picture of the dynamic DSB repair super complex, one component and interaction at a time. DNA Repair (Amst) (2014) 1.03
Software for the high-throughput collection of SAXS data using an enhanced Blu-Ice/DCS control system. J Synchrotron Radiat (2010) 1.03
Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. J Mol Biol (2009) 1.02
Proteins at work: a combined small angle X-RAY scattering and theoretical determination of the multiple structures involved on the protein kinase functional landscape. J Biol Chem (2010) 1.02
Recovering a representative conformational ensemble from underdetermined macromolecular structural data. J Am Chem Soc (2013) 1.00
Structure, dynamics, evolution, and function of a major scaffold component in the nuclear pore complex. Structure (2013) 1.00
Solution structure of RNase P RNA. RNA (2011) 0.99
All-atom ensemble modeling to analyze small-angle x-ray scattering of glycosylated proteins. Structure (2013) 0.96
Structure and self-assembly of the calcium binding matrix protein of human metapneumovirus. Structure (2013) 0.95
The disordered C-terminal domain of human DNA glycosylase NEIL1 contributes to its stability via intramolecular interactions. J Mol Biol (2013) 0.93
X-ray solution scattering studies of the structural diversity intrinsic to protein ensembles. Biopolymers (2011) 0.92
Structural determinants of oligomerization of δ(1)-pyrroline-5-carboxylate dehydrogenase: identification of a hexamerization hot spot. J Mol Biol (2013) 0.92
Methods for SAXS-based structure determination of biomolecular complexes. Adv Mater (2014) 0.92
Scaffoldin conformation and dynamics revealed by a ternary complex from the Clostridium thermocellum cellulosome. J Biol Chem (2012) 0.91
Uncertainty in integrative structural modeling. Curr Opin Struct Biol (2014) 0.91
Integrative structure-function mapping of the nucleoporin Nup133 suggests a conserved mechanism for membrane anchoring of the nuclear pore complex. Mol Cell Proteomics (2014) 0.90
Repulsive guidance molecule is a structural bridge between neogenin and bone morphogenetic protein. Nat Struct Mol Biol (2015) 0.90
Molecular investigations of the structure and function of the protein phosphatase 1-spinophilin-inhibitor 2 heterotrimeric complex. Biochemistry (2011) 0.90
Flexibility in the PP1:spinophilin holoenzyme. FEBS Lett (2010) 0.89
Developing advanced X-ray scattering methods combined with crystallography and computation. Methods (2013) 0.88
Structurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response. Structure (2015) 0.87
Solution structure of the Atg1 complex: implications for the architecture of the phagophore assembly site. Structure (2015) 0.86
The immunoglobulin-like domains 1 and 2 of the protein tyrosine phosphatase LAR adopt an unusual horseshoe-like conformation. J Mol Biol (2011) 0.86
Role of IscX in iron-sulfur cluster biogenesis in Escherichia coli. J Am Chem Soc (2014) 0.86
Bipartite Topology of Treponema pallidum Repeat Proteins C/D and I: OUTER MEMBRANE INSERTION, TRIMERIZATION, AND PORIN FUNCTION REQUIRE A C-TERMINAL β-BARREL DOMAIN. J Biol Chem (2015) 0.85
Reconstruction of SAXS Profiles from Protein Structures. Comput Struct Biotechnol J (2013) 0.85
Structural studies of yeast Δ(1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): active site flexibility and oligomeric state. Biochemistry (2014) 0.85
Solution and crystallographic structures of the central region of the phosphoprotein from human metapneumovirus. PLoS One (2013) 0.84
Structure and primase-mediated activation of a bacterial dodecameric replicative helicase. Nucleic Acids Res (2015) 0.83
Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering. Biophys J (2015) 0.83
Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1. Biochemistry (2015) 0.83
Fusion of dioxygenase and lignin-binding domains in a novel secreted enzyme from cellulolytic Streptomyces sp. SirexAA-E. J Biol Chem (2013) 0.83
The effects of thermal disorder on the solution-scattering profiles of macromolecules. Biophys J (2014) 0.83
A novel 3' splice site recognition by the two zinc fingers in the U2AF small subunit. Genes Dev (2015) 0.82
Structure, dynamics, and specificity of endoglucanase D from Clostridium cellulovorans. J Mol Biol (2013) 0.82
A single amino-acid substitution allows endo-polygalacturonase of Fusarium verticillioides to acquire recognition by PGIP2 from Phaseolus vulgaris. PLoS One (2013) 0.82
Characterization of protein flexibility using small-angle x-ray scattering and amplified collective motion simulations. Biophys J (2014) 0.81
Substrate-specific reorganization of the conformational ensemble of CSK implicates novel modes of kinase function. PLoS Comput Biol (2012) 0.81
Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding. Nucleic Acids Res (2015) 0.81
Nucleic acid structure characterization by small angle X-ray scattering (SAXS). Curr Protoc Nucleic Acid Chem (2012) 0.81
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Structural and biophysical characterization of Staphylococcus aureus SaMazF shows conservation of functional dynamics. Nucleic Acids Res (2014) 0.80
The structure of human apolipoprotein A-IV as revealed by stable isotope-assisted cross-linking, molecular dynamics, and small angle x-ray scattering. J Biol Chem (2014) 0.80
Structural insights into the human metapneumovirus glycoprotein ectodomain. J Virol (2014) 0.80
Finding Our Way in the Dark Proteome. J Am Chem Soc (2016) 0.80
Cadherin flexibility provides a key difference between desmosomes and adherens junctions. Proc Natl Acad Sci U S A (2015) 0.80
HU multimerization shift controls nucleoid compaction. Sci Adv (2016) 0.80
Conformational transitions in human translin enable nucleic acid binding. Nucleic Acids Res (2013) 0.79
Small angle X-ray scattering analysis of Clostridium thermocellum cellulosome N-terminal complexes reveals a highly dynamic structure. J Biol Chem (2013) 0.79
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An Intrinsically Disordered APLF Links Ku, DNA-PKcs and XRCC4-DNA Ligase IV in an Extended Flexible Non-Homologous End Joining Complex. J Biol Chem (2016) 0.78
Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum. Acta Crystallogr F Struct Biol Commun (2015) 0.78
A Broad range of conformations contribute to the solution ensemble of the essential splicing factor U2AF(65). Biochemistry (2012) 0.78
Conformational changes in a hyperthermostable glycoside hydrolase: enzymatic activity is a consequence of the loop dynamics and protonation balance. PLoS One (2015) 0.78
Atomistic ensemble modeling and small-angle neutron scattering of intrinsically disordered protein complexes: applied to minichromosome maintenance protein. Biophys J (2011) 0.78
Asymmetric unwrapping of nucleosomal DNA propagates asymmetric opening and dissociation of the histone core. Proc Natl Acad Sci U S A (2016) 0.78
Structural and biochemical characterization of human PR70 in isolation and in complex with the scaffolding subunit of protein phosphatase 2A. PLoS One (2014) 0.77
Distinct structural features of the peroxide response regulator from group A Streptococcus drive DNA binding. PLoS One (2014) 0.77
Emerging applications of small angle solution scattering in structural biology. Protein Sci (2015) 0.77
Comparison of native and non-native ubiquitin oligomers reveals analogous structures and reactivities. Protein Sci (2016) 0.77
Investigating increasingly complex macromolecular systems with small-angle X-ray scattering. IUCrJ (2014) 0.77
Identifying and Visualizing Macromolecular Flexibility in Structural Biology. Front Mol Biosci (2016) 0.77
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A New Method for Determining Structure Ensemble: Application to a RNA Binding Di-Domain Protein. Biophys J (2016) 0.77
Atomistic modelling of scattering data in the Collaborative Computational Project for Small Angle Scattering (CCP-SAS). J Appl Crystallogr (2016) 0.77
An intrinsically disordered entropic switch determines allostery in Phd-Doc regulation. Nat Chem Biol (2016) 0.76
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Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS). Nat Methods (2009) 6.77
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Protein structure modeling with MODELLER. Methods Mol Biol (2008) 6.28
Structural genomics of the Thermotoga maritima proteome implemented in a high-throughput structure determination pipeline. Proc Natl Acad Sci U S A (2002) 6.00
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A structural model for unfolded proteins from residual dipolar couplings and small-angle x-ray scattering. Proc Natl Acad Sci U S A (2005) 2.28
Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase. Mol Cell (2006) 2.28
Degradation of cellulose substrates by cellulosome chimeras. Substrate targeting versus proximity of enzyme components. J Biol Chem (2002) 2.27
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase. Mol Cell (2005) 2.09
Integration of small-angle X-ray scattering data into structural modeling of proteins and their assemblies. J Mol Biol (2008) 2.05
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The SAXS solution structure of RF1 differs from its crystal structure and is similar to its ribosome bound cryo-EM structure. Mol Cell (2005) 1.53
The N terminus of Saccharomyces cerevisiae Msh6 is an unstructured tether to PCNA. Mol Cell (2007) 1.51
The crystal structures of EAP domains from Staphylococcus aureus reveal an unexpected homology to bacterial superantigens. J Biol Chem (2005) 1.37
The structural basis of signal transduction for the response regulator PrrA from Mycobacterium tuberculosis. J Biol Chem (2006) 1.34
Structural basis of cellulosome efficiency explored by small angle X-ray scattering. J Biol Chem (2005) 1.32
Protein disorder: conformational distribution of the flexible linker in a chimeric double cellulase. Biophys J (2005) 1.22
Folded-back solution structure of monomeric factor H of human complement by synchrotron X-ray and neutron scattering, analytical ultracentrifugation and constrained molecular modelling. J Mol Biol (2001) 1.21
The Staphylococcus aureus extracellular adherence protein (Eap) adopts an elongated but structured conformation in solution. Protein Sci (2007) 1.18
Suppression of experimental autoimmune encephalomyelitis by extracellular adherence protein of Staphylococcus aureus. J Exp Med (2006) 1.17
Activation of the LicT transcriptional antiterminator involves a domain swing/lock mechanism provoking massive structural changes. J Biol Chem (2005) 1.15
Solution structure of Grb2 reveals extensive flexibility necessary for target recognition. J Mol Biol (2001) 1.10
Solution structure of the complex between CR2 SCR 1-2 and C3d of human complement: an X-ray scattering and sedimentation modelling study. J Mol Biol (2005) 1.07
Quaternary structure built from subunits combining NMR and small-angle x-ray scattering data. Biophys J (2002) 1.06
Structural insights into the mechanism of formation of cellulosomes probed by small angle X-ray scattering. J Biol Chem (2004) 1.05
Structural and functional aspects of the sensor histidine kinase PrrB from Mycobacterium tuberculosis. Structure (2006) 1.02
The 15 SCR flexible extracellular domains of human complement receptor type 2 can mediate multiple ligand and antigen interactions. J Mol Biol (2006) 0.99
Activation mechanisms of transcriptional regulator CooA revealed by small-angle X-ray scattering. J Mol Biol (2004) 0.95
Structure determinations of human and chimaeric antibodies by solution scattering and constrained molecular modelling. Biochem Soc Trans (2008) 0.94
Insights into molecular plasticity of choline binding proteins (pneumococcal surface proteins) by SAXS. J Mol Biol (2006) 0.90
X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum. J Biol Chem (2005) 0.89
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution. Q Rev Biophys (2007) 9.07
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS). Nat Methods (2009) 6.77
Development of an improved four-site water model for biomolecular simulations: TIP4P-Ew. J Chem Phys (2004) 6.09
Structural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugation. Cell (2008) 6.07
FoXS: a web server for rapid computation and fitting of SAXS profiles. Nucleic Acids Res (2010) 3.91
XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations. Cell (2008) 3.14
Structures of SPOP-substrate complexes: insights into molecular architectures of BTB-Cul3 ubiquitin ligases. Mol Cell (2009) 2.84
A flexible interface between DNA ligase and PCNA supports conformational switching and efficient ligation of DNA. Mol Cell (2006) 2.23
Ku and DNA-dependent protein kinase dynamic conformations and assembly regulate DNA binding and the initial non-homologous end joining complex. J Biol Chem (2009) 1.91
Accurate SAXS profile computation and its assessment by contrast variation experiments. Biophys J (2013) 1.83
The structure and conformation of Lys63-linked tetraubiquitin. J Mol Biol (2009) 1.77
Implementation and performance of SIBYLS: a dual endstation small-angle X-ray scattering and macromolecular crystallography beamline at the Advanced Light Source. J Appl Crystallogr (2013) 1.69
ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. Nat Struct Mol Biol (2011) 1.66
Three-dimensional structure of the KChIP1-Kv4.3 T1 complex reveals a cross-shaped octamer. Nat Struct Mol Biol (2006) 1.64
Crosstalk between primase subunits can act to regulate primer synthesis in trans. Mol Cell (2005) 1.57
Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol (2010) 1.55
Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Mol Cell (2011) 1.38
Structures of inactive retinoblastoma protein reveal multiple mechanisms for cell cycle control. Genes Dev (2012) 1.37
Allosteric inhibition of complement function by a staphylococcal immune evasion protein. Proc Natl Acad Sci U S A (2010) 1.37
Superoxide dismutase from the eukaryotic thermophile Alvinella pompejana: structures, stability, mechanism, and insights into amyotrophic lateral sclerosis. J Mol Biol (2008) 1.32
Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states. Biochemistry (2010) 1.32
Comprehensive macromolecular conformations mapped by quantitative SAXS analyses. Nat Methods (2013) 1.29
Mechanism of ubiquitin ligation and lysine prioritization by a HECT E3. Elife (2013) 1.27
High-throughput SAXS for the characterization of biomolecules in solution: a practical approach. Methods Mol Biol (2014) 1.22
Structural analysis of flexible proteins in solution by small angle X-ray scattering combined with crystallography. J Struct Biol (2006) 1.21
Conformational trapping of mismatch recognition complex MSH2/MSH3 on repair-resistant DNA loops. Proc Natl Acad Sci U S A (2011) 1.21
Crystal structure of the bifunctional proline utilization A flavoenzyme from Bradyrhizobium japonicum. Proc Natl Acad Sci U S A (2010) 1.16
A molecular insight into complement evasion by the staphylococcal complement inhibitor protein family. J Immunol (2009) 1.16
Small-angle scattering and the structure of ambient liquid water. Proc Natl Acad Sci U S A (2010) 1.13
ModBase, a database of annotated comparative protein structure models and associated resources. Nucleic Acids Res (2013) 1.12
Modular structure of solubilized human apolipoprotein B-100. Low resolution model revealed by small angle neutron scattering. J Biol Chem (2006) 1.12
XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair. Biochem Cell Biol (2013) 1.09
Structural insights into the interaction of IL-33 with its receptors. Proc Natl Acad Sci U S A (2013) 1.09
Macromolecular docking restrained by a small angle X-ray scattering profile. J Struct Biol (2010) 1.07
Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. J Mol Biol (2008) 1.05
Structure of a glomulin-RBX1-CUL1 complex: inhibition of a RING E3 ligase through masking of its E2-binding surface. Mol Cell (2012) 1.05
Software for the high-throughput collection of SAXS data using an enhanced Blu-Ice/DCS control system. J Synchrotron Radiat (2010) 1.03
Structural insights into yeast DNA polymerase delta by small angle X-ray scattering. J Mol Biol (2009) 1.02
Structure of the noncatalytic domains and global fold of the protein disulfide isomerase ERp72. Structure (2009) 1.00
Crystal structure of the unliganded retinoblastoma protein pocket domain. Proteins (2011) 0.94
Mechanistic insights into the role of Hop2-Mnd1 in meiotic homologous DNA pairing. Nucleic Acids Res (2013) 0.89
Functional intersection of ATM and DNA-dependent protein kinase catalytic subunit in coding end joining during V(D)J recombination. Mol Cell Biol (2013) 0.88
The immunoglobulin-like domains 1 and 2 of the protein tyrosine phosphatase LAR adopt an unusual horseshoe-like conformation. J Mol Biol (2011) 0.86
Structural and functional characterization of CalS11, a TDP-rhamnose 3'-O-methyltransferase involved in calicheamicin biosynthesis. ACS Chem Biol (2013) 0.82
Structure, dynamics, and specificity of endoglucanase D from Clostridium cellulovorans. J Mol Biol (2013) 0.82
Small-angle X-ray scattering studies of the oligomeric state and quaternary structure of the trifunctional proline utilization A (PutA) flavoprotein from Escherichia coli. J Biol Chem (2011) 0.82
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Interdomain communication in the Mycobacterium tuberculosis environmental phosphatase Rv1364c. J Biol Chem (2009) 0.77